IOSR Journal of Humanities and Social Science is a double blind peer reviewed International Journal edited by International Organization of Scientific Research (IOSR).The Journal provides a common forum where all aspects of humanities and social sciences are presented. IOSR-JHSS publishes original papers, review papers, conceptual framework, analytical and simulation models, case studies, empirical research, technical notes etc.
The presentation describes various typologies of experiments used to practiced in various fields of social science research. For determination of a sound research design knowledge of types of research design is very important to understand.
EDUC 8102-6 - MD7Assgn5: Research Application Paper #2. eckchela
This is Walden University course (EDUC8102-6) MD7Assgn5: Research Application Paper #2. The purpose of this paper is to compare, contrast, and critique the following articles:
(a) “Conflict Resolution and Transformative Pedagogy a Grounded Theory Research. Project on Learning in Higher Education” by Fetherston and Kelly (2007)
(b) “Gender Differences in Smoking and Meanings of Smoking in Asian-American College Students” by Hsia and Spruijt-Metz (2008). It is written in APA format and includes references. Most universities submit higher-education assignments to turnitin; so, remember to paraphrase. Enjoy your discovery!
The presentation describes various typologies of experiments used to practiced in various fields of social science research. For determination of a sound research design knowledge of types of research design is very important to understand.
EDUC 8102-6 - MD7Assgn5: Research Application Paper #2. eckchela
This is Walden University course (EDUC8102-6) MD7Assgn5: Research Application Paper #2. The purpose of this paper is to compare, contrast, and critique the following articles:
(a) “Conflict Resolution and Transformative Pedagogy a Grounded Theory Research. Project on Learning in Higher Education” by Fetherston and Kelly (2007)
(b) “Gender Differences in Smoking and Meanings of Smoking in Asian-American College Students” by Hsia and Spruijt-Metz (2008). It is written in APA format and includes references. Most universities submit higher-education assignments to turnitin; so, remember to paraphrase. Enjoy your discovery!
Definition
A procedure used to collect both qualitative and quantitative data.
This is done due to the fact that it is believed that both types of studies will provided a clearer understanding of what is being studied.
“It consists of merging ,integrating ,linking ,or embedding the two “strands””(Ceswell,2012).
The Acceptance and Use of Mobile Learning Applications in Higher EducationMark Anthony Camilleri
Many individuals are increasingly using ubiquitous technologies, including interactive applications (apps) that are widely available on our mobile devices, including the smart phones and tablets. Therefore, in the last few years, educators and policy makers have introduced mobile learning (m-learning) technologies in order to support their students during their learning journey. A thorough literature review suggests that there are several contributions in academia that have investigated the students’ acceptance and use of technology, in different contexts. In this light, this research has integrated valid and reliable measures from the Technology Acceptance Model and the Theory of Planned Behavior to better understand the university students’ readiness to engage with mobile technologies for educational purposes. Specifically, this study explores the perceived usefulness and ease of use of m-learning technologies. Moreover, it investigated whether the research participants were influenced by their friends, acquaintances and educators to engage with these technologies and / or by the facilitating conditions at their university. The findings revealed that students held positive attitudes toward the m-learning technologies as they perceived them as useful and easy to use. Moreover, the university’s facilitating conditions had a significant effect on the students’ usage of these technologies. This study also reported that the students’ social influences did not have an effect on their intention to use these devices
An open problem in flow of fluids antonio valiente barderas, lucila méndez ch...eSAT Journals
Abstract
Experimental teaching is very important in education of engineering´ students. This activity promotes the interactivity and the participation of the students, propitiating that they acquire knowledge, skills, habits and attitudes. In this work we present an open problem of flow of fluids that is solved by experimentation, to help the students achieve meaningful learning in this subject.
Keywords: Empirical models, flow of fluids, problem solving, experimentation.
In this paper various approaches, steps and objectives of research are listed and briefly discussed.
This paper discusses four common research approaches, Qualitative, Quantitative, Mixed methods and
Advocacy/participatory research, which were commonly used when conducting research. Research is indeed
civilization and determines the economic, social and political development of a nation. Research is Systematic
investigative process employed to increase or revise current knowledge by discovering new facts. All research
Approaches Examine and explore the different claims to knowledge and are designed to address a specific type
of research question.
Definition
A procedure used to collect both qualitative and quantitative data.
This is done due to the fact that it is believed that both types of studies will provided a clearer understanding of what is being studied.
“It consists of merging ,integrating ,linking ,or embedding the two “strands””(Ceswell,2012).
The Acceptance and Use of Mobile Learning Applications in Higher EducationMark Anthony Camilleri
Many individuals are increasingly using ubiquitous technologies, including interactive applications (apps) that are widely available on our mobile devices, including the smart phones and tablets. Therefore, in the last few years, educators and policy makers have introduced mobile learning (m-learning) technologies in order to support their students during their learning journey. A thorough literature review suggests that there are several contributions in academia that have investigated the students’ acceptance and use of technology, in different contexts. In this light, this research has integrated valid and reliable measures from the Technology Acceptance Model and the Theory of Planned Behavior to better understand the university students’ readiness to engage with mobile technologies for educational purposes. Specifically, this study explores the perceived usefulness and ease of use of m-learning technologies. Moreover, it investigated whether the research participants were influenced by their friends, acquaintances and educators to engage with these technologies and / or by the facilitating conditions at their university. The findings revealed that students held positive attitudes toward the m-learning technologies as they perceived them as useful and easy to use. Moreover, the university’s facilitating conditions had a significant effect on the students’ usage of these technologies. This study also reported that the students’ social influences did not have an effect on their intention to use these devices
An open problem in flow of fluids antonio valiente barderas, lucila méndez ch...eSAT Journals
Abstract
Experimental teaching is very important in education of engineering´ students. This activity promotes the interactivity and the participation of the students, propitiating that they acquire knowledge, skills, habits and attitudes. In this work we present an open problem of flow of fluids that is solved by experimentation, to help the students achieve meaningful learning in this subject.
