This document discusses adopting a Six Sigma approach to predict functional defects in system testing using predictors from earlier phases. It defines the research focus as using Six Sigma to predict test defects via phases prior to testing. An overview explains that Six Sigma is a data-driven approach to reducing defects in any process. The findings sections explain applying the Six Sigma define, measure, analyze, design, and verify phases to software development. A proposed regression model and verification plan are presented to conclude.