PH ppt monophasicliquiddosagefrom.pptx
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This document discusses monophasic liquids and their advantages and disadvantages as drug delivery systems. It provides examples of different types of monophasic liquids including syrups, elixirs, gargles, and mouthwashes. Syrups can be simple (containing 66.7% w/w sugar) or flavored. Elixirs contain 5-40% alcohol as a preservative. The document also notes some challenges with monophasic liquids like their bulkiness and potential for microbial growth or drug degradation.
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Monophasic liquid dosage form B.Pharmacy 1st Sem PTU by pankaj kumar maurya
The document discusses monophasic liquid dosage forms, which are clear, homogeneous mixtures containing two or more components dissolved in a single phase. It classifies monophasic liquids based on their route of administration, such as those for internal use like syrups, elixirs, and linctuses; those for topical use like gargles, mouthwashes, and throat paints; and those for instillation into body cavities like eye drops, nasal drops, and enemas. Preparations of various monophasic liquids are also described, including gargles, mouthwashes, elixirs, syrups, throat paints, lotions, ear drops, nasal drops, and liniments.
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This document provides information on various types of monophasic liquid dosage forms, including their definitions, advantages, disadvantages, examples, and typical formulation methods. It discusses gargles, mouthwashes, throat paints, ear drops, nasal drops, syrups, elixirs, liniments, and lotions. For each type, it provides a brief description of its use and purpose as well as an example formulation and method.
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Monophasic liquid dosage form B.Pharmacy 1st Sem PTU by pankaj kumar maurya
The document discusses monophasic liquid dosage forms, which are clear, homogeneous mixtures containing two or more components dissolved in a single phase. It classifies monophasic liquids based on their route of administration, such as those for internal use like syrups, elixirs, and linctuses; those for topical use like gargles, mouthwashes, and throat paints; and those for instillation into body cavities like eye drops, nasal drops, and enemas. Preparations of various monophasic liquids are also described, including gargles, mouthwashes, elixirs, syrups, throat paints, lotions, ear drops, nasal drops, and liniments.
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The document discusses various types of monophasic liquid dosage forms including solutions, gargles, mouthwashes, throat paints, ear drops, nasal drops and sprays, enemas, syrups, and elixirs. It provides details on the composition, uses, formulations, preparation methods, packaging, storage, and labeling of these different dosage forms. Monophasic liquid dosage forms consist of a single phase and are used for local effects in the mouth, ears, nose, or rectum or for systemic effects when taken orally or parenterally.
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Syrups are concentrated aqueous preparations of sugar or sugar substitute that may contain flavorings or medicinal substances. There are three main types of syrups: simple syrups containing only sugar and water, and non-medicated and medicated syrups which can also contain flavorings or therapeutic agents. Syrups are prepared through methods such as heating the sugar and water mixture, agitating the ingredients without heat, or adding sucrose to a flavored or medicated liquid. Proper packaging is required to ensure syrups remain free from contamination and microbial growth during their shelf life.
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2. Liquid dosage forms are classified as monophasic containing one phase like syrups, or biphasic containing two phases like suspensions and emulsions.
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A solution is a homogeneous mixture of a solute dissolved in a solvent. Solutions have several advantages including rapid absorption and easy administration. However, solutions also have short shelf lives and are prone to contamination. Aqueous solutions use water as the solvent while non-aqueous solutions use other solvents like oils, alcohols, or glycerol. Common oral solutions include syrups, elixirs, and linctuses. Other medical solutions include enemas, nasal drops, ear drops, mouthwashes, and gargles. Solutions are manufactured by dissolving the solute in solvent with agitation, optionally applying heat, then filtering the finished product.
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Liquid dosage forms include syrups, elixirs, tinctures, and other preparations meant for oral or other administration. Syrups are concentrated sugar solutions that can disguise bad tastes and soothe irritated tissues. Elixirs are clear, sweetened alcohol solutions that are less viscous than syrups. Tinctures are alcoholic or hydro-alcoholic solutions made by soaking plant or animal materials in alcohol or other solvents. Common liquid dosage forms are used to deliver medications locally or systemically for various conditions.
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This document provides an introduction to pharmaceutical dosage forms. It defines dosage forms as safe, effective, and stable means of delivering medication to the body, which typically include active drug components and excipients. Dosage forms are classified as solid, liquid, or semi-solid and by route of administration such as oral, topical, or parenteral. Common dosage forms described include tablets, capsules, ointments, creams, gels, and solutions. The document discusses characteristics and methods of preparation for different types of dosage forms.
Syrupnew1-140827141820-phpapp01.pptx
Syrup is a concentrated aqueous solution of sugar or a sugar substitute with flavoring and active pharmaceutical ingredients. It is a convenient oral liquid dosage form for children, elderly, and those who cannot swallow solid medications. Syrups are prepared through various methods including solution with heat, agitation without heat, addition of sucrose to liquid medications, or percolation. Key components of syrups include a sweetening agent, preservatives, viscosity modifiers, flavorants, and colorants. Syrups provide advantages like ease of administration but also have disadvantages like delayed drug absorption and inability to avoid first-pass metabolism.