Keywords: Empirical models, flow of fluids, problem solving, experimentation.
In this paper various approaches, steps and objectives of research are listed and briefly discussed.
This paper discusses four common research approaches, Qualitative, Quantitative, Mixed methods and
Advocacy/participatory research, which were commonly used when conducting research. Research is indeed
civilization and determines the economic, social and political development of a nation. Research is Systematic
investigative process employed to increase or revise current knowledge by discovering new facts. All research
Approaches Examine and explore the different claims to knowledge and are designed to address a specific type
of research question.
CHAPTER 10 MIXED METHODS PROCEDURESHow would you write a mixed mEstelaJeffery653
CHAPTER 10 MIXED METHODS PROCEDURES
How would you write a mixed methods procedure section for your proposal or study? Up until this point, we have considered collected quantitative data and qualitative data. We have not discussed “mixing” or combining the two forms of data in a study. We can start with the assumption that both forms of data provide different types of information (open-ended data in the case of qualitative and closed-ended data in the case of quantitative). If we further assume that each type of data collection has both limitations and strengths, we can consider how the strengths can be combined to develop a stronger understanding of the research problem or questions (and, as well, overcome the limitations of each). In a sense, more insight into a problem is to be gained from mixing or integration of the quantitative and qualitative data. This “mixing” or integrating of data, it can be argued, provides a stronger understanding of the problem or question than either by itself. Mixed methods research, therefore, is simply “mining” the databases more by integrating them. This idea is at the core of a new methodology called “mixed methods research.”
Conveying the nature of mixed methods research and its essential characteristics needs to begin a good mixed methods procedure. Start with the assumption that mixed methods is a methodology in research and that the readers need to be educated as to the basic intent and definition of the design, the reasons for choosing the procedure, and the value it will lend to a study. Then, decide on a mixed methods design to use. There are several from which to choose; consider the different possibilities and decide which one is best for your proposed study. With this choice in hand, discuss the data collection, the data analysis, and the data interpretation, discussion, and validation procedures within the context of the design. Finally, end with a discussion of potential ethical issues that need to be anticipated in the study, and suggest an outline for writing the final study. These are all standard methods procedures, and they are framed in this chapter as they apply to mixed methods research. Table 10.1 shows a checklist of the mixed methods procedures addressed in this chapter.
COMPONENTS OF MIXED METHODS PROCEDURES
Mixed methods research has evolved into a set of procedures that proposal developers and study designers can use in planning a mixed methods study. In 2003, the Handbook of Mixed Methods in the Social and Behavior Sciences (Tashakkori & Teddlie, 2003) was published (and later added to in a second edition, see Tashakkori & Teddlie, 2010), providing a comprehensive overview of this approach. Now several journals emphasize mixed methods research, such as the Journal of Mixed Methods Research, Quality and Quantity, Field Methods, and the International Journal of Multiple Research Approaches. Additional journals actively encourage this form of inquiry (e.g., International Journal of ...
peer1 Qualitative, Quantitative and Mixed MethodThe qualitati.docxbartholomeocoombs
peer1
Qualitative, Quantitative and Mixed Method
The qualitative method of research is characterized by the collection and analysis of textual data like surveys, interviews, focus groups, conversational analysis and observation (Olds, et-al, 2005). The qualitative approach is more uncertain, studying behavior in natural environments using words, images and identify natural patterns and themes. It also generates new hypotheses and theories based on collected data, narrating reports with description, categories and exploration. The qualitative can refute any hypotheses.
Quantitative research methods use statistical analysis for comparing, description and relating variables. It also uses numerical data, hypotheses testing, effect size and interval estimates. This is used to identify statistical relationships and generalized findings. It uses highly structured methods, such as surveys, questionnaires and observation. This can predict casual relationships; quantify variation, study design, statistical assumptions and conditions. This method is inflexible which helps with meaningful comparisons of responses across participants.
The mixed research method on the other hand is deductive and inductive with multiple objectives and forms. It studies behavior in more than one context or condition. Uses numeric variables, words and images with a statistical and holistic approach. In-depth narrative description and identification of overall themes are used as well. One major popular mixed method approach is the sequential explanatory strategy. This has the advantage of having multiple ways to explore a research problem. The mixed method can address problems of different levels, complement the strengths of single design and overcome the weaknesses as well.
The method selected for my final project model would be the qualitative method. This goes into details and more in depth, with cost-effectiveness, flexible times and locations, making interviews easier. It gives a clear picture of complex problems including how and what experiences about the project simply seeking to discover and understand the perspectives and views of people involved.
Citations
Mixed-Methods Approach. (n.d.). http://www.statisticssolutions.com/mixed-methods-approach/
Northeastern university. (n.d.). Retrieved April 21, 2017, from http://www.ccs.neu.edu/
Tan, D. (n.d.). Research design Qualitative, Quantitative, and mixed methods. http://www.scribd.com/doc/51107663/research
peer2
Qualitative Research method is information that is gathered that can be discussed. It gathers information that can be formed into a hypothesis. According to the text, "much like in quantitative research, it is used as a broad explanation for behavior and attitudes, and it may be complete with variables, constructs, and hypotheses" (Creswell, 2013). When testing your hypothesis with qualitative research, there are many different processes that can be .
