Ben Page gave this presentation at the Department for Education National College for Training & School Leadership annual conference "Seizing Success 2013". More information: http://www.education.gov.uk/nationalcollege/index/events/conference2013/conference2013-ben-page-making-sense-of-britain.htm
Trends Shaping Education 2016 provides an overview of key economic, social, demographic and technological trends and raises pertinent questions about their potential impact on education. This compilation makes use of a variety of robust international sources of data, including the OECD, the World Bank and the United Nations.
How’s Life? 2015 describes the essential ingredients that shape people’s well-being in OECD and other major economies. It includes a wide variety of statistics, capturing both material well-being and quality of life. This third edition includes a special focus on child well-being, on volunteering and on inequalities in well-being across different regions within countries.
According to Ipsos MORI's latest Issues Index for The Economist, 36% of the public mention the economy amongst the most important issues facing Britain – a fall of three percentage points since last month, and the lowest percentage to do so since June 2008, as concern was increasing as a result of the financial crisis.
Business and Brexit: The risks of taking a stanceIpsos UK
British adults think that businesses should be involved in the EU referendum debate – but that doesn’t mean they will trust them. When asked whether different types of business should take part in the EU referendum campaign, support was high for British businesses to participate by publicly backing one side or the other, especially SMEs. However, this does not necessarily mean the public trust what big businesses say on the issues.
The new survey finds three-quarters (75%) of the public say that small and medium-size British businesses should participate in the debate – more than say the same for other groups such as academics (68%), think tanks (54%) and newspapers (52%). The contributions of SMEs are more welcome than those of big businesses – but still nearly seven in ten (69%) of British adults are happy for big British businesses which trade internationally to make their opinion on Brexit known. However, while three-fifths (57%) say that they trust small business owners on issues relating to the referendum, leaders of large businesses fare worse, being trusted on the issues by just three in ten (29%).
Ben Page gave this presentation at the Department for Education National College for Training & School Leadership annual conference "Seizing Success 2013". More information: http://www.education.gov.uk/nationalcollege/index/events/conference2013/conference2013-ben-page-making-sense-of-britain.htm
Trends Shaping Education 2016 provides an overview of key economic, social, demographic and technological trends and raises pertinent questions about their potential impact on education. This compilation makes use of a variety of robust international sources of data, including the OECD, the World Bank and the United Nations.
How’s Life? 2015 describes the essential ingredients that shape people’s well-being in OECD and other major economies. It includes a wide variety of statistics, capturing both material well-being and quality of life. This third edition includes a special focus on child well-being, on volunteering and on inequalities in well-being across different regions within countries.
According to Ipsos MORI's latest Issues Index for The Economist, 36% of the public mention the economy amongst the most important issues facing Britain – a fall of three percentage points since last month, and the lowest percentage to do so since June 2008, as concern was increasing as a result of the financial crisis.
Business and Brexit: The risks of taking a stanceIpsos UK
British adults think that businesses should be involved in the EU referendum debate – but that doesn’t mean they will trust them. When asked whether different types of business should take part in the EU referendum campaign, support was high for British businesses to participate by publicly backing one side or the other, especially SMEs. However, this does not necessarily mean the public trust what big businesses say on the issues.
The new survey finds three-quarters (75%) of the public say that small and medium-size British businesses should participate in the debate – more than say the same for other groups such as academics (68%), think tanks (54%) and newspapers (52%). The contributions of SMEs are more welcome than those of big businesses – but still nearly seven in ten (69%) of British adults are happy for big British businesses which trade internationally to make their opinion on Brexit known. However, while three-fifths (57%) say that they trust small business owners on issues relating to the referendum, leaders of large businesses fare worse, being trusted on the issues by just three in ten (29%).
Legal trends in Europe towards increasing female inclusivity in Boards in Europe, and diversity strategies make us wonder about the real impact on the firm performance. This project presentation is the initial analysis of a longer work, were although we see a correlation at a certain number of female board members and profitability, we can not state a causality. Moreover, some metrics and impacts in strategic changes could come more in the long term. Emphasis on slide 9. UofSC Spring 2019
Ipsos Global @dvisor Wave 44: Corporate Social ResponsibilityIpsos UK
Four in ten (37%) employees in 24 countries indicate it is ‘very important’ for their own employers to be ‘responsible to society and the environment’ This importance rises to 80% when it is combined with those employees who believe it is somewhat important (37% very/43% somewhat) their employer is responsible. Three in ten (29%) report ‘a high degree of social responsibility’ is very important when forming a purchase decision while about half (45%) view it as fairly important for a total of 74% who say it is important.
