This slide contains definition of pharmacognosy and reverse pharmacognosy, steps of pharmacognosy, parts of reverse pharmacognosy, comparison of pharmacognosy and reverse pharmacognosy, Selnergy, Selnergy in reverse pharmacognosy, application and advantages of reverse pharmacognosy, Selnergy on e-viniferin, Conclusion and Reference.
A brief description of some important topics of pharmaceutical chemistry like lead compounds bioactive compounds and prodrugs &soft drugs which are the base of pharmaceuticals.
Expected Questions for QCSH Subject (Quality Control & Standardization of Her...Dr-Jitendra Patel
In this ppt B. Pharmacy fourth year students will have basic idea about the important questions expected from quality control and standardization of herbals (QCSH) subject. And also some tips given at the last of video that how to prepare for this particular subject.
This slide contains definition of pharmacognosy and reverse pharmacognosy, steps of pharmacognosy, parts of reverse pharmacognosy, comparison of pharmacognosy and reverse pharmacognosy, Selnergy, Selnergy in reverse pharmacognosy, application and advantages of reverse pharmacognosy, Selnergy on e-viniferin, Conclusion and Reference.
A brief description of some important topics of pharmaceutical chemistry like lead compounds bioactive compounds and prodrugs &soft drugs which are the base of pharmaceuticals.
Expected Questions for QCSH Subject (Quality Control & Standardization of Her...Dr-Jitendra Patel
In this ppt B. Pharmacy fourth year students will have basic idea about the important questions expected from quality control and standardization of herbals (QCSH) subject. And also some tips given at the last of video that how to prepare for this particular subject.
Introduction of medicinal chemistry
History of medicinal chemistry
Physicochemical parameters and biological action
Stereochemical parameters and Biological action
Standardization of herbal drugs refers to “confirmation of its identity and determination of its quality, purity and detection of nature of adulterant by various parameters”.
By Vaishnavi Nikte ( B pharmacy )
slides includes all about Clinical Research Pharmacovigilance & Phyto Research. Useful for pharmacy student as well as Clinical research field people also includes pharmacognosy basics for herbal drug discovery.
Crude drugs: A general view of their origin, distributions, cultivation, collection, drying and
storage, commerce and quality control.
a) Classification of drugs.
b) Preparation of drugs for commercial market
c) Evaluation of crude drugs.
d) Drug adulteration.
Herbal medicine is the use of plants or plant extracts for medicinal purposes (especially plants that are not part of the normal diet).
Phytonutrient or nutraceutical or functional food
Natural substances that aid the body to maintaining health and combating disease such as anthocyanidins, isoflavones and carotenoids.
Natural product : is biosynthetic substances produced by living cells.
Crude Drug: It’s a medically useful drug of plant or animal origin without any further processing or modification.
Strategy for Preparation of GPAT
How to Start?
What to Refer?
Preparation of Pharmacology for GPAT
Understanding the Bonding between Subjects
What points to cover?
Points of Remembrance…
Homoeopathic Drug Standardization through Biological Evaluation Future Perspe...ijtsrd
There is a scarcity of chemico analytical method of standardization of high dilution of homoeopathic drugs. Homoeopathic medicines include any drug which are prepared by the methods given in homoeopathic pharmacopoeias. Efficacy of homoeopathic medicines are obtained by clinical use, from homoeopathic authenticated literature and research. Vineeta | Atul Kumar Singh "Homoeopathic Drug Standardization through Biological Evaluation- Future Perspective" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-6 , October 2020, URL: https://www.ijtsrd.com/papers/ijtsrd33596.pdf Paper Url: https://www.ijtsrd.com/medicine/other/33596/homoeopathic-drug-standardization-through-biological-evaluation-future-perspective/vineeta
Introduction of medicinal chemistry
History of medicinal chemistry
Physicochemical parameters and biological action
Stereochemical parameters and Biological action
Standardization of herbal drugs refers to “confirmation of its identity and determination of its quality, purity and detection of nature of adulterant by various parameters”.