Qualitative, Quantitative and Mixed MethodThe qualitative method o.docxhildredzr1di
Qualitative, Quantitative and Mixed Method
The qualitative method of research is characterized by the collection and analysis of textual data like surveys, interviews, focus groups, conversational analysis and observation (Olds, et-al, 2005). The qualitative approach is more uncertain, studying behavior in natural environments using words, images and identify natural patterns and themes. It also generates new hypotheses and theories based on collected data, narrating reports with description, categories and exploration. The qualitative can refute any hypotheses.
Quantitative research methods use statistical analysis for comparing, description and relating variables. It also uses numerical data, hypotheses testing, effect size and interval estimates. This is used to identify statistical relationships and generalized findings. It uses highly structured methods, such as surveys, questionnaires and observation. This can predict casual relationships; quantify variation, study design, statistical assumptions and conditions. This method is inflexible which helps with meaningful comparisons of responses across participants.
The mixed research method on the other hand is deductive and inductive with multiple objectives and forms. It studies behavior in more than one context or condition. Uses numeric variables, words and images with a statistical and holistic approach. In-depth narrative description and identification of overall themes are used as well. One major popular mixed method approach is the sequential explanatory strategy. This has the advantage of having multiple ways to explore a research problem. The mixed method can address problems of different levels, complement the strengths of single design and overcome the weaknesses as well.
The method selected for my final project model would be the qualitative method. This goes into details and more in depth, with cost-effectiveness, flexible times and locations, making interviews easier. It gives a clear picture of complex problems including how and what experiences about the project simply seeking to discover and understand the perspectives and views of people involved.
Citations
Mixed-Methods Approach. (n.d.).
http://www.statisticssolutions.com/mixed-methods-approach/
Northeastern university. (n.d.). Retrieved April 21, 2017, from
http://www.ccs.neu.edu/
Tan, D. (n.d.). Research design Qualitative, Quantitative, and mixed methods.
http://www.scribd.com/doc/51107663/research
peer2
Qualitative Research method is information that is gathered that can be discussed. It gathers information that can be formed into a hypothesis. According to the text, "much like in quantitative research, it is used as a broad explanation for behavior and attitudes, and it may be complete with variables, constructs, and hypotheses" (Creswell, 2013). When testing your hypothesis with qualitative research, there are many different processes that can be conducted. .
Doctoral Student
UNIT 1 – Discussion 2
U1D2 – Qualitative Research
JULY 17, 2017
Introduction
According to Leedy & Ormrod (2012), qualitative research incorporates looking at qualities or characteristics that are unlikely to be condensed to numerical values. Ideally, a qualitative research intends to survey multiple complexities and nuances of a specific phenomenon. Therefore, the qualitative research is mostly observed in research that involves complicated human circumstances or complicated human creations. On the other hand, quantitative research aims to establish the quantities or amounts of either one or multiple variables desired. The rationale of the study is to describe qualitative research, its key concepts, and the meaning of scientific merits.
Analysis of Qualitive Research
The qualitative research was majorly used in the Experimental Methods in Political Science. However, the quantitative research was also incorporated in the study. According to McDermott (2002), most political scientists prefer quantitative analysis. The data was gathered in qualitative forms but coded in quantitative analysis appropriate for further related analysis. For example, the behavioral measures required an experiment to establish the behavior of subjects such as videotapes. The videotapes are later examined for characteristics including the facial expressions and dominance in the group. Besides, the physiological measures incorporate data such as blood pressure, galvanic skin responses, and the heart rate.
The Purposive Sampling in Qualitative Research Synthesis just like the title suggests, it is entirely a qualitative form of research. Suri (2011) reveals that an improved number of researches especially from the healthcare and education sector have recognized the benefit of using the qualitative research. Notably, the majority of the growing research appears to be dominated by quantitative research. The study on Ethical Principles and Guidelines for the Protection of Human Subjects of Research has used the quantitative techniques to scrutinize the research protocols (Human Research Protections, 2016). The essence of using the quantitative research is based on the availability to scrutinize the research protocols.
Key Concepts
The key concept investigated in the Experimental Methods in Political Science is the review of the used experiments particularly in political science. Ideally, the first section provides a general synopsis of the experimental measures and designs alongside the threats to external and internal validity (McDermott, 2002). The study has also included the costs and benefits of using the experimentation. The study focuses on the experiments done in diverse fields such as political economy, individual choice literature, and behavioral economics. The study includes several forms of experimentation such as simulation studies, field experiments, and field studies.
The key concept in Purposeful Sampling in Qualitative Re.
There are two types of research in terms of the nature and purpose of the study, namely, (1) basic or fundamental research and (2) applied research.
Basic and applied research are further divided into three types of research in terms of methods, namely, 1) quantitative research, 2) qualitative research, and 3) mixed research method.
