OBSTRUCTED LABOR is an emergency that poses significant risk to the life of both mother and fetus. A condition usually associated with low socioeconomic status puts much burden on the fragile health care delivery in subsaharan Africa
Labour induction
Induction of labour
Guidelines on induction of labour
Guidelines on labour induction
induction of labour is not risk free
prostaglandins for induction of labour
Bishop score
Cervical ripening techniques
mechanical and pharmacological induction of labour
Post dates induction
options for cervical ripening
oral vs. vaginal misoprostol
advantages diadvantages and techniques for induction of labour
gynecology & obstetrics
Labour induction methods
review of guidelines for labour induction
Labour induction
Induction of labour
Guidelines on induction of labour
Guidelines on labour induction
induction of labour is not risk free
prostaglandins for induction of labour
Bishop score
Cervical ripening techniques
mechanical and pharmacological induction of labour
Post dates induction
options for cervical ripening
oral vs. vaginal misoprostol
advantages diadvantages and techniques for induction of labour
gynecology & obstetrics
Labour induction methods
review of guidelines for labour induction
A biophysical profile is a prenatal test which is used to check on a baby's well-being. The test combines the fetal heart rate monitoring (NST- Non Stress Test) and fetal ultrasound to evaluate a Fetal heart rate, movements, breathing, muscle tone and amniotic fluid level.
For more notes: Join Us on Telegram: https://t.me/OBGYN_Note_Book Or Facebook: https://www.facebook.com/obgyn.books
Slideshare: https://www.slideshare.net/bjlomsecond
Obstetrics and Gynecological Nursing
The PPT contains detailed information about Abnormal uterine action, its classifications, causes, sign and symptoms and management.
A biophysical profile is a prenatal test which is used to check on a baby's well-being. The test combines the fetal heart rate monitoring (NST- Non Stress Test) and fetal ultrasound to evaluate a Fetal heart rate, movements, breathing, muscle tone and amniotic fluid level.
For more notes: Join Us on Telegram: https://t.me/OBGYN_Note_Book Or Facebook: https://www.facebook.com/obgyn.books
Slideshare: https://www.slideshare.net/bjlomsecond
Obstetrics and Gynecological Nursing
The PPT contains detailed information about Abnormal uterine action, its classifications, causes, sign and symptoms and management.
The Importance of Identifying Sepsis in the Golden First HourHasan Arafat
A case of a patient who was missed while in early sepsis. It sheds light on the importance of sticking to the guidelines of management of sepsis and how it can protect patients from deteriorating.
This Case Presenataiton was presented in Central Presentation of Faridpur Medical College Hospital, in November 2019, by Dr. Faisal Abdullah, MBBS; who was an Intern Doctor of Department of Gynaecology and Obstetrics of FMCH.
A Case of Primigravida with 36 weeks of pregnancy with IUD with obstructed la...Faisal Abdullah
This case was presented on weekly seminar of Department of Gynaecology and Obstetrics ( Unit 1) of Faridpur Medical College Hospital, in October 2019, by Intern Doctor Dr. Faisal Abdullah.
Respiratory Failure is a common cause of death among hospitalized patients. The causes are many and serves as the final common pathway for most conditions
Severe malaria is an important cause of U-5 morbidity and mortality in malaria endemic areas like the subsaharan Africa particularly Nigeria which accounts for more than half of the burden on the continent.
It is a life threatening condition, a medical emergency requiring in-patient care. Early treatment curtails the dismal outcomes of this condition.
The most important preventive measures is use of insecticide treated mosquito nets in addition to environmental control, seasonal chemoprophylaxis and use of Malaria Vaccine.
The recent recommendations by the WHO is use of IV Artesunate or if unavailable, artemether and quinine followed by full course of ACTs. Other complications should be treated as required and those with life threatening complications should preferably be managed in the ICU.
An intensive care unit is one of the important divisions in the hospital setting. It is a building dedicated to the management of patients with life threatening conditions that can not be managed on the ward. A knowledge of the intensive care unit is of paramount importance to all healthcare providers.
Children are curious and tend to explore their surroundings. While doing so they may run, ingest, or inhale potentially harmful substances. Tens of thousands of cases of childhood poisoning are reported annually and some are associated with major morbidity and mortality.
Theatre design, one of the most critical steps in hospital construction. When wrongly designed and situated, poses a significant health hazard to both the patient and the environment.
A harmful practice that has lasted for ages. A traumatic experience to it's victims that portends non of the purported benefits. A global scourge with huge medical and PsychoSocial Implications. All efforts must be made to end this menace
Morbidity (from Latin morbidus: sick, unhealthy) refers to having a disease or a symptom of disease, or to the amount of disease within a population.
