This document discusses various antifungal drugs including polyenes like amphotericin B and nystatin, echinocandins like caspofungin, and the heterocyclic benzofuran griseofulvin. It describes their mechanisms of action, spectra of activity, pharmacokinetics, therapeutic uses, and adverse effects. Amphotericin B is a broad-spectrum antifungal that is fungicidal but highly nephrotoxic. Caspofungin inhibits glucan synthase in fungal cell walls. Griseofulvin binds microtubules to treat dermatophytosis.
In this section, we describe Various types of Penicillin Antibiotics and most of the slides are cited from:
1- Lippincott's Illustrated Pharmacology
2- KD Triphati Pharmacology
3- Basic Katzung Pharmacology
This document discusses different classes of beta-lactam antibiotics including cephalosporins, monobactams, and carbapenems. It describes the chemistry, mechanisms of action, spectra of activity, pharmacokinetics, uses, and adverse effects of various drugs within each class. First, second, third, fourth, and fifth generation cephalosporins are compared in terms of their antimicrobial spectra and examples are provided. Monobactams such as aztreonam are noted to have activity against aerobic gram-negative rods. Carbapenems like imipenem and meropenem have broad-spectrum gram-positive and gram-negative activity including anaerobes.
Beta lactamase inhibitors such as clavulanic acid, sulbactam, tazobactam, and avibactam work to inhibit beta-lactamase enzymes produced by bacteria that provide resistance to beta-lactam antibiotics like penicillins. They bind to and inactivate the beta-lactamase enzymes. When combined with beta-lactam antibiotics, the inhibitors can help the antibiotics overcome resistance and be effective against infections. Common combinations include amoxicillin-clavulanic acid, piperacillin-tazobactam, and ceftazidime-avibactam which are used to treat a variety of bacterial infections.
This document discusses antibacterial agents, specifically penicillins. It provides background on penicillins, noting they contain a beta-lactam ring that inhibits bacterial cell wall formation. Examples of penicillins are discussed, including benzylpenicillin, phenoxymethylpenicillin, ampicillin, and amoxicillin. Resistance via bacterial production of beta-lactamase is also mentioned.
Introduction to microbiology, Bacterial Cell wall, Difference between Gram p...Zunaira Gillani
Introduction to microbiology, Brief History of Microbiology, Structure of Bacteria, Size and Shape of Bacteria,Bacterial Cell wall, Difference between Gram positive and Gram negative, Fungi , Classification of fungi, Structure and Characteristics of fungi, , Algae, Types of Algae, Protozoan, Virus, virion, Examples of virus
The presentation include semisynthetic penicillin introduction and classification.
Contents
Semisynthetic penicillins- Introduction
Classification
Acid-resistant alternative to Penicillin G
Penicillinase- resistant penicillins
Extended spectrum penicillins
This document discusses various antifungal drugs including polyenes like amphotericin B and nystatin, echinocandins like caspofungin, and the heterocyclic benzofuran griseofulvin. It describes their mechanisms of action, spectra of activity, pharmacokinetics, therapeutic uses, and adverse effects. Amphotericin B is a broad-spectrum antifungal that is fungicidal but highly nephrotoxic. Caspofungin inhibits glucan synthase in fungal cell walls. Griseofulvin binds microtubules to treat dermatophytosis.
In this section, we describe Various types of Penicillin Antibiotics and most of the slides are cited from:
1- Lippincott's Illustrated Pharmacology
2- KD Triphati Pharmacology
3- Basic Katzung Pharmacology
This document discusses different classes of beta-lactam antibiotics including cephalosporins, monobactams, and carbapenems. It describes the chemistry, mechanisms of action, spectra of activity, pharmacokinetics, uses, and adverse effects of various drugs within each class. First, second, third, fourth, and fifth generation cephalosporins are compared in terms of their antimicrobial spectra and examples are provided. Monobactams such as aztreonam are noted to have activity against aerobic gram-negative rods. Carbapenems like imipenem and meropenem have broad-spectrum gram-positive and gram-negative activity including anaerobes.
Beta lactamase inhibitors such as clavulanic acid, sulbactam, tazobactam, and avibactam work to inhibit beta-lactamase enzymes produced by bacteria that provide resistance to beta-lactam antibiotics like penicillins. They bind to and inactivate the beta-lactamase enzymes. When combined with beta-lactam antibiotics, the inhibitors can help the antibiotics overcome resistance and be effective against infections. Common combinations include amoxicillin-clavulanic acid, piperacillin-tazobactam, and ceftazidime-avibactam which are used to treat a variety of bacterial infections.
This document discusses antibacterial agents, specifically penicillins. It provides background on penicillins, noting they contain a beta-lactam ring that inhibits bacterial cell wall formation. Examples of penicillins are discussed, including benzylpenicillin, phenoxymethylpenicillin, ampicillin, and amoxicillin. Resistance via bacterial production of beta-lactamase is also mentioned.