Ipsos MORI Issues Index: 2017 Year in ReviewIpsos UK
The NHS and Brext replaced immigration as the biggest issue facing Britain across the whole of 2017.
Across 2017 the biggest issue facing Britain was the NHS, mentioned by nearly half of the public (48%)
Concern about Brexit was in very close second place (46%), and was the biggest single issue of the year
Worry with immigration fell notably; one quarter (26%) of the public mentioned it as an issue in 2017, compared with 40% in 2016
Craft Scotland Makers Survey 2013 – the results.
In May Craft Scotland initiated a survey, developed and managed by The Audience Business (TAB), to measure a number of factors which we believe are important to building and maintaining a thriving craft sector. These include:
• Stronger craft networks
• A more confident sector
• Improved exchange of information, on and offline
• Better sector engagement with public bodies
• Improved public engagement with craft
• Better access to new audiences and markets
• Improved marketing skills in the sector
• Increased profile for the sector
The Case Study (elaborated solely by AIEC) describes the topic of the Job tendencies and vocational orientation and guidance in the ICT sector. Due to the topic of the Youth4Job project, special focus of the study is given to the youth population.
The Women And Work Commission found that unleashing women’s full potential could be worth £23 billion a year to the Exchequer. To put this into context, this year’s central government budget for Education is £28.6 billion.
Visit - www.ProcurementCentral.com
After reaching a record level of concern in July following Britain’s decision to leave the EU, fewer Britons now show concern about the EU, according to Ipsos MORI’s August Issues Index. Three in ten (31%) now say they are concerned about the EU – down 9 points from July – although it is still seen as the single most important issue (mentioned by 21% as their most concerning issue).
This month the Ipsos MORI/Economist Issues Index shows there has been a leap in public concern about the NHS, with 40% seeing it as a big issue facing the country, up nine percentage points from August and the highest score since June 2015. Having said that, only 10% see it as the biggest single issue facing the country. Fieldwork began just before the cancellation of the September Junior Doctors’ strike, scheduled for the 12th – 16th September.
Helen Wilson, Managing Director, Ipsos Loyalty - the Customer Experience Specialists - presented at Mayfair Capital’s excellent Investment Seminar this week. For more visit http://www.mayfaircapital.co.uk/. Our Perils of Perception research is at https://www.ipsos-mori.com/_assets/sri/perils/. For more on our research into Generations, visit www.ipsos-mori-generations.com.
The Department for Business, Innovation and Skills commissioned Ipsos MORI to conduct a survey into UK attitudes to ethical standards in retail and their impact on the public’s buying decisions.
PowerPoint by Ms. Gabriela Ramos, OECD Chief of Staff, G20 Sherpa, and Special Counsellor to the Secretary-General, Skills Summit 2018, Porto.
SSESSION 1: UNDERSTAND – Risks and opportunities in a digital world: the changing landscape of skills needs
Objective: Build a common understanding of how the digital revolution transforms economies and societies, how the skills that people need in everyday life and in the workplace are changing, and which groups of the population are most at risk of being left behind
Legal trends in Europe towards increasing female inclusivity in Boards in Europe, and diversity strategies make us wonder about the real impact on the firm performance. This project presentation is the initial analysis of a longer work, were although we see a correlation at a certain number of female board members and profitability, we can not state a causality. Moreover, some metrics and impacts in strategic changes could come more in the long term. Emphasis on slide 9. UofSC Spring 2019
Ipsos Global @dvisor Wave 44: Corporate Social ResponsibilityIpsos UK
Four in ten (37%) employees in 24 countries indicate it is ‘very important’ for their own employers to be ‘responsible to society and the environment’ This importance rises to 80% when it is combined with those employees who believe it is somewhat important (37% very/43% somewhat) their employer is responsible. Three in ten (29%) report ‘a high degree of social responsibility’ is very important when forming a purchase decision while about half (45%) view it as fairly important for a total of 74% who say it is important.
Ipsos MORI Issues Index: 2017 Year in ReviewIpsos UK
The NHS and Brext replaced immigration as the biggest issue facing Britain across the whole of 2017.
Across 2017 the biggest issue facing Britain was the NHS, mentioned by nearly half of the public (48%)
Concern about Brexit was in very close second place (46%), and was the biggest single issue of the year
Worry with immigration fell notably; one quarter (26%) of the public mentioned it as an issue in 2017, compared with 40% in 2016
Craft Scotland Makers Survey 2013 – the results.
