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05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
1
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
2
HEART
DR M.SIKANDER GHAYAS KHAN
MBBS, MS-SLP, PGH, Ph.D.
Assistant Professor,
Riphah international University Lahore
Pakistan.
dr.sikander05@gmail.com
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
3
LOCATION
Middle
mediastinum
1/3 lies on the rt &
2/3 on the lt
Second to fifth rib
Rt sternal border
to lt mid clavicular
line
Conical shaped.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
4
MEDIASTINUM
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
5
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
6
HEART
THE HEART IS PART OF THE
CARDIOVASCULAR SYSTEM.
THE FUNCTION OF THE HEART
IS TO PUMP BLOOD.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
7
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
8
HEART
The heart is
enclosed in a double
walled sac called the
pericardium.
The superficial
layer is the fibrous
pericardium, and the
deep layer is the
serous pericardium.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
9
PERICARDIUM
Fibrous layer
Tough external fibrous layer
pericardiophrenic ligament
sternopericardiac ligament
It fuses with adventitia of all the great
vessels
The parietal layer lines the inner
surface of the fibrous pericardium.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
10
PERICARDIUM
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
11
PERICARDIUM
FUNCTIONS OF THE FIBROUS
PERICARDIUM
1. PROTECTS THE HEART.
2. FIX THE HEART WITHIN THE THORAX.
3. PREVENTS OVERFILLING OF THE
HEART.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
12
PERICARDIUM
The serous
pericardium, a thin
slippery serous
membrane, is
composed of two
layers, the parietal
layer and the visceral
layer or epicardium.
Between the two
layers is the
pericardial cavity.
This cavity contains a
film of serous fluid.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
13
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
14
Pericardial Sinuses
Oblique
sinus
On the posterior
surface of the heart,
the reflection of the
serous pericardium
around the large
veins forms a recess.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
15
Transverse
sinus,
Reflection of
serous pericardium
around the aorta
and pulmonary
trunk and the
reflection around
the large veins..
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
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05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
17
Nerve Supply of
the Pericardium
The fibrous
pericardium and the
parietal layer of the
serous pericardium are
supplied by the phrenic
nerves.
The visceral layer of
the serous pericardium
is innervated by
branches of the
sympathetic trunks
and the vagus nerves.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
18
Surfaces of the Heart
The sternocostal
The diaphragmatic
surface
The base
The
sternocostal
 right atrium and
the right ventricle,05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
19
The diaphragmatic
surface
right and left
ventricles separated
by the posterior
interventricular
groove. The inferior
surface of the right
atrium, into which the
inferior vena cava
opens, also forms part
of this surface.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
20
The base is
formed mainly by the
left atrium, into which
open the four
pulmonary veins .
The base of the
heart lies opposite
the apex
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
21
The apex of the
heart, formed by the
left ventricle, is
directed downward,
forward, and to the
left .
It lies at the level
of the fifth left
intercostal space, 3.5
in. (9 cm) from the
midline.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
22
BORDERS OF THE HEART
The four borders of the heart are the
Right border
Left border
Inferior border
Superior border
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
23
Right border
(slightly convex),
Formed by the
right atrium and
extending between
the SVC and the
IVC.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
24
Left border
(oblique), Formed
mainly by the left
ventricle and slightly
by the left auricle.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
25
Inferior border
(nearly horizontal),
Formed mainly by
the right ventricle
and only slightly by
the left ventricle.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
26
Superior border, Formed by the
Right and left atria
Auricles in anterior view
The ascending aorta
Pulmonary trunk emerge from the
superior border
The SVC
Transverse pericardial sinus.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
27
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
28
Cardiac skeleton
Collection of dense,
fibrous connective tissue in
the form of four rings.
Two surround the
atrioventricular orifices,
 And two surround the
aortic orifice and opening of
the pulmonary trunks.
 Anulus fibrosus.
The interconnecting areas
include:
right fibrous trigone,
left fibrous trigone,
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
29
Helps maintain the integrity of the
openings it surrounds
 Provides attachment for the cusps.
Separates the atrial musculature from the
ventricular musculature.
Isolates the atria from the ventricles.
The atrioventricular bundle is the single
connection between these two groups of
myocardium.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
30
Cardiac chambers
Interatrial,
interventricular, and
atrioventricular septa
separate the four
chambers of the
heart
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
31
RIGHT ATRIUM
The human heart
consists of 2 atria, right
and left.
