The document outlines a comprehensive approach to emergency neurology assessment, including history taking, differential diagnoses, and management strategies for conditions such as headaches, seizures, and altered mental status. It emphasizes the importance of recognizing red flags in headaches and other neurological symptoms, with guidelines for urgent treatments and imaging when necessary. Additionally, it provides a framework for the evaluation of dizziness, low back pain, and stroke signs, highlighting the critical clinical features and management protocols.

1. DR SHIVAJI MALLAMPATI,
MBBS,FEM,MRCEM.
EMERGENCY PHYSICIAN,
CARE HOSPITALS VIZAG.
NEUROLOGY HISTORY TAKING

2. Differential Diagnosis
VITAMIN CDE
 Vascular
 Inflammatory/Infectious
 Traumatic
 Autoimmune/Allergic
 Metabolic
 Idiopathic/Intoxication/Iatrogenic
 Neoplastic
 Congenital
 Degenerative/Drugs
 Endocrine

3. Histroy Taking
 I PEEP
 I- Introduction( my name is Dr x ,I am the ED
registrar can I confirm your name and age please
 P-Permission ( can I examine your rt knee )
 E- Explanation ( I need to examine in your rt knee
joint to see why you are in pain )
 E-Exposure ( adequately but ensuring dignity is
maintained at all times)
 P-Pain (always check if patient is in pain and offer
analgesia before starting any examination)

4. Presenting complaint
 Pain- SOCRATES
 S-Site ( is it localised or generalised)
 O-Onset (sudden or gradual in onset )
 C-Character(is it sharp ,aching or throbbing in nature)
 R-Radiation (is the pain spreading or localised)
 A-Associations(any associated symptoms)
 T-Timing( related to posture or exercise
 E-Exacerabating or Relieving factors
 S-Severity(how bad it is ? Is it the worst pain ever?)

5.  HOPC
 Past Medical & Surgical Histroy
 Medications & Allergies
 Social Histroy – habits ,occupation,carers
 Gynae & Obstretic histroy in females
 Birth history and immunization status in pediatric

6. Neurology History Taking
 Headache
 Seizures
 Syncope
 Altered Mental Status(AMS)
 Dizziness
 Vertigo
 Low Back ache(LBA)
 FAST
 Visual symptoms

7. Hutchisons Clinical Methods
 In the diagnosis of neurological disease ,it is the
history that is paramount
 Sensory or motor symptoms which are sudden in
onset strongly suggest a vascular origin
Rodney W H
Walkar

8. Headache
 primary headaches :when there is no underlying
cause (such as migraine or cluster headaches)
 secondary headaches : associated with an
underlying cause (such as tumor, meningitis, or
subarachnoid hemorrhage)
 Headache remains as non specific symptom in
the background histroy of fever

9.  Sudden onset of severe headache,thunderclap
headache or “worst headache of their life” is
suggestive of vascular cause
 Subarachnoid hemorrhage or Intracerebral
Hemorrhage
 The imaging modality of choice is CT Brain plain
 Even if the CT is normal and clinical diagnosis is
SAH
 Admit the patient in a moniter bed and do LP to
detect blood or xanthochromia in CSF
 Acute onset of a severe headache is subarachnoid

10. SAH
 The risk of rebleeding is greatest in the first 24 hours
and can be reduced by BP control.
 MAP of <140 mm Hg is a reasonable target while
avoiding hypotension
 DOC :is labetlol ,avoid NTG
 Vasospasm is most common 2 days to 3 weeks after
subarachnoid hemorrhage
 DOC :nimodipine, 60 milligrams PO every 4 hours
,initiated within 96 hours of symptom onset

11.  Headache+ Fever +Altered Mental Status is suggesttive
of
 CNS infection( meningitis ,encephalitis ,Brain abscess)
 Meningismus is an important clinical clue to the
presence of infection or hemorrhage
 95% of patients with bacterial meningitis present
with at least two of the four findings ,classic triad (fever
+neck stiffness+AMS )plus headache).