In May Craft Scotland initiated a survey, developed and managed by The Audience Business (TAB), to measure a number of factors which we believe are important to building and maintaining a thriving craft sector. These include:
• Stronger craft networks
• A more confident sector
• Improved exchange of information, on and offline
• Better sector engagement with public bodies
• Improved public engagement with craft
• Better access to new audiences and markets
• Improved marketing skills in the sector
• Increased profile for the sector
The Case Study (elaborated solely by AIEC) describes the topic of the Job tendencies and vocational orientation and guidance in the ICT sector. Due to the topic of the Youth4Job project, special focus of the study is given to the youth population.
The Women And Work Commission found that unleashing women’s full potential could be worth £23 billion a year to the Exchequer. To put this into context, this year’s central government budget for Education is £28.6 billion.
Visit - www.ProcurementCentral.com
After reaching a record level of concern in July following Britain’s decision to leave the EU, fewer Britons now show concern about the EU, according to Ipsos MORI’s August Issues Index. Three in ten (31%) now say they are concerned about the EU – down 9 points from July – although it is still seen as the single most important issue (mentioned by 21% as their most concerning issue).
This month the Ipsos MORI/Economist Issues Index shows there has been a leap in public concern about the NHS, with 40% seeing it as a big issue facing the country, up nine percentage points from August and the highest score since June 2015. Having said that, only 10% see it as the biggest single issue facing the country. Fieldwork began just before the cancellation of the September Junior Doctors’ strike, scheduled for the 12th – 16th September.
Helen Wilson, Managing Director, Ipsos Loyalty - the Customer Experience Specialists - presented at Mayfair Capital’s excellent Investment Seminar this week. For more visit http://www.mayfaircapital.co.uk/. Our Perils of Perception research is at https://www.ipsos-mori.com/_assets/sri/perils/. For more on our research into Generations, visit www.ipsos-mori-generations.com.
The Department for Business, Innovation and Skills commissioned Ipsos MORI to conduct a survey into UK attitudes to ethical standards in retail and their impact on the public’s buying decisions.
PowerPoint by Ms. Gabriela Ramos, OECD Chief of Staff, G20 Sherpa, and Special Counsellor to the Secretary-General, Skills Summit 2018, Porto.
SSESSION 1: UNDERSTAND – Risks and opportunities in a digital world: the changing landscape of skills needs
Objective: Build a common understanding of how the digital revolution transforms economies and societies, how the skills that people need in everyday life and in the workplace are changing, and which groups of the population are most at risk of being left behind
Skilled for Life - Presentation by Andreas Schleicher at the PIAAC Internatio...EduSkills OECD
The purpose of the second PIAAC International Conference 2015 is to present work using data from the Programme for the International Assessment of Adult Competencies (PIAAC) relating to issues such as: the deployment of skills in the economy, returns to education and skills or the influence of workplace training.
A broken social elevator? How to promote social mobility.
Presentation by Stefano Scarpetta, Director for Employment, Labour and Social Affairs, OECD
Webinar 15 June 2018.
Latvijas ekonomiskā situācija, darba tirgus un prognozesLatvijas Banka
Latvijas Bankas ekonomista Oļega Krasnopjorova prezentācija, kas izmantota 2019. gada 23. maijā Rīgā notikušā starptautiskā seminārā par darba tirgus izaicinājumiem.
Education at a Glance Interim Report:Update of Employment and Educational Att...EduSkills OECD
The social consequences of the crisis were still deepening in 2013, especially among the most vulnerable groups such as low-educated young adults. In most OECD countries more than four out of five younger adults have attained at least an upper secondary education, implying that one in six of them have qualifications below upper secondary education.
This presentation provides an overview of worker participation in the prevention of MSDs and steps that employers can take to actively involve workers in identifying musculoskeletal problems and choosing and implementing the best solutions
A Workers’ Survey on Exposure to Cancer Risk Factors in Europe: An Innovative Approach to get Comparable and Reliable Data for Prevention and Policy-making Purposes
This presentation highlights the dangers of prolonged sitting at work, with musculoskeletal pain, cardiovascular disease and cancer being just some of the associated problems.
It outlines who is most at risk and gives handy tips and guidance for employers and workers to keep everyone moving.
This presentation provides an overview of the steps employers can take to support workers with chronic musculoskeletal disorders (MSDs) to manage their condition and continue to work.