Introduction to microbiology, Bacterial Cell wall, Difference between Gram p...Zunaira Gillani
Introduction to microbiology, Brief History of Microbiology, Structure of Bacteria, Size and Shape of Bacteria,Bacterial Cell wall, Difference between Gram positive and Gram negative, Fungi , Classification of fungi, Structure and Characteristics of fungi, , Algae, Types of Algae, Protozoan, Virus, virion, Examples of virus
The presentation include semisynthetic penicillin introduction and classification.
Contents
Semisynthetic penicillins- Introduction
Classification
Acid-resistant alternative to Penicillin G
Penicillinase- resistant penicillins
Extended spectrum penicillins
Cell wall inhibitors like β-lactam antibiotics inhibit the final step of bacterial cell wall synthesis. The penicillins interfere with transpeptidation by binding to penicillin-binding proteins. This prevents cross-linking of peptidoglycan chains, weakening the cell wall. Extended-spectrum penicillins are effective against gram-positive and some gram-negative bacteria but resistance has increased. Adverse effects include hypersensitivity reactions, diarrhea, and nephritis, particularly with methicillin which is no longer used.
This document discusses quinolones, a class of synthetic antimicrobial compounds. It begins by introducing nalidixic acid, the first quinolone, and how later fluorination led to more potent fluoroquinolone derivatives. Mechanism of action is described as inhibition of bacterial DNA gyrase and topoisomerase, preventing DNA replication. Adverse effects include tendonitis, CNS effects, and QT prolongation with some agents. Therapeutic uses include urinary tract infections, gonorrhea, respiratory infections, and more. Resistance develops via mutations impairing drug binding or drug efflux.
This document provides an overview of fungi. It discusses that fungi are eukaryotic organisms classified in the kingdom Fungi. They can exist as molds, yeasts, or dimorphic fungi. Fungi have cell walls containing chitin and reproduce asexually through spores or budding or sexually through the fusion of hyphae. The document outlines the morphological characteristics, differences from bacteria, classification systems based on cell structure and reproduction, and types of fungal infections like superficial, cutaneous, subcutaneous, and systemic mycoses.
Ciprofloxacin is a synthetic broad spectrum fluoroquinolone antibiotic that binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. It is more active against Gram-negative bacteria. Ciprofloxacin lactate is manufactured by condensing Fluoroquinolonic Acid with piperazine and other compounds, then treating it with lactic acid to form Ciprofloxacin Lactate. The global market for ciprofloxacin hcl is growing due to its increasing use to treat infections in the urogenital, respiratory, and gastrointestinal systems as well as typhoid, bone and joint infections, and more.
This document discusses antibiotics and their properties. It describes how antibiotics are chemical substances produced by microorganisms that kill or inhibit pathogenic bacteria without harming host tissue. An ideal antibiotic should have broad-spectrum activity, be effective at low concentrations, kill bacteria rather than just inhibiting growth, selectively target pathogens, and not induce bacterial resistance. The document then discusses specific classes of antibiotics like tetracyclines, penicillins, and cephalosporins, outlining their mechanisms of action, properties, uses, and mechanisms of resistance.
This document provides information about virus structure and classification. It begins with the history of virology and defines viruses. It describes the differences between bacteria and viruses, and between DNA and RNA viruses. It outlines the characteristics, structure, replication process, and reaction to physical and chemical agents of viruses. It discusses viral morphology, classification based on shape and presence of an envelope. It also covers bacteriophage structure and important human viruses classified by genome type and associated disease.
Antibacterials and their mode of actionMidhun M Nair
This document discusses the history and classification of antibacterial agents. It begins by defining an antibacterial as an agent that interferes with bacterial growth and reproduction. It then provides a brief history of antibacterial use dating back to ancient Egypt and Greece. The document outlines several important discoveries and individuals that advanced the field, such as Alexander Fleming, Florey, Chain, and Selman Waksman. It proceeds to classify antibacterials according to their spectrum of activity (broad vs narrow), effect on bacteria (bactericidal vs bacteriostatic), and mode of action (inhibiting cell wall, membrane, protein, nucleic acid synthesis etc.). The classifications and examples are described in detail in the document.
This document discusses antigens and epitopes. It defines antigens as substances that induce an immune response and react with immune system products. Antigens include molecules like proteins, polysaccharides, and lipids. Epitopes are specific regions of antigens that interact with antibodies. A single antigen can have multiple epitopes that each bind to a different antibody. Factors that determine antigenicity include size, chemical nature, complexity, structural stability, foreignness, and an individual's genetic makeup.
