Open PHACTS provides a single access point for integrating multiple biomedical data resources. It has transitioned from an EU project to the Open PHACTS Foundation to sustain the platform long-term. Challenges included addressing licensing issues across different data sources and enabling maximum dissemination. Usage has grown to over 500 million queries. The Foundation is pursuing collaboration, grants, and industry partnerships to support ongoing development and new projects. It welcomes contributions to improve services and develop new data and workflows.