Risk assessment is the basis for successful safety and health management, and the key to prevent and manage musculoskeletal disorders. This presentation suggests a straightforward stepwise approach to risk assessment that should work well for most businesses (specially micro and small enterprises).
This presentation provides a general introduction to the prevention and management of musculoskeletal disorders that could be complemented with other presentations or publications in the scope of Campaign 2020-22 Healthy Workplaces Lighten the Load.
The presentation summarizes the final output of a major project that was commissioned to address exposure to biological agents in the workplace and the related health effects. The study included a scientific literature review, interviews with experts, focus group sessions and a stakeholder workshop.
The presentation summarizes the final output of a major project that was commissioned to address exposure to biological agents in the workplace and the related health effects. The study included a scientific literature review, interviews with experts, focus group sessions and a stakeholder workshop.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...
Pan-European poll on occupational safety and health 2012
1. Pan-European opinion poll on occupational safety
and health
Results across 36 European countries
Representative sample in 36 participating European countries for the European
Agency for Safety and Health at Work (EU-OSHA)
Safety and Health at work is everyone's concern. It's good for you. It's good for business.
2. Opinion poll design
Universe: Population aged 18+ with usual place of residence and in the
respective language
Sample: Representative sample in each of the 36 participating European
countries
Method of data CATI (Computer-Assisted Telephone Interviews) across 31
collection: countries. In Bulgaria, the Czech Republic, Slovakia, Romania, and
Note: insert graphs,textconducted face here
Turkey, interviews were hereimages to face
Click to add tables,
Sample size: 35,540 interviews (approximately 1,000 per country except in
Liechtenstein with 200 interviews conducted)
Margin of error: 0.3 to 0.5 percentage points (across Europe)
Fieldwork period: 28th October 2011 - 17th January 2012
2
http://osha.europa.eu
3. Questionnaire overview
Q1. Do you think the number of people suffering from job-related stress in (your
country) will increase, decrease or stay around the same over the next five years?
(Increase a lot | Increase a little | Stay around the same | Decrease a little | Decrease a
lot)
Q2. Regarding safety and health risks at the workplace, do you consider yourself
….? (Very well informed | Fairly well informed | Not very well informed | Not at all
informed)
Q3. Many European governments are considering or have decided to increase
their retirement age because people are living for longer.
In your view, how important, if at all, are good health and safety practices to help
people work for longer before they retire? (Very important | Fairly important | Not very
important | Not at all important)
Q4. If you raised a health and safety problem in your workplace with your
supervisor, how confident are you that it would be addressed? (Very confident |
Fairly confident | Not very confident | Not at all confident)
Q5. How much do you agree or disagree with the following statement.
In order for (your country) to be economically competitive, workplaces need to
follow good health and safety practices? (Strongly agree | Tend to agree | Neither
agree nor disagree | Tend to disagree | Strongly disagree) 3
http://osha.europa.eu
4. Two-letter country designations used in charts
Letters Country Letters Country Letters Country
AL Albania HR Croatia NO Norway
AT Austria HU Hungary PL Poland
BE Belgium IE Ireland PT Portugal
BG Bulgaria IS Iceland RO Romania
CY Cyprus IT Italy RS Serbia
CZ Czech Republic LI Liechtenstein SE Sweden
Note: insert graphs,text hereimages here
Click to add tables,
DE Germany LT Lithuania SI Slovenia
DK Denmark LU Luxembourg SK Slovakia
EE Estonia LV Latvia TR Turkey
EL Greece ME Montenegro UK United Kingdom
ES Spain MK Former Yugoslav ALL All countries
Republic of Macedonia
FI Finland MT Malta 4
FR France NL Netherlands
http://osha.europa.eu
5. Regions used in this report