1) Antibacterial agents, also known as antibiotics, are used to inhibit bacterial growth or kill bacteria. They are commonly classified based on their chemical origin or biological effect.
2) Antibacterial agents work by targeting differences between bacterial and animal cells, interfering with bacterial cell wall synthesis, protein synthesis, nucleic acid synthesis, or folic acid synthesis.
3) Common mechanisms of resistance include enzymatic modification of the antibacterial agent, mutations that prevent binding, or active efflux of the agent from the bacterial cell.
The document discusses antimicrobial agents and mechanisms of resistance. It covers several topics:
1. Definitions and classifications of antibiotics based on chemical structure, source, mechanism of action, and spectrum.
2. Mechanisms of antibiotic resistance in bacteria including production of enzymes to destroy drugs and genetic/non-genetic resistance.
3. Approaches to address rising antibiotic resistance such as appropriate use and preventing overprescription.
The document discusses the classification and development of quinolone drugs. It notes that first generation drugs like nalidixic acid had minimal serum levels, while second generation drugs like ciprofloxacin had increased gram-negative and systemic activity. Third generation drugs like levofloxacin expanded activity to gram-positive bacteria and atypical pathogens. Fourth generation drugs like trovafloxacin added significant activity against anaerobes. Newer fluoroquinolones have broad-spectrum bactericidal activity and good safety profiles.
Fungi reproduce through three main methods: vegetative reproduction through fragmentation or budding, asexual reproduction through spores produced on specialized structures, and sexual reproduction through the fusion of haploid gametes. Asexual reproduction can be endogenous through spores produced inside sporangia or exogenous through spores (conidia) produced on conidiophores. During sexual reproduction, haploid gametes from two parents fuse and undergo meiosis to produce diploid spores, restoring the haploid phase.
Anti protozoal and anti malarial drugsThiru Vinoth
Metronidazole is the prototype nitroimidazole anti-protozoal drug used to treat amoebiasis and other anaerobic bacterial infections. It is well absorbed orally and widely distributed throughout the body, with an elimination half-life of around 8 hours. Metronidazole's mechanism of action involves reduction of its nitro group by redox proteins in anaerobic organisms, which disrupts their energy metabolism. It is generally well tolerated but can cause adverse effects like nausea, metallic taste, and peripheral neuropathy with prolonged use. Metronidazole interacts with alcohol and some other drugs due to its metabolism.
Cephalosporins are a class of β-lactam antibiotics derived from fungi. They are classified into generations based on their spectrum of activity, with later generations having broader spectra. They work by binding penicillin-binding proteins. Resistance can develop via target modification or β-lactamase production. Newer generations have activity against MRSA and expanded gram-negative coverage.
Minocycline is a broad-spectrum tetracycline antibiotic with a broader spectrum than other tetracyclines. It has a long half-life, resulting in higher serum levels than simple tetracyclines. Minocycline is highly lipid-soluble and penetrates tissues well but can cause more central nervous system side effects. Common uses include treating acne, skin infections, Lyme disease, and asthma. Potential side effects range from mild gastrointestinal issues to more serious allergic reactions and neuropsychiatric effects.
This document provides an overview of the antifungal drug amphotericin B, including its mechanism of action, antifungal spectrum, resistance, administration and dosing, pharmacokinetics, side effects, therapeutic uses, and adverse effects. It first introduces systemic fungal infections and the cellular structure and classification of fungi. It then focuses on describing in depth the mechanism by which amphotericin B acts, its antifungal effects, potential resistance issues, typical dosing and administration, pharmacokinetics, common side effects, therapeutic uses for treating fungal infections, and possible adverse effects.
Molecular mechanisms of action of bacteriophages.Dmitri Popov
The document discusses the lysogenic and lytic cycles of bacteriophages. It describes how the lysogenic cycle involves the integration of bacteriophage nucleic acid into the host bacterium's genome, allowing the genetic material to replicate with the host cell. The lytic cycle causes the virus to take over the host's DNA to produce viral proteins and particles, ultimately lysing the host cell. Both cycles can occur in bacteria and eukaryotes. The document also discusses prophages, lysogeny induction, and references several papers on bacteriophage therapy and resistance mechanisms.
In here I am talking about Amainoglycosides, its classification, mechanism of action, adverse effect, clinical uses of aminoglycoside, Pharmacokinetics..