The atrium has two
basic parts. The
smooth walled posterior
and the anterior portion
with ridges formed from
pectinate muscles.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
32
Openings:
Superior vena cava.
Inferior vena cava.
Tricuspid valve divides
the right atrium from the
right ventricle.
Coronary sinus.
Small cardinal veins.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
33
Additional
strictures
Fossa ovalis
Limbus of ovalis
Crista terminalis
Sulcus terminalis
SA node
AV node
Inter nodal
pathways05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
34
Right ventricle
Anatomic position.
Infundibulum.
Trabeculae
carneae
Papillary muscles.
The chordae
tendineae which
connect to the free
edges of the cusps
of the tricuspid valve.
Moderator band.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
35
Tricuspid valve
The naming of the three cusps, the
anterior, septal, and posterior cusps,
The base of each cusp surrounds the
fibrous ring. This fibrous ring helps to
maintain the shape of the opening. The
cusps are continuous with each other near
their bases at sites termed commissures.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
36
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
37
Pulmonary valve ,
 The cusps are named
the left, right and anterior
semilunar cusps
Nodule of the semilunar
cusp The free superior
edge of each cusp has a
middle, thickened portion,
Lunule of the semilunar
cusp thin lateral portion
Pulmonary sinuses.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
38
LEFT ATRIUM
The posterior half receives the four
pulmonary veins. It has smooth walls .
The anterior half is continuous with the left
auricle. It contains musculi pectinati.
The interatrial septum is part of the
anterior wall of the left atrium.
Depression in the septum is the valve of
the foramen ovale.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
39
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
40
LEFT VENTRICALE
Anterior to the left atrium.
 It contributes to the anterior and
diaphragmatic surfaces of the heart, and
forms the apex.
Conical, longer and thickest than the right
ventricle.
The outflow tract (the aortic vestibule) is
posterior to the infundibulum of the right
ventricle, has smooth.
The trabeculae carneae in the left
ventricle are fine.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
41
Papillary muscles, together with chordae
tendineae. Two papillary muscles, the anterior
and posterior, are larger than those of the right
ventricle .
Posterior to the right ventricle.
Two parts of Septum:
Muscular part, and Membranous part.
The muscular part is thick .
Membranous part is the thin.
 A third part present above the septal cusp of the
tricuspid valve between the left ventricle and
right atrium.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
42
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
43
Mitral valve
Mitral valve present posterior, right side
of the superior part of the left ventricle.
 Also called bicuspid valve because it has
two cusps, the anterior and posterior
cusps.
The bases of the cusps are secured to a
fibrous ring surrounding the opening, and
the cusps are continuous with each other
at the commissures.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
44
ATRIOVENTRICULAR VALVES
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
45
ATRIOVENTRICULAR VALVES
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
46
Aortic valve
The opening from the left ventricle into the
aorta is closed by the aortic valve.
This valve is similar in structure to the
pulmonary valve.
Between the semilunar cusps and the wall
of the ascending aorta are pocket-like
sinuses-the right, left, and posterior
aortic sinuses.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
47
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
48
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
49
VENTRICLES
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
50
VASCULATURE OF THE HEART
Vessels are embedded in the fat just deep
to the epicardium
Vessels receive both sympathetic &
parasympathetic supply
Coronary arteries are the first branches
from aorta
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
51
Arterial Supply of the Heart
Right and
Left coronary
The right coronary artery arises from the
anterior aortic sinus of the ascending aorta and runs
forward between the pulmonary trunk and the right
auricle .
It descends almost vertically in the right atrioventricular
groove, and at the inferior border of the heart it
continues posteriorly along the atrioventricular groove
to Anatomose with the left coronary artery in the
posterior interventricular groove
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
52
The following branches from the right
coronary artery supply the
Right atrium
Right ventricle
Parts of the left atrium
Left ventricle
Atrioventricular septum.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
53
Branches
The right conus artery anterior surface of the
pulmonary conus (infundibulum of the right
ventricle) and
 upper part of the anterior wall of the right
ventricle.
The anterior ventricular branches supply the
anterior surface of the right ventricle.
The marginal branch is the largest and runs
along the lower margin of the costal surface to
reach the apex.
The posterior ventricular branches supply the
diaphragmatic surface of the right ventricle.05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
54
The posterior interventricular It gives off branches to
the right and left ventricles, including its inferior wall.
posterior part of the ventricular septum but not to the
apical part, which receives its supply from the anterior
interventricular branch of the left coronary artery.
atrioventricular node A large septal branch supplies the
AV node. In 10% of individuals the posterior
interventricular artery is replaced by a branch from the
left coronary artery.