Region Countries
North Eastern Europe Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland,
Slovakia, Slovenia
North Western Europe Austria, Belgium, France, Germany, Ireland, Liechtenstein,
Luxembourg, Netherlands, United Kingdom
Nordic countries Denmark, Finland, Iceland, Norway, Sweden
South Eastern Europe Albania, Bulgaria, Croatia, Former Yugoslav Republic of Macedonia,
Note: insert graphs,textSerbia, Turkey here
Montenegro, Romania, hereimages
Click to add tables,
Southern Europe Cyprus, Greece, Italy, Malta, Portugal, Spain
EU27 The 27 countries that currently form the European Union
EU15 The 15 countries that formed the European Union until 1st May
2004
EEA Norway, Iceland, Liechtenstein
CCS Candidate and potential candidate countries
5
http://osha.europa.eu
7. Level of job-related stress
Do you think the number of people suffering from job-related stress in (your country)
will increase, decrease or stay around the same over the next five years? (%)
Increase a lot 49
Increase a little 28
Stay around the same 12
Decrease a little 4
Decrease a lot 3
Don’t know 4
7
Universe: Population aged 18+
http://osha.europa.eu
8. Level of job-related stress
Do you think the number of people suffering from job-related stress in (your country)
will increase, decrease or stay around the same over the next five years? (%)
Increase (aggregate) Stay around the same Decrease (aggregate)
Total 77 12
Male 76 13
Gender
Female 79 11
Aged 18-34 76 15
Age Aged 35-54 80 11
Aged 55+ 75 12
Active 80 12
Working status
Non active 75 13 8
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
9. Level of job-related stress
Do you think the number of people suffering from job-related stress in (your country)
will increase, decrease or stay around the same over the next five years? (%)
Increase (aggregate) Stay around the same Decrease (aggregate)
Total 79 12
0-9 78 12
Employer size 10-49 79 13
(number of
employees) 50-249 80 12
250+ 82 12
Employment Indefinite 80 12
contract Other 78 13
9
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
10. Level of job-related stress
Do you think the number of people suffering from job-related stress in (your country)
will increase, decrease or stay around the same over the next five years? (%)
Increase a lot Increase a little Stay around the same Decrease (aggregate)
3 4
3
2 1 8 8 3 4 4 1 9 7 1 8 9 3 4 9 2 6 6 2
7 11 14 9 14 6 7 10 7
10 5 6 5 8 11 8 12 15 15
7 2
9 17 7 16
10 14 10 13 13 12 16 17
8 14 13 11 16 11 17 22 21 8
18 15 18 14 18 13 25 18 27 28
21 17
17 24 27 8
24 24 30 28 28 27
28 33 30 28 33 31 40 28
17 22 26 25 26 33 34 32 40 46
36 37 41
29
39 42
83 47
69 69 64 20
63 60 58
54 54 52 52 51 50 50 49
47 47 46 46 44 44 44 44 43
41 40 39 39 36
34 34 33 31 29
27 26 22
16
E…
TR
CY
LU
LV
SK
LI
BE
ES
EE
SE
HR
HU
RO
AT
ME
MK
NL
NO
IT
EL
BG
SI
FR
ALL
AL
PL
CZ
IE
FI
IS
LT
DE
PT
RS
UK
DK
MT
10
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
11. Level of job-related stress
Do you think the number of people suffering from job-related stress in (your
country) will increase, decrease or stay around the same over the next five
years? (%)
Increase a lot Increase a little Stay around the same Decrease (aggregate)
7 7 6 8 8 5 4 5
3 8
13 9 12 9
12 13 16 23 13
28
26 32
28 27 27 37
32 27
41
45
49 50 51 55 49
43 42 47
28
17
Western
countries
EEA
countries
Southern
Eastern
EU27
EU15
CCS
Eastern
Europe
Europe
Europe
South
Europe
North
Nordic
North
All
11
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
12. Level of information about safety and
health risks at work
Level of information about safety and health risks at work
13. Level of information about safety and health risks
at work
Regarding safety and health risks at the workplace, do you consider yourself ….? (%)
Very well informed 24
Fairly well informed 43
Not very well informed 19
Not at all informed 8
Don’t know 6
13
Universe: Population aged 18+
http://osha.europa.eu
14. Level of information about safety and health risks
at work
Regarding safety and health risks at the workplace, do you consider yourself ….? (%)
Informed (aggregate) Not informed (aggregate)
Total 67 27
Male 70 26
Gender
Female 64 28
Aged 18-34 67 29
Age Aged 35-54 76 22
Aged 55+ 57 31
Active 82 18
Working status
Non active 50 38 14
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
