No Needle Mesotheraphy is a revolutionary technique that increases the penetration and spread of active principles into the deep layers of epidermis.

1. NO-NEEDLE
MESOTHERAPY™
Modern alternative to injection mesotherapy

2. 3
NO-NEEDLE MESOTHERAPY™
MAIN FEATURES OF NO-NEEDLE MESOTHERAPY
Unique, non-invasive anti-cellulite and anti-wrinkle treatment
Advanced laser technology
Proprietary electroporation waveforms developed especially
for aesthetic applications
Precisely defined electric pulses for Aquaphoresis process – safe
treatment with no discomfort
Pre-set therapy protocols for all body areas
Easy-to-use and operator friendly
Built-in graphic encyclopaedia for quick reference during treatment
aesthetics@btlnet.com
www.btlaesthetics.com
All rights reserved. Although every care has been taken to provide accurate and up-to-date information, no responsibility can
be accepted for any mistakes or misprints contained in this catalogue. The products and their specifications, as shown in this
catalogue, may change without notice.
NO-NEEDLE MESOTHERAPY
Patient database

3. 5
4
NO-NEEDLE MESOTHERAPY™
AQUAPHORESIS™
The No-Needle Mesotherapy Technology is an advanced, state of the art aesthetic
medicine. It can be used for a variety of facial and body applications.
AquaphoresisTM is a new technique used in aesthetic medicine. It uses combination
of laser or LED technology and proprietary waveforms to start specific physiological
processes in tissue that contribute to rejuvenation of different tissue layers. These
processes include microcirculation, collagen remodeling, lymphatic drainage, and
enhanced blood flow.
MEASURABLE RESULTS IN
Whitening care
Derma-lift care
Anti-wrinkle care
NO-NEEDLE MESOTHERAPY
Anti-cellulite care

4. 7
6
THE AQUAPHORESIS™ PROCESS
IS BASED ON THE SYNERGETIC
EFFECT OF:
THERAPY CHARACTERISTICS
Typical treatment session lasts about 30 minutes
The whole protocol consists of a series of 8–10 sessions
Typical treatment benefits are seen after 4 or 5 visits although results depend
the severity of the condition
After each session the patient may return to normal activity with no downtime
Laser stimulation
Effect of active substances in deep tissue
Muscle tonization & stimulation
Lymphatic stimulation
The No-Needle MesotherapyTM procedure
Aquaporins are a family of specialized proteins in cell membranes
Aquaporins control the inflow and outflow of different molecules includes
water based ones
NNM stimulates cell membrane permeability by precisely defined
electro-stimulation pulses
NO-NEEDLE MESOTHERAPY
CELL WATER CHANNEL
AND AQUAPORINS

5. 9
8
NO-NEEDLE MESOTHERAPY™
ADVANTAGES
Delegated to nurse or technician
Pain free with no swelling or bruising
Standardized drug cocktails
Average treatment time 30 minutes
Body and face treatments
INNOVATIVE APPROACH TO THE
COMPOSITION OF ACTIVE
SUBSTANCE FORMULATIONS
TRANSDERMAL PENETRATION
The depth of penetration achieved with BTL No-Needle MesotherapyTM has been verified
through a University based radioisotope lymphography study. Achieve substances were
mixed with 99 mTc and readily detected in the lymphatic system in less than 20 minutes
and remained visible up to 24 hours. Distribution of the material was extremely even
compared to injection placement. The images were recorded using a Gamma Planar
scanner with collimator, immediately post treatment, 1,2 and 24 hours after treatment. This
is the first scientific study fully documenting non-invasive transdermal penetration.
The research was performed at the prestigious Naval Hospital in Buenos Aires, Argentina,
with the scientific support and direction of Dr. Alberto Croci of the Salvador Nieto
Fundation – an organization dedicated to the study, research and treatment of lymphatic
pathologies. The study had a prospective, longtudinal, and double blind design.
Natural extracts
Complex of amino acids
Transdermal penetration accelerators
Aquaphoresis™ is very patient friendly - the patient will not experience any discomfort
NO-NEEDLE MESOTHERAPY
Aquaphoresis Penetration White Paper available on request

6. 10
RESULTS
Protocol: Abdomen, age: 58 years, cellulite stage: 3 → 2
Before Tx
After 10 Tx
Protocol: Buttock, age: 38 years, cellulite stage: 2 → 1
Before Tx
Age: 46 years, after 7 Tx
After 5 Tx

7. BTL-no-needle-mesotherapy_CAT_EN204
033-77NNMEN204