This document discusses beta-lactamase inhibitors which are used to combat bacteria that have developed resistance to beta-lactam antibiotics like penicillins and cephalosporins. It explains that beta-lactamase enzymes produced by bacteria inactivate beta-lactam antibiotics by breaking the beta-lactam ring. The three main inhibitors discussed are clavulanic acid, sulbactam, and tazobactam, which are commonly used in combination with other antibiotics. Clavulanic acid is well-absorbed orally and re-establishes activity against common resistant bacteria. Sulbactam has less potency than clavulanic acid and is preferably given parenter
Study Material for Applications of Stem Cells In Health CareVamsi kumar
Explore the cutting-edge field of stem cell therapies and their pivotal role in treating autoimmune disorders with our comprehensive textbook. This essential resource covers the latest advances in the use of stem cells, including mesenchymal stem cells, induced pluripotent stem cells, and hematopoietic stem cell transplantation, in managing conditions such as rheumatoid arthritis, multiple sclerosis, type 1 diabetes, and systemic lupus erythematosus. Gain insights into innovative treatments, ethical considerations, and case studies showcasing successful patient outcomes. Whether you're a medical lab technology student, researcher, or healthcare professional, this textbook equips you with the knowledge and expertise to navigate the exciting world of stem cell-based therapies for autoimmune disorders.
By Atuluri Vamsi Kumar
Future of Embryology by Attuluri Vamsi KumarVamsi kumar
This comprehensive PowerPoint presentation offers a detailed exploration of the dynamic field of embryology and its significant role in medical science. Titled "Navigating the Future of Embryology: Innovations and Ethical Considerations," it delves into the history, current practices, and future prospects of embryology. It covers the evolution of embryological studies, the vital role of the Indian Council of Medical Research (ICMR) in shaping guidelines, and the impact of technological advancements on the discipline. With a focus on predictions and trends, the presentation also contemplates potential future amendments to guidelines in response to evolving technologies and ethical considerations. This resource is invaluable for medical professionals, researchers, and students keen on understanding the trajectory of embryology and its implications for future medical practices.
Cell wall inhibitors like β-lactam antibiotics inhibit the final step of bacterial cell wall synthesis. The penicillins interfere with transpeptidation by binding to penicillin-binding proteins. This prevents cross-linking of peptidoglycan chains, weakening the cell wall. Extended-spectrum penicillins are effective against gram-positive and some gram-negative bacteria but resistance has increased. Adverse effects include hypersensitivity reactions, diarrhea, and nephritis, particularly with methicillin which is no longer used.
This document discusses quinolones, a class of synthetic antimicrobial compounds. It begins by introducing nalidixic acid, the first quinolone, and how later fluorination led to more potent fluoroquinolone derivatives. Mechanism of action is described as inhibition of bacterial DNA gyrase and topoisomerase, preventing DNA replication. Adverse effects include tendonitis, CNS effects, and QT prolongation with some agents. Therapeutic uses include urinary tract infections, gonorrhea, respiratory infections, and more. Resistance develops via mutations impairing drug binding or drug efflux.
This document provides an overview of fungi. It discusses that fungi are eukaryotic organisms classified in the kingdom Fungi. They can exist as molds, yeasts, or dimorphic fungi. Fungi have cell walls containing chitin and reproduce asexually through spores or budding or sexually through the fusion of hyphae. The document outlines the morphological characteristics, differences from bacteria, classification systems based on cell structure and reproduction, and types of fungal infections like superficial, cutaneous, subcutaneous, and systemic mycoses.
Ciprofloxacin is a synthetic broad spectrum fluoroquinolone antibiotic that binds to and inhibits bacterial DNA gyrase, an enzyme essential for DNA replication. It is more active against Gram-negative bacteria. Ciprofloxacin lactate is manufactured by condensing Fluoroquinolonic Acid with piperazine and other compounds, then treating it with lactic acid to form Ciprofloxacin Lactate. The global market for ciprofloxacin hcl is growing due to its increasing use to treat infections in the urogenital, respiratory, and gastrointestinal systems as well as typhoid, bone and joint infections, and more.
This document discusses antibiotics and their properties. It describes how antibiotics are chemical substances produced by microorganisms that kill or inhibit pathogenic bacteria without harming host tissue. An ideal antibiotic should have broad-spectrum activity, be effective at low concentrations, kill bacteria rather than just inhibiting growth, selectively target pathogens, and not induce bacterial resistance. The document then discusses specific classes of antibiotics like tetracyclines, penicillins, and cephalosporins, outlining their mechanisms of action, properties, uses, and mechanisms of resistance.
This document provides information about virus structure and classification. It begins with the history of virology and defines viruses. It describes the differences between bacteria and viruses, and between DNA and RNA viruses. It outlines the characteristics, structure, replication process, and reaction to physical and chemical agents of viruses. It discusses viral morphology, classification based on shape and presence of an envelope. It also covers bacteriophage structure and important human viruses classified by genome type and associated disease.