An Examination of Effectuation Dimension as Financing Practice of Small and M...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Does Goods and Services Tax (GST) Leads to Indian Economic Development?iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Childhood Factors that influence success in later lifeiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Emotional Intelligence and Work Performance Relationship: A Study on Sales Pe...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Customer’s Acceptance of Internet Banking in Dubaiiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
A Study of Employee Satisfaction relating to Job Security & Working Hours amo...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Consumer Perspectives on Brand Preference: A Choice Based Model Approachiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Student`S Approach towards Social Network Sitesiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Broadcast Management in Nigeria: The systems approach as an imperativeiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
A Study on Retailer’s Perception on Soya Products with Special Reference to T...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
A Study Factors Influence on Organisation Citizenship Behaviour in Corporate ...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Consumers’ Behaviour on Sony Xperia: A Case Study on Bangladeshiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Design of a Balanced Scorecard on Nonprofit Organizations (Study on Yayasan P...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Public Sector Reforms and Outsourcing Services in Nigeria: An Empirical Evalu...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Media Innovations and its Impact on Brand awareness & Considerationiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Customer experience in supermarkets and hypermarkets – A comparative studyiosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Social Media and Small Businesses: A Combinational Strategic Approach under t...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Secretarial Performance and the Gender Question (A Study of Selected Tertiary...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Implementation of Quality Management principles at Zimbabwe Open University (...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Organizational Conflicts Management In Selected Organizaions In Lagos State, ...iosrjce
IOSR Journal of Business and Management (IOSR-JBM) is a double blind peer reviewed International Journal that provides rapid publication (within a month) of articles in all areas of business and managemant and its applications. The journal welcomes publications of high quality papers on theoretical developments and practical applications inbusiness and management. Original research papers, state-of-the-art reviews, and high quality technical notes are invited for publications.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
Nutraceutical market, scope and growth: Herbal drug technologyLokesh Patil
As consumer awareness of health and wellness rises, the nutraceutical market—which includes goods like functional meals, drinks, and dietary supplements that provide health advantages beyond basic nutrition—is growing significantly. As healthcare expenses rise, the population ages, and people want natural and preventative health solutions more and more, this industry is increasing quickly. Further driving market expansion are product formulation innovations and the use of cutting-edge technology for customized nutrition. With its worldwide reach, the nutraceutical industry is expected to keep growing and provide significant chances for research and investment in a number of categories, including vitamins, minerals, probiotics, and herbal supplements.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Mammalian Pineal Body Structure and Also Functions
Mixed Methods Research Approaches:Warrant Consideration Phenomena in theMethodological ThirdMovementon the Humanities Sciences
1. IOSR Journal Of Humanities And Social Science (IOSR-JHSS)
Volume 20, Issue 11, Ver. II (Nov. 2015) PP 21-28
e-ISSN: 2279-0837, p-ISSN: 2279-0845.
www.iosrjournals.org
DOI: 10.9790/0837-201122128 www.iosrjournals.org 21 | Page
Mixed Methods Research Approaches:Warrant Consideration
Phenomena in theMethodological ThirdMovementon the
Humanities Sciences
Kamal koohi
Assistant Professor of Institute ofSocial Research, University of Tabriz
Abstract:Today, Dramatic changes and transformations has happened in theories sociology similar to other
areas.We have seen in recent sociological theories emerging paradigms of integrated. Social research methods
are not exempt from this rule. Simplification of complex social problems cannot be easily by a deterministic
selection approach to both qualitative and quantitative methods. Therefore, since the condition of today's
postmodern discourse of diversity technique, Selection mixed research approach is a methodological necessity
in the social sciences. Today, the simultaneous use of both quantitative and qualitative methods is justified.As
mentioned, the mixed researchapproach qualitative and quantitative methods are combined by each other.The
main objective of this paper is to introduce integrated research approach and review of advantage and
disadvantage mentioned method.
It is expected that using this approach contribute to overcome the shortcomings of positivistic hard and soft
humanistic Blumer. Because the main idea of mixed researchapproach is to combine of qualitative and
quantitative approaches,more appropriate and comprehensive understanding is obtained of topic.
Keywords:Mixed ResearchApproach, Third Movement ofMethodological, Qualitative Method and Quantitative
Method.
I. Introduction
In the present age, significant changes has occurred in sociological theory and paradigm as a
researcher thought and action guidance ( the entire process of research ). So that we are observing the
emergence of mixed theory in recent sociological theories of thinkers such as Bourdieu,Giddens, Habermas ,
Archer and … in order to defect compensation of structural and actors ( micro and macro ) theories. Which
seeks to integrate micro and macro views , the objectivity and subjectivity and in a sense, for elimination false
opposition
Among objectivity, subjectivity and micro and macro . Social research methods are not excluded from
this rule. So that the major approaches in the humanities and social research During the numerous
methodological movements have progressed .The first waveofmethodologybegan with quantitativeand
positivism. After a period ofdomination ofthequantitative research, the deficiency of quantitative research in
people'sthoughts and intentionsofactivities andspecial complex events was revealed people'sthoughts and
intentionsofactivities andspecial events. The second wave of methodology known asqualitative researchin
thedecadeof1970-80began with an emphasis on understanding the processes that led to the results of the study
will be expanded[1]. In the past decade, qualitativemethodology limitationsin generalizing the results,
integration ofresearchfindingswith researcherspecific valuesandproblems ofvalidity and reliability of data were
identified as the major challenges that qualitative research has been faced. therefore, The integrated approach as
a third methodological movement, is critically important. According tothe authors, the basic principle of
integration is a use of differentmethodstoconvergethedifferentperspectives.
