The musculoskeletal system consists of the muscular system and skeletal system. Together, these systems are responsible for movement and support in the body. The musculoskeletal system is made up of both hard tissues like bones and cartilages, and soft tissues like muscles, tendons, joints, and ligaments. The major organs of the musculoskeletal system are the bones, which make up the skeletal system, including the axial skeleton that protects the central nervous system, and the appendicular skeleton of the arms, legs, shoulders and hips.