Antibacterials and their mode of actionMidhun M Nair
This document discusses the history and classification of antibacterial agents. It begins by defining an antibacterial as an agent that interferes with bacterial growth and reproduction. It then provides a brief history of antibacterial use dating back to ancient Egypt and Greece. The document outlines several important discoveries and individuals that advanced the field, such as Alexander Fleming, Florey, Chain, and Selman Waksman. It proceeds to classify antibacterials according to their spectrum of activity (broad vs narrow), effect on bacteria (bactericidal vs bacteriostatic), and mode of action (inhibiting cell wall, membrane, protein, nucleic acid synthesis etc.). The classifications and examples are described in detail in the document.
This document discusses antigens and epitopes. It defines antigens as substances that induce an immune response and react with immune system products. Antigens include molecules like proteins, polysaccharides, and lipids. Epitopes are specific regions of antigens that interact with antibodies. A single antigen can have multiple epitopes that each bind to a different antibody. Factors that determine antigenicity include size, chemical nature, complexity, structural stability, foreignness, and an individual's genetic makeup.
1) Antibacterial agents, also known as antibiotics, are used to inhibit bacterial growth or kill bacteria. They are commonly classified based on their chemical origin or biological effect.
2) Antibacterial agents work by targeting differences between bacterial and animal cells, interfering with bacterial cell wall synthesis, protein synthesis, nucleic acid synthesis, or folic acid synthesis.
3) Common mechanisms of resistance include enzymatic modification of the antibacterial agent, mutations that prevent binding, or active efflux of the agent from the bacterial cell.
The document discusses antimicrobial agents and mechanisms of resistance. It covers several topics:
1. Definitions and classifications of antibiotics based on chemical structure, source, mechanism of action, and spectrum.
2. Mechanisms of antibiotic resistance in bacteria including production of enzymes to destroy drugs and genetic/non-genetic resistance.
3. Approaches to address rising antibiotic resistance such as appropriate use and preventing overprescription.
The document discusses the classification and development of quinolone drugs. It notes that first generation drugs like nalidixic acid had minimal serum levels, while second generation drugs like ciprofloxacin had increased gram-negative and systemic activity. Third generation drugs like levofloxacin expanded activity to gram-positive bacteria and atypical pathogens. Fourth generation drugs like trovafloxacin added significant activity against anaerobes. Newer fluoroquinolones have broad-spectrum bactericidal activity and good safety profiles.
Fungi reproduce through three main methods: vegetative reproduction through fragmentation or budding, asexual reproduction through spores produced on specialized structures, and sexual reproduction through the fusion of haploid gametes. Asexual reproduction can be endogenous through spores produced inside sporangia or exogenous through spores (conidia) produced on conidiophores. During sexual reproduction, haploid gametes from two parents fuse and undergo meiosis to produce diploid spores, restoring the haploid phase.
Anti protozoal and anti malarial drugsThiru Vinoth
Metronidazole is the prototype nitroimidazole anti-protozoal drug used to treat amoebiasis and other anaerobic bacterial infections. It is well absorbed orally and widely distributed throughout the body, with an elimination half-life of around 8 hours. Metronidazole's mechanism of action involves reduction of its nitro group by redox proteins in anaerobic organisms, which disrupts their energy metabolism. It is generally well tolerated but can cause adverse effects like nausea, metallic taste, and peripheral neuropathy with prolonged use. Metronidazole interacts with alcohol and some other drugs due to its metabolism.
Cephalosporins are a class of β-lactam antibiotics derived from fungi. They are classified into generations based on their spectrum of activity, with later generations having broader spectra. They work by binding penicillin-binding proteins. Resistance can develop via target modification or β-lactamase production. Newer generations have activity against MRSA and expanded gram-negative coverage.
Minocycline is a broad-spectrum tetracycline antibiotic with a broader spectrum than other tetracyclines. It has a long half-life, resulting in higher serum levels than simple tetracyclines. Minocycline is highly lipid-soluble and penetrates tissues well but can cause more central nervous system side effects. Common uses include treating acne, skin infections, Lyme disease, and asthma. Potential side effects range from mild gastrointestinal issues to more serious allergic reactions and neuropsychiatric effects.
This document provides an overview of the antifungal drug amphotericin B, including its mechanism of action, antifungal spectrum, resistance, administration and dosing, pharmacokinetics, side effects, therapeutic uses, and adverse effects. It first introduces systemic fungal infections and the cellular structure and classification of fungi. It then focuses on describing in depth the mechanism by which amphotericin B acts, its antifungal effects, potential resistance issues, typical dosing and administration, pharmacokinetics, common side effects, therapeutic uses for treating fungal infections, and possible adverse effects.
Molecular mechanisms of action of bacteriophages.Dmitri Popov
The document discusses the lysogenic and lytic cycles of bacteriophages. It describes how the lysogenic cycle involves the integration of bacteriophage nucleic acid into the host bacterium's genome, allowing the genetic material to replicate with the host cell. The lytic cycle causes the virus to take over the host's DNA to produce viral proteins and particles, ultimately lysing the host cell. Both cycles can occur in bacteria and eukaryotes. The document also discusses prophages, lysogeny induction, and references several papers on bacteriophage therapy and resistance mechanisms.