In the mentioned method, method based on the positivist and quantitative method according to Blumer
hard method combined with qualitative, interpretation and humanistic Soft methods. According to the
researchers, integrated approach has emerged to solving the problems caused by the use of hard positivistic and
Blumers humanistic soft method in social science. Accordingly, an integrated research approach is an approach
thatresearchers use for data collectionand analysisofqualitative and quantitativemethodsin their research[2]. In
the other words, a mixed theory is a research that qualitative and quantitative methods are combined together in
a single study. This approach has been named as the third methodological movement byTashakkori and Teddlie
in the handbook of mixed theory[3].mixed method consider one or several worldview.Some authors consider
the way of mixed of this research model as a methodology and focus on the philosophical assumptions. And
some authors emphasize the techniques and methods of data collection and analysis .
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Mixedmethods, including philosophical theories and methods of research that leads the collection and
analysis of data and combines quantitative and qualitative approaches many stages of the research process. this
research as a means of collecting, focuses on the analyzing and integrating quantitative and qualitative
information in a separate study or set of studies.the most important assumption is that the use of a combination
of quantitative and qualitative approaches gives better understand of the research subject. If the researcher
choose the integrated approach, it is necessary to realize the research project to predict the mechanisms and
tools to collect information on what research will done. the first mixed approach was called "multi-character,
multi-method". It is also called mixed method approach. In general, the multiplicity of research methods,
proximity and quantitative and qualitative data relevance known as an integrated method[1].advocate of the
combination theory conventionally follow compatibility thesis and the latter philosophy (pragmatic). This theory
is based on the idea that quantitative and qualitative methods compatible with each other and can be combined
them. In pragmatic philosophy, emphasized that researchers have to use integrated approaches that act better in
the real world[4]. according to Johnson and Turner fundamental principle of mixedresearch is that researcher
must use a combination of methods to complete each other's strengths and regulate together
weaknesses[5].Accordingly, being complex and multidimensional of human and social issues does not simplify
with a deterministic selection methods, including quantitative and qualitative methods. So according to
researchers that in today's postmodern stressed to diversity in method, mixed methodology selection is a
methodological necessity in social science. Thereby, Todays the need for both quantitative and qualitative
methods is defensible. when a method, whether qualitative or quantitative research is not enough research to
investigate the matter, preferably we use mixed method. However, since the mixedmethods is desirable that
qualitative data could improve quantitative methods and vice versa, quantitative data could improve qualitative
method [1]. The principal question of this research is, the first what are defects of quantitative and qualitative
method? The second, What are the basic requirements using a mixed methods? The third, What is the most
important types of mixed and what steps including mixed methods?
II. Characteristics of qualitative and quantitative research methods
Empirical methodology that claim the natural science methodology could use in humanities science are
active in scientific research. Positivism that include different branches like logical positivism, naturalism and
behaviorism, have long history among philosophy of science and researchers.In this approach, of natural science
methods used to design humanities research based on quantitative methods. Quantitative methods characterized
by follow Features:
1) Quantitative method emphasize on the relatively small number of concepts(variables)
2) It start of preconceived ideas and discuss about the concepts relations(theories)
3) It uses Formalmethodsand toolsto data collection(like questionnaire)
4) Data collectionwas performed under controlled conditions(control condition).
5) In collecting and analyzing data emphasizes on the problem of objectivity(Moral neutrality).
6) By using statistical methods analyze Numerical data(statistical analyze).
7) The results have a generalized properties.
8) In this study, there is a reproducibility.
9) There is an Individualism in quantitative research
10)Deductive method is used in the research process (theory, hypothesis, data, hypothesis testing, theory).
11)This method consider human behavior as a regular and predictable(behavior Predictability).
12) The main objective is description, explanationand prediction.
13) general purpose of this method is a Quantitative and obtained in response to the question of How often
andHow many.
14) The final report present as a statistical and quantitative report[6,7,8,9,10,11,12].
In contrast, qualitative research a systematic approach to explore and discover the meaning of their life
experiences that are based on different methods.in this regard Donalk notes that qualitative method studied
everyday experiences of life to understand the phenomena that occur naturally and finally give meaning to
everyday life. In this method does not manipulated variable and none of the demographic variables not
controlled[13,14].this type of research with certain definition of human and social realities are trying to study
people social action in a natural context .study of action in relevant social context [15]. And access to the
meaning systems to identify the specific circumstances of each action and according to the prevailing mentality
is a great help. Characteristics of qualitative research are:
1) Natural and social context is a researcher source of information.
2) It is descriptive and The main purpose of it is exploration.
3) Qualitative research is proceeding.
4) Inductive methods used in the analysis.
5) Meaning is a essential component of qualitative research.
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6) Qualitative research is based on subjective.
7) The main technic for data collection is qualitative and various technic (interview, observation, pictures,
notes …) was used.
8) Nature of data is speech, images and categories.
9) Data analysis was to determine the prevailing patterns and the analysis included all aspects of the
matter.
10)The narrative report with a description of the context and direct quotations from participants was
studied.
11) Regarding matter from subjects perspectives.
12) This method has more flexibility.
13) It is not emphasize on Specific concepts (variables) and recognize the phenomenon and its integrity as
a whole.
14) In most cases it has not regular and formal instruments.
15) In the qualitative research, control does not important.
16) It is descriptive and It can be used to generate descriptive and hypothesis, theory development (grounded
theory).
17) general purpose of this method is a Qualitative and obtained in response to the question of what, how and
why[15,10,9,3,4,16,17,18,11,6,7].