15. Level of information about safety and health risks
at work
Regarding safety and health risks at the workplace, do you consider yourself ….? (%)
Informed (aggregate) Not informed (aggregate)
Total 82 18
0-9 78 20
Employer size 10-49 81 18
(number of
employees) 50-249 86 14
250+ 88 11
Employment Indefinite 83 16
contract Other 78 20
15
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
16. Level of information about safety and health risks
at work
Regarding safety and health risks at the workplace, do you consider yourself ….? (%)
Very well informed Fairly well informed Not very well informed Not at all informed
3 2 4 3 3 3 5 3 6 6 3 5 5 4 6 7 8 7 5 7 8 7 4 9 9 5 6 6
6 6 8 5 7 9 7 9 7 14 13 16 20 14 13 18 16 18
12 9
13 15 12 18 16 17 17 16 19 15 17 20 21
20 21
22 22 25 22
23 25
35 29
32 38 28 32
35 37 47 36 35
50 47 51 50
42 41 40 39 60
45 44 47
43 48 43
37 43 34 43 52 55 54
43 43 60
40
34 32 37 33
23 31 39
53 33
45 44 40
34 33 32 32 32 32 30 29 29 29
27 26 26 25 25 24 24 24 23
21 20 18 17 17 16 16 16 16
14 14 13 11 10 10
E…
BG
IE
FR
SI
TR
FI
UK
IS
LT
ALL
DK
PL
CZ
LI
EL
RS
AL
SE
EE
LV
DE
PT
CY
ES
SK
LU
BE
HR
HU
NL
NO
AT
MT
RO
IT
ME
MK
16
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
17. Level of information about safety and health risks
at work (employees only)
Regarding safety and health risks at the workplace, do you consider yourself ….? (%)
Very well informed Fairly well informed Not very well informed Not at all informed
1 2 2 2 2 4 2 3 3 2 4 1 2 5 3 3 1 2 1 4 1 3 3 2 7 6 4 6 4 3 5
6 6 5 4 4
8 4 10 11 14
6
8 9 9 11 7 8 15 8
12 10 12
10 10 12 14 14 11 11 16 13
14 17 9
16 19 20 25 22 27
31 27
36 39 24 27
47 48 30
43 47 52 47 46 45 54 52
56 55
43 43 48 48 52 49 59 58
51 48 55 59 61
46 46 69
44 48
43 44 52
29 44
62
56 53
45 44 42 41
39 39 39 39 39 38 37 37 36 35 34 34
33 33 28 28 28
27 27 26 26 25 25 23 23 22 22
19 18 16 15
E…
BG
IE
ALL
SI
FR
TR
FI
IS
LV
UK
PL
CZ
AT
DK
LI
PT
DE
CY
RS
AL
EL
BE
SE
EE
ES
SK
LU
HR
HU
MT
NL
NO
LT
IT
RO
ME
MK
17
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
18. Level of information about safety and health risks
at work
Regarding safety and health risks at the workplace, do you consider yourself ….? (%)
Very well informed Fairly well informed Not very well informed Not at all informed
8 6 6 4 6 5 3 8
7 16 8 16
17 17 14
19 17
23
32 30
47 43
44 44 42
43 43
48
38 36
33 31 35
24 26 27 27
19
11 12
Western
Eastern
Eastern
Southern
countries
countries
EEA
CCS
EU27
EU15
Europe
Europe
Europe
Europe
South
North
Nordic
North
All
18
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
19. Importance of workplace safety and
health for later retirement
Importance of workplace safety and health for later retirement
20. Importance of workplace safety and health for later
retirement
Many European governments are considering or have decided to increase their
retirement age because people are living for longer.
In your view, how important, if at all, are good health and safety practices to help
people work for longer before they retire? (%)
Very important 56
Fairly important 31
Not very important 5
Not at all important 4
Don’t know 4
20
Universe: Population aged 18+
http://osha.europa.eu
21. Importance of workplace safety and health for later
retirement
In your view, how important, if at all, are good health and safety
practices to help people work for longer before they retire? (%)
Important (aggregate) Not important (aggregate)
Total 87 9
Male 85 11
Gender Female 87 9
Aged 18-34 89 9
Age Aged 35-54 88 10
Aged 55+ 83 10
Active 89 10
Working status
Non active 85 10 21
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
22. Importance of workplace safety and health for later
retirement
In your view, how important, if at all, are good health and safety
practices to help people work for longer before they retire? (%)
Important (aggregate) Not important (aggregate)
Total 89 10
0-9 89 10
Employer size
Employer size
(number of 10-49 89 9
(number of
employees)
employees) 50-249 89 9
250+ 90 8
Employment Indefinite 89 9
contract Other 89 10
22
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
23. Importance of workplace safety and health for later
retirement
In your view, how important, if at all, are good health and safety
practices to help people work for longer before they retire? (%)