In here I am talking about Amainoglycosides, its classification, mechanism of action, adverse effect, clinical uses of aminoglycoside, Pharmacokinetics..
This document discusses beta-lactamase inhibitors which are used to combat bacteria that have developed resistance to beta-lactam antibiotics like penicillins and cephalosporins. It explains that beta-lactamase enzymes produced by bacteria inactivate beta-lactam antibiotics by breaking the beta-lactam ring. The three main inhibitors discussed are clavulanic acid, sulbactam, and tazobactam, which are commonly used in combination with other antibiotics. Clavulanic acid is well-absorbed orally and re-establishes activity against common resistant bacteria. Sulbactam has less potency than clavulanic acid and is preferably given parenter
Study Material for Applications of Stem Cells In Health CareVamsi kumar
Explore the cutting-edge field of stem cell therapies and their pivotal role in treating autoimmune disorders with our comprehensive textbook. This essential resource covers the latest advances in the use of stem cells, including mesenchymal stem cells, induced pluripotent stem cells, and hematopoietic stem cell transplantation, in managing conditions such as rheumatoid arthritis, multiple sclerosis, type 1 diabetes, and systemic lupus erythematosus. Gain insights into innovative treatments, ethical considerations, and case studies showcasing successful patient outcomes. Whether you're a medical lab technology student, researcher, or healthcare professional, this textbook equips you with the knowledge and expertise to navigate the exciting world of stem cell-based therapies for autoimmune disorders.
By Atuluri Vamsi Kumar
Future of Embryology by Attuluri Vamsi KumarVamsi kumar
This comprehensive PowerPoint presentation offers a detailed exploration of the dynamic field of embryology and its significant role in medical science. Titled "Navigating the Future of Embryology: Innovations and Ethical Considerations," it delves into the history, current practices, and future prospects of embryology. It covers the evolution of embryological studies, the vital role of the Indian Council of Medical Research (ICMR) in shaping guidelines, and the impact of technological advancements on the discipline. With a focus on predictions and trends, the presentation also contemplates potential future amendments to guidelines in response to evolving technologies and ethical considerations. This resource is invaluable for medical professionals, researchers, and students keen on understanding the trajectory of embryology and its implications for future medical practices.
I am Attuluri Vamsi Kumar, Academician in Medical Laboratory Sciences of highly successful job experience and a strong desire to improve OBE structured MLT education. I am constantly focusing on building an academic atmosphere that is set high standards with strong multi blended teaching pedagogy models. Contact me at 7416660584.
Notes of Shape and Size of RBCs, Structure of RBCs, Life Cycle of RBCs, Funct...Vamsi kumar
Red Blood Cells (RBCs) possess unique attributes essential for their function in the circulatory system. Their distinctive biconcave shape maximizes surface area for efficient gas exchange. Structurally, mature RBCs lack a nucleus, making room for hemoglobin, a molecule vital for oxygen and carbon dioxide transport. These cells undergo a lifecycle that lasts about 120 days, originating from the bone marrow and eventually being removed by the spleen. Their primary role involves ferrying oxygen to body tissues and removing carbon dioxide. Additionally, changes in RBC size, shape, or hemoglobin content can signify various medical conditions, and there are specific disorders, like anemia or sickle cell disease, that directly impact RBCs.
What is Medical Lab Technology, Difference between Treatment, Prognosis and Diagnosis, Role of Doctor or Physician and Medical Lab Technologist, Vital Signs, Significance of Vital Signs Assessment, Difference Between Signs and Symptoms in Patient Assessment, Example Case Study on Signs and Symptoms, Definition of Disease, Definition of Illness, Definition of Infection, Factors Contributing to Disease, Introduction to Factors Contributing to Disease, Types of Samples that Can be Collected from Patients for Clinical Diagnosis, Additional Types of Samples for Clinical Diagnosis.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
Welcome to the Hematology Laboratory Practical Manual, an essential tool in your journey as a Medical Laboratory Technology student. This manual has been meticulously curated to provide an effective foundation for your practical skills in hematology and enhance your understanding of the human blood system's dynamics.
Hematology, a branch of medicine, focuses on the study of blood, blood-forming organs, and blood diseases. It includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases. The manual bridges the gap between theoretical knowledge and practical application, intending to prepare you to perform and interpret various laboratory tests related to blood.
The manual introduces you to laboratory practices, standard operating procedures, and safety protocols. It explores a wide range of topics from the basic blood collection techniques, preparation of blood smears, and staining techniques to complex tests like complete blood count (CBC), coagulation tests, bone marrow examination, hemoglobinopathies, and blood group typing, to name a few.