By Vaishnavi Nikte ( B pharmacy )
slides includes all about Clinical Research Pharmacovigilance & Phyto Research. Useful for pharmacy student as well as Clinical research field people also includes pharmacognosy basics for herbal drug discovery.
Crude drugs: A general view of their origin, distributions, cultivation, collection, drying and
storage, commerce and quality control.
a) Classification of drugs.
b) Preparation of drugs for commercial market
c) Evaluation of crude drugs.
d) Drug adulteration.
Herbal medicine is the use of plants or plant extracts for medicinal purposes (especially plants that are not part of the normal diet).
Phytonutrient or nutraceutical or functional food
Natural substances that aid the body to maintaining health and combating disease such as anthocyanidins, isoflavones and carotenoids.
Natural product : is biosynthetic substances produced by living cells.
Crude Drug: It’s a medically useful drug of plant or animal origin without any further processing or modification.
Strategy for Preparation of GPAT
How to Start?
What to Refer?
Preparation of Pharmacology for GPAT
Understanding the Bonding between Subjects
What points to cover?
Points of Remembrance…
Homoeopathic Drug Standardization through Biological Evaluation Future Perspe...ijtsrd
There is a scarcity of chemico analytical method of standardization of high dilution of homoeopathic drugs. Homoeopathic medicines include any drug which are prepared by the methods given in homoeopathic pharmacopoeias. Efficacy of homoeopathic medicines are obtained by clinical use, from homoeopathic authenticated literature and research. Vineeta | Atul Kumar Singh "Homoeopathic Drug Standardization through Biological Evaluation- Future Perspective" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-4 | Issue-6 , October 2020, URL: https://www.ijtsrd.com/papers/ijtsrd33596.pdf Paper Url: https://www.ijtsrd.com/medicine/other/33596/homoeopathic-drug-standardization-through-biological-evaluation-future-perspective/vineeta
Monographs of herbal drugs: General parameters of
monographs of herbal drugs and comparative study in IP, USP,
Ayurvedic Pharmacopoeia, Siddha and Unani Pharmacopoeia,
American herbal pharmacopoeia, British herbal pharmacopoeia,
WHO guidelines in quality assessment of herbal drugs.
Phytochemical Screening of Methanolic Extracts of Different Parts of Rudraksh...Pratyush Kumar Das
Since time immemorial plants have played a vital role in the
field of health care and medicines. There are many plants with high medicinal values among which Elaeocarpus ganitrus (Rudraksh) holds utmost importance, both scientifically as well as spiritually. The different parts of a rudraksh tree have high concentrations of important phytochemical constituents thus adding to its medicinal value. This work is focused on phytochemical screening of methanolic extracts from the epicarp, endocarp of the seed and bark sample of rudraksh tree and their comparison to justify the high medicinal efficacy of the plant.
75%-90% of the population in developing nations rely on herbal medicine as their only health care.
Medicinal herbs are sold alongside vegetables in village markets.
Practitioners of herbal medicine undergo extensive training to learn the plants, their uses, and preparation of remedies.
Description about what is pharmacopoeia? different pharmacopoeia and there edition. What is monograph and there comparative studies in different pharmacopoeias along with monograph format in per different pharmacopoies.
Similar to Pharmacognosy iii syllabus f inal yr b pharm-cbcs 2020-21 (20)
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
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Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
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- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
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Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
The Gram stain is a fundamental technique in microbiology used to classify bacteria based on their cell wall structure. It provides a quick and simple method to distinguish between Gram-positive and Gram-negative bacteria, which have different susceptibilities to antibiotics
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...
