2. Misoprostol
• Misoprostol is a cytoprotective prostaglandin
PGE1 analogue.
• Reference Reading
• Second Trimester Medical Termination of Pregnancy
with Combined Intracervical and Intravaginal
Misoprostol: Comparative Analysis with Intravaginal
Misoprostol—A Pilot Study
Gaurav Shyam Desai • Abhishek Chandavarkar • Sriram Gopal • Ganpat Sawant •
Shyam V. Desai. The Journal of Obstetrics and Gynecology of India.
3. Diphenhydramine hcl
• Diphenhydramine HCl (Benadryl), a histamine H1 antagonist used as an
antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity
reactions, as a hypnotic, an antiparkinson, and as an ingredient in
common cold preparations.
• Reference Reading
Evaluation of the relationship between cetuximab therapy and
corrected QT interval changes in patients with advanced
malignancies from solid tumors
J. F. Deeken • B. Shimkus • A. Liem • D. Hill • J. Gurtler • E. Berghorn • L. Townes • H.
Lu • O. Trifan • S. Zhang. Cancer Chemother Pharmacol (2013) 71:1473–1483
4. Simvastatin
• Simvastatin is a competitive inhibitor of HMG-
CoA reductase with Ki of 0.1-0.2 nM .
• Reference Reading
• Input of selected human pharmaceutical metabolites into the Norwegian
aquatic environment
• Katherine Langford and Kevin V. Thomas*. J. Environ. Monit., 2011, 13, 416–421
5. Vorinostat
• Vorinostat (suberoylanilide hydroxamic acid,
SAHA) is an HDAC inhibitor with IC50 of ~10
nM.
Reference Reading
Clinical pharmacology profile of vorinostat, a histone deacetylase
inhibitor
Marian Iwamoto • Evan J. Friedman •Punam Sandhu • Nancy G. B. Agrawal. Cancer
Chemother Pharmacol (2013) 72:493–508
6. Atorvastatin
• Atorvastatin Calcium is an inhibitor of HMG-
CoA reductase used as a cholesterol-lowering
medication that blocks the production of
cholesterol.
• Reference Reading
• Oral Nanoparticulate Atorvastatin Calcium is More
Efficient and Safe in Comparison to Lipicure in Treating
Hyperlipidemia
• A. K. Meena, D. Venkat Ratnam, G. Chandraiah. Lipids (2008) 43:231–241