Understanding the principles and methods used in hematology laboratory tests is crucial for any Medical Laboratory Technologist (MLT). You will find this manual to be instrumental in developing the necessary skillset and cultivating the meticulous approach required in laboratory practice. Each practical in this manual is supplemented with objectives, materials required, procedures, observations, precautions, and viva questions to enrich your learning experience.
The laboratory is a place where the theories you learn in the classroom come alive. Here, you will understand the importance of accuracy, precision, and repeatability. You will learn to calibrate equipment, handle samples, observe reactions, record data, analyze results, and generate reports. You will become acquainted with the microscope, centrifuge, pipettes, hemocytometers, reagents, and other laboratory tools.
To further enhance your learning experience, case studies and clinical correlation sections are incorporated, connecting the dots between laboratory findings and clinical symptoms. You will be challenged to interpret results and provide a plausible explanation for various hematological conditions.
This manual is designed to stimulate your curiosity, encourage critical thinking, and prepare you for your future role as a Medical Laboratory Technologist. It is not merely a collection of laboratory procedures but a practical guide to understanding the human blood system and its associated disorders.
The path to becoming a competent MLT involves understanding and respecting the significance of laboratory practices. It's about knowing that each sample represents a person awaiting diagnosis, treatment, or confirmation of health stat
This course provides an in-depth exploration of blood bank laboratory practices and procedures, introducing students to the core concepts and technical skills involved in blood banking. The program uses a case-based approach to facilitate the application of theoretical knowledge to practical scenarios, encouraging problem-solving skills and clinical reasoning. The curriculum spans from basic principles and safety considerations to advanced testing techniques and current trends in blood banking, providing comprehensive coverage of this essential area of medical lab technology.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This course provides an extensive study of research methodologies in the field of Medical Lab Technology. Students will learn the fundamentals of research, how to design their research, and methods of data collection. Further, they will gain insights into data analysis, interpretation of results, and the essentials of writing a research report. The course integrates theoretical learning with practical case studies to facilitate a comprehensive understanding of the subject.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
51_Introduction to Artificial Intelligence and its applications.pdfVamsi kumar
This course provides an in-depth understanding of the fundamentals, applications, and future trends of artificial intelligence (AI) in the field of medical lab technology. It covers the role of AI in clinical lab diagnostics, predictive analysis, big data interpretation, precision medicine, and ethical considerations in AI deployment. Through case studies, students will gain practical insights into the use of AI in healthcare.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This Medical Lab Technology Internship syllabus is intended to provide students with the opportunity to apply and enhance their knowledge and skills in the context of real-world laboratory settings. Over the course of six months, interns will gain hands-on experience in essential and advanced laboratory techniques, laboratory safety practices, quality assurance processes, and professional and ethical considerations in the field. Through practical learning and critical examination of case studies, students will emerge better prepared for their careers as Medical Lab Technologists.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This course aims to provide students with an in-depth understanding of blood banking, including the concepts of blood grouping, compatibility testing for transfusion, and the management of blood resources. It also delves into the fundamental principles of genetics, focusing on inheritance patterns, chromosomal basis of inheritance, and the role of DNA and RNA in protein synthesis. Through practical exercises, students will gain hands-on experience on various techniques used in blood banking and genetics.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This course in "Virology and Mycology" (701) is designed to provide a comprehensive understanding of the medically important fungi and viruses. The content includes an introduction, general characteristics, life cycle, laboratory diagnosis, and the various techniques used in the identification and study of these microbes. This course will also equip students with practical skills, from preparing culture media to processing clinical samples for diagnosis.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
50_Research methodology and Biostatistics.pdfVamsi kumar
This syllabus covers the foundational aspects of Research Methodology and Biostatistics. The course is designed to equip students with the necessary understanding and skills to formulate research problems, address ethical considerations, design research studies, comprehend the basic concepts of Biostatistics, and understand the relationship between data and variables. The aim is to enhance the students' ability to construct, summarize, and analyze data in biostatistics effectively.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This course is designed to provide Medical Lab Technology students with a comprehensive understanding of the medical microbiology laboratory's operation. It starts with foundational knowledge in laboratory safety, equipment, and microbial classification and then advances to diagnostic microbiology techniques, immunology, and serology. Lastly, it explores more sophisticated lab procedures such as molecular diagnostics, virology, and recent trends in the field. Each unit comes with real-life case studies to further reinforce the application of theoretical knowledge.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