Pharmacognosy iii syllabus f inal yr b pharm-cbcs 2020-21
1. AC 14.6.2018
Item Number : 4.53
UNIVERSITY OF MUMBAI
Bachelor of Pharmacy
B. Pharm. Choice Based Credit System (CBCS)
Third Year B. Pharm. and Final Year B. Pharm
( Semester V to Semester VIII ),
from Academic Year 2018 -19 and 2019-20
(As per Choice Based Credit and Grading System with
effect from the academic year 2016–2017)
2. 14. The Organic Chemistry of Drug Design and Drug Action, Richard B.Silverman, Academic Press.
15. Foye’s Principles of Medicinal Chemistry, Thomas L. Lemke, David A Williams, Lippincott Williams & Wilkins.
16. Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry, John M. Beale, John H. Block, Lippincott
Williams & Wilkins.
17. Medicinal Chemistry, Ashutosh Kar, New Age International Publishers.
18. Introduction to Medicinal Chemistry, Alex Gringauz, Wiley.
19. The Organic Chemistry of Drug Synthesis, Daniel Lednicer, Lester A. Mitscher, John Wiley and Sons.
20. Pharmaceutical Chemistry, Volume 1, Organic Synthesis, H. J. Roth & A. Kleemann, Ellis Horwood Series in Pharmaceutical
Technology, Halsted Series.
21. Synthesis of Essential Drugs, Ruben Vardanyan and Victor Hruby, Elsevier.
Pharmaceutical Substances: Syntheses, Patents, Applications, Kleemann& Engel, Thieme Publications.
BPH_C_702_T – Pharmacognosy III- (4 Hr/Wk)
Course Objectives
1. To introduce the learner to the chemistry, sources, cultivation and collection of crude drugs containing phytoconstituents like
steroidal, triterpenoidal, anthraquinone, flavonoid glycosides and alkaloids.
2. To introduce the learner to the biosynthesis of alkaloids obtained from different amino acids
3. To introduce the learner to glycoproteins with the representative examples and their utility in diagnosis or therapeutics.
4. To make the learner aware of regulatory requirements for manufacture and sale of Ayurvedic, Siddha and Unani (ASU) Medicines
and Phytopharmaceuticals, monographs of herbal drugs
5. To make the learner understand formulation aspects and challenges of Herbal formulations, standardization and interactions of
drugs of natural origin
6. To apply the spectroscopic techniques in characterization of phytoconstituents of both aliphatic and aromatic nature
Course Outcomes
Upon completion of the course student will be able to:
1. Write the source, composition, general methods of extraction, evaluation, chemical tests, therapeutic uses of crude drugs containing
phytoconstituents like steroidal, triterpenoidal, anthraquinone, flavonoidal glycosides, alkaloids glycoproteins.
2. Write the biosynthesis of biosynthesis of alkaloids obtained from different amino acids
3. Understand regulatory requirements for manufacture and sale of Ayurvedic, Siddha and Unani (ASU) Medicines and
Phytopharmaceuticals, monographs of herbal drugs
4. Apply the knowledge of excipients from natural origin and pharmaceutical technology to herbal formulation and understand the
challenges in herbal formulation
5. Understand the concept of herbal drug standardization and its application to herbal formulation
6. Apply the knowledge of pharmacology to understand pharmacodynamic and pharmacokinetic interactions of herbal drugs with food
7. Apply spectroscopic techniques to characterize small molecules both from the categories of aromatic and aliphatic nature
No. Details Hours
1 Steriodal and Triterpenoidal glycosides
Detailed study of drugs with respect source, chemistry, and therapeutic application of the following drugs –
Liquorice, Asparagus, Dioscorea, Fenugreek, Brahmi, Ginseng
Introduction to cardiac glycosides with respect to their classification, chemistry & general chemical tests.
Detailed study of drugs with respect source, chemistry cultivation and collection, preparation & biopotential
of the following drugs –
Digitalis lanata, Digitalis purpurea, Squill
Extraction, Identification and Analysis of Phytoconstituents –
Liquorice constituents
Commercial application of Diosgenin
Interactive Session
Potency, marketed preparation of all cardiac glycosides
Composition and indication of Fenugreek containing formulations
6
1
2 Alkaloids
Introduction to alkaloids - Classification, properties, general methods of extraction.