III. Similarities and differences of qualitative and quantitative approaches
todays, researchers and social scientists to compare qualitative and quantitative methods and have
recognized the fundamental differences of them in social studies:
1)Epistemological aspect:quantitative research methods is based on Positivist epistemology [8]. Positivists
believe that the main purpose of scientific research is describe and explain of phenomena.in this perspective,
science is a coherent set of statements around specific knowledge that based on empirical tests verifiable or
falsifiable.positivists believe that if human and social sciences being as a scientific status, they must follow the
methods of natural science[19]. The epistemological basis of qualitative research is
interpretivism[4].Interpretivists believe that the main purpose of scientific research is understanding of social
life and discovering how a social meaning creation by people. Interpretativists believe that the prerequisite of
scientific understanding about human and social phenomena, is a common sense and common beliefs to
understand the correct meaning of actors behaviors. And science to be achieved when researchers realized that
accurate definition of the actions[19].
2) Methodological aspect: Quantitative research methods testing the hypothesis by deductive methodology. In
the other words, the logic of theory testing in quantitative method id based on deductive logic.so, in this method,
hypothesis and assumptions deducted of theories and Assess the correctness or incorrectness of the hypotheses
is don based on empirical evidence and natural science. but qualitative research is based on inductive logic. In
this research collected data through inductive logic and in the next stage generated theory and testing the
hypothesis and question. it is believed that accepting a theory in advance not only restricted researchers but also
prevents his attention to the actors view.thus, qualitative researchers are interested in develop concepts and
theories than theory testing. Qualitative methodology suggests that the social world, unlike the physical world
outside and independent of human consciousness does not exist, therefore the social world is not predetermined
that the researchers discovered it[4].
3)Ontological aspect: Quantitative approach follow the type of ontology that social world considered actual and
independent of human mind such as physical world. Patterns and disciplines that there are in the social world
are objective and independent of the perception or interpretation of them. And can be detected with scientific
instrumentsAnd the purpose of identifying is describing and explaining the phenomena that we experience and
knowledge about mete empirical phenomena is not possible.
Qualitative approach based on naturalistic ontology (interpretation), in this approach, there is no pre-defined
external reality.But the reality made through perceptions and interpretations of the participants. In terms of them
there is not a single and isolated reality apart from our perception. and humans have different experiences of the
same phenomena. totally, there are major differences between qualitative and quantitative research
approaches.the main difference between them based on paradigm.
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Table 2: the difference between quantitative and qualitative research approach
Quantitative method Qualitative method
1. positivistic
2. Based on deductive
3.particularistic
4. objective and regard to outside
5. Based on natural science approach
6. trying to control variables
7. The aim is to find the truth and reasons
8. The reality is static
9. Quantitative and numerical data
10. sampling is the random type.
1. phenomenological
2. inductive
3. subjective and focus on internal
4.It is processing
5. It has an anthropological perspective on the world.
6. lack of control
7. The aim is to understand the evaluation of the actors.
8. reality is dynamic
9.Qualitative and textual data
10. sampling is a non-probability type
Adapted from: 20
Despite major differences between two approaches, there is a similarities between quantitative and
qualitative method. The fist, analysis in each of them Accompanied with elicitation. Second, analysis included
general process and researcher regularly collecting data and recorded. Third, comparing of data is a processing
based. The fourth, in both method, researcher try to avoid of errors and wrong conclusion in data collection.
They are also alert to the illusions and false perceptions[7].
Mixed research approach
Mixed research approach is a approach in which researcher in data collection and analysis use
quantitative and qualitative method in a single or several studies in their research[2]. In the other words, a mixed
theory is a research that qualitative and quantitative methods are combined together in a single study. This
approach has been named as the third methodological movement byTashakkori and Teddlie in the handbook of
mixed theory [3].
Green, Crossley and Graham [21] in 57 studies that had been done on the basis of anmixed research
identifying five strategy:
1-Triangulation, 2 -complementarily,3-Development, 4-Initiation 5 -Expansion
1)Triangulation: the study of Integration and verification of the results of many different methods that study
the single phenomenon. And according to denzin a combination of methodologies in single study.triangulation
allows the researcher improve the accuracy of findings based on data from qualitative and quantitative research
methods. for example, triangulation by using qualitative interviews and quantitative questionnaires assessing
the subjects attitudes and perceptions in topic of study[4]. According to Green, Crossley and Graham,
triangulation is the use of different methods(Methods triangulation) different approaches and theories(theoretical
triangulation). So, It can be argued from a variety of triangulation in a single study[10].so we can say that the
main objective of the integration and triangulation is increases the reliability and validity of research results.
2) complementarily: It should be said that words and numbers is a two major factors of human communication
with each other, And usually they are used in all dealing. By combining two methods, it is likely that decrease of
weakness point of a method. in other words, quantitative research in some fields facilitate the qualitative
research and in contrast, the qualitative research and its data can also facilitate quantitative research. the
supplementation of these two methods can be solve a lot of obstacles in the collection and analysis and data
measurement [21].
3) Development: the goal of mixed research is usually to combine the results of a study that provide the
development and formation of a study with other methods' or example, a quantitative survey of the needs and
motivation of subjects can be purposeful sampling determination for interviews about their needs [4,21]. some
believe that the various ideas suited in the evolution of the theory or evolution a range of questions. qualitative
methods are usually appropriate for the exploration and development of hypotheses in beginning of study and
as for the purpose of research questions evolved the need for quantitative research is an important. Finally,
qualitative methods will be appropriate for displaying hypotheses and providing guidance. However, the
evolution of a theory or a problem will be rarely linear and one-dimensional[6].
