The document discusses osteosarcoma, a type of bone cancer. It provides background on the history and terminology of osteosarcoma, risk factors, common sites in the body, clinical presentation, diagnostic tools, staging systems, and treatments. Osteosarcoma most commonly affects the distal femur and proximal tibia in children and adolescents. Diagnosis involves imaging tests and biopsy. Treatment involves chemotherapy, surgery such as wide resection and reconstruction, and sometimes radiation. Prognosis has improved in recent decades with 5-year survival rates now around 60-85%.
Gastrojejunostomy is a surgical procedure that connects the stomach directly to the jejunum. It is indicated for patients with duodenal ulcers complicated by pyloric obstruction or nonresectable stomach or pancreatic cancers causing obstruction. The procedure involves opening the stomach and jejunum, suturing them together to form a stoma, then closing in multiple layers. Postoperatively, gastric emptying is monitored and diet advanced gradually to ensure proper healing.
This document discusses facial injuries, including causes, examination, classification, diagnosis, and management. It covers life-threatening airway issues from facial injuries and importance of careful examination. It classifies mid-face fractures as Le Fort I, II, III and describes characteristics and treatments. Zygomatic fractures and mandible fractures are also discussed, along with management of soft tissue injuries. Radiologic imaging plays a role in evaluation of facial fractures.
This document discusses benign and malignant neoplasms of the esophagus. It notes that leiomyoma is the most common benign neoplasm. Risk factors for esophageal cancer include smoking, alcohol consumption, and Barrett's esophagus. There are two main types of esophageal cancer - squamous cell carcinoma, which arises in the upper esophagus, and adenocarcinoma, which occurs in the lower esophagus. Symptoms include dysphagia and weight loss. Treatment depends on the location and stage of disease, and may include surgery, radiation, stents or feeding tubes. Prognosis is generally poor with five-year survival rates below 10%.
Like the playlist in YouTube, in this presentation I have combined three of my presentation into one for the benefit of medical students and surgical trainees. The first presentation regading introduction to breast pathologies, second regarding benign breast lesions and the third one is regarding Carcinoma Breast. Hope you will enjoy this.
This document provides an overview of various osteotomy approaches for accessing lesions in the skull base and neck. It discusses the history, classification, advantages, and disadvantages of different osteotomies. Key approaches mentioned include fronto-nasal-orbital osteotomy, Lefort I osteotomy, zygomatic osteotomy, and mandibulotomy. The document emphasizes that the choice of osteotomy depends on factors like the location and extent of the lesion as well as involvement of surrounding structures. Modifications to standard approaches are also described to optimize exposure and resection of different pathologies.
Whipple's procedure - Indications, Steps, ComplicationsVikas V
The document describes the Whipple procedure, which was first performed by Dr. Allen Whipple in 1935. It involves removing the head of the pancreas, part of the small intestine, the gallbladder, and bile duct. The original procedure was done in two stages but is now typically done in one stage. The document outlines the key steps of the modern Whipple procedure, including mobilizing tissues, dividing vessels, transecting organs, and reconstructing the digestive and biliary systems with anastomoses. Vascular resection of veins like the splenic vein may sometimes be required as well.
Gastrojejunostomy is a surgical procedure that connects the stomach directly to the jejunum. It is indicated for patients with duodenal ulcers complicated by pyloric obstruction or nonresectable stomach or pancreatic cancers causing obstruction. The procedure involves opening the stomach and jejunum, suturing them together to form a stoma, then closing in multiple layers. Postoperatively, gastric emptying is monitored and diet advanced gradually to ensure proper healing.
This document discusses facial injuries, including causes, examination, classification, diagnosis, and management. It covers life-threatening airway issues from facial injuries and importance of careful examination. It classifies mid-face fractures as Le Fort I, II, III and describes characteristics and treatments. Zygomatic fractures and mandible fractures are also discussed, along with management of soft tissue injuries. Radiologic imaging plays a role in evaluation of facial fractures.
This document discusses benign and malignant neoplasms of the esophagus. It notes that leiomyoma is the most common benign neoplasm. Risk factors for esophageal cancer include smoking, alcohol consumption, and Barrett's esophagus. There are two main types of esophageal cancer - squamous cell carcinoma, which arises in the upper esophagus, and adenocarcinoma, which occurs in the lower esophagus. Symptoms include dysphagia and weight loss. Treatment depends on the location and stage of disease, and may include surgery, radiation, stents or feeding tubes. Prognosis is generally poor with five-year survival rates below 10%.
Like the playlist in YouTube, in this presentation I have combined three of my presentation into one for the benefit of medical students and surgical trainees. The first presentation regading introduction to breast pathologies, second regarding benign breast lesions and the third one is regarding Carcinoma Breast. Hope you will enjoy this.
This document provides an overview of various osteotomy approaches for accessing lesions in the skull base and neck. It discusses the history, classification, advantages, and disadvantages of different osteotomies. Key approaches mentioned include fronto-nasal-orbital osteotomy, Lefort I osteotomy, zygomatic osteotomy, and mandibulotomy. The document emphasizes that the choice of osteotomy depends on factors like the location and extent of the lesion as well as involvement of surrounding structures. Modifications to standard approaches are also described to optimize exposure and resection of different pathologies.
Whipple's procedure - Indications, Steps, ComplicationsVikas V
The document describes the Whipple procedure, which was first performed by Dr. Allen Whipple in 1935. It involves removing the head of the pancreas, part of the small intestine, the gallbladder, and bile duct. The original procedure was done in two stages but is now typically done in one stage. The document outlines the key steps of the modern Whipple procedure, including mobilizing tissues, dividing vessels, transecting organs, and reconstructing the digestive and biliary systems with anastomoses. Vascular resection of veins like the splenic vein may sometimes be required as well.
This document discusses various craniofacial syndromes and deformities, their causes and characteristics. It describes Pierre Robin sequence, featuring micrognathia, glossoptosis and cleft palate. It also discusses Treacher Collins syndrome, characterized by mandibulofacial dysostosis due to defects of the first and second branchial arches. Several craniosynostosis syndromes are outlined, including Crouzon syndrome, Apert syndrome, Pfeiffer syndrome, and cloverleaf skull syndrome. Surgical treatments aim to decompress the brain, reshape the skull, and reconstruct midface and jaw deformities.
