The document summarizes a meeting of the COPDWorkgroup to discuss personalized care for COPD patients. The agenda included introductions, a data and literature review on precision medicine and how it applies to COPD, a discussion of current practices and barriers, and plans for future work. The review presented information on using individual patient traits and lifestyle factors to tailor COPD management, and highlighted pulmonary rehabilitation as a key area that could benefit from a more personalized, patient-centered approach. Barriers to personalized care like psychological factors were also discussed.

1. COPDWorkgroup
Personalized Care for the COPD Patient
January 14th, 2019

2. Agenda
 Introductions
 Data and Literature Review
 Discussion
 Wrap Up

3. Data and
Literature
Review

4. What is
precision
medicine?
 The right treatment, for the right patient, at the right time.
 A form of medicine that uses information about a person’s genes,
proteins, and environment to prevent, diagnose, and treat
disease.
 Tailoring of medical treatment to the specific characteristics of
each patient

5. Data and
Personalized
Medicine
 An increase in biological data and relevant medical information
will be seen with personalized medicine
 We have the ability to analyze these data sets and to extract all of
the useful information

6. COPD and
Personalized
Medicine
 Refers to a label-free, precision medicine approach
 Management is based on individual treatable traits and these
treatable traits are summarized into three groups: pulmonary
treatable traits, extra pulmonary treatable traits, and treatable
behavioral lifestyle risk factors.

7. Personal
Barriers and
Enablers

8. Pulmonary
Rehabilitation:
Personalized
Management
 Pulmonary rehabilitation: an intervention based on a “thorough”
patient assessment followed by therapies designed to improve
physical and psychological conditions
 Healthcare practitioners push for a patient-tailored approach to
improve outcomes.
 Push our patients/physicians to adhere to this long-term

9. The Process of
Getting to a
Patient-
Tailored
Approach

10. Data and
Literature
Conclusion
 Personalized medicine can fundamentally change the ways
therapies are being developed and explore how genetic,
environmental and lifestyle factors interact in our bodies to foster
health or develop disease.

11. Discussion
Overview
 Share current practices
 Analyze trends
 Brainstorm future practices and barriers

12. Discussion
 Is your facility using a patient-tailored approach for COPD
management?
 If so, what does this approach entail?
 What is the biggest psychological/behavioral obstacle your facility
faces related to COPD?
 How does your facility manage these obstacles?
 What self management tools are being used in your facility?
 Do patients have access to their own medical record?

13. NextSteps
 Next COPDWorkgroup:Tuesday, March 3rd from 2-3:30 pm
 Deliverable &Topic:TBD

14. Resources
 Agusti, A. (2014).The path to personalised medicine in
COPD. Thorax, 69(9), 857–864. https://doi.org/10.1136/thoraxjnl-2014-
205507
 Franssen, F. M.,Alter, P., Bar, N., Benedikter, B. J., Iurato, S., Maier, D.,
Maxheim, M., Roessler, F. K., Spruit, M. A.,Vogelmeier, C. F.,Wouters,
E. F., & Schmeck, B. (2019). <p>Personalized medicine for patients
with COPD: where are we?</p>. International Journal of Chronic
Obstructive Pulmonary Disease, Volume 14, 1465–1484.
https://doi.org/10.2147/copd.s175706
 Leung, J. M., Obeidat, M., Sadatsafavi, M., & Sin, D. D. (2019).
Introduction to precision medicine in COPD. European Respiratory
Journal, 53(4), 1802460. https://doi.org/10.1183/13993003.02460-2018
 Wouters, E. (2020). HighWire Lens: Personalised pulmonary
rehabilitation in COPD. Ersjournals.Com.
https://err.ersjournals.com/lens/errev/27/147/170125#toc
 Ziegelstein, R. (2017). Personomics:The Missing Link in the Evolution
from Precision Medicine to Personalized Medicine. Journal of
Personalized Medicine, 7(4), 11. https://doi.org/10.3390/jpm7040011