The atrial branches supply the anterior and lateral
surfaces of the right atrium. One branch supplies the
posterior surface of both the right and left atria.
 The artery of the sinuatrial node supplies the node and
the right and left atria; in 35% of individuals it arises from
the left coronary artery.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
55
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
56
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
57
The left coronary artery, which is usually
larger than the right coronary artery,
 supplies the greater part of the left atrium,
 left ventricle, and ventricular septum.
It arises from the left posterior aortic sinus of the
ascending aorta and passes forward between
the pulmonary trunk and the left auricle .It then
enters the atrioventricular groove and divides
into an anterior interventricular branch and a
circumflex branch.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
58
Branches
The anterior interventricular (descending) branch
runs downward in the anterior interventricular groove to
the apex of the heart .In most individuals it then passes
around the apex of the heart to enter the posterior
interventricular groove and anastomoses with the
terminal branches of the right coronary artery. In one
third of individuals it ends at the apex of the heart. The
anterior interventricular branch supplies the right and left
ventricles with numerous branches that also supply the
anterior part of the ventricular septum. One of these
ventricular branches (left diagonal artery) may arise
directly from the trunk of the left coronary artery. A small
left conus artery supplies the pulmonary conus
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
59
Branches
The circumflex artery is the same size as the
anteriorinterventricular artery .It winds around
the left margin of the heart in the atrioventricular
groove. A left marginal artery is a large branch
that supplies the left margin of the left ventricle
down to the apex.
Anterior ventricular and posterior ventricular
branches supply the left ventricle.
Atrial branches supply the left atrium.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
60
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
61
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
62
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
63
VENOUS DRAINAGE OF HEART
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
64
Venous Drainage of the Heart
Most blood from the heart wall drains into the
right atrium through the coronary sinus .which
lies in the posterior part of the atrioventricular
groove and is a continuation of the great
cardiac vein. It opens into the right atrium to the
left of the inferior vena cava. The small and
middle cardiac veins are tributaries of the
coronary sinus. The remainder of the blood is
returned to the right atrium by the anterior
cardiac vein and by small veins that open
directly into the heart chambers.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
65
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
66
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
67
MI & BYPASS GRAFTING
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
68
CONDUCTING SYSTEM OF
HEART
 Components
Sinuatrial node
Internodl pathway
Atrioventricular node
Atrioventricular bundle
Rt bundle branch
Lt bundle branch
Perkunji fibres
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
69
CONDUCTING SYSTEM
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
70
CONDUCTING SYSTEM OF
HEART
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
71
Nerve Supply of the Heart
 The heart is innervated by sympathetic
and parasympathetic fibers of the
autonomic nervous system via the
cardiac plexuses situated below the arch
of the aorta. The sympathetic supply
arises from the cervical and upper
thoracic portions of the sympathetic
trunks, and the parasympathetic supply
comes from the vagus nerves.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
72
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
73
 HISTOLOGY OF HEART
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
74
HEART WALL
THE HEART WALL CONSISTS OF 3
LAYERS
1. EPICARDIUM
2. MYOCARDIUM
3. ENDOCARDIUM
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
75
Epicardium
Epicardium is a dense sheet of fibrocollagenous
tissue F which also contains elastic fibres.
 Mesothelial cells Me responsible for secretion of
lubricating fluid.
large branch of the coronary artery CA, with a
smaller branch penetrating the myocardium M.
Adipose tissue A. Micrograph (b) shows the
appearance of the epicardium over most of the
heart surface where the fibrocollagenous layer lies
directly on the myocardium without adipose tissue.
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
76
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
77
Myocardium
longitudinal section
cardiac muscle fibres form
an interconnecting network,
joined to each other by
intercalated discs D,
central nuclei and
regular cytoplasmic
striations.