This document discusses the anatomy, etiology, clinical presentation, staging, and treatment options for carcinoma of the tongue. It notes that carcinoma of the tongue most commonly presents as a non-healing ulcer and can cause symptoms like otalgia, odynophagia, and bleeding. Treatment depends on staging and may involve surgery, radiation therapy, chemotherapy, or a combination. Prognosis decreases with more advanced stage at diagnosis.
1) The document discusses motility disorders of the esophagus, including achalasia, diffuse esophageal spasm, nutcracker esophagus, and ineffective esophageal motility.
2) It provides details on the anatomy, physiology and functions of the esophagus, as well as the classification, symptoms, investigations and treatments of various esophageal motility disorders.
3) Achalasia is characterized by failure of the lower esophageal sphincter to relax during swallowing, leading to symptoms like dysphagia and regurgitation. It is diagnosed using barium swallow, chest X-ray and manometry. Treatment involves botox injections or surgical myotomy.
1. Salivary gland neoplasms are relatively rare, accounting for 6% of head and neck tumors, with parotid gland tumors making up 80% of cases.
2. Clinical presentation depends on whether the tumor is benign or malignant. Benign tumors usually present as asymptomatic swellings while malignant tumors can present with pain, nerve palsies, or nodal metastases.
3. Diagnosis involves investigations like ultrasound, CT, MRI and biopsy to determine the nature and extent of the tumor. However, differentiating between benign and malignant, and identifying the exact histology can still be challenging.
Pleomorphic adenoma is the most common benign tumor of the parotid gland. It consists of both epithelial cells and spindle-shaped mesenchymal cells within an abundant mucoid matrix. On pathology, it displays well-differentiated epithelial cells and spindle/stellate cells in a pleomorphic stroma with mucoid material. The tumor presents as a slow-growing, painless swelling of the parotid gland and is diagnosed by FNAC. The treatment is complete surgical excision via superficial parotidectomy while preserving the facial nerve. Recurrence is possible if there are pseudopods left behind or inadequate margins. Malignant transformation may occur in long-standing tumors.
The document discusses different procedures for inguinal lymph node dissection, including standard, modified, and radical dissection. It describes key aspects of modified inguinal lymphadenectomy such as a shorter skin incision and preservation of structures like the saphenous vein. Complications of inguinal node dissection are also outlined, ranging from minor issues like lymphocele and wound infection to major complications including debilitating lymphedema, flap necrosis, and blood clots. The document provides details on surgical techniques, postoperative care, and risks associated with dissection of lymph nodes in the groin area.
Lymphangiomas are benign tumors of lymphatic vessels that most commonly occur in the head and neck region, particularly the tongue. They can also occasionally be found in the oral cavity elsewhere like the palate, cheeks, or lips. Lymphangiomas are generally classified as simple, cavernous, cellular, or diffuse systemic and can be either cystic or microcystic/macrocystic. Treatment options include surgical excision, sclerotherapy, cryotherapy, laser therapy, and other conservative treatments. Complete surgical removal is often difficult due to the risk of damaging surrounding vital structures and high chance of recurrence.
The document describes several techniques for examining the thyroid gland through physical examination. It discusses inspecting and palpating the thyroid anteriorly and laterally to check for size, texture, mobility, tenderness, and nodules. Examining the thyroid can help determine if a goiter is present and the possibility of thyroid disease. While inspection and palpation are described, the accuracy of physical examination alone is limited, and combining physical findings with symptoms increases accuracy in assessing thyroid function.
The pectoralis major flap uses the pectoralis major muscle and overlying skin to reconstruct head and neck defects. It has a reliable blood supply from the thoracoacromial artery. The muscle is raised from the chest wall and tunneled to the defect site. The skin paddle size and position can be adjusted depending on the location and size of the defect. Complications are rare but include infection, partial flap necrosis, and donor site issues. It provides a bulky well-vascularized tissue for reconstruction with minimal morbidity.
This document discusses esophageal motility disorders. It begins with the anatomy of the esophagus, including its three parts (cervical, thoracic, abdominal) and normal narrowings. It then covers the physiology of peristalsis and swallowing. The main types of esophageal motility disorders are described - achalasia (failure of LES to relax), spastic disorders like DES and nutcracker esophagus, and presbyoesophagus in elderly patients. Diagnostic tests like manometry and scintigraphy transit tests are also summarized.
This presentation is having Mindmaps for various causes for Groin swellings. It is also having Diagnostic algorithm for groin swellings and important tabular colums for Groin swellings. it would be helpful for rapid revision of Groin swelling problem.
Mohs micrographic surgery is a technique for completely removing skin cancer lesions. It involves the surgeon also acting as the pathologist to examine tissue sections under the microscope between surgical stages. The procedure involves removing tissue in blocks that are each examined microscopically until the edges are clear of cancer cells. Additional blocks are coded separately and any biopsies or repairs performed on the same day are also separately coded.
Breast procedures include incision and drainage of cysts, excision of tumors or biopsies, placement of localization devices, partial or total mastectomy, and stereotactic biopsy using imaging to target microcalcifications. Reconstruction techniques aim to repair the breast and can involve augmentation or mastopexy.
The document describes the pectoralis major island flap technique. It can be used for reconstruction of the pharynx, tongue, face, neck, and skullbase defects. The flap has a large arc of rotation from the clavicle to the xiphoid process. It provides a single stage transfer with a muscle carrier but does not match the color and texture of facial skin. The document outlines the surgical technique including flap design, elevation of the vascular pedicle, and closure of the donor site. Variations including osteomyocutaneous flaps with rib bone and use of the flap as a free tissue transfer are also discussed. Complications, risk factors, and modifications to the technique are summarized.
