Nanotechnology in surgery

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Nanotechnology in surgery

  1. 1. Nanotechnology in Surgery<br />Louizos Alexander Louizos<br />ΜSc Nanotechnology & Nanosciences<br />PhD candidate in Nanomechanics<br />Resident in Vascular Surgery<br />
  2. 2. What is NanoTech ?<br />Tech for objects in the size scale of < 100 nm <br />Nanomedicine Nanotechnology in Medicine <br />
  3. 3. “Nature is our playground through a holistic synthetic approach to science”. <br />Biological Material, DNA synthesis <br />MechanicalProperties<br />NOVEL MATERIALS THROUGH NOVEL APPROACH TO SCIENCE<br />Chemistry & SurfaceScience <br />Optical Properties<br />Electronic Properties <br />Electron Microscopy, AFM<br />
  4. 4. Who is the oldest Nanotechnologist? <br />
  5. 5. Mother Nature has had 4.5 billion years to play with inorganic matter and build nanomachines that prove the feasibility of nanotechnology in medicine<br />FACT THAT LED TO BIOMIMETIC TECHNOLOGY<br />
  6. 6. Surgery <br />Surgeons operate in the macro scale. <br />We promote the self healing of the body so we do not heal. The reason for the tissue malfunction is on molecular basis<br />All surgeons (almost all ) know that the more gentle you are with the tissue the less the complications <br />We need lessons from nature on how to heal <br />gently and elegantly from the bottom up!<br />
  7. 7. Trends in surgery<br />We created better tools to assist our hands <br />We begun to be less invasive: Laparoscopic tools , endovascular treatments<br />We created robotic hands that are performing better than human hand: Da Vinci Robotic Surgery<br />We are now experimenting with microrobots ( I will show you some of them) <br />We will finally move to the nanorobotics technology <br />SEEMS BIT FRUSTRATING <br />FOR YOUR TRAINING AS A SURGEON  <br />The only thing that saves us is the time lag between <br />experimental phase, clinical trials and widespread use of methods<br />
  8. 8. Robots in Surgery<br />Da Vinci Robotic Surgery<br />Mag-μbot<br />Endoscopy Capsule<br />Mag-μRobot (Carnegie Mellon )<br />
  9. 9. Nanorobots<br />When and how?<br />In about 10-20 years but we do not know how they will be like. <br />We presume them to be like natural nanomechines (e.g. mitochondria) <br />
  10. 10. Lab On A Chip<br /><ul><li>No need for an angry (why did you awake me up in the middle of the night) microbiologist.
  11. 11. Multiple exams on a small scale machine
  12. 12. Minimal invasive: less blood for the same exams
  13. 13. Can be preventive in nature – Self assessment by patients </li></li></ul><li>Nanoparticle Assisted Surgery<br />Targeted nanoparticles to specific tumors will provide visual guide for the right tissue removal (not too much, not too little). <br />No need for histological tissue exam of the extremities of the oncectomy.<br />
  14. 14. The Ideal Grafts<br />Enhanced Biocompatibility through Biomimetism of nanotopography (still needing surgery for transplantation, hint: Future surgical specialties will be boosted toward transplantation of every possible human part) <br />Artificial Grafts are mistaken for Real Tissue if they look like tissue <br />We should still embed “if they function like tissue” <br />Future of Grafts 3D Printing and Stem Cells<br />The future may be towards “transcendence” meaning hacking of our physiological evolutionary path towards an enhanced man – machine hybrid. (possibly in the next 50 years) <br />
  15. 15. Tissue Engineering - Bioprinting<br />Bioprintingcan be defined as computer-aided, automatic, layer-by-layer deposition, transfer, and patterning of biologically relevant materials.<br />
  16. 16. Potential Dangers of Nanomedicine<br />D.I.Y. Bio: Biotechnology tools on the hands of ordinary people through the miniturization of devices<br />Nanoparticles not yet deeply studied in terms of toxicity and safety<br />Great Goo-> uncontrolled self replicating nanorobots<br />
  17. 17. Love Nano? Help me Spread the word<br />Join me in my blog at http://www.nanotechgalaxy.com , I need help in writing articles. <br />Send me en email at alouisos@gmail.com<br />Join Nanotechnology facebook team at http://on.fb.me/FaceBookNano<br />Follow me on twitter at http://twitter.com/louizos<br />

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