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This document defines and describes syrups. Syrups are nearly saturated sugar solutions, often containing flavorings or medications. The key points are:
- Syrups use sucrose (table sugar) as the primary solute. The high sugar concentration prevents microbial growth.
- Preservatives may be needed if the syrup contains less than 85% sugar. Common preservatives include benzoic acid, sodium benzoate, and parabens.
- Sorbitol and artificial sweeteners can make non-nutritive syrups for people who need to limit sugar intake, like those with diabetes.
- Syrups are prepared by dissolving sugar in water with heat or agitation
Classical Dosage Forms
Classical dosage forms including Cachets, Lozenges, Tinctures and Snuffs. These 4 dosage forms are described undeer this presentation.
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Solutions are one of the oldest dosage forms used to treat patients by providing rapid absorption of soluble active ingredients. Solutions aim to dissolve ingredients uniformly in a suitable vehicle like water. Key considerations in preparing solutions are the solubility of active ingredients and the stability of the final formulation. Solutions can be prepared for oral, topical, or other routes of administration depending on the intended use and formulation.
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Monophasic dosage forms refer to liquid preparations containing components in a single phase system, represented by a true solution. A true solution is a homogeneous mixture prepared by dissolving a solute in a suitable solvent. Common monophasic dosage forms include aqueous solutions used as gargles, mouthwashes, and ear/nasal drops to treat infections locally. They allow for easier administration than solids and faster drug absorption but require preservatives due to the risk of microbial growth.
Copy of syrup annd elixers.pptx
Syrups are concentrated aqueous preparations of sugar or sugar substitute that may contain flavorings or medicinal substances. There are three main types of syrups: simple syrups containing only sugar and water, and non-medicated and medicated syrups which can also contain flavorings or therapeutic agents. Syrups are prepared through methods such as heating the sugar and water mixture, agitating the ingredients without heat, or adding sucrose to a flavored or medicated liquid. Proper packaging is required to ensure syrups remain free from contamination and microbial growth during their shelf life.
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This document discusses syrups and elixirs. It defines syrups as concentrated aqueous preparations containing sugar or sugar substitutes, with or without flavoring or medicinal agents. Simple syrup is defined as an 85% w/v sucrose solution. Methods of syrup preparation include solution with heat, agitation, addition of sucrose to medicated/flavored liquids, and percolation. Syrups provide benefits like disguising taste and soothing throat tissues. Elixirs are sweetened hydro-alcoholic solutions, usually flavored, containing 10-12% alcohol for preservation. They are easier to administer than solids but contain alcohol. Both syrups and elixirs require storage below 30°C in tight, light
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Liquid dosage form
1. The document discusses liquid dosage forms, which provide advantages over solid forms like faster absorption.
2. Liquid dosage forms are classified as monophasic containing one phase like syrups, or biphasic containing two phases like suspensions and emulsions.
3. Key liquid dosage forms are described including their composition, preparation, and uses both internally and externally. Advantages and disadvantages of liquid dosage forms are also outlined.
Solution
A solution is a homogeneous mixture of a solute dissolved in a solvent. Solutions have several advantages including rapid absorption and easy administration. However, solutions also have short shelf lives and are prone to contamination. Aqueous solutions use water as the solvent while non-aqueous solutions use other solvents like oils, alcohols, or glycerol. Common oral solutions include syrups, elixirs, and linctuses. Other medical solutions include enemas, nasal drops, ear drops, mouthwashes, and gargles. Solutions are manufactured by dissolving the solute in solvent with agitation, optionally applying heat, then filtering the finished product.
1. monophasic liquids naresh
This document provides an overview of monophasic liquid dosage forms, including their advantages, disadvantages, and classifications. It discusses formulation considerations such as solubility, stability, preservatives, and factors that enhance pharmaceutical elegance. Monophasic liquids are classified based on their route of administration, such as oral liquids like syrups, elixirs, and linctuses or external liquids like eye drops, nasal drops, and enemas. Key formulation aspects addressed include using pH adjustments, co-solvents, complexation, and micronization to improve drug solubility, as well as buffers, antioxidants, and packaging to ensure chemical stability.
Monophasic liquid dosage forms
This document discusses various types of monophasic liquid dosage forms including mixtures, syrups, elixirs, linctuses, and liquids that can be applied to the skin, used in the mouth, or instilled into body cavities. It provides details on the formulation, containers, labeling, and storage of these dosage forms.
Liquid dosage forms krishna
This document discusses liquid dosage forms, including their classification and composition. It begins by defining liquid dosage forms and describing their monophasic and biphasic forms. It then classifies common liquid dosage forms for internal and external use, such as syrups, elixirs, linctuses, drops, liniments, and lotions. The document describes the composition and preparation of various liquid dosage forms. It concludes by discussing the advantages and disadvantages of liquid dosage forms and describing common additives used in liquid formulations such as vehicles, buffers, and preservatives.
A view of pharmaceutical dosage forms
A brief description of pharmaceutical dosage forms and their route of administration and typical process flow and manufacturing details. It may help new aspirants who wnts to knoiw aboute dosageforms and their administration routes.
