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OVERVIEW OF
HIV AIDS
1
1
2
2
1
3
Overview of HIV – Global Scale of the Problem
3
36.9 million people living with HIV
75 % of people with HIV know their status
HIV testing reached its limit
21.7 million people receiving ART
Key Facts: WHO targets to end HIV pandemic:
New guidelines to increase ART coverage
New set targets for 2020 & 90-90-90 strategy
End AIDS epidemic by 2030
1
4
Overview of HIV – South Africa
4
1
5
90-90-90 Targets
5
1
6
Where Are We NOW?
6
Adoption of the "treat all" recommendation among adults and adolescents living with HIV, October 2016
1
7
HIV Life Cycle : How HIV Infects A Cell
7
1
8
HIV- Prevention, Transmission and Symptoms
8
1
9
HIV Diagnosis
9
Purpose of
the test
For diagnosis
of HIV
infection
Surveillance
of HIV
Infection in
the
population
Screening of
blood and
blood
products
Serological
methods:
antibody/anti
gen-based
test
Enzyme
Immunosorbe
nt Assay
(ELISA)
Western Blot
Viral
detection
methods
PCR
Window
Period
“Period of
time between
the onset of
infection with
HIV and the
appearance of
detectable
antibodies”
Depends on
-Sensitivity of
the test kit
(ability to
detect low
levels of
antibodies)
-Duration of
the body takes
to produces
antibodies (5-7
days) after
infection
-The level of
antibodies
produced (low
levels during
early
infection)
- Elisa
40 different
kits available
High
sensitivity –
99.7%
Rapid Test
Developed in
the late ‘80’s
Be performed
in less than 20
min
Positive result
is indicated by
the appearance
of a dot or line
Examples –
Determine/Un
igold
Confirmatory
tests
All positive
tests should
be confirmed
with another
test
1
10
HIV Testing Services
10
All HIV testing services must follow the 5 Cs principles recommended by WHO:
Informed Consent
Confidentiality
Counselling
Correct Test Results
Connection (linkage to care,
treatment and other services)

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Module 1-OVERVIEW OF HIV AIDS

  • 1. Working towards a healthier you OVERVIEW OF HIV AIDS 1
  • 3. 1 3 Overview of HIV – Global Scale of the Problem 3 36.9 million people living with HIV 75 % of people with HIV know their status HIV testing reached its limit 21.7 million people receiving ART Key Facts: WHO targets to end HIV pandemic: New guidelines to increase ART coverage New set targets for 2020 & 90-90-90 strategy End AIDS epidemic by 2030
  • 4. 1 4 Overview of HIV – South Africa 4
  • 6. 1 6 Where Are We NOW? 6 Adoption of the "treat all" recommendation among adults and adolescents living with HIV, October 2016
  • 7. 1 7 HIV Life Cycle : How HIV Infects A Cell 7
  • 9. 1 9 HIV Diagnosis 9 Purpose of the test For diagnosis of HIV infection Surveillance of HIV Infection in the population Screening of blood and blood products Serological methods: antibody/anti gen-based test Enzyme Immunosorbe nt Assay (ELISA) Western Blot Viral detection methods PCR Window Period “Period of time between the onset of infection with HIV and the appearance of detectable antibodies” Depends on -Sensitivity of the test kit (ability to detect low levels of antibodies) -Duration of the body takes to produces antibodies (5-7 days) after infection -The level of antibodies produced (low levels during early infection) - Elisa 40 different kits available High sensitivity – 99.7% Rapid Test Developed in the late ‘80’s Be performed in less than 20 min Positive result is indicated by the appearance of a dot or line Examples – Determine/Un igold Confirmatory tests All positive tests should be confirmed with another test
  • 10. 1 10 HIV Testing Services 10 All HIV testing services must follow the 5 Cs principles recommended by WHO: Informed Consent Confidentiality Counselling Correct Test Results Connection (linkage to care, treatment and other services)