Any departure, subjective or objective from a state of physiological well being.
Morbidity also refers to medical problems caused by a treatment.
It is usually represented or estimated using prevalence or incidence.
Basic life support is a skill each and every human is expected to master. In a world full of accidents and rancour, the ability of a citizen to perform adequate cardiopulmonary resuscitation is paramount.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
MANAGEMENT OF ATRIOVENTRICULAR CONDUCTION BLOCK.pdfJim Jacob Roy
Cardiac conduction defects can occur due to various causes.
Atrioventricular conduction blocks ( AV blocks ) are classified into 3 types.
This document describes the acute management of AV block.
HOT NEW PRODUCT! BIG SALES FAST SHIPPING NOW FROM CHINA!! EU KU DB BK substit...GL Anaacs
Contact us if you are interested:
Email / Skype : kefaya1771@gmail.com
Threema: PXHY5PDH
New BATCH Ku !!! MUCH IN DEMAND FAST SALE EVERY BATCH HAPPY GOOD EFFECT BIG BATCH !
Contact me on Threema or skype to start big business!!
Hot-sale products:
NEW HOT EUTYLONE WHITE CRYSTAL!!
5cl-adba precursor (semi finished )
5cl-adba raw materials
ADBB precursor (semi finished )
ADBB raw materials
APVP powder
5fadb/4f-adb
Jwh018 / Jwh210
Eutylone crystal
Protonitazene (hydrochloride) CAS: 119276-01-6
Flubrotizolam CAS: 57801-95-3
Metonitazene CAS: 14680-51-4
Payment terms: Western Union,MoneyGram,Bitcoin or USDT.
Deliver Time: Usually 7-15days
Shipping method: FedEx, TNT, DHL,UPS etc.Our deliveries are 100% safe, fast, reliable and discreet.
Samples will be sent for your evaluation!If you are interested in, please contact me, let's talk details.
We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
3. History
PRESENTIG COMPLAINT
Labour pain of 24 hours duration
HISTORY OF PRESENTING COMPLAINT
Patient was apparently well until about 24 hours prior to
presentation when she developed lower abdominal pain of
gradual onset, associated increase in frequency.
6 hours later she noticed sudden gush of clear fluid from the
vagina which soaked her wrapper and non foul smelling. This
was not associated with vaginal bleeding.
4. History cont.
• She had several vaginal examinations and labored for
14 hours at home without progress despite fundal
pressure performed by an untrained TBA and
ingestion of herbal concoctions.
• She presented to PHC where she was augmented for
3 hours and finally referred by an NGO (PUI) to this
hospital.
• There was no history of instrumentation. There was
no associated vaginal bleeding, no fever, no dizziness
or fainting attacks.
5. History of index pregnancy
• Pregnancy was spontaneously conceived desired,
unplanned but suspected by missed period and early
morning nausea and vomiting. The pregnancy was
not confirmed with USS
• Shebooked at PHC and had 2 uneventful visits. She
received 2 doses of TT, IPT and was placed on
heamatinics.
• She perceived first fetal movement at about 5
months of pregnancy. The pregnancy had been
uneventful until the time she went into spontaneous
labour.
6. GYNAE HX
• 14K5/28D0M0
• Not aware of modern family planning, pap
smear or self breast examination and was
adequately counseled
7. PAST MED/ DRUG. Hx
• She is not a known diabetic, hypertensive,
SCDx or asthmatic.
• There is no history of hospitalization
• No previous surgery or blood transfusion, no
known drug allergy.
8. FAMILY AND SOCIAL Hx
• No family hx of diabetes, hypertension or
heart disease.
• No family history of multiple gestation
• Married in a monogamous setting to a small
scale farmer with no formal education
• Not gainfully employed.
• She neither smoke nor ingest alcohol
9. EXAMINATION
General physical Examination
• Young woman, anxious in painful distress,
moderately dehydrated, exhausted, febrile(
axillary temp of 38.9oC), not pale, not
jaundiced, acynosed, no pedal oedema.
• Height: 1.50m, weight : 56kg
10. Abdomen:
• Her abdomen was uniformly enlarged and
moves with respiration, umbilicus is everted,
SFH is 38cm, a singleton fetus lying
longitudinal, presenting cephalic, in ROP,
Descent 2/5th palpable per abdomen, FHR
100b/minutes.
11. Vaginal Examination
• Edematous vulva
• Vagina dry and hot
• Cervix was fully dilated and membranes
absent
• Caput +++, Moulding severe
• Station 0.