Study of following drugs containing alkaloids with respect to their sources, chemistry (structures), salient
features of extraction and specific tests for detection (if any) and therapeutic applications of:
a. Alkaloidal Amines – Ephedra, colchicum
b. Tropane - Datura, Coca, Ashwagandha
c. Indole - Rauwolfia, Vinca, Ergot
8
3. d. Steroidal –Kurchi
e. Quinazoline – Vasaka
f. Benzyl isoquinoline – Opium
g. Isoquinoline - Ipecac, Berberis aristata
h. Quinoline - cinchona
i. Pyridine-Piperidine –Pepper, Tobacco
j. Purine - Tea, Coffee, Cocoa
k. Imidazole – Pilocarpus
l. Glycoalkaloids- Solanum
Isolation, Identification and Analysis of Phytoconstituents
Piperine, Caffeine
Interactive Session
Market products and their therapeutic uses of Atropine, Pilocarpine, Vasaka, Kurchi, Ephedra, Pepper
1
1
3 Biosynthesis of lysergic acid, tropane alkaloids, emetine, quinine, 2
4 Glycoproteins – Castor, Pea and Oats 2
5 Glycosides
a) Anthracene derivative – Study of aloes, senna, rhubarb, with respect to Occurrence, chemistry, salient
features of cultivation, collection, preparation, chemical test and uses.
b) Source, chemistry and uses of Rubia, St. John`s wort
Occurrence, Chemistry, Test and Uses of
a) Isothiocyanate – Brassica, cabbage
b) Cyanogenetic - bitter almond, wild cherry bark, Biosynthesis of amygdaline
Isolation, Identification and Analysis of Phytoconstituents – Anthraquinone- Aloe emodin
3
2
6 Detailed study of Flavonoids and Coumarins:
a. Introduction, classification, chemical tests occurrence & their biopotential as exemplified by
Orange Peel, Soyabean, Buckwheat, Psoralea.
b. Monomeric, dimeric and related phenylpropanoid derivatives e.g.,
lignans- Podophyllum
Isolation, Identification and Analysis of Phytoconstituents - Rutin
3
7 Interactions with DONO :
Concept of pharmacokinetic interaction and pharmacodynamic interactions
herb- drug interactions – 3 examples each of synergistic and antagonistic interactions
herb- food interactions – 3 examples each of synergistic and antagonistic interactions
eg . Hypercium, Liquorice, Coffee, Ginseng, Ginkgo biloba, Digitalis, Garlic, Pepper & Ephedra.
3
8 Use of spectroscopy techniques in characterization of phytoconstituents.
a. Citral b. Rutin c. Gallic acid
2
9 Standardization of herbal drugs using various type of markers with examples.
Application of various chromatographic techniques in standardization of herbal products with two examples.
Stability testing of herbal medicines with respect to marker analysis.
Interactive session
Standardization of polyherbal formulation with respect to respective marker constituents emphasizing on
simultaneous estimation.
3
1
10 Monograph of herbal drugs & excipients in Indian Pharmacopoeia (Two examples each)
Interactive session
Comparative study of herbal monographs in IP, USP, Ayurvedic Pharmacopoeia, American herbal
Pharmacopoeia, British herbal Pharmacopoeia.
2
2
11 Regulatory Issues - ASU formulations, patent and proprietary medicine and Phytopharmaceuticals
Schedule T & Y of Drugs & Cosmetics Act for ASU drugs and phytopharmaceuticals
2
12 Study of herbal formulations & Ayurvedic formulations
a. Ayurvedic Formulations –Introduction to Ayurvedic formulations like aristas, asava, gutika,taila, churna,
avaleha, bhasma, ghrita.
b. Introduction to the concept of detoxification in Ayurveda (2eg).
c. c. Herbal formulations: Challenges in the preparation and evaluation of Herbal tablets, capsules, liquid oral,
semisolid dosage forms
3
4. d. NDDS of Herbal medicine: Limitation of conventional formulations, challenges in development of NDDS of
Herbal medicine, Phytosomes with one example each
Interactive session
Phytopharmaceuticals in the market: Study of any two formulations under each category with respect to their
ingredients used and activities / claims of each ingredient used in them
1
TOTAL 48
Books:
Latest editions of the following books to be adopted.
