The document discusses BioApp Creator, a tool being developed by Insightomics to empower researchers to create their own interactive bioinformatics apps (BioApps) without coding. It aims to scale up the ecosystem into a global bioinformatics app marketplace and lower barriers to innovation in life sciences R&D by making researchers more autonomous. BioApp Creator builds on Insightomics' existing platform which blends visualizations and machine learning in a cloud-based environment. It addresses challenges like increasing the number of available apps and researchers' autonomy by allowing them to visually design BioApps that integrate with underlying methods.

1. Pedro Castro
Co-founder & CTO
BioApp Creator
Pistoia Alliance President's Startup Challenge 2016

2. Data Analysis Bottleneck
Pharma and Biotech increasingly combine omics and clinical data in their
R&D efforts.
The bottleneck in life sciences R&D is shifting towards data analysis.
Making sense of large volumes of heterogeneous data is a significant
problem.
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3. Market Situation
3
Existing bioinformatics tools are, in general, complex to use. Too
technical, unwieldy and not built for usability. Steep learning curve.
A large part still focuses on data acquisition, storage, search or simple
analyses. Lack of tools offering analysis integrated with interactive
visualizations － Visual Analytics.
Overdispersion of software － multiple implementations hinder
reproducibility.
Overdispersion of expertise － many different problems to solve, hard to
know which approach solves the problem best.

4. Market Pain
4
Lack of productivity in a complex and large
bioinformatics application landscape.
Existing tools are a limiting factor to innovation.

5. The Insightomics Platform
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App platform for bioinformatics.
Blends interactive visualizations with state-of-the-art machine learning
and statistical methods in a big data platform.
Web-based, sits in the cloud and can also be deployed on-premises.
Promotes collaboration.
Engine for creating visually rich, intuitive, and interactive bioinformatics
apps － BioApps.

6. BioApps
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Exploratory data analysis
Streamlining data analysis services
Providing interactive reports
Publication of reproducible research

7. Are we there yet?
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BioApp development still requires coding skills.
Research needs and ideas change constantly.
Developers are unable to anticipate all research needs.
Which apps to implement?

8. Key Challenges
8
How to increase the coverage of apps
available to researchers?
How to increase researchers’ autonomy?

9. Our Proposed Solution – BioApp Creator
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Empower researchers to create their own BioApps.
Through a visual and user-friendly web interface, researchers will be able
to create BioApps with relevant functionality without coding.
Resulting BioApps are visualization-focused by nature, and integrate
transparently with underlying bioinformatics methods.
BioApp Creator is powered by the existing declarative and feature-rich
APIs provided by the Insightomics Platform.

10. BioApp Creator Goals
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Scale up the ecosystem into a
global bioinformatics app marketplace.
Empower researchers to become more autonomous,
thus lowering barriers to R&D innovation.

11. In conclusion...
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BioApp Creator is strongly aligned with this competition’s goals, as well
as with Pistoia Alliance’s mission.
Provides the R&D community with a Global Bioinformatics App
Marketplace, greatly improving the number and quality of tools available
to researchers.
Empowers researchers to become more autonomous and make better
use of their data, with visualization-driven BioApps.
Transforms R&D processes by offering new means to store, secure,
manage and analyse data in the cloud.
Lowers barriers to R&D innovation in the life sciences.

12. © 2016 Insightomics | www.insightomics.com | pedro@insightomics.com

13. © 2016 Insightomics | www.insightomics.com | pedro@insightomics.com

14. 14
Support Slides

15. Leadership
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José Caldas, PhD
Co-founder & CEO
José has an extensive expertise in
bioinformatics, statistics and machine
learning. His specialties include advanced
machine learning and data mining
algorithms, large-scale bioinformatics
applications and biological problems such
as biomarker discovery, drug repurposing,
meta-analysis, and information retrieval.
He is first author of multiple scientific
papers on applying state-of-the-art
computational approaches in a Big Data
context, in collaboration with leading
experts in the field. José holds a PhD in
bioinformatics from Aalto University in
Finland, and an MSc and a BSc in
software engineering from Instituto
Superior Técnico, University of Lisbon.
Pedro Castro, MSc
Co-founder & CTO
Pedro has wide experience in managing
and delivering consulting services to
companies across a number of industries,
including Life Sciences, Health Care,
Public Sector, Insurance and Tourism.
With a background in IT and management
consulting, as a supervisor at Deloitte, his
specialties include project management
and PMO, IT strategy, software
engineering and business process
optimization. Pedro holds an MSc and a
BSc in Software Engineering from
Instituto Superior Técnico, University of
Lisbon.
André Rocha, MSc
VP of Business Development
André has extensive experience in setting
up and scaling startups as well as defining
and implementing large-scale projects in a
wide range of sectors. He was part of the
initial founding team of ZALORA
Philippines, where he played a key role in
setting up operations, launching the product
and scaling it up to 15M+ of annualized
revenue. He was also the first Associate at
BCG Angola where he worked with some of
the countries' main players in the
Government, Banking and Oil & Gas
sectors, in projects with country-wide
impact. André holds a BSc in Economics
from Nova SBE, an MSc in International
Management from Bocconi University and
is currently an MBA candidate at Harvard
Business School.