The key parameters of a CO2 booster refrigeration system serving a supermarket in Italy were monitored from January to June 2019. The system provided cooling capacities of 20 kW at low temperature and 90 kW at medium temperature evaporators as well as heat recovery for space heating, hot water, and air conditioning. During the winter period, the system operated in transcritical mode to satisfy space heating demands. Monitoring data showed the cooling loads remained constant and will be used to validate models to analyze the performance of different system configurations annually. Simulations predicted up to a 10% reduction in yearly compressor energy use with an optimized overfed evaporator design.