Nuclear physics is a branch of physics that focuses on the study of atomic nuclei and their interactions. It explores the properties and behavior of atomic nuclei, which are the central cores of atoms containing protons and neutrons. This field is crucial for understanding the fundamental forces that govern the behavior of matter at the atomic and subatomic levels.
Norman John Brodeur worked at MIT’s instrumentation lab which later became Draper Labs. My responsibility was instrumentation and guidance systems for the Apollo command module and the lunar module. Previous to that I worked for Avco-Everett Research Lab in Everett. There we focused on testing materials for the vehicle’s heat shield. I was doing heat studies of various materials and what we eventually developed would just burn off and the heat with it.
Introduction to Class 12 Physics - Nuclei:
In the realm of physics, the study of atomic nuclei constitutes a pivotal and intriguing segment, forming the nucleus of Class 12 Physics. Delving into the heart of matter, this section unravels the intricacies of the atomic nucleus, where protons and neutrons converge to define the essence of elements. From the formidable forces that bind these particles to the dynamic processes of radioactive decay, Class 12 Physics - Nuclei unveils the mysteries that govern the core of our physical reality.
As students embark on this journey, they will explore the minuscule dimensions of the nucleus, grapple with the potent forces that operate within, and unravel the applications that extend from nuclear power generation to medical diagnostics. The study of nuclei encapsulates the very essence of matter and energy, offering profound insights into the fundamental nature of the universe.
Through an exploration of nuclear reactions, radioactivity, and the applications that span from energy production to medical advancements, Class 12 Physics - Nuclei equips students with a comprehensive understanding of the microscopic world that shapes the macroscopic reality we inhabit. The journey into the heart of the atom awaits, promising a voyage into the fundamental building blocks that define the physical universe.
For more updates, visit- www.vavaclasses.com
Norman John Brodeur worked at MIT’s instrumentation lab which later became Draper Labs. My responsibility was instrumentation and guidance systems for the Apollo command module and the lunar module. Previous to that I worked for Avco-Everett Research Lab in Everett. There we focused on testing materials for the vehicle’s heat shield. I was doing heat studies of various materials and what we eventually developed would just burn off and the heat with it.
Introduction to Class 12 Physics - Nuclei:
In the realm of physics, the study of atomic nuclei constitutes a pivotal and intriguing segment, forming the nucleus of Class 12 Physics. Delving into the heart of matter, this section unravels the intricacies of the atomic nucleus, where protons and neutrons converge to define the essence of elements. From the formidable forces that bind these particles to the dynamic processes of radioactive decay, Class 12 Physics - Nuclei unveils the mysteries that govern the core of our physical reality.
As students embark on this journey, they will explore the minuscule dimensions of the nucleus, grapple with the potent forces that operate within, and unravel the applications that extend from nuclear power generation to medical diagnostics. The study of nuclei encapsulates the very essence of matter and energy, offering profound insights into the fundamental nature of the universe.
Through an exploration of nuclear reactions, radioactivity, and the applications that span from energy production to medical advancements, Class 12 Physics - Nuclei equips students with a comprehensive understanding of the microscopic world that shapes the macroscopic reality we inhabit. The journey into the heart of the atom awaits, promising a voyage into the fundamental building blocks that define the physical universe.
For more updates, visit- www.vavaclasses.com
PPTs cover the portion of Unit 3 of the subject code ME 6701, Power Plant Engineering.
PPTs cover basics of Nuclear Engineering, Nuclear Fission & nuclear Fusion, Nuclear decay, Half life, Types of reactors
Methods of collection of Nuclear wastes, types of nuclear wastes ans disposal of nuclear wastes.
PPTs cover the portion of Unit 3 of the subject code ME 6701, Power Plant Engineering.
PPTs cover basics of Nuclear Engineering, Nuclear Fission & nuclear Fusion, Nuclear decay, Half life, Types of reactors
Methods of collection of Nuclear wastes, types of nuclear wastes ans disposal of nuclear wastes.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
2. INDEX
1. What is Nuclear Physics?
2. Nucleus
3. Nuclear Force
4. Mass Defect
5. Nuclear Binding Energy
6. Nuclear Reaction
7. Nuclear Fission
8. Nuclear Fusion
9. Radioactivity
10.Radioactive Decay Lay
3. What is Nuclear Physics?
Nuclear physics is the field of physics that studies atomic nuclei and
the constitutions and interactions, in addition to the study of other forms
of nuclear matter.
Nuclear physics should not be confused with atomic physics, which
studies the atom as a whole, including its electrons.
4. Nucleus
The entire positive charge and nearly the
entire mass of atom is concentrated is a
very small space called the nucleus of an
atom.
The nucleus consists of protons and
neutrons. They are called nucleons
5. Nuclear Force
The force acting inside the nucleus or acting between nucleons is called
nuclear force.
Nuclear forces are the strongest forces in nature.
It is a very short range attractive force.
It is non-central and non-conservative force.
It is independent of charge.
It is 100 times that of electrostatic force and 1038 times that of gravitational
force.
According to the Yukawa, the nuclear force acts between the nucleons due to
continuous exchange of meson particles.
6. Mass Defect
The difference between the sum of masses of all nucleons (M) and mass of
the nucleus (m) is called mass defect.
Mass defect (𝚫m) = M - m = [Zmp+ (A - Z)mn - mN]
Mass Energy Relation
Einstein showed that mass is another form of energy and can convert mass
energy into other forms of energy.
Einstein - mass energy, E=mc2
7. Mass Defect
Nuclear Binding Energy
The minimum energy required to separate the nucleons upto an infinite
distance from the nucleus is called nuclear binding energy.