Very important Fairly important Not very important Not at all important
3 1 4 1 2 2 3 3 2 5 5 2 6 4 4 6 2 1 4 6 4 1 3
4 4 4 3 4 4 6 8 5 4 4 6 4 2 4 6 4 5 6 4 4
6 6 2 7 2
12 9 10 9 8 10
5 3 5 5 5 6 5 5 11
8 9 8 8 4
5 9 14
12 22 9 11 13 12
23 20 25 23
16 30 29 27 31 29 32 34
27
20 22 20 30 31 37 35
34 30 36 36
15 42
17 24 35
27
24 28 32 37 34
37
77
71 70 69 69 67 67
63 63 63 62 62 61 61 61 60 60 59
58 58 57 56 56 55 54 54 54
52 51 50 49 49
46 46 42
41 41 37
TR
LV
LU
LI
CY
EE
AT
SE
BE
SK
ES
HR
HU
RO
NO
EU27
ME
NL
IT
SI
MK
IS
IE
PL
LT
ALL
FR
EL
AL
BG
CZ
RS
FI
DK
DE
UK
PT
MT
23
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
24. Importance of workplace safety and health for later
retirement
In your view, how important, if at all, are good health and safety
practices to help people work for longer before they retire? (%)
Very important Fairly important Not very important Not at all important
4 4 5 2 3 4 4 3 3
6 3 6 4 6
5 6 6 7 5 6
33 30 27
31 30 31 37 29
33 33
56 57 56 59 58 58 61
52 53 52
Western
Southern
EEA
Eastern
Eastern
countries
countries
EU27
EU15
CCS
Europe
Europe
Europe
Europe
South
North
Nordic
North
All
24
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
25. Confidence in action to address
workplace safety and health problems
Confidence in action to address workplace safety and health problems
26. Confidence in action to address workplace safety and
health problems
If you raised a health and safety problem in your workplace with your
supervisor, how confident are you that it would be addressed? (%)
Very confident 40
Fairly confident 34
Not very confident 16
Not at all confident 7
Don’t know 3
26
Universe: Employees aged 18+
http://osha.europa.eu
27. Confidence in action to address workplace safety and
health problems
If you raised a health and safety problem in your workplace with your
supervisor, how confident are you that it would be addressed? (%)
Confident (aggregate) Not Confident (aggregate)
Total 74 23
Male 73 23
Gender
Female 74 23
Aged 18-34 74 23
Age Aged 35-54 74 23
Aged 55+ 70 24
27
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
28. Confidence in action to address workplace safety and
health problems
If you raised a health and safety problem in your workplace with your
supervisor, how confident are you that it would be addressed? (%)
Confident (aggregate) Not Confident (aggregate)
Total 74 23
0-9 69 27
Employer size
Employer size
(number of 10-49 74 23
(number of
employees)
employees) 50-249 77 22
250+ 79 19
Employment Indefinite 75 22
contract Other 69 26
28
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
29. Confidence in action to address workplace safety and
health problems
If you raised a health and safety problem in your workplace with your supervisor,
how confident are you that it would be addressed? (%)
Very confident Fairly confident Not very confident Not at all confident
2 3 1 1 2 4 3 7 3 2 5 7 8 7 4 9 8 6 13
6 6 9 6 8 6 8 6 11 10 8 9
12 14 9 11 11 14 10 9 13 17 15 17 20 14 19 18 20 18
14 15 12 16 15 15
20 20 15
14 21 18 28 18 16 23 21 26
24 31 30 33 23 19 24 26 32
36 21 29 24 27 28 31
24 35 37 36
26 34 38 34 47
38 36 35
34 40
30 34 41 38 36
32 41 45 46
27 26 30 27
71 69 32 31
62 58 57 37
56 53 52 20
48 47 46 45
41 40 40 36 36 36
35 32 31 31
29 27 27 27 26 25 25
23 23 21 19 18 18 18
17 13
TR
LU
CY
HU
LV
HR
NO
LI
SE
AT
ES
EE
RO
MK
BE
ME
SK
IS
SI
BG
IT
IE
NL
FR
PL
LT
FI
ALL
DK
EL
AL
CZ
RS
UK
DE
PT
EU27
MT
29
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
30. Confidence in action to address workplace safety and
health problems
If you raised a health and safety problem in your workplace with your supervisor,
how confident are you that it would be addressed? (%)
Very confident Fairly confident Not very confident Not at all confident
7 7 7 4 6 5 4
9 10 12
7 12 9
16 15 14 15
28 27 19
32
33 36
34 35 32
34
33 40
32
56
44 49 48
40 41 42
27 26 25
Western
Southern
Eastern
Eastern
countries
EEA
CCS
countries
EU27
EU15
Europe
Europe
Europe
Europe
South
North
Nordic
North
All
30
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
31. Importance of workplace safety and
health for economic competitiveness
Importance of workplace safety and health for economic competitiveness
32. Importance of workplace safety and health for economic
competitiveness (UK)
How much do you agree or disagree with the following statement.