1. Trease D. & Evans W.C.: Text Book of Pharmacognosy: W.B. Saunders.
2. Tyler V. E. Brady L. R. & Robbers J. E.: Pharmacognosy; Lea Feibger, USA.
3. Wallis T. E.; Text Book of Pharmacognosy; CBS Publishers, Delhi.
4. Kokate C. K., Purohit A. P. & Gokhale S. B.: Pharmacognosy; Nirali Publications, Pune.
5. Harbone J. B.: Phytochemical Methods: A guide to modern techniques Analysis: Chapman & Hall, London.
6. Bruneton J.: Pharmacognosy, Phytochemistry, Medicinal Plants: Intercept Limited.
7. Vasudevan T. N. & Laddha K. S.: A Textbook of Pharmacognosy, Vrinda Publication House, Jalgaon.
8. The Indian Pharmacopeia: The Controller of Publication; Delhi.
9. R. S. Guad, S. J. Surana, G. S. Talele, S. G. Talele, Mr. S. B. Gokhale. Natural Excipients, Pragati Books Pvt. Ltd., 2006
10. Biren Shah, Avinash Seth, Textbook of Pharmacognosy and Phytochemistry , Elsevier Health Sciences,
11. Ashutosh Kar, Pharmacognosy And Pharmacobiotechnology, New Age International, 2003
12. Quality Control Methods for Medicinal Plant Materials, World Health Organization World Health Organization, 1998 - Botanical
drug industry
13. WHO Monographs on Selected Medicinal Plants, World Health Organization World Health Organization, 1999
14. ESCOP Monographs: The Scientific Foundation for Herbal Medicinal Products, ESCOP, European Scientific Cooperative on
Phytotherapy, Thieme, 2003 -
15. Herbal Drugs and Phytopharmaceuticals: A Handbook for Practice on a Scientific Basis, Max Wichtl CRC Press, 2004 - Health &
Fitness
16. Pulok K. Mukherjee Evidence-Based Validation of Herbal Medicine, Elsevier, 17-Feb-2015
17. Adverse Effects of Herbal Drugs 2, Springer Science & Business Media, 06-Dec-2012
18. Quality Control of Herbal Drugs: An Approach to Evaluation of Botanicals, Pulok K. Mukherjee Business Horizons, 2002
19. Brain K. R. & Turner T. D.: The Practical Evaluation of Phytopharmaceuticals: Wright, Scientica, Bristol.
20. Iyengar M. A. & Nayak S. G.: Anatomy of Crude Drugs: Manipal Power Press, Manipal
21. Iyengar M. A.: Pharmacognosy of Powdered Drugs; Manipal Power Press, Manipal
BPH_C_703_T – Pharmaceutical Analysis III- (4 Hr/Wk)
Course Objectives
On completion of this course, the learner should be able to apply the principles of spectroscopy for multicomponent analysis and describe
working principle, instrumentation and applications of chromatographic and characterization techniques.
Course Outcomes
The learner should be able to:
1. Explain various methods used for multicomponent analysis of drugs by UV spectroscopy.
2. Summarize chromatographic and hyphenated techniques used for the separation, identification and quantification of analytes.
3. Describe the working of proton 1
H NMR spectroscopy and mass spectrometry.
4. Interpret spectral data to predict structure of a given compound.
5. Summarize the parameters of ICH guidelines for analytical method validation.
No. Details Hours
1.0 Multicomponent analysis by UV Spectroscopy 4
1.1 Assay as a single component sample
Corrected interference
Assay after solvent extraction
Simultaneous Equation method
4