15. Management
• She was admitted into labour ward and planed for an
emergency caesarean section.
• The condition was explained to her and she
consented to the operation.
• An IV access was secured with 16G cannula and
blood sample was taken for PCV, grouping and cross
matching, electrolytes, urea and creatinine.
• An indwelling Foleys urethral catheter was inserted
which drained concentrated urine and sample was
taken for urinalysis.
16. Management cont.
• intravenous fluid Normal saline 1L was given fast,
and then continued on 5% Dextrose saline to
alternate with Ringer’s lactate at the rate of 1L 8
hourly.
• Antibiotics were commenced with IV metronidazole
500mg and IV Ceftriaxone 1g stat.
• IM pentazocine 30mg stat was also given for
analgesia.
• IM tetanus toxoid 0.5mls stat and anti tetanus serum
1500 IU was given after a test dose.
• The anaesthetist, neonatologist and theater staff
were informed.
17. INVESTIGATION AND RESULTS
• PCV - 35%
• Blood group - O Rhesus D. Positive
• Bicarbornate - 16mmol/liter (low) normal range 20 –
30mmol/1
• Urea- 6.8mmo1/liter (raised) Normal range 2.5-
5.8mmo1/1
• Other electrolytes and creatinine were within normal
range.
• Urinalysis - Albumin ++
- Glucose negative
• She had two unit of fresh blood cross-matched and kept
in the blood bank.
19. SURGICAL FINDINGS CONT.
• A live male neonate delivered cephalad in
right occipito posterior position, with APGAR
score of 4 and 7 in the 1st and 5th minute
respectively and weight of 2.9kg
• Anterofundal placenta
• Normal ovaries and tubes
• Estimated blood loss was 400mls
20. POSTOPERATIVE PERIOD
• Her immediate postoperative period was satisfactory.
• She was placed on intravenous fluid 5% Dextrose saline to
alternate with Ringer’s lactate 1 L 8 hourly for 24 hours,
intravenous Ceftriaxone 1g 12 hourly & intravenous
metronidazole 500mg 8 hourly for 48 hours and
intramuscular Pentazocine 60 mg 6 hourly for 24 hours.
• Her vital signs were monitored quarter hourly.
• An indwelling Foleys catheter was left insitu for 14 days.
21. POST-OP MANAGEMENT CONT.
• On the second day post operation, her condition and
vital signs were stable.
• The fluid input-output was adequate.
• Bowel sounds had returned and she commenced graded
oral feeds which she tolerated
• Intravenous fluid was discontinued.
• On the 3rd post-operative day, antibiotics were converted
to orals.
• She was continued on tablets Cefuroxime 500mg 12
hourly for 7 days, tablets metronidazole 400mg 8 hourly
for 5 days and Diclofenac potassium 50mg 8 hourly for 5
days.
• She was also placed on haematinics.
22. POST-OP MANAGEMENT
• Her post operation packed cell volume was 30
%.
• On the 7th post-operative day, her vital signs
remained stable, the wound had healed well
and stitches were removed.
• The urethral catheter which was draining clear
urine was removed on the14th post-operative
day and she was discharged home to be seen in
the postnatal clinic after 4 weeks.
23. POST NATAL CLINIC
• She was well and had no complaint. Her general
condition was satisfactory. She was neither pale
nor febrile to touch and her blood pressure was
110/80 mmHg.
• The abdominal examination revealed a
pfannestiel’s scar which healed by primary
intention, abdomen was soft and not tender. The
spleen, liver and kidneys were not palpably
enlarged and uterus was not palpable.
• Vaginal examination revealed a healthy looking
cervix and well-involuted uterus.
24. POST NATAL CLINIC CONT.
• The baby weighed 5.4 kg and was fully
immunized for age. The mother was counseled
on exclusive breast feeding and completion of
her baby’s immunization.
• She was advised to book for antenatal care in
her subsequent pregnancies. She was then
discharged from the clinic and referred to the
Family Planning Clinic.
25. SUMMARY
• Patient is a 19yr old unbooked primigravida at
39weeks of gestation admitted with complaint
of labour pain of 24 hours duration. She was
evaluated and managed as a case of
obstructed labor who had emergency C-
section and was delivered of a live male
neonate who is alive and well and had an
uneventful follow up.
28. DEFINITION
• Obstructed labor is a labor in which progress
has come to a complete halt in the presence of
good and adequate uterine contractions.
Progress here refers to cervical dilatation and
descent of the presenting part.