12.  Never delay administration of empiric antibiotic
therapy for neuroimaging or to perform LP, because
antibiotic treatment takes precedence over definitive
diagnosis.
 ceftriaxone, 2 gm IV plus vancomycin15 mg/kg IV, to
cover the common pathogens S.pneumoniae and N.
meningitides.
 The second priority is administration of steroids to
patients with presumptive pneumococcal meningitis.
 The recommended dosage of dexamethasone is 10
mg IV for adults.
 Consider adding acyclovir if herpes simplex virus

13.  Intracranial hemorrhage may occur with or without a
history of trauma.
 New or progressive headache, with or without
associated neurologic deficit.
 This is particularly important in the elderly, those with
chronic alcohol and substance abuse, and patients
using antiplatelet and anticoagulant agents.
 Acute headache with associated vestibular
symptoms (vertigo or ataxia) should be considered a
cerebellar hemorrhage until proven otherwise.

14.  Headache worsened by Valsalva maneuver.
 Headache causing awakening from sleep.
 Headache that changes with posture.
 Recent cancer diagnosis, or mental status change.

15.  Patients presenting with new headache symptoms,
especially in the presence of certain known risk factors.
 Hypercoagulable states such as use of oral
contraceptives, hematologic disorders, factor V Leiden
homozygous mutation, protein S or protein C deficiency,
and anti–thrombin III deficiency
 Cerebral venous thrombosis ,CVT
 Cerebral venous thrombosis is more common in women,
especially in the peripartum period, and in patients with a
recent surgical history.

16.  Patient presenting with severe headache, visual
changes, seizures, and encephalopathy in the
setting of marked blood pressure elevation.
 It is most common in patients undergoing active
treatment with immunesuppressive or
chemotherapeutic agents, as well as in patients with
end-stage renal disease.
 Posterior Reversible Encephalopathy Syndrome
PRES.

17.  New onset of headache in a elderly male >50 yrs
associated with fever jaw claudication or transient
ischemic attack symptoms, especially transient visual
loss.
 Temporal arteritis, also k/a GCA, is an inflammatory
condition affecting the small and medium-sized intra
and extracranial vessels.
 Diagnosis is made by the presence of three of the five
criteria.
 Begin treatment with prednisone, 60 milligrams PO
daily

18. RCVS
 This condition is one of a short list of conditions that can
mimic subarachnoid hemorrhage.
 Characterized by the occurrence of one or more
“thunderclap” headaches.
 The diagnosis should only be considered when the
evaluation for subarachnoid hemorrhage has proven
negative.
 The key diagnostic feature (multiple areas of cerebral
vasoconstriction on cerebral angiography) is most
commonly found on follow-up angiography between 2
and 3 weeks after symptom onset

19. Hypertensive Headache
 Uncontrolled hypertension can be associated with
headache,especially in conditions where there is a
rapid and marked rise in blood pressure. such as in
 pheochromocytoma,
 posterior reversible encephalopathy syndrome,
 hypertensive crisis,
 pre-eclampsia,
 eclampsia.

21. Red flags of Headache
 Patients should be assessed for clinical features that
suggest a particular cause of headache and ‘red-flag’
features.
 New onset or change in headache in patients who
are age> 50.
 Thunderclap headache.
 Abnormal neurological examination (focal and non-
focal signs).
 Headache that changes with posture.

22.  Change in headache frequency, characteristics, or
associated symptoms.
 Headache precipitated by physical exertion or valsalva
manoeuvre.
 Patients with risk factors for cerebral venous sinus
thrombosis.
 J aw claudication or visual disturbance.
 Neck stiff ness.
 Fever.
 New onset headache in a patient with a history of

23. Syncope VS Seizure
Feature SYNCOPE SEIZURE
Trigger common rare
Prodrome Presyncopal symptoms
like nausea,sweating
,pallor
Aura-unpleasant
smell,epigastric
sensation
Onset Gradual Sudden
Duration 1-30 sec 1-3 min
Colour Usually pale cyanosed
Convulsions May have movement
after LOC
Tonic Clonic
movements,automatism,
neck turned to one side
Tongue Bite Rare ,usually on the tip Common ,on the side
Post Event Rapid recovery ,N/V
afterwards,no post ictial
confusion
Post ictal
Confusion,aching
muscles,joint

25. Altered Mental Status (AMS)
 Consciousness requires two key components of the
central nervous system to be functioning:
 The reticular activating system RAS and at least one
cerebral hemisphere.
 Causes of failure of the reticular activating system
include:
 Brainstem stroke (ischaemic or haemorrhagic).
 Raised intracranial pressure resulting in herniation of
the brain and compression of the brainstem.