Extensive capillary
network C between the
myocardial fibres
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
78
Endocardium
The endocardium has
a surface layer of
flattened endothelial
cells E
Supported by a
fibrous layer F,
containing variable
amounts of elastic
tissue, which merges
with the collagen fibres
surrounding adjacent
cardiac muscle M and
the larger Purkinje
fibres P
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
79
THANKS FOR ATTENTION
05/17/16 Dr.M.Sikander Ghayas Khan
Riphah international University Lahore Pakistan
80

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Heart

  • 1. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 1
  • 2. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 2
  • 3. HEART DR M.SIKANDER GHAYAS KHAN MBBS, MS-SLP, PGH, Ph.D. Assistant Professor, Riphah international University Lahore Pakistan. dr.sikander05@gmail.com 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 3
  • 4. LOCATION Middle mediastinum 1/3 lies on the rt & 2/3 on the lt Second to fifth rib Rt sternal border to lt mid clavicular line Conical shaped.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 4
  • 5. MEDIASTINUM 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 5
  • 6. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 6
  • 7. HEART THE HEART IS PART OF THE CARDIOVASCULAR SYSTEM. THE FUNCTION OF THE HEART IS TO PUMP BLOOD. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 7
  • 8. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 8
  • 9. HEART The heart is enclosed in a double walled sac called the pericardium. The superficial layer is the fibrous pericardium, and the deep layer is the serous pericardium.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 9
  • 10. PERICARDIUM Fibrous layer Tough external fibrous layer pericardiophrenic ligament sternopericardiac ligament It fuses with adventitia of all the great vessels The parietal layer lines the inner surface of the fibrous pericardium.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 10
  • 11. PERICARDIUM 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 11
  • 12. PERICARDIUM FUNCTIONS OF THE FIBROUS PERICARDIUM 1. PROTECTS THE HEART. 2. FIX THE HEART WITHIN THE THORAX. 3. PREVENTS OVERFILLING OF THE HEART. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 12
  • 13. PERICARDIUM The serous pericardium, a thin slippery serous membrane, is composed of two layers, the parietal layer and the visceral layer or epicardium. Between the two layers is the pericardial cavity. This cavity contains a film of serous fluid.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 13
  • 14. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 14
  • 15. Pericardial Sinuses Oblique sinus On the posterior surface of the heart, the reflection of the serous pericardium around the large veins forms a recess. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 15
  • 16. Transverse sinus, Reflection of serous pericardium around the aorta and pulmonary trunk and the reflection around the large veins.. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 16
  • 17. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 17
  • 18. Nerve Supply of the Pericardium The fibrous pericardium and the parietal layer of the serous pericardium are supplied by the phrenic nerves. The visceral layer of the serous pericardium is innervated by branches of the sympathetic trunks and the vagus nerves. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 18
  • 19. Surfaces of the Heart The sternocostal The diaphragmatic surface The base The sternocostal  right atrium and the right ventricle,05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 19
  • 20. The diaphragmatic surface right and left ventricles separated by the posterior interventricular groove. The inferior surface of the right atrium, into which the inferior vena cava opens, also forms part of this surface. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 20
  • 21. The base is formed mainly by the left atrium, into which open the four pulmonary veins . The base of the heart lies opposite the apex 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 21
  • 22. The apex of the heart, formed by the left ventricle, is directed downward, forward, and to the left . It lies at the level of the fifth left intercostal space, 3.5 in. (9 cm) from the midline.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 22
  • 23. BORDERS OF THE HEART The four borders of the heart are the Right border Left border Inferior border Superior border 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 23
  • 24. Right border (slightly convex), Formed by the right atrium and extending between the SVC and the IVC. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 24
  • 25. Left border (oblique), Formed mainly by the left ventricle and slightly by the left auricle. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 25
  • 26. Inferior border (nearly horizontal), Formed mainly by the right ventricle and only slightly by the left ventricle. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 26
  • 27. Superior border, Formed by the Right and left atria Auricles in anterior view The ascending aorta Pulmonary trunk emerge from the superior border The SVC Transverse pericardial sinus. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 27
  • 28. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 28
  • 29. Cardiac skeleton Collection of dense, fibrous connective tissue in the form of four rings. Two surround the atrioventricular orifices,  And two surround the aortic orifice and opening of the pulmonary trunks.  Anulus fibrosus. The interconnecting areas include: right fibrous trigone, left fibrous trigone, 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 29
  • 30. Helps maintain the integrity of the openings it surrounds  Provides attachment for the cusps. Separates the atrial musculature from the ventricular musculature. Isolates the atria from the ventricles. The atrioventricular bundle is the single connection between these two groups of myocardium. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 30