P53 immunostaining shows genetic alterations in the epithelium surrounding head and neck squamous cell carcinoma (HNSCC) tumors, supporting the concept of field cancerization. Field cancerization involves the formation of multiple premalignant patches within an exposed area due to environmental carcinogens, which can later coalesce and lead to secondary tumors even after complete surgical removal of the primary tumor. The molecular markers and genetic changes detected in premalignant fields correlate with progression to invasive cancer and help explain the development of recurrent and new primary tumors in the oral cavity.
This presentation is intended for diagnosing various vascular lesions on the basis of history and clinical examination. It covers a broad range of anomalies plus you can test yourself in the end.
This document outlines the procedure for thyroidectomy. It begins with definitions and indications for thyroid surgery, which include toxic multinodular goiter and malignant thyroid tumors. It describes the types of thyroidectomy that can be performed and the pre-operative preparation, including rendering thyrotoxic patients euthyroid. The procedure involves an incision above the sternum, identification and preservation of the recurrent laryngeal nerve and parathyroid glands, ligation of vessels, and removal of the thyroid. Post-operative management includes monitoring for complications such as hemorrhage, nerve injury, and hypocalcemia.
This document provides information on benign and malignant diseases of the salivary glands, including:
1. It discusses the embryology, surgical anatomy, non-neoplastic conditions, benign tumors, and malignant tumors of the major and minor salivary glands.
2. It describes common benign tumors like pleomorphic adenoma and Warthin's tumor, as well as malignant tumors such as mucoepidermoid carcinoma.
3. It provides details on the classification, clinical features, histology, treatment and prognosis of various salivary gland neoplasms.
This document discusses different types of flaps used in reconstructive surgery. It begins with a brief history of flap surgery and then defines the key differences between flaps and grafts. It provides classifications of flaps based on congruity, circulation, and anatomical components. The main types of flaps discussed are skin flaps, muscle flaps, and fascia flaps. Postoperative monitoring and potential complications are also summarized.
Dysphagia is a common symptom that requires early evaluation to determine if it is caused by issues in the oropharynx or esophagus. A thorough history and physical exam can identify 80-85% of causes, while tests like modified barium swallow, endoscopy, and manometry provide further information. Treatment depends on the underlying problem, such as dilation for strictures, surgery for obstructions, or lifestyle/medication changes for conditions like GERD. Early diagnosis and treatment can help address dysphagia's underlying cause.
1) The document lists 50 candidates who have been provisionally selected for admission to the M.Sc (Statistics) morning program for the fall 2014 semester at Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi.
2) The selected candidates must deposit their fees by September 22, 2014 or their candidacy will be cancelled.
3) The selected candidates must produce their original documents at the time of registration or their admission offer will be treated as cancelled. Regular classes will begin on September 29, 2014.
This document discusses various craniofacial syndromes and deformities, their causes and characteristics. It describes Pierre Robin sequence, featuring micrognathia, glossoptosis and cleft palate. It also discusses Treacher Collins syndrome, characterized by mandibulofacial dysostosis due to defects of the first and second branchial arches. Several craniosynostosis syndromes are outlined, including Crouzon syndrome, Apert syndrome, Pfeiffer syndrome, and cloverleaf skull syndrome. Surgical treatments aim to decompress the brain, reshape the skull, and reconstruct midface and jaw deformities.
This document discusses the anatomy, etiology, clinical presentation, staging, and treatment options for carcinoma of the tongue. It notes that carcinoma of the tongue most commonly presents as a non-healing ulcer and can cause symptoms like otalgia, odynophagia, and bleeding. Treatment depends on staging and may involve surgery, radiation therapy, chemotherapy, or a combination. Prognosis decreases with more advanced stage at diagnosis.
1) The document discusses motility disorders of the esophagus, including achalasia, diffuse esophageal spasm, nutcracker esophagus, and ineffective esophageal motility.
2) It provides details on the anatomy, physiology and functions of the esophagus, as well as the classification, symptoms, investigations and treatments of various esophageal motility disorders.
3) Achalasia is characterized by failure of the lower esophageal sphincter to relax during swallowing, leading to symptoms like dysphagia and regurgitation. It is diagnosed using barium swallow, chest X-ray and manometry. Treatment involves botox injections or surgical myotomy.
1. Salivary gland neoplasms are relatively rare, accounting for 6% of head and neck tumors, with parotid gland tumors making up 80% of cases.
2. Clinical presentation depends on whether the tumor is benign or malignant. Benign tumors usually present as asymptomatic swellings while malignant tumors can present with pain, nerve palsies, or nodal metastases.
3. Diagnosis involves investigations like ultrasound, CT, MRI and biopsy to determine the nature and extent of the tumor. However, differentiating between benign and malignant, and identifying the exact histology can still be challenging.
Pleomorphic adenoma is the most common benign tumor of the parotid gland. It consists of both epithelial cells and spindle-shaped mesenchymal cells within an abundant mucoid matrix. On pathology, it displays well-differentiated epithelial cells and spindle/stellate cells in a pleomorphic stroma with mucoid material. The tumor presents as a slow-growing, painless swelling of the parotid gland and is diagnosed by FNAC. The treatment is complete surgical excision via superficial parotidectomy while preserving the facial nerve. Recurrence is possible if there are pseudopods left behind or inadequate margins. Malignant transformation may occur in long-standing tumors.
The document discusses different procedures for inguinal lymph node dissection, including standard, modified, and radical dissection. It describes key aspects of modified inguinal lymphadenectomy such as a shorter skin incision and preservation of structures like the saphenous vein. Complications of inguinal node dissection are also outlined, ranging from minor issues like lymphocele and wound infection to major complications including debilitating lymphedema, flap necrosis, and blood clots. The document provides details on surgical techniques, postoperative care, and risks associated with dissection of lymph nodes in the groin area.
Lymphangiomas are benign tumors of lymphatic vessels that most commonly occur in the head and neck region, particularly the tongue. They can also occasionally be found in the oral cavity elsewhere like the palate, cheeks, or lips. Lymphangiomas are generally classified as simple, cavernous, cellular, or diffuse systemic and can be either cystic or microcystic/macrocystic. Treatment options include surgical excision, sclerotherapy, cryotherapy, laser therapy, and other conservative treatments. Complete surgical removal is often difficult due to the risk of damaging surrounding vital structures and high chance of recurrence.
