This document discusses open research methodologies and initiatives. It defines open science as research that is verifiable, repeatable, extensible, and accessible. Open science involves making intellectual work and processes publicly visible through open access journals, machine readable formats, open peer review, and permissive licensing of content and data. The challenges of open science include issues around ideas being stolen, being wrong, and lack of specialization. The document advocates keeping a research blog, posting data online, and using open access sources to advance open science goals of knowledge sharing and reusability.