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ONCOLOGY DISEASES
ZAHRA NEGZA TUL
G11
CANCER
A group of diseases
characterized by an –
Abnormal growth of cells –
Ability to invade adjacent
tissues and even distant
organs
CATEGORIES OF CANCER
• • Carcinoma – arise from epithelial cells lining internal surfaces of various organs
& from skin epithelium
• • Sarcoma- arise from mesodermal cells constituting various connective tissues
• • Lymphoma, myeloma & leukaemia- arise from cells of bone marrow & immune
systems
• • “Primary tumour” – cancer in the organ of origin
• • “Secondary tumour”- • cancer that has spread to regional lymph nodes and
distant organs
WORLD WIDE
• • 22.4 million living with cancer
• • 10 million diagnosed every year
• • 6 million deaths every year
INCIDENCE
Lung (12.3%)
Breast (10.4%)
Colorectal (9.3%)
MORTALITY
• Lung (17.4%)
• Stomach(10.4%)
• Liver(8.8%)
GENDER WISE (PERSON) DISTRIBUTION OF CANCER
Males (LSC)
• Lung
• Stomach
• Colorectal
Females (BCC)
• Breast
• Cervix
• Colorectal
TIME TRENDS
• 6th cause of death in the 1900s
• 2nd cause of death in 2000 because of:
• Increase in life expectancy
• Better & accurate diagnosis
• Increase in cigarette smoking
DISTRIBUTION DEVELOPED COUNTRIES:
• • lifestyle and dietary habits e.g. Ca lung, Ca breast, Ca colorectal Developing
countries: infective origin e.g. Ca Cervix, Ca Liver, Ca stomach
• • Ca stomach common in Japan, not in US
• • Ca Cervix more common in EAR, not in Japan
CAUSES OF CANCER
• I.Environmental factors
• Tobacco
• Alcohol: oesophageal ,liver cancer,rectal cancer
• Dietary factors: Smoked fish-stomach cancer, beef-bowel cancer,high fat diet-
breast cancer Also food additives & contaminants-suspicion as causative agents
Low fruit and vegetable intake
CANCER CAUSING DRUGS
• Fluoxetine and Paroxeti
• Ibrufen (50%)
• Aspirin (80%)
• Zantacne
• Losartan and Valsartan
• Propranolol
• . Sumatriptan.
• Tamoxifen.
• Epinephrine.
OTHER FACTORS
• Immunosuppressants agents
• Industrial emission
• Alfatoxin
• Asbestos cause lung cancer
• Genetic factors
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology
Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology

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Oncology ppt Zahra niegza tul Iuk ism the best ppt ever of Oncology

  • 2. CANCER A group of diseases characterized by an – Abnormal growth of cells – Ability to invade adjacent tissues and even distant organs
  • 3.
  • 4.
  • 5. CATEGORIES OF CANCER • • Carcinoma – arise from epithelial cells lining internal surfaces of various organs & from skin epithelium • • Sarcoma- arise from mesodermal cells constituting various connective tissues • • Lymphoma, myeloma & leukaemia- arise from cells of bone marrow & immune systems • • “Primary tumour” – cancer in the organ of origin • • “Secondary tumour”- • cancer that has spread to regional lymph nodes and distant organs
  • 6. WORLD WIDE • • 22.4 million living with cancer • • 10 million diagnosed every year • • 6 million deaths every year
  • 7. INCIDENCE Lung (12.3%) Breast (10.4%) Colorectal (9.3%) MORTALITY • Lung (17.4%) • Stomach(10.4%) • Liver(8.8%)
  • 8. GENDER WISE (PERSON) DISTRIBUTION OF CANCER Males (LSC) • Lung • Stomach • Colorectal Females (BCC) • Breast • Cervix • Colorectal
  • 9. TIME TRENDS • 6th cause of death in the 1900s • 2nd cause of death in 2000 because of: • Increase in life expectancy • Better & accurate diagnosis • Increase in cigarette smoking
  • 10. DISTRIBUTION DEVELOPED COUNTRIES: • • lifestyle and dietary habits e.g. Ca lung, Ca breast, Ca colorectal Developing countries: infective origin e.g. Ca Cervix, Ca Liver, Ca stomach • • Ca stomach common in Japan, not in US • • Ca Cervix more common in EAR, not in Japan
  • 11. CAUSES OF CANCER • I.Environmental factors • Tobacco • Alcohol: oesophageal ,liver cancer,rectal cancer • Dietary factors: Smoked fish-stomach cancer, beef-bowel cancer,high fat diet- breast cancer Also food additives & contaminants-suspicion as causative agents Low fruit and vegetable intake
  • 12.
  • 13.
  • 14. CANCER CAUSING DRUGS • Fluoxetine and Paroxeti • Ibrufen (50%) • Aspirin (80%) • Zantacne • Losartan and Valsartan • Propranolol • . Sumatriptan. • Tamoxifen. • Epinephrine.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21. OTHER FACTORS • Immunosuppressants agents • Industrial emission • Alfatoxin • Asbestos cause lung cancer • Genetic factors