The document describes several techniques for examining the thyroid gland through physical examination. It discusses inspecting and palpating the thyroid anteriorly and laterally to check for size, texture, mobility, tenderness, and nodules. Examining the thyroid can help determine if a goiter is present and the possibility of thyroid disease. While inspection and palpation are described, the accuracy of physical examination alone is limited, and combining physical findings with symptoms increases accuracy in assessing thyroid function.
The pectoralis major flap uses the pectoralis major muscle and overlying skin to reconstruct head and neck defects. It has a reliable blood supply from the thoracoacromial artery. The muscle is raised from the chest wall and tunneled to the defect site. The skin paddle size and position can be adjusted depending on the location and size of the defect. Complications are rare but include infection, partial flap necrosis, and donor site issues. It provides a bulky well-vascularized tissue for reconstruction with minimal morbidity.
This document discusses esophageal motility disorders. It begins with the anatomy of the esophagus, including its three parts (cervical, thoracic, abdominal) and normal narrowings. It then covers the physiology of peristalsis and swallowing. The main types of esophageal motility disorders are described - achalasia (failure of LES to relax), spastic disorders like DES and nutcracker esophagus, and presbyoesophagus in elderly patients. Diagnostic tests like manometry and scintigraphy transit tests are also summarized.
This presentation is having Mindmaps for various causes for Groin swellings. It is also having Diagnostic algorithm for groin swellings and important tabular colums for Groin swellings. it would be helpful for rapid revision of Groin swelling problem.
Mohs micrographic surgery is a technique for completely removing skin cancer lesions. It involves the surgeon also acting as the pathologist to examine tissue sections under the microscope between surgical stages. The procedure involves removing tissue in blocks that are each examined microscopically until the edges are clear of cancer cells. Additional blocks are coded separately and any biopsies or repairs performed on the same day are also separately coded.
Breast procedures include incision and drainage of cysts, excision of tumors or biopsies, placement of localization devices, partial or total mastectomy, and stereotactic biopsy using imaging to target microcalcifications. Reconstruction techniques aim to repair the breast and can involve augmentation or mastopexy.
The document describes the pectoralis major island flap technique. It can be used for reconstruction of the pharynx, tongue, face, neck, and skullbase defects. The flap has a large arc of rotation from the clavicle to the xiphoid process. It provides a single stage transfer with a muscle carrier but does not match the color and texture of facial skin. The document outlines the surgical technique including flap design, elevation of the vascular pedicle, and closure of the donor site. Variations including osteomyocutaneous flaps with rib bone and use of the flap as a free tissue transfer are also discussed. Complications, risk factors, and modifications to the technique are summarized.
P53 immunostaining shows genetic alterations in the epithelium surrounding head and neck squamous cell carcinoma (HNSCC) tumors, supporting the concept of field cancerization. Field cancerization involves the formation of multiple premalignant patches within an exposed area due to environmental carcinogens, which can later coalesce and lead to secondary tumors even after complete surgical removal of the primary tumor. The molecular markers and genetic changes detected in premalignant fields correlate with progression to invasive cancer and help explain the development of recurrent and new primary tumors in the oral cavity.
This presentation is intended for diagnosing various vascular lesions on the basis of history and clinical examination. It covers a broad range of anomalies plus you can test yourself in the end.
This document outlines the procedure for thyroidectomy. It begins with definitions and indications for thyroid surgery, which include toxic multinodular goiter and malignant thyroid tumors. It describes the types of thyroidectomy that can be performed and the pre-operative preparation, including rendering thyrotoxic patients euthyroid. The procedure involves an incision above the sternum, identification and preservation of the recurrent laryngeal nerve and parathyroid glands, ligation of vessels, and removal of the thyroid. Post-operative management includes monitoring for complications such as hemorrhage, nerve injury, and hypocalcemia.
This document provides information on benign and malignant diseases of the salivary glands, including:
1. It discusses the embryology, surgical anatomy, non-neoplastic conditions, benign tumors, and malignant tumors of the major and minor salivary glands.
2. It describes common benign tumors like pleomorphic adenoma and Warthin's tumor, as well as malignant tumors such as mucoepidermoid carcinoma.
3. It provides details on the classification, clinical features, histology, treatment and prognosis of various salivary gland neoplasms.
This document discusses different types of flaps used in reconstructive surgery. It begins with a brief history of flap surgery and then defines the key differences between flaps and grafts. It provides classifications of flaps based on congruity, circulation, and anatomical components. The main types of flaps discussed are skin flaps, muscle flaps, and fascia flaps. Postoperative monitoring and potential complications are also summarized.
Dysphagia is a common symptom that requires early evaluation to determine if it is caused by issues in the oropharynx or esophagus. A thorough history and physical exam can identify 80-85% of causes, while tests like modified barium swallow, endoscopy, and manometry provide further information. Treatment depends on the underlying problem, such as dilation for strictures, surgery for obstructions, or lifestyle/medication changes for conditions like GERD. Early diagnosis and treatment can help address dysphagia's underlying cause.
1) The document lists 50 candidates who have been provisionally selected for admission to the M.Sc (Statistics) morning program for the fall 2014 semester at Pir Mehr Ali Shah Arid Agriculture University, Rawalpindi.
2) The selected candidates must deposit their fees by September 22, 2014 or their candidacy will be cancelled.
3) The selected candidates must produce their original documents at the time of registration or their admission offer will be treated as cancelled. Regular classes will begin on September 29, 2014.
Wali Ullah provides his curriculum vitae, including personal details, education history, computer skills, and interpersonal skills. He has a bachelor's degree in Tourism and Hospitality from Hazara University, with a GPA of 2.9, and is currently pursuing a certificate in art and a diploma of information technology. His objective is to find a responsible and rewarding position that allows for career growth and development.
The document discusses the anatomy of the heart. It describes the location of the heart in the mediastinum and its structure including four chambers (right atrium, left atrium, right ventricle, left ventricle), valves (tricuspid, mitral, pulmonary, aortic), vessels (coronary arteries), and layers (pericardium). It also outlines the surfaces, borders and conduction system of the heart.