26.  Failure of both cerebral hemispheres may occur due to:
 Inadequate blood supply.
 Inadequate substrate for normal metabolism, e.g. oxygen
or glucose.
 Direct or indirect trauma to the cerebrum.
 Exposure of the brain to a toxic insult, e.g. infection, toxic
metabolites, or exogenous poisons.
 A stroke affecting one cerebral hemisphere does not result
in coma because the other hemisphere and the reticular
activating system are still functioning. A brainstem stroke
may lead to coma due to failure of the reticular activating

27. AEIOU TIPS
 Precipitating Causes: AEIOU TIPS
 A – alcohol,acidosis,arrythmias
 E – encephalopathy (hypertensive, hepatic),
electrolytes, endocrine, environmental
 I – insulin (hypoglycemia, HHNK, DKA)
 O – opiates, oxygen (hypoxia)
 U – uremia
 T – trauma, toxins
 I – infection, increased intracranial pressure
 P – psychosis, poisoning (cyanide, carbon
monoxide, etc.), porphyria
 S – stroke, shock , seizure

28. Dizziness VS Vertigo

31. Low Back Ache ( LBA )
 Acute back pain is a very common ED presentation.
 LBA & History of trauma (this may be minimal in the
elderly or those with osteoporosis),Prolonged steroid
use is S/O
 Vertebral Fracture
 LBA with Age <20 or > 50.History of malignancy,Non-
mechanical pain,Thoracic pain,Systemically unwell,
Weight loss,is S/O.

32.  LBA with Fever, Systemically
unwell,IVDU,Immunosuppression,
HIV. Recent bacterial infection,Non-mechanical
pain.Pain worse at night is S/O .
 Spinal Infection.
 LBA withSaddle anaesthesia,Bladder or bowel
dysfunction,Gait disturbance. Widespread or
progressive motor weakness,Bilateral sciatica is S/O .
 Cauda equina syndrome

33.  sudden onset of LBA in elderly male with
hemodynamic compromise& Pulsatile abdominal
mass.
 AAA
 LBA in young age <20with ,Structural deformity of
the spine, Systemically unwell.
 Ankylosing Spondylitis

34. RED FLAGS OF LBA
 Thoracic pain.
 Fever.
 Unexplained weight loss.
 Bladder or bowel dysfunction.
 History of carcinoma.
 Systemically unwell.
 Progressive neurological defi cit.
 Disturbed gait, saddle anaesthesia.
 Age <20 years or > 50 years.

35. CVA
 Sudden numbness or weakness of face, arm, or Leg
especially unilateral
 Sudden altered mental status
 Sudden aphasia
 Sudden memory deficit or spatial orientation or perception
difficulties
 Sudden visual deficit or diplopia
 Sudden dizziness, gait disturbance, or ataxia

37. STROKE MIMICS
 HYPOGLCEMIA
 SEIZURE : TODD” S PALSY
 TIA
 ENCEPHALOPATHY : HONK,
UREMIA,AMMONIA(HE)
 FUNCTIONAL

38. Timing
 To Know whether the patient is in window period .
 Should always be calculated from last seen normal.
 If window period and acute ischaemic stroke with measurable
neurological deficit :
 ED assessment should occur within 10 min.
 CT brain plain should be done within 25 min.
 CT brain to be reported within 45 min.
 IF a candidate for thrombolysis then IV rTpa with in 1 hr.

39. CT brain plain
 Should be normal if acute ischaemic stroke in
window period.