44_Program Elective course - III (Introduction to NABL).pdfVamsi kumar
This course provides an in-depth understanding of the National Accreditation Board for Testing and Calibration Laboratories (NABL) accreditation process, its quality management system (QMS), and the practical aspects of implementing the NABL standards. The course includes an analysis of case studies to enhance the understanding of real-world applications of the NABL accreditation process.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
49_Immunopathology and Molecular Biology.pdfVamsi kumar
This course aims to provide students with an in-depth understanding of Immunopathology and Molecular Biology, with a focus on the immune system's role in health and disease, transplantation immunology, hypersensitivity, autoimmunity, and immune tolerance. Additionally, it introduces molecular biology, DNA structure, and replication, with practical applications of molecular techniques such as PCR, gel electrophoresis, and western blotting.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This course, Applied Clinical Biochemistry- II, is designed to impart in-depth knowledge about the techniques and methods used in clinical biochemistry. The curriculum focuses on automation in clinical biochemistry, methods of estimation and assessment, enzyme principles and estimation, gastric analysis, renal function tests, qualitative tests, and chemical examination. The students will engage in practical applications of these concepts through hands-on experimentation.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
45_Program Elective course - III (Laboratory and Hospital information syste...Vamsi kumar
The elective course "Hospital Information System and Laboratory Information System" aims to provide medical lab technology students with a comprehensive understanding of the design, implementation, and usage of health and laboratory information systems in the healthcare sector. It emphasizes the significance of these systems in ensuring effective patient care, data interoperability, and the integration of various systems for optimized healthcare delivery.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
43_Program Elective course - III (Community medicine).pdfVamsi kumar
This syllabus covers the principles and applications of Community Medicine and Epidemiology. Students will gain a comprehensive understanding of community health, disease control, health promotion, and the role of medical social work. They will apply knowledge to real-world case studies, fostering skills in critical analysis, problem-solving, and ethical decision-making.
Created by: Mr. Attuluri Vamsi Kumar, Assistant Professor, Department of MLT, UIAHS, Chandigarh University, Mohali, Punjab. For more details website: https://www.mltmaster.com
This course aims to provide a comprehensive understanding of the field of Cytopathology. It begins with the basics of cryostat sectioning and enzyme cytochemistry, proceeding towards an in-depth study of cytological investigations, including vital staining and aspiration cytology. The course then focuses on advanced topics like exfoliative cytology, automation in cytology, liquid-based cytology, and immune-cytochemistry. Finally, it allows students to apply their theoretical knowledge to practical applications and master various techniques and staining methods used in a Cytology lab.
How to Add Chatter in the odoo 17 ERP ModuleCeline George
In Odoo, the chatter is like a chat tool that helps you work together on records. You can leave notes and track things, making it easier to talk with your team and partners. Inside chatter, all communication history, activity, and changes will be displayed.
Strategies for Effective Upskilling is a presentation by Chinwendu Peace in a Your Skill Boost Masterclass organisation by the Excellence Foundation for South Sudan on 08th and 09th June 2024 from 1 PM to 3 PM on each day.
This presentation was provided by Steph Pollock of The American Psychological Association’s Journals Program, and Damita Snow, of The American Society of Civil Engineers (ASCE), for the initial session of NISO's 2024 Training Series "DEIA in the Scholarly Landscape." Session One: 'Setting Expectations: a DEIA Primer,' was held June 6, 2024.
How to Build a Module in Odoo 17 Using the Scaffold MethodCeline George
Odoo provides an option for creating a module by using a single line command. By using this command the user can make a whole structure of a module. It is very easy for a beginner to make a module. There is no need to make each file manually. This slide will show how to create a module using the scaffold method.
Exploiting Artificial Intelligence for Empowering Researchers and Faculty, In...Dr. Vinod Kumar Kanvaria
Exploiting Artificial Intelligence for Empowering Researchers and Faculty,
International FDP on Fundamentals of Research in Social Sciences
at Integral University, Lucknow, 06.06.2024
By Dr. Vinod Kumar Kanvaria
This presentation includes basic of PCOS their pathology and treatment and also Ayurveda correlation of PCOS and Ayurvedic line of treatment mentioned in classics.
Leveraging Generative AI to Drive Nonprofit InnovationTechSoup
In this webinar, participants learned how to utilize Generative AI to streamline operations and elevate member engagement. Amazon Web Service experts provided a customer specific use cases and dived into low/no-code tools that are quick and easy to deploy through Amazon Web Service (AWS.)
How to Setup Warehouse & Location in Odoo 17 InventoryCeline George
In this slide, we'll explore how to set up warehouses and locations in Odoo 17 Inventory. This will help us manage our stock effectively, track inventory levels, and streamline warehouse operations.
How to Fix the Import Error in the Odoo 17Celine George
An import error occurs when a program fails to import a module or library, disrupting its execution. In languages like Python, this issue arises when the specified module cannot be found or accessed, hindering the program's functionality. Resolving import errors is crucial for maintaining smooth software operation and uninterrupted development processes.