4) Initiation: for a more extensive analysis of the results of findings used for incompatible quantitative and
qualitative research. in other words, wherever research is questionable or controversial conditions would need to
be sufficient understanding the phenomenon,new study with new insightis generated[4].
5) Expansion: sometimes researchers find that qualitative and quantitative data is heterogeneous and
contradictory, if this inconsistency occurs in the context of a research unit led researcher to a new approach that
can be provide suitable research path. In other words, the inconsistent results can be acts as a platform for
investigating the causes of conflicts and creating new routes[6].
The mixed method steps:
It can be said that there are eight steps in the process of mixed method. it is possible that the process
wont be explained in the order.
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1)Determining the consolidated mixed plan: At this step, design is selected based on the research question. Is it
possible to find an answer to the research question? is it a mixed method would provide the best design to
collect the kind of evidence?
2)the logic of mixed method application: in the second phase determined the purpose of mixed theory. That is
triangulation or completing data? that is Development or Initiation? Does the goal is innovation?[21].
3)Mixed method or plan: is theselected method according to the chronological order, the concurrent or
sequential? At this phase should be selected the priority of method and mixed model projects [12]In other
words, at this stage, the researcher will decide on his design. Of which plan how it can provide the best answer
to the research question?
4) Data collection: At this stage, the data collection is determined. Data collection methods and data analysis
instrument like: questionnaires, interviews, group discussions, observation, etc. is selected.
5) data analysis: in analyzing the data, researchers can use qualitative and quantitative data analysis techniques,
Perhaps the researcher intends to be use quantitative techniques and qualitative techniques concurrently or
separately. in other words, a researcher in the process of quantification, take qualitative data into quantitative
data and in the process of qualitative, take quantitative data into qualitative data [12].
6)Data validation: data validation studied in throughout the mixed method. if the data was invalid, the generated
results will be invalid. For validation of qualitative and quantitative data used the validationstrategies(Empirical
validity, face validity, construct validity, research teams, consensus, integration with other data sources and
integration with initial expectations.
7) Interpretation of data: interpretation of data begins of the first data and continues in all stages of
research.Interpretation and validation of data occurs simultaneously and together. During data interpretation,
can be used different strategies such as reflexivity , negative - case Sampling. In negative - case Sampling
trying to find and examine cases that do not meet the expectations and demands of empirical research.
8)compiling the final report: In the mixed method, report writing can be done during or after the data collection.
researchers should remember that combination present in various stages of research and design and
interpretation is a mixed type. the most important step in this stage is that the researchers combined the results
of qualitative and quantitative data[12].
Mixed method research studies and approaches
Questions are usually planed for mixed method research. In which, The mixed research when, in what
order, at what level, and what proportion, with what means, with what type of analysis performed? And in total,
what is the what is the benefit of mixed research?
1-mixed research usually depend on the types of research questions, data collection, data analysis, interpretation
of results.
2-mixed research may be performed sequentially and simultaneously.
3- The data collection and analyzing may be placed between or within the different levels. Levels may be
include individuals, group, organization and community.
4- Elements of qualitative and quantitative research in mixed method may have equal weight or importance of
one over the other.
5-there is a Techniques and various tools for data collection, such as, questionnaires, structured interviews, open
interviews.
6-In mixed method may be quantitative data take into qualitative data and vice versa [22].
7-one of the main benefits of the mixed methods that it is use the two method and logic process, induction and
deduction. This process caused that findings have a good theoretical and practical basis and generalization,
theorizing occur in favorable condition. there are two major approaches in mixed research approaches: (a)
mixed model (b) mixed method.
(a) mixed model :in this model, a qualitative and quantitative approach are combined to the within of stage or
during stages of research and evaluation processes. Tarynor[12], Johnson[1] have stated two models for mixed
method research: 1-Within – Stage 2-Across- Stage.
Tarynor[12] believed that Within – Stage mixed method research is a approach that qualitative and
quantitative approaches can be combined in one or more stages of the study. for example, researchers in this
approach can be used questionnaires to collecting data. The questionnaire to be included open questions
(qualitative) and closed questions (quantitative). in this case, the model can be considered as within-
stage.According to the Johnson and Anghoboziue[8] in the Across- Stage mixed research combined quantitative
and qualitative approach in two stages. In other words, a types of triangulation may be seen in this type of
research.the following diagram shows the first and the last projects that are done in one method. But the rest of
the project is an mixed project. Because the qualitative and quantitative data collection and analysis of
quantitative and qualitative performed on them.
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Figure 2:The Designs of mixed model
Adapted from:[23,8]
(b) Mixed method:in the plans with mixed method, were combined the stages of qualitative research with
stages of quantitative research in a research process. Designs of mixed method approach classified based on
two major factors: 1-Time order: concurrent, sequential 2-Paradigm: the equal or unequal status and dominant.
in The first factor emphasized that whether the researcher intends to focus on the approach of quantitative and
qualitative data collected and analyzed at the same time or one before the other? In the second criterion is
whether the researchers emphasize that it intends to use the dominant paradigm or the paradigm will change
over time? in this regard, Creswell[2], noted strategies to design an mixed approach for gathering, the priority
and analyzing the data.
1) Sequential explanatory plan: the Strategic goal of this project is to understand the quantitative data
collection and analysis that continues with quantitative analysis and data collection. Priority with
quantitative data. there are two integrated approach during the process of interpretation. this type of
strategy is significant when explaining the role ofqualitative data are responsible for quantitative data.
