This document outlines topics related to general principles of pharmacology including: drugs that affect the nervous, respiratory, and cardiovascular systems; electrolytes; drugs used to treat myocardial infarction and allergic reactions; and drugs that affect the endocrine system. It provides information on specific medications for each topic, including their classifications, indications, and mechanisms of action.

1. GENERAL
PRINCIPLES OF
PHARMACOLOGY

2. Part 2 Topics
 Drugs used to affect the
 Nervous System
 Respiratory System
 Cardiovascular System
 Electrolytes
 Drugs used to treat MI
 Drugs used in Allergic Reations
 Drugs used to affect the Endocrine System
 Miscelaneous Drugs

3. Drugs Used to Affect the
Nervous System

5. Distribution of Sympathetic
Post-Ganglionic Fibers

6. Adrenergic Receptors

8. Autonomic Nervous System
Medications
 Drugs Affecting the Sympathetic
System:
 Adrenergic Receptors
 Adrenergic Agonists
 Adrenergic Antagonists
 Skeletal Muscle Relaxants

9. Epinephrine

10. Dopamine

11. Dobutamine

12. Autonomic Nervous System
Medications
 Drugs Affecting the
Parasympathetic System:
 Cholinergics
 Anticholinergics
 Ganglionic Blocking Agents
 Neuromuscular Blocking Agents
 Ganglionic Stimulating Agents

13. SLUDGE
 Salivation
 Lacrimation
 Urination
 Defecation
 Gastric Mobility
 Emisis

14. Atropine

15. Drugs Used to Affect the
Respiratory System

16. Antiasthmatic Medications

17. Albuterol

18. Drugs Used to Affect the
Cardiovascular System

19. Classifications of Cardiovascular
Drugs (1 of 2)
 Antidysrhythmics:
 Used to treat and prevent abnormal
cardiac rhythms.
 Antihypertensives:
 Drugs used to treat hypertension.

20. Classifications of Cardiovascular
Drugs (2 of 2)
 Hemostatic Agents:
 Drugs used to stop bleeding.
 Antihyperlipidemic Agents:
 Drugs used to treat high cholesterol.

21. Antidysrhythmics

22. Adenosine

23. Amiodarone

24. Bretylium

25. Lidocaine

26. Verapamil

27. Procainamide

28. Antihypertensives
 Diuretics
 Adrenergic inhibiting agents
 Angiotensin converting enzyme
inhibitors
 Angiotensin II receptor antagonists
 Calcium channel blockers
 Direct vasodilators

29. Hemostatic Agents
 Antiplatelets:
 Drugs that decrease the formation of
platelet plugs.
 Anticoagulants:
 Drugs that disrupt the clotting cascade.
 Thrombolytics:
 Drugs that act directly on thrombi to break
them down.

30. Antihyperlipidemics
 Drugs used to treat high blood
cholesterol.
 Examples:
 Lovastatin (mevacor).
 Simvastatin (zocor).

31. Electrolytes

32. Magnesium Sulfate

33. Calcium Chloride

34. Drugs used to Treat
Myocardial Infarction

35. MONA
 Morphine
 Oxygen
 Nitroglycerin
 Aspirin

36. Aspirin

37. Nitroglycerin

38. Morphine Sulfate

39. Naloxone

40. Furosemide

41. Drugs used in Allergic
Reactions

42. Diphenhydramine

43. Methylprednisolone

44. Dexamethasone

45. Drugs Used to Affect the
Endocrine System

47. Drugs Affecting the Pancreas
 Diabetes mellitus is the most important
disease involving the pancreas.
 Insulin—a substance that decreases
blood glucose level.
 Glucagon—a substance that increases
blood glucose level.

49. Oral Hypoglycemics
 Orinase (chlorpropamide)
 Glucotrol (glipizide)
 Micronase (glyburide)

50. Hyperglycemic Agents
 D50W is a sugar solution given
intravenously for acute
hypoglycemia.
 Glucagon is indicated for
emergency treatment when an
IV is unobtainable.

51. D50W

52. Glucagon

53. Drugs Used to Affect the
Diet

54. Many disease processes affect the
production, distribution, and utilization
of essential dietary nutrients.

56. Thiamine

57. Miscellaneous Drugs

58. Sodium Bicarbonate

59. Diazepam