• This may result either due to factors in the fetus
or in the birth canal or both, so that further
progress is almost impossible without
assistance.
29. EPIDEMIOLOGY
• Worldwide incidence is 2-8% of all
pregnancies accounting for 8% of maternal
mortality
• About 65 million women worldwide have
obstruted labor each year and 2-5% of them
develop VVF and RVF
• In Africa, it varies ranging from 0.4-3.4/100
births in Nigeria
30. EPID. CONT…
• Accounts for 13% of MM in Uganda(according to
international alliance for HIV/AIDS in Uganda)
• In Nigeria;
In Maiduguri, according to a 3-year retrospective
study of all cases of obstructed labor managed at the
department of O&G UMTH between Jan. 1st 2012 to Dec.
31st 2014 ,215 cases of obstructed labor were found out
of 10,109 deliveries giving a prevalence of 2.13%(B. Bako,
E. Barka and A.A Kullima 2014)
31. EPID. CONT…
• It is <2.7% reported in Enugu
>0.8% observed in Kano
35. CLINICAL PRESENTATION
• The patient usually presents with prolonged
labor having severe and continuous pain.
• Abdominal examination reveals the uterus to
be somewhat smaller in size, tense and tender.
• Fetal parts are neither well defined, nor is the
fetal heart sound audible.
• Vaginal examination reveals jammed head with
big caput, dry and edematous vagina.
36. INVESTIGATIONS
• USS
• FBC, EUCr, Urinalysis, Group and cross match 2
units of blood
• Blood culture to rule out sepsis
• Identify the underlying cause
37. TREATMENT
• ACTUAL TREATMENT: The underlying principles are
(1) to relieve the obstruction at the earliest by a safe delivery
procedure,
(2) to correct dehydration and ketoacidosis,and
(3) to control sepsis.
• Preliminaries:
(1) Fluid electrolyte balance and correction of dehydration and
ketoacidosis are done by rapid infusion of Ringer’s solution; at
least 1 liter is to be given in running drip. At least 3 liters of
fluid is required to correct clinical dehydration.
38. TREAT. CONT…
(2) A vaginal swab is taken and sent for culture and sensitivity
test.
(3) Blood sample is sent for group and cross matching and a
bottle of blood should be at hand prior to any operative
intervention.
(4) Antibiotic: ceftriaxone 1 g IV is administered.
(5) IV infusion, metronidazole is given for anaerobic infection..
• Obstetric management: Before proceeding for definitive
operative treatment, uterus rupture must be excluded. There
is no place of “wait and watch”, neither is any scope of using
oxytocin to stimulate uterine contraction.
39. • Vaginal delivery: The baby is invariably dead in most of
the neglected cases and destructive operation is the best
choice to relieve the obstruction. If, however, the head is
low down and vaginal delivery is not risky, forceps
extraction may be done in a living baby.
• Cesarean section: If the case is detected early with good
fetal condition, cesarean section gives the best result.
• Symphysiotomy: can be done in a case of established
obstruction due to outlet contraction with vertex
presentation having good FHS.
42. PREVENTION
• Primary;
Ensuring adequate nutrition especially at puberty
Advocacy, girl child education and public
enlightenment for women to avail themselves for
proper antenatal care and hospital delivery.
Awareness on the effects of early marriage
• Secondary;
Antenatal care
Intrapartum monitoring using partograph
• Tertiary;
Early intervention
43. CONCLUSION
• The prevalence of obstructed labor is high and it remains
as an important cause of feto-maternal morbidity and
mortality. It commonly follows CPD and the risk is higher
for illiterate women, unbooked mother, and teenage
primigravidas while the common complications are
sepsis and uterine rupture.
• Much can be done at the moment, by advocacy, girl
child education and public enlightenment for women to
avail themselves for proper antenatal care and hospital
delivery.
44. BIBLIOGRAPHY
• Babagana Bako, Emmanuel Barka, Abubakar A.
Kullima,Prevalence, risk factors, and outcomes of obstructed
labor at the University of Maiduguri Teaching Hospital,
Maiduguri, Nigeria ;Department of Obstetrics and Gynaecology,
University of Maiduguri Teaching Hospital, Maiduguri, Borno
State, Nigeria 2014
• DC Dutta’s OBSTETRICS including Perinatology and Contraception
8TH ED.
• OBSTRUCTED LABOR; RISK FACTORS & OUTCOME AMONG
WOMEN DELIVERED IN A TERTIARY CARE HOSPITAL ;Dr. Shazia
Rahman Shaikh1, Dr. Khalida Naz Memon2, Dr. Gulzar Usman3