Landing your next opportunity getting a job & thriving in itNaeem Zafar
Presentation on tips and tricks on getting a job and curating a career. How to get ahead by Naeem Zafar (from OPEN Forum 2014 in Silicon Valley). 30 years of experience in interviewing and hiring talent.
Case Study: University of California, Berkeley and San FranciscoForgeRock
Presented by Dedra Chamberlin Deputy Director, Identity and Access Management University of California, Berkeley and San Francisco, Francesco Meschia IAM Engineer, UC Berkeley and Mukesh Yadav, IAM Engineer, UC San Francisco at ForgeRock Open Stack Identity Summit, June 2013
Learn more about ForgeRock Access Management:
https://www.forgerock.com/platform/access-management/
Learn more about ForgeRock Identity Management:
https://www.forgerock.com/platform/identity-management/
The UC Berkeley ecosystem supports entrepreneurship through talented students and faculty, technology licensing, specialized entrepreneurship programs, and incubators/accelerators. Berkeley has helped develop new industries like computing, biotech, and databases through seminal research projects. This research provides the basis for spin-off companies and the broader clusters that form. Today, multidisciplinary institutions at Berkeley further support entrepreneurship by connecting students from different backgrounds.
Sikandar Khan has over 45 years of experience in civil engineering and management of hydropower projects. He currently serves as the Team Leader for the 40.8 MW KOTO Hydropower Project in Khyber Pakhtunkhwa, where he is responsible for preparing bidding documents, evaluating bids, and overseeing project implementation. Throughout his career, he has worked on numerous hydropower, dam, irrigation and infrastructure projects, taking on roles such as project manager, team leader, and resident engineer. He has extensive international experience in addition to working on major projects across Pakistan.
This document provides information about osteosarcoma, including:
- It is a primary malignant bone tumor most common in children and adolescents.
- Signs and symptoms include bone pain, swelling, decreased joint motion, and pathological fractures.
- Diagnosis involves imaging like x-rays, CT, MRI along with biopsy.
- Staging uses systems like Enneking staging which considers tumor grade and compartmentalization.
- Treatment involves chemotherapy, surgery such as wide resection and reconstruction with prosthetics or grafts, and sometimes radiation. Prognosis has improved to a 5-year survival rate of 60-85% with current therapies.
This document discusses different types of malignant bone tumors. It describes chondrosarcoma, which arises from cartilage and most commonly affects men in their fourth and fifth decades. Primary chondrosarcoma occurs in tubular bones and shows radiolucent areas with central calcification on X-rays. Secondary chondrosarcoma arises from osteochondromas that have been present since childhood. Osteosarcoma is another type of malignant bone tumor that most commonly involves long bone metaphyses in children and adolescents. It appears as hazy osteolytic areas alternating with dense areas on X-rays. Treatment for these tumors involves wide resection or prosthetic replacement followed by chemotherapy.
1362576264 lab measures in diabetic foot mumbaidfsimedia
The document discusses laboratory measures for evaluating the diabetic foot, including sensory and vascular assessments. Sensory tests include Semmes-Weinstein monofilament, vibration perception with tuning fork, and biothesiometry. Vascular tests include examination of pulses, ankle-brachial index, and Doppler ultrasound. Other evaluations include foot pressure studies, x-rays, MRI, and wound cultures to guide antibiotic treatment of foot infections in diabetes. Regular foot exams emphasizing sensory and vascular assessments can help prevent costly and life-threatening diabetic foot ulcers and amputations.
This document provides an overview of the pituitary gland and hypothalamus. It describes the pituitary gland's location and structure, including its anterior and posterior lobes. The anterior lobe contains cells that secrete hormones like growth hormone and prolactin. Common pituitary tumors are also summarized, such as prolactin-secreting prolactinomas. Conditions of hyper- and hypopituitarism are outlined as well as symptoms of pituitary disease.
Cancer of Oesophagus and Stomach - Treatment & Information in Kuching, SarawakTimberlandMedicalCentre
For more information, visit https://www.timberlandmedical.com
This presentation is by Dr. Wong Kwong Hieng (MBBch,FRCS,AM) General Surgeon at Timberland Medical Centre.
Timberland Medical Centre is a private hospital that has been in operation since 1994. We are strategically located at the 3rd Mile roundabout on Jalan Rock, Kuching, Sarawak, East Malaysia. Our hospital is 10 minutes from the Kuching International Airport and 15 minutes from the Central Bus Terminal. We continually seek to improve and upgrade our services and facilities, as we strive to provide the best medical care for our patients and customers.
Gout is a metabolic disorder resulting from elevated uric acid levels and deposition of urate crystals in the joints. It is characterized by recurrent attacks of acute inflammatory arthritis, deposition of urate crystals in and around joints, and possible kidney and bladder stone formation. Diagnosis involves identifying urate crystals in joint fluid or tophi. Treatment involves anti-inflammatory drugs like colchicine for acute attacks and long-term urate-lowering therapy using drugs like allopurinol or febuxostat. Lifestyle changes and diet modifications can also help control uric acid levels.
Gout is a metabolic disorder resulting from elevated uric acid levels and deposition of urate crystals in the joints. It involves a spectrum of conditions including hyperuricemia, acute inflammatory arthritis attacks, tophaceous deposits of urate crystals in and around joints, renal disease, and kidney stones. Gout typically involves recurrent attacks of severe pain and swelling in joints like the first metatarsophalangeal joint. Chronic untreated gout can cause permanent joint damage and deformity from urate tophi. Diagnosis involves identifying urate crystals in joint fluid or tissues.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.
Hypospadias is a birth defect where the urethral opening is on the underside of the penis instead of at the tip. It occurs when the urethra fails to fuse completely during development in the womb between 8-15 weeks of gestation. Hypospadias is associated with chordee, where the penis curves downward, and can be associated with other anomalies like cryptorchidism. Surgical repair is usually done between ages 4-18 months to correct the urethral opening, straighten any chordee, and for cosmetic and functional reasons. Investigations help assess the severity and rule out other anomalies while medical treatment may help with microphallus prior to surgery.