Binding energy, Eb - [Zmp+ (A - Z)mn - mN]c2
Packing Fraction (P)
The larger the value of packing friction, greater is the stability of the
nucleus.
9. Some features of this curve are given below as
1. Nuclei having mass number 50 to 80 are most stable.
2. Nuclei having mass number more than 80, the average binding energy
per nuclei decreases. The nuclei of heavier atoms beyond 83 Bi 209 are
radioactive.
3. Nuclei having mass number below 20 are comparatively less stable.
4. Even-Even nuclei are more stable than their intermediate neighbours.
The nuclei containing even number of protons and even number of neutrons
are most stable. The nuclei containing odd number of protons and odd
number of neutrons are most unstable.
10. Nuclear Reaction
The process by which the identity of a nucleus is changed when it is
bombarded by an energetic particle is called nuclear reaction. Its general
expression is
Q-Value
It means the difference between the rest mass energy of initial
constituents and the rest mass energy of final constituents of a nuclear
reaction.
Parent nucleus Incident particle Compound nucleus product nucleus daughter nucleus energy
X + a → x → Y + b + Q
11. Nuclear Energy
The energy released during nuclear reaction is nuclear energy Two distinct
ways of obtaining energy from nucleus are as
(1) Nuclear fission
(2) Nuclear fusion
Nuclear Fission
The process of the splitting of a heavy nucleus into two or more lighter
nuclei is called nuclear fission.
When a slow moving neutron strikes with a uranium nucleus ( 91U235 ), it
splits into 56Ba141 and 36Kr92 along with three neutrons and a lot of
energy.
91U235 + 0n1 → 56Ba141 + 36Kr92 + 30n1 + energy
12. Nuclear Chain Reaction
If the particle starting the nuclear fission
reaction is produced as a product and
further take part in the nuclear fission
reaction, then chain of fission reaction
started, which is called nuclear chain
reaction.
Nuclear chain reaction are of two types
1. Controlled chain reaction
2. Uncontrolled chain reaction
14. 1. Fuel Fissionable materials like 91U235 , 92U238 , 94Pu239 are used as
fuel.
2. Moderator Heavy water, graphite and beryllium oxide are used to
slower down fast moving neutrons.
3. Coolant The cold water, liquid oxygen etc are used to remove heat
generated in the fission process.
4. Control rods Cadmium or boron rods are good absorber of
neutrons and therefore used to control the fission reaction.
Notes : Atom bomb's working is based on uncontrolled chain reaction.
15. Nuclear Fusion
The process of combining of two lighter nuclei to form one heavy
nucleus is called nuclear fusion.
When three deuteron nuclei (H) are fused, 21.6 MeV is energy released
and nucleus of helium (He) is formed.
1H² + 1H2 + 1H2 → 2He4 + 1H1 + on¹ + 21.6 MeV
In this process, a large amount of energy is released. Nuclear fusion
takes place at very high temperature approximately about 10 K and at
very high pressure 10" atmosphere. Thus, the energy released during
nuclear fusion is known as thermonuclear energy. Hydrogen bomb is
based on nuclear fusion.
The source of sun's energy is the nuclear fusion taking place in the
interior of sun.
16. Radioactivity
The phenomenon of spontaneous emission of radiations by nucleus of
some elements is called radioactivity.
This phenomenon was discovered by Henry Becquerel in 1896.
Radiations Emitted by a Radioactive Element
Three types of radiations emitted by radioactive elements are
1. 𝛼-rays
2. ꞵ-rays
3. 𝛾-rays
17. S.No Property 𝛼 - particle Ꞵ - particle 𝛾 - particle
1 Nature Helium nucleus Fast moving
electrons
Electromagnetic wave
2 Charge +2e -e zero
3 Rest mass 6.67 x 10-27 kg 9.1 x 10-31 kg zero
4 Speed 1.4 x 107 to
2.2 x 107 ms-1
1 to 99 % of c =
3 x 108 ms-1
c = 3 x 108 ms-1
5 Ionising power 104 102 1
6 Penetrating
power
1 102 104
18. ● When an a-particle is emitted by a nucleus its atomic number
decreases by 2 and mass number decreases by 4.
ZXA → Z + 2YA - 4 + 2He4 + ⊽
● When a B-particle is emitted by a nucleus its atomic number is
increases by one and mass number remains unchanged.
ZXA → Z + 1YA + e- + ⊽
● When a y-particle is emitted by a nucleus its atomic number and
mass number remain unchanged.
19. Radioactive Decay Law
The rate of disintegration of radioactive nuclei at any instant is directly
proportional to the number of radioactive nuclei present in the sample at
that instant.
where, λ is the decay constant.
The number of nuclei present undecayed in the sample at any instant
N = N0 e-λt
where, No is number of nuclei at time t=0 and N is number of nuclei at
time t
20. Half-life of a Radioactive Element
The time in which the half number of nuclei present initially in any
sample decays is called half-life (T) of that radioactive element. Relation
between half-life and disintegration constant is given by
21. Average life or mean life (t) of a radioactive element is the ratio of total
life time of all the nuclei and total number of nuclei present initially in the
sample.
Relation between average life and decay constant,
Relation between half-life and average life, τ = 1.44 T1/2
The number of nuclei left undecayed after n half-lives is given by
where, , here t = total time.
Average Life or Mean Life (τ)
22. The activity of a radioactive element is equal to its rate of
disintegration.
Activity, R =
Activity of the sample after time t, R = Re0e-λt
Its SI unit is Becquerel (Bq).
Its other units are Curie and Rutherford.
1 Curie = 3.7x1010 decay's
1 Rutherford = 10° decay/s
Activity of a Radioactive Element