In order for (your country) to be economically competitive, workplaces need
to follow good health and safety practices? (%)
Strongly agree 56
Tend to agree 30
Neither agree nor disagree 7
Tend to disagree 3
Strongly disagree 3
Don’t know 2
32
Universe: Population aged 18+
http://osha.europa.eu
33. Importance of workplace safety and health for economic
competitiveness (UK)
How much do you agree or disagree with the following statement.
In order for (your country) to be economically competitive, workplaces need
to follow good health and safety practices? (%)
Agree (aggregate) Neither agree nor disagree Disagree (aggregate)
Total 86 7 6
Male 85 7 6
Gender Female 86 7 5
Aged 18-34 84 10 5
Age Aged 35-54 87 6 6
Aged 55+ 86 5 6
Active 86 7 5
Working status
Non active 85 6 6 33
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
34. Importance of workplace safety and health for economic
competitiveness (UK)
How much do you agree or disagree with the following statement.
In order for (your country) to be economically competitive, workplaces need
to follow good health and safety practices? (%)
Agree (aggregate) Neither agree nor disagree Disagree (aggregate)
Total 86 7 5
0-9 86 7 6
Employer size
Employer size 10-49 86 7 5
(number of
(number of
employees)
employees) 50-249 87 8 4
250+ 87 8 4
Employment Permanent 86 7 6
contract Other 86 7 6
34
Difference to 100 per cent due to exclusion of Don't Know; Universe: Employees aged 18+
http://osha.europa.eu
35. Importance of workplace safety and health for economic
competitiveness
How much do you agree or disagree with the following statement.
In order for (your country) to be economically competitive, workplaces need to follow good health
and safety practices? (%)
Strongly agree Tend to agree Neither agree nor disagree Disagree (aggregate)
2 2 1
4 2 5 3 2 3 3 4 5 5 3 8 7 3 8 9 4 6 3 6 6 8 7 8 4 2 4
3 3 3 3 6 6 7 8
6 4 4 5 4 4
8 9 5 5 7 7 6 3 10 6
13 3 6 8 9 7 8 9 7 4 13 8 12
7 15 10 9 6 26 12
12 18 20 19 19 12
20 26 24 30 32
22 25 25 28
24 24 33 29 27 33 30 27 31 36 37 32 40 7
21 27 29 30 36 40 38
45 41
23 35
81
75 72 72 70
68 65 65 64 63
62 62 61 59 59 57 57 57 57
56 56 56 56 55 54 53 52 52 51
50 49 46 45
43 43
37 35 35
EU27
AL
EL
PL
BG
ALL
LT
IE
FR
IS
TR
SI
FI
LU
PT
CZ
CY
DE
RS
LV
UK
DK
LI
EE
MT
SE
AT
BE
SK
ES
HU
HR
RO
NO
NL
IT
MK
ME 35
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
36. Importance of workplace safety and health for economic
competitiveness
How much do you agree or disagree with the following statement.
In order for (your country) to be economically competitive, workplaces need to follow good health
and safety practices? (%)
Strongly agree Tend to agree Neither agree nor disagree Disagree (aggregate)
6 6 6 3 4 7 5 3 3 8
7 7 7 9 7 8 6 7 7 7
30 29 30 28 28 30 28
37 31 32
56 57 56 58 57 58 60 54
48 51
Western
CCS
countries
Eastern
countries
Eastern
Southern
EEA
EU27
EU15
Europe
Europe
Europe
Europe
South
North
Nordic
North
All
36
Difference to 100 per cent due to exclusion of Don't Know; Universe: Population aged 18+
http://osha.europa.eu
37. European Agency for Safety and Health at Work (EU-OSHA)
• Contributes to making Europe a safer, healthier and more productive place to
work;
• Researches, develops, and distributes reliable, balanced, and impartial safety
and health information;
• Organises pan-European awareness raising campaigns;
• Set up by the European Union in 1996 and based in Bilbao, Spain;
• Brings together representatives from the European Commission, Member
State governments, employers’ and workers’ organisations and leading
experts in each of the EU-27 Member States and beyond.
For more information about EU OSHA: http://osha.europa.eu
For more information on the pan-European poll on OSH:
http://osha.europa.eu/en/safety-health-in-figures/
37
http://osha.europa.eu