The document describes several different bone lesions and tumors that can occur in the jaw. It provides radiographs and microscopic images of osteoma, Gardner syndrome, osteoblastoma, cementoblastoma, desmoplastic fibroma, hemangioma, osteosarcoma, chondroblastic osteosarcoma, fibroblastic osteosarcoma, pigmented neuroectodermal tumor, Burkitt's lymphoma, angiocentric T-cell lymphoma, multiple myeloma, and Langerhans cell histiocytosis. For each condition, it shows the characteristic radiographic or microscopic appearance.
This document discusses the diagnosis and treatment of cervical spondylotic myelopathy. It begins with a brief history of the condition and its early treatments. It then covers the epidemiology, pathophysiology, clinical presentation, diagnostic imaging, and grading scales used to evaluate the severity of myelopathy. Key points include the natural degenerative processes that cause spinal canal narrowing, common symptoms like neck stiffness and leg weakness, and the use of MRI to identify cord/canal compression and signal changes indicative of edema or cystic necrosis. Surgical intervention aims to decompress the spinal cord through procedures like laminectomy or laminoplasty to relieve pressure on the spinal cord.
This document provides a history of thyroid diseases and surgery. It discusses early descriptions of goiter in 2700 BC China and advances in thyroid surgery from the first excision in 500 AD Baghdad to improved techniques and outcomes in the late 1800s. Key developments include recognizing the thyroid's role in hormone production and establishing links between iodine intake and goiter. Common benign thyroid disorders like goiter are also overviewed, outlining causes, pathogenesis, and treatment considerations.
Bone tumours and principles of limb salvage surgeryPaudel Sushil
This document discusses various types of bone tumors including benign and malignant lesions. It covers topics such as hyperplasia, metaplasia, anaplasia, neoplasia, and the TNM classification system. Various bone forming, cartilage, fibrogenic, round cell, vascular, and miscellaneous tumors and tumor-like lesions are described. The principles of limb salvage surgery for extremity sarcomas are also mentioned.
Otosclerosis is a metabolic bone disease that causes abnormal bone growth in the ossicles of the middle ear, commonly fixing the stapes bone. It most often presents between ages 15-45 and risk factors include family history and metabolic abnormalities. Symptoms include hearing loss and tinnitus. Diagnosis involves audiometry, otoscopic examination, and CT scan. Treatment options include stapedotomy or stapedectomy surgery as well as hearing aids or fluoride therapy for non-surgical candidates or those who decline surgery. The goal of treatment is to restore hearing by improving sound conduction through the middle ear.
Otosclerosis is a metabolic bone disease that causes abnormal bone growth in the ossicles of the middle ear, commonly fixing the stapes bone. It most often presents between ages 15-45 and risk factors include family history and metabolic abnormalities. Symptoms include hearing loss and tinnitus. Diagnosis involves audiometry, otoscopic examination, and CT scan. Treatment options include stapedotomy or stapedectomy surgery as well as hearing aids or fluoride therapy for non-surgical candidates or those who decline surgery. The goal of treatment is to restore hearing by improving sound conduction through the middle ear.
This document discusses various types of non-inflammatory arthritis including osteoarthritis, neuropathic arthritis, acute rheumatic fever, and ochronosis. It focuses on osteoarthritis, describing it as a non-inflammatory degenerative joint disease characterized by cartilage loss, new bone formation, and fibrosis. Symptoms include pain, swelling, stiffness and deformity. X-ray findings include joint space narrowing, sclerosis, and osteophyte formation. Treatment involves protecting joints, exercises, analgesics, and occasionally surgery such as arthroscopy or joint replacement. Neuropathic arthritis and other types are also briefly summarized.
This document discusses the clinical applications of Doppler ultrasound. It begins by outlining the advantages and disadvantages of Doppler, then describes its use in evaluating the extremities, renal and hepatic vessels, carotid arteries, male and female genital systems, obstetrics, inflammation, and masses. Doppler is described as a safe, rapid and low-cost imaging method that has expanded diagnostic capabilities in radiology. It can be used to diagnose many medical and surgical conditions involving blood flow.
Developmental dysplasia of the hip (DDH) is a spectrum disorder ranging from mild dysplasia to frank dislocation of the hip. Risk factors include female sex, first born children, family history, and breech positioning. Diagnosis involves a thorough physical exam including Ortolani's and Barlow's maneuvers and may include imaging like x-rays and ultrasound. Treatment depends on age and severity, ranging from harness or casting for younger infants to closed or open reduction and casting/bracing for older infants and children. Complications can include avascular necrosis if reduction is not performed carefully.
This document discusses kyphoplasty for treating acute osteoporotic vertebral compression fractures. It begins by thanking various professors and outlines the purpose of studying kyphoplasty's role in managing such fractures by analyzing clinical and radiographic outcomes to evaluate its efficacy and safety. Vertebral compression fractures are a common osteoporosis complication and can cause spinal deformities, pain, disability and reduced function. Kyphoplasty is a minimally invasive procedure that can restore height and provide immediate pain relief with fewer complications than vertebroplasty. The document discusses patient selection criteria, technique, potential complications, and outcomes of kyphoplasty for treating osteoporotic vertebral compression fractures.
The document describes a study of 65 cases of benign and malignant neoplasms in ruminants over a 3 year period. The neoplasms included 2 fibromas, 1 fibromatous epulis, 1 fibroadenoma, 4 fibropapillomas, 25 cutaneous papillomas, 8 keratoacanthomas, 2 fibrosarcomas, 21 squamous cell carcinomas, and 1 lymphosarcoma. The neoplasms were surgically treated and followed up for 4-6 months. The study aimed to describe the gross and histopathological features of various ruminant neoplasms and determine which cases were suitable for surgical treatment.
Let's Talk About It: Breast Cancer (What is Mindset and Does it Really Matter?)bkling
Your mindset is the way you make sense of the world around you. This lens influences the way you think, the way you feel, and how you might behave in certain situations. Let's talk about mindset myths that can get us into trouble and ways to cultivate a mindset to support your cancer survivorship in authentic ways. Let’s Talk About It!