2) The Sequential exploratory plan: The strategy of this project is to collect data in two stages with the
first priority of all the data that have been collected.in general, the qualitative data tend to collected
previous data and integration of two types of data (quantitative and qualitative) in the analysis. this
strategy is used when the primary purpose of the test is emerging qualitative theories from the data.
3) The Sequential transformative plan: the strategy of this project is to collect data on two separate phases.
It is obvious that the priority of qualitative and quantitative methods depends on theoretical framework.
the project may be more acceptable strategy for researchers that their interests change of
circumstances( like as critical and feminist theory).
4) The concurrent triangulation theory: In this strategy, data collected at a time and aims to improve the
weaknesses of one method with another. Here's priority occurs in the interpretation steps by providing
convergence of findings explanation.
5) The concurrent nested plan: In this strategy, data collected concurrently, but the priority is a study that
guide researcher.this type of strategy can broadly to understanding the phenomenon by which one or
more than one method can be used.
6) The concurrent Transformative plan: In this strategy, data collected concurrently, but the priority with a
theoretical research. similar to the transformative strategy s, these processes directed strongly by the
nature of the research question and theoretical research. Combination any of the methods can lead to
mixed research.
Table 3: Summary of mixed method research
Confirmatory survey
Qualitative data
Statistical analysis
4
Confirmatory survey
Qualitative data
Qualitative analysis
1
Explanatory survey
Quantitative data
Statistical analysis
5
Explanatory survey
Qualitative data
Statistical analysis
2
Confirmatory survey
Quantitative data
Qualitative analysis
6
Explanatory survey
Quantitative data
Qualitative analysis3
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Morgan[24] also referred to the types of mixed method mixed research. an excellent summary of his
pragmatic strategies for combining quantitative and qualitative approach in which quantitative and qualitative
approaches to cover each other's weaknesses are presented in table (4).
Table 4: Models of combining qualitative and quantitative research approaches
Models Qualitative components Quantitative components
Model 1
Qualitative Quantitative
Guide OF quantitative data
collection
Hypothesis
complete the
questionnaire and
survey
Provide basic tools
Principal method
Model 2
Quantitative Qualitative
Principal method
Guide OF qualitative data collection
Provide information of
purposeful sampling
Provide preliminary results to
depths discover
Model 3
Quantitative Qualitative
Quantitative study prosecution:
Evaluation and
interpretation of results
help to researchers
explanation
Principal method
Model 4
Qualitative Quantitative Principal method
Qualitative study prosecution:
Contribute to the generalization
of the results to different
sample
Testing of emerging elements
Adopted from: [24]
Combining of quantitative and qualitative research caused that researcher consider at the phenomenon
from different aspects and more complete understanding of the problem. in general, a combination of qualitative
and quantitative methods can be developed measurement instruments, clarifying concepts, understanding of
causal processes, theory building, testing, and refining and increasing the credibility and reliability of the
findings.
IV. Discussion and conclusion
Mixed research approach as third movement of methodology to overcome the methodological
shortcomings and criticisms to quantitative method as a first methodological movement and qualitative method
as a second methodological movement have been developed in social sciences by experts and experienced
researchers and theorists.quantitative research is said to that it relies too much on statistics and statistical
models. hence, The current processes in everyday social interaction of actors is often overlooked. But, in
qualitative research this processes constitute one of the basic assumptions of research. it is also said that one of
the strengths of quantitative research is the property of the generalizability of the findings. On the contrary, it is
one of the weaknesses of qualitative research methods. Because inthe qualitative method research could not be
generalized the results to the entire community.Therefore ,with regards these cases it can be said that the
research method ends all of these shortcomings and criticism. the basic principle of the mixed method is
combination of different methods and techniques to establish the maximum issue. Mixed research approach is a
approach that researcher used qualitative and quantitative methods in a single or in multiple research studies in
data collection and analysis of them at research program. The mixed research method advocate under the
influence of adaptation theory ends the quantitative and qualitative Paradigm. The mentioned approach based on
the idea that qualitative and quantitative methods are compatible and can be combined them. in this regard, the
Green Cross and Graham stated that the main purpose of mixed method approach is triangle, creating new
boundaries, the complementary data, the potential for expansion and innovation. By comparing the two methods
of qualitative and quantitative research results can be conclude that the strong point of quantitative research is a
weakness point of qualitative research and weakness of quantitative research is the strong point ofqualitative
research. so to avoid falling into the trap of reductionism and ensure greater social studies suggest that
researcher use a combination of research methods. It should be noted that in some studies it is possible that the
use of mixed research approaches is a quantitative or qualitative paradigm. This depends on the nature of the
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research topic. That is the issue is more compatible with one of the paradigms will be the determined paradigm.
It is possible that the quantitative method research to be used in quantitative research method in a stage or
stages Or it may be that quantitative research methods to be used in qualitative research methods in a stage or
stages of it. in the first case the main paradigm will be a quantitative research and in the second case will be a
qualitative research paradigm. the third mode is that paradigms used in mixed research equally. finally, with
recognizing the difficulty of making mixed research main objective of mixed research approach in combining
quantitative and qualitative paradigm is increase understanding of the phenomenon and strengthen their
knowledge and expand the knowledge, provided strong evidence in order to research findings to answerto the
question. So, the mixed method approach as a method, improve the generalizability of results and improve the
understanding of the problem. The final point is that, in social science, the audience of researcher is a subject
and the complexity and multi-dimensional of that need to consider the mixed method. it can be said that the
mixed method research is a double-edged sword that positive function of it, promote understanding of the
problem and study the behavior and dysfunction of it is Time consuming and costly.
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