  • 31. Cardiac chambers Interatrial, interventricular, and atrioventricular septa separate the four chambers of the heart 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 31
  • 32. RIGHT ATRIUM The human heart consists of 2 atria, right and left. The atrium has two basic parts. The smooth walled posterior and the anterior portion with ridges formed from pectinate muscles. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 32
  • 33. Openings: Superior vena cava. Inferior vena cava. Tricuspid valve divides the right atrium from the right ventricle. Coronary sinus. Small cardinal veins. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 33
  • 34. Additional strictures Fossa ovalis Limbus of ovalis Crista terminalis Sulcus terminalis SA node AV node Inter nodal pathways05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 34
  • 35. Right ventricle Anatomic position. Infundibulum. Trabeculae carneae Papillary muscles. The chordae tendineae which connect to the free edges of the cusps of the tricuspid valve. Moderator band. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 35
  • 36. Tricuspid valve The naming of the three cusps, the anterior, septal, and posterior cusps, The base of each cusp surrounds the fibrous ring. This fibrous ring helps to maintain the shape of the opening. The cusps are continuous with each other near their bases at sites termed commissures. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 36
  • 37. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 37
  • 38. Pulmonary valve ,  The cusps are named the left, right and anterior semilunar cusps Nodule of the semilunar cusp The free superior edge of each cusp has a middle, thickened portion, Lunule of the semilunar cusp thin lateral portion Pulmonary sinuses. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 38
  • 39. LEFT ATRIUM The posterior half receives the four pulmonary veins. It has smooth walls . The anterior half is continuous with the left auricle. It contains musculi pectinati. The interatrial septum is part of the anterior wall of the left atrium. Depression in the septum is the valve of the foramen ovale. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 39
  • 40. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 40
  • 41. LEFT VENTRICALE Anterior to the left atrium.  It contributes to the anterior and diaphragmatic surfaces of the heart, and forms the apex. Conical, longer and thickest than the right ventricle. The outflow tract (the aortic vestibule) is posterior to the infundibulum of the right ventricle, has smooth. The trabeculae carneae in the left ventricle are fine.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 41
  • 42. Papillary muscles, together with chordae tendineae. Two papillary muscles, the anterior and posterior, are larger than those of the right ventricle . Posterior to the right ventricle. Two parts of Septum: Muscular part, and Membranous part. The muscular part is thick . Membranous part is the thin.  A third part present above the septal cusp of the tricuspid valve between the left ventricle and right atrium.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 42
  • 43. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 43
  • 44. Mitral valve Mitral valve present posterior, right side of the superior part of the left ventricle.  Also called bicuspid valve because it has two cusps, the anterior and posterior cusps. The bases of the cusps are secured to a fibrous ring surrounding the opening, and the cusps are continuous with each other at the commissures. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 44
  • 45. ATRIOVENTRICULAR VALVES 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 45
  • 46. ATRIOVENTRICULAR VALVES 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 46
  • 47. Aortic valve The opening from the left ventricle into the aorta is closed by the aortic valve. This valve is similar in structure to the pulmonary valve. Between the semilunar cusps and the wall of the ascending aorta are pocket-like sinuses-the right, left, and posterior aortic sinuses. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 47
  • 48. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 48
  • 49. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 49
  • 50. VENTRICLES 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 50
  • 51. VASCULATURE OF THE HEART Vessels are embedded in the fat just deep to the epicardium Vessels receive both sympathetic & parasympathetic supply Coronary arteries are the first branches from aorta 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 51
  • 52. Arterial Supply of the Heart Right and Left coronary The right coronary artery arises from the anterior aortic sinus of the ascending aorta and runs forward between the pulmonary trunk and the right auricle . It descends almost vertically in the right atrioventricular groove, and at the inferior border of the heart it continues posteriorly along the atrioventricular groove to Anatomose with the left coronary artery in the posterior interventricular groove 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 52
  • 53. The following branches from the right coronary artery supply the Right atrium Right ventricle Parts of the left atrium Left ventricle Atrioventricular septum. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 53
  • 54. Branches The right conus artery anterior surface of the pulmonary conus (infundibulum of the right ventricle) and  upper part of the anterior wall of the right ventricle. The anterior ventricular branches supply the anterior surface of the right ventricle. The marginal branch is the largest and runs along the lower margin of the costal surface to reach the apex. The posterior ventricular branches supply the diaphragmatic surface of the right ventricle.05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 54