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DECODING THE RISKS - ALCOHOL, TOBACCO & DRUGS.pdfDr Rachana Gujar
Introduction: Substance use education is crucial due to its prevalence and societal impact.
Alcohol Use: Immediate and long-term risks include impaired judgment, health issues, and social consequences.
Tobacco Use: Immediate effects include increased heart rate, while long-term risks encompass cancer and heart disease.
Drug Use: Risks vary depending on the drug type, including health and psychological implications.
Prevention Strategies: Education, healthy coping mechanisms, community support, and policies are vital in preventing substance use.
Harm Reduction Strategies: Safe use practices, medication-assisted treatment, and naloxone availability aim to reduce harm.
Seeking Help for Addiction: Recognizing signs, available treatments, support systems, and resources are essential for recovery.
Personal Stories: Real stories of recovery emphasize hope and resilience.
Interactive Q&A: Engage the audience and encourage discussion.
Conclusion: Recap key points and emphasize the importance of awareness, prevention, and seeking help.
Resources: Provide contact information and links for further support.
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LGBTQ+ Adults: Unique Opportunities and Inclusive Approaches to CareVITASAuthor
This webinar helps clinicians understand the unique healthcare needs of the LGBTQ+ community, primarily in relation to end-of-life care. Topics include social and cultural background and challenges, healthcare disparities, advanced care planning, and strategies for reaching the community and improving quality of care.
Unlocking the Secrets to Safe Patient Handling.pdfLift Ability
Furthermore, the time constraints and workload in healthcare settings can make it challenging for caregivers to prioritise safe patient handling Australia practices, leading to shortcuts and increased risks.
R3 Stem Cell Therapy: A New Hope for Women with Ovarian FailureR3 Stem Cell
Discover the groundbreaking advancements in stem cell therapy by R3 Stem Cell, offering new hope for women with ovarian failure. This innovative treatment aims to restore ovarian function, improve fertility, and enhance overall well-being, revolutionizing reproductive health for women worldwide.
Exploring the Benefits of Binaural Hearing: Why Two Hearing Aids Are Better T...Ear Solutions (ESPL)
Binaural hearing using two hearing aids instead of one offers numerous advantages, including improved sound localization, enhanced sound quality, better speech understanding in noise, reduced listening effort, and greater overall satisfaction. By leveraging the brain’s natural ability to process sound from both ears, binaural hearing aids provide a more balanced, clear, and comfortable hearing experience. If you or a loved one is considering hearing aids, consult with a hearing care professional at Ear Solutions hearing aid clinic in Mumbai to explore the benefits of binaural hearing and determine the best solution for your hearing needs. Embracing binaural hearing can lead to a richer, more engaging auditory experience and significantly improve your quality of life.
This particular slides consist of- what is hypotension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is the summary of hypotension:
Hypotension, or low blood pressure, is when the pressure of blood circulating in the body is lower than normal or expected. It's only a problem if it negatively impacts the body and causes symptoms. Normal blood pressure is usually between 90/60 mmHg and 120/80 mmHg, but pressures below 90/60 are generally considered hypotensive.
About this webinar: This talk will introduce what cancer rehabilitation is, where it fits into the cancer trajectory, and who can benefit from it. In addition, the current landscape of cancer rehabilitation in Canada will be discussed and the need for advocacy to increase access to this essential component of cancer care.
Letter to MREC - application to conduct studyAzreen Aj
Application to conduct study on research title 'Awareness and knowledge of oral cancer and precancer among dental outpatient in Klinik Pergigian Merlimau, Melaka'
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At Apollo Hospital, Lucknow, U.P., we provide specialized care for children experiencing dehydration and other symptoms. We also offer NICU & PICU Ambulance Facility Services. Consult our expert today for the best pediatric emergency care.
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International Cancer Survivors Day is celebrated during June, placing the spotlight not only on cancer survivors, but also their caregivers.
CANSA has compiled a list of tips and guidelines of support:
https://cansa.org.za/who-cares-for-cancer-patients-caregivers/
2. DR SARDAR SAJID MEHMOOD KHANDR SARDAR SAJID MEHMOOD KHAN
MBBS, MRCS (Ireland), FCPS (Ortho)MBBS, MRCS (Ireland), FCPS (Ortho)
SENIOR REGISTRAR, RIYADH CARE HOSPITALSENIOR REGISTRAR, RIYADH CARE HOSPITAL
3. OSTEOSARCOMAOSTEOSARCOMA
Osteosarcoma is primary malignant boneOsteosarcoma is primary malignant bone
forming tumorforming tumor
Common in young children and adolescents atCommon in young children and adolescents at
growing ends of bonesgrowing ends of bones
7. HIST0RYHIST0RY
An ancient disease present in Greek, EgyptianAn ancient disease present in Greek, Egyptian
& Indian literature.& Indian literature.
SARCOMA derived from Greek roots, meansSARCOMA derived from Greek roots, means
fleshy excrescence, used first time by Englishfleshy excrescence, used first time by English
Surgeon, JOHN ABERNATHY in 1804.Surgeon, JOHN ABERNATHY in 1804.
OSTEOSARCOMA, first time used by FrenchOSTEOSARCOMA, first time used by French
Surgeon, Alexis Boyer in 1805Surgeon, Alexis Boyer in 1805
(PERSONEL SURGEON TO NAPOLEON)(PERSONEL SURGEON TO NAPOLEON)
8. HISTORYHISTORY
1847,BORON GUILLAUME DUPUYTREN1847,BORON GUILLAUME DUPUYTREN
demonstrated gross pathologic appearance asdemonstrated gross pathologic appearance as
Osteosarcoma is a true cancerous degenerationOsteosarcoma is a true cancerous degeneration
of bone, manifest itself in the form of white orof bone, manifest itself in the form of white or
reddish mass, lardaceous and firm at an earlyreddish mass, lardaceous and firm at an early
stage of disease but presenting at latter stagestage of disease but presenting at latter stage
points of softening, cerebriform matter,points of softening, cerebriform matter,
extravasating blood, and white or strawextravasating blood, and white or straw
colored fluid of viscid consistence in itscolored fluid of viscid consistence in its
interior.interior.
