Ninja Rush is a classic shooter game where the player kills enemies to pass through levels. To complete a level, the player must not get killed by falling, getting hit by a ninja star, or hit by a ninja. As levels progress, the story and gameplay become more complex, with new chapters starting every five levels featuring a boss battle. Each chapter increases difficulty with more enemies, but also allows the player to collect more points for upgrades. Additionally, the game includes an endless runner mode where the player aims to score highest without dying in continuously running levels.