  • 55. The posterior interventricular It gives off branches to the right and left ventricles, including its inferior wall. posterior part of the ventricular septum but not to the apical part, which receives its supply from the anterior interventricular branch of the left coronary artery. atrioventricular node A large septal branch supplies the AV node. In 10% of individuals the posterior interventricular artery is replaced by a branch from the left coronary artery. The atrial branches supply the anterior and lateral surfaces of the right atrium. One branch supplies the posterior surface of both the right and left atria.  The artery of the sinuatrial node supplies the node and the right and left atria; in 35% of individuals it arises from the left coronary artery. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 55
  • 56. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 56
  • 57. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 57
  • 58. The left coronary artery, which is usually larger than the right coronary artery,  supplies the greater part of the left atrium,  left ventricle, and ventricular septum. It arises from the left posterior aortic sinus of the ascending aorta and passes forward between the pulmonary trunk and the left auricle .It then enters the atrioventricular groove and divides into an anterior interventricular branch and a circumflex branch. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 58
  • 59. Branches The anterior interventricular (descending) branch runs downward in the anterior interventricular groove to the apex of the heart .In most individuals it then passes around the apex of the heart to enter the posterior interventricular groove and anastomoses with the terminal branches of the right coronary artery. In one third of individuals it ends at the apex of the heart. The anterior interventricular branch supplies the right and left ventricles with numerous branches that also supply the anterior part of the ventricular septum. One of these ventricular branches (left diagonal artery) may arise directly from the trunk of the left coronary artery. A small left conus artery supplies the pulmonary conus 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 59
  • 60. Branches The circumflex artery is the same size as the anteriorinterventricular artery .It winds around the left margin of the heart in the atrioventricular groove. A left marginal artery is a large branch that supplies the left margin of the left ventricle down to the apex. Anterior ventricular and posterior ventricular branches supply the left ventricle. Atrial branches supply the left atrium. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 60
  • 61. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 61
  • 62. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 62
  • 63. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 63
  • 64. VENOUS DRAINAGE OF HEART 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 64
  • 65. Venous Drainage of the Heart Most blood from the heart wall drains into the right atrium through the coronary sinus .which lies in the posterior part of the atrioventricular groove and is a continuation of the great cardiac vein. It opens into the right atrium to the left of the inferior vena cava. The small and middle cardiac veins are tributaries of the coronary sinus. The remainder of the blood is returned to the right atrium by the anterior cardiac vein and by small veins that open directly into the heart chambers. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 65
  • 66. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 66
  • 67. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 67
  • 68. MI & BYPASS GRAFTING 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 68
  • 69. CONDUCTING SYSTEM OF HEART  Components Sinuatrial node Internodl pathway Atrioventricular node Atrioventricular bundle Rt bundle branch Lt bundle branch Perkunji fibres 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 69
  • 70. CONDUCTING SYSTEM 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 70
  • 71. CONDUCTING SYSTEM OF HEART 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 71
  • 72. Nerve Supply of the Heart  The heart is innervated by sympathetic and parasympathetic fibers of the autonomic nervous system via the cardiac plexuses situated below the arch of the aorta. The sympathetic supply arises from the cervical and upper thoracic portions of the sympathetic trunks, and the parasympathetic supply comes from the vagus nerves. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 72
  • 73. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 73
  • 74.  HISTOLOGY OF HEART 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 74
  • 75. HEART WALL THE HEART WALL CONSISTS OF 3 LAYERS 1. EPICARDIUM 2. MYOCARDIUM 3. ENDOCARDIUM 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 75
  • 76. Epicardium Epicardium is a dense sheet of fibrocollagenous tissue F which also contains elastic fibres.  Mesothelial cells Me responsible for secretion of lubricating fluid. large branch of the coronary artery CA, with a smaller branch penetrating the myocardium M. Adipose tissue A. Micrograph (b) shows the appearance of the epicardium over most of the heart surface where the fibrocollagenous layer lies directly on the myocardium without adipose tissue. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 76
  • 77. 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 77
  • 78. Myocardium longitudinal section cardiac muscle fibres form an interconnecting network, joined to each other by intercalated discs D, central nuclei and regular cytoplasmic striations. Extensive capillary network C between the myocardial fibres 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 78
  • 79. Endocardium The endocardium has a surface layer of flattened endothelial cells E Supported by a fibrous layer F, containing variable amounts of elastic tissue, which merges with the collagen fibres surrounding adjacent cardiac muscle M and the larger Purkinje fibres P 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 79
  • 80. THANKS FOR ATTENTION 05/17/16 Dr.M.Sikander Ghayas Khan Riphah international University Lahore Pakistan 80