9. HISTORYHISTORY
1900,VITTORIO PUTTI,SCAGLIETTI &1900,VITTORIO PUTTI,SCAGLIETTI &
COMPANACCI from ITLAY shaped treatment forCOMPANACCI from ITLAY shaped treatment for
Bone Tumor.Bone Tumor.
1921,ERNEST AMROY CODMAN &JAMES1921,ERNEST AMROY CODMAN &JAMES
EWING created registry for Bone Sarcoma.EWING created registry for Bone Sarcoma.
1950,HENRY L.JAFFE,LOUIS LICTENSTEIN1950,HENRY L.JAFFE,LOUIS LICTENSTEIN
established all key histological criteria used toestablished all key histological criteria used to
diagnose most of Bone Tumors.diagnose most of Bone Tumors.
10. HIST0RYHIST0RY
1970,NORMAN JAFFE, introduced1970,NORMAN JAFFE, introduced
Chemotherapeutic agents such asChemotherapeutic agents such as
METHOTREXATE & ADRIAMYCIN,METHOTREXATE & ADRIAMYCIN,
dramatically improved the treatment ofdramatically improved the treatment of
Osteosarcoma through their ability to treatOsteosarcoma through their ability to treat
Micro metastasis.Micro metastasis.
1976,ROSEN introduced Custom made1976,ROSEN introduced Custom made
Prosthesis.Prosthesis.
13. INCIDENCEINCIDENCE
Sixth leading cancer under age of 15Sixth leading cancer under age of 15
In USA 400 cases per Year.In USA 400 cases per Year.
(4.8 per Million <20 Y ),(4.8 per Million <20 Y ),
More common in black AmericansMore common in black Americans
Male 5.2 per Million per year,Male 5.2 per Million per year,
Female 4.2 per Million per yearFemale 4.2 per Million per year
Rare below 5 year(0.5 per Million per year)Rare below 5 year(0.5 per Million per year)
300 die in each year300 die in each year
22NDND
peak in incidence in Elderly, associated with Pagetpeak in incidence in Elderly, associated with Paget
disease, Bone infarct, or Post radiation.disease, Bone infarct, or Post radiation.
26. ETIOLOGYETIOLOGY
Exact cause is unknownExact cause is unknown
Risk factorsRisk factors
1;Rapid Bone Growth1;Rapid Bone Growth
2;2; RadiationRadiation
3;Genetic predisposition3;Genetic predisposition
27. ETIOLOGYETIOLOGY
Bone Dysplasias, including Paget Disease,
Fibrous Dysplasias, Enchondromatosis,
Hereditary Multiple Exostosis &
Retinoblastoma (Germ Line)
*Mutations in Tumor Suppressor Genes,P53
& Rb have major role in Osteosarcoma
development
30. PATHOLOGYPATHOLOGY
Localized at Metaphyseal ends of Long BonesLocalized at Metaphyseal ends of Long Bones
Solid, Hard, Irregular due to Tumor Spicules ofSolid, Hard, Irregular due to Tumor Spicules of
Calcified Bone, Surrounding Tissue infiltratedCalcified Bone, Surrounding Tissue infiltrated
31. PATHOLOGYPATHOLOGY
Microscopically, Tumor Cells are Pleomorphic,someMicroscopically, Tumor Cells are Pleomorphic,some
are Giant with numerous Mitosis, producingare Giant with numerous Mitosis, producing
Amorphous, Eosinophilic Osteoid with or withoutAmorphous, Eosinophilic Osteoid with or without
central Calcification.central Calcification.
46. CLINICAL PRESENTATIONCLINICAL PRESENTATION
Bone PainBone Pain
Most Common Symptom present atMost Common Symptom present at
night or afternight or after
exerciseexercise
SwellingSwelling
Decreased Joint MotionDecreased Joint Motion
Pathological FracturePathological Fracture
Respiratory symptomsRespiratory symptoms
Due to MetastasisDue to Metastasis
47. CLINICAL SIGNSCLINICAL SIGNS
MassMass
Palpable mass may or may not present,Palpable mass may or may not present,
may be warm & tender, firm to hard, increasedmay be warm & tender, firm to hard, increased
skin vascularity over mass.skin vascularity over mass.
Decreased Joint MobilityDecreased Joint Mobility
LymphadenopathyLymphadenopathy
Respiratory FindingsRespiratory Findings
48.
49.
50. DIAGNOSTIC TOOLSDIAGNOSTIC TOOLS
Plain X-RayPlain X-Ray
Total Body ScanTotal Body Scan
MRI of Primary TumorMRI of Primary Tumor
CT Scan LungCT Scan Lung
BiopsyBiopsy
Laboratory StudiesLaboratory Studies
79. PROGNOSISPROGNOSIS
5 year Survival ranges from 60% to 85%5 year Survival ranges from 60% to 85%
60 to 65% Treated 5 years ago (2000) will60 to 65% Treated 5 years ago (2000) will
be alive todaybe alive today
Stage 1 Osteosarcoma has goodStage 1 Osteosarcoma has good
prognosis >90% just requiresprognosis >90% just requires
SurgerySurgery
80. PROGNOSISPROGNOSIS
Stage 11b Prognosis dependsStage 11b Prognosis depends
1.1. Site of Tumor (worse for Axial Skeletal)Site of Tumor (worse for Axial Skeletal)
2.2. Size of Tumor Mass in cmSize of Tumor Mass in cm
3.3. Degree of necrosis from NeoadjuvantDegree of necrosis from Neoadjuvant
ChemotherapyChemotherapy
81. PROGNOSISPROGNOSIS
Stage 111 with Lung Metastasis,Stage 111 with Lung Metastasis,
overall Prognosis is 30% depends onoverall Prognosis is 30% depends on
1.1. Resectability of primary tumor& LungResectability of primary tumor& Lung
NodulesNodules
2.2. Degree of Necrosis of primary TumorDegree of Necrosis of primary Tumor
3.3. Number of MetastasisNumber of Metastasis
4.4. Duration of development of MetastasisDuration of development of Metastasis