Liquid drug forms.pptx
Liquid dosage forms include syrups, elixirs, tinctures, and other preparations meant for oral or other administration. Syrups are concentrated sugar solutions that can disguise bad tastes and soothe irritated tissues. Elixirs are clear, sweetened alcohol solutions that are less viscous than syrups. Tinctures are alcoholic or hydro-alcoholic solutions made by soaking plant or animal materials in alcohol or other solvents. Common liquid dosage forms are used to deliver medications locally or systemically for various conditions.
Introduction of Dosage Form.pdf
This document provides an introduction to pharmaceutical dosage forms. It defines dosage forms as safe, effective, and stable means of delivering medication to the body, which typically include active drug components and excipients. Dosage forms are classified as solid, liquid, or semi-solid and by route of administration such as oral, topical, or parenteral. Common dosage forms described include tablets, capsules, ointments, creams, gels, and solutions. The document discusses characteristics and methods of preparation for different types of dosage forms.
Syrupnew1-140827141820-phpapp01.pptx
Syrup is a concentrated aqueous solution of sugar or a sugar substitute with flavoring and active pharmaceutical ingredients. It is a convenient oral liquid dosage form for children, elderly, and those who cannot swallow solid medications. Syrups are prepared through various methods including solution with heat, agitation without heat, addition of sucrose to liquid medications, or percolation. Key components of syrups include a sweetening agent, preservatives, viscosity modifiers, flavorants, and colorants. Syrups provide advantages like ease of administration but also have disadvantages like delayed drug absorption and inability to avoid first-pass metabolism.
SYRUP.pdf
This document defines and describes syrups. Syrups are nearly saturated sugar solutions, often containing flavorings or medications. The key points are:
- Syrups use sucrose (table sugar) as the primary solute. The high sugar concentration prevents microbial growth.
- Preservatives may be needed if the syrup contains less than 85% sugar. Common preservatives include benzoic acid, sodium benzoate, and parabens.
- Sorbitol and artificial sweeteners can make non-nutritive syrups for people who need to limit sugar intake, like those with diabetes.
- Syrups are prepared by dissolving sugar in water with heat or agitation
Classical Dosage Forms
Classical dosage forms including Cachets, Lozenges, Tinctures and Snuffs. These 4 dosage forms are described undeer this presentation.
Solutions
Solutions are one of the oldest dosage forms used to treat patients by providing rapid absorption of soluble active ingredients. Solutions aim to dissolve ingredients uniformly in a suitable vehicle like water. Key considerations in preparing solutions are the solubility of active ingredients and the stability of the final formulation. Solutions can be prepared for oral, topical, or other routes of administration depending on the intended use and formulation.
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PH ppt monophasicliquiddosagefrom.pptx
- 1. • MONOPHSIC LIQUIDS DOSAGE FROM • NAME: JUNED SAJEED SHAIKH, • ROLL NO.:79 • DIVISION :2nd • F.Y
- 4. INTRODUCTION
- 5. Advantage • It is easier to swallow, therefore easier for children and old age people. • Facilitate absorption of drug faster than solid dosage form as drug is already in solution form. • It is homogenous therefore give uniform dose than suspension or emulsion which need shaking. • Simple and fast to formulate • It can be administered by various routes : Oral, Parenteral (injection),enema for rectal use, otic(ear), nasal and ophthalmic preparation.
- 6. They are bulky, so difficult to transport and store. • Water is commonly use vehicle, which is prone to microbial growth. So addition of preservative is needed. • When expose to direct sunlight it may undergo hydrolysis, so need to store in cool and dark place. • Drug stability reduce by hydrolysis or oxidation. So, they have shorter expire date than solid dosage form. • Other major sign of drug instability are color change, Precipitation, microbial growth etc. DISADVANTAGE
- 8. Liquids meant for internal administrations SYRUPS ⚫ I.P contains 66.7% W/W in P.W (100ml) ⚫U.S.P contains 85% W/V in P.W (100ml) ⚫ Medicated Syrup: e.g Cough syrup ⚫ Flavoured Syrup: e.g Cheery syrup ⚫ Invert Syrup: according to BPC invert syrup is prepared by hydrolysing sucrose with HCL & solution neutralised with calcium or sodium carbonate. In invert syrup contains levulose, sucrose & dextrose in the ratio 173: 100:74 • The invert sugar is 1.23 times sweet as sucrose.
- 9. ELIXIRS ⚫ Alcohol content varies 5 to 40% 10 to 12% alcohol are stable preservative. & not required the METHOD OF FORMULATION Simple agitation method used Alcoholic soluble ingredients dissolve in alcohol. Water soluble ingredients dissolve in water. Then water solution mixed with alcoholic solution. If any oil ingredients added, then use with talc for removing of oil droplets & again filter it. e.g Paracetamol Elixir
- 12. Liquids meant for external administration Liquids used in the mouth • Gargles :Aqueous solution s containing antiseptics or antibiotics used to treat throat infections. Available in concentrated form with direction for dilution with warm water before use. eg: Povidone Iodine gargle. • Mouthwash: Aqueous solution with a pleasant taste and odor used to clean and deodorize the buccal cavity. Have antiseptic and astringent