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PRESCRIPTION PATTERN AND MEDICATION
ADHERENCE IN ASTHMA PATIENTS AT TERTIARY
CARE HOSPITAL.
Under the guidance of:
Mrs MERIN SUSAAN ABRAHAM,
Assistant professor
Department of pharmacy practice
The oxford college of pharmacy, Hongasandra
Bangalore 560068
Under the co-guidance of:
Dr JYOTHI
DEPARTMENT OF PULMONOLOGY
The Oxford Medical College Hospital and research Centre.
Attibele, Bangalore
Name of participants
1. MANOHARA.YM
2. ABHISHEK J
3. AMEEN KHAN
4. ANAND KRISHNA.C
AIMS AND OBJECTIVES
AIM: To study the prescribing pattern and patient medication adherence
in asthma patients.
PRIMARY OBJECTIVE
•To assess the prescribing pattern of drugs in asthma patients.
SECONDARY OBJECTIVE
•To assess the medication adherence of patients.
METHODOLOGY
• STUDY SITE: The Oxford Medical College Hospital and Research Centre,
Attibele
• STUDY DESIGN: PROSPECTIVE CROSS-SECTIONAL STUDY
• STUDY PERIOD: 6 months
• ETHICAL APPROVAL FOR THE STUDY: Ethical approval will be obtained
from the institutional ethics committee of The Oxford Medical College Hospital
and Research Centre, Attibele
SAMPLE SIZE DETERMINATION
The following equation are used for calculating sample size (8)
Desired sample size :
X=
𝑧2𝑃 1−𝑃
ⅇ2
X=(1.96)2(0.131) (0.86)
(0.05)2
X= 0.4327
0.0025
X = 173.11
Required sample size
𝑛 =
𝑁𝑋
X + 𝑁 − 1
n= (150)(173.11)
173.11 + ( 150 -1)
n = 80.64
Z= confidence interval 95% =
1.96
P = Expected prevalence = 0.131
N= Desired sample = 150
Q= (1-p)
n = required sample size
e = error of margin
METHODOLOGY
Cases admitted during the period of 2022
After getting approval from the ethical committee
STEP 1: We obtained consent from 20 patients in both English and Kannada
language
STEP 2: We Collected demographics of the patient (Name, Age, Weight, etc),
prescribed drugs, indication, their route of administration, frequency, dose of drugs,
number of days of stay in case of inpatients through case files and patient interview .
STEP 3:We Obtained data through MARS questionnaires from patient at the time of
visit and follow up through telephone contact.
STEP 4: Assessment and analysis of data collected from MARS questionnaires.
STEP 5: To study the prescribing pattern and medication adherence of drugs in
asthma patient. The obtained data will be subjected to suitable statistical method like
z test .
STUDY CRITERIA
6.6.1 INCULSION CRITERIA:
•Both inpatients and outpatients with asthmatic condition.
•Patients above the age of 12 years.
6.6.2 EXCULSION CRITERIA
• Patient who are not willing to enrol in study.
CONCLUSION
20 cases are collected up to date , the collected cases revealed that the
most commonly prescribed drugs are Nebulizer combimist and
Nebulizer derinide , Nebulizer duolin , which is followed by
montelukast , levocetrizine
After the patient counselling the medication adherence was found to be
improved on follow up conducted
REFERENCE
1. Joseph T . Dipiro. Pharmacotherapy handbook ,9th edition , Mc GRAW hill, ASTHMA edited by terry L schwinghammer , page 821p 2019
2. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease
Study 2019. Lancet. 2020;396(10258):1204-22
3. Subbarao P, Mandhane PJ, Sears MR. Asthma: Epidemiology, etiology and risk factors. Canadian Medical Association Journal. 2009;181(9).
4. Trivedi N. 2020 focused updates to the Asthma Management Guidelines [Internet]. National Heart Lung and Blood Institute. U.S. Department
of Health and Human Services; 2017. Available from: https://www.nhlbi.nih.gov/health-topics/asthma-management-guidelines-2020-updates
5. Srivastava R. assessment of prescription pattern in asthma therapy [Internet]. assessment of prescription pattern in asthma therapy. 2012
Available from:
https://www.researchgate.net/publication/221850111_Assessment_of_Prescription_Pattern_in_Asthma_Therapy_at_Shamli_Hospitals
6. Herfindal Eric T, Helms RA, Quinn DJ. Text book of Therapeutics. 2nd ed. Lippincot William and Wilkins; pp. 658–81.
7. Gourgoulianis K, Hamos B, Christou K, Rizopoulou D, Efthimiou A. Table 3 from prescription of medications by primary care physicians in
the light of asthma guidelines: Semantic scholar [Internet]. undefined. 1998. Available from:
https://www.semanticscholar.org/paper/Prescription-of-Medications-by-Primary-Care-in-the-Gourgoulianis-
Hamos/14cf2f70a1ce13d782bc58e2d827cbbde376d8ea/figure/2
8. Nehra D, Bhalla K, Nanda S, Verma R, Gupta A, Mehra S. Prevalence of bronchial asthma and its associated risk factors in school-going
adolescents in tier-III North Indian city. Journal of Family Medicine and Primary Care. 2018;7(6):1452.
9. Global Asthma Network. The Global Asthma Report. 2018. Available at: http://www.globalasthma
report.org/Global%20Asthma%20Report%202018. pdf. Accessed on 8 September 2019.
10. Kant S. Socioeconomic dynamics of asthma. Indian J Med Res. 2013;138(4):446-8.
11. Bacharier LB, Boner A, Carlsen KH, Eigenmann PA, Frischer T, Gotz M, Helms PJ, Hunt J, Liu A, Papadopoulos N, Platts-Mills T, Pohunek
P, Simons FE, Valovirta E, Wahn U, Wildhaber J: Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy.
2008, 63: 5-34.
12. Carruthers AA, Krska J. Thrombolytics. A drug utilization review in a district general hospital. J Clin Pharm Ther 1997; 22: 335-338.
minimized asthma project is a project related to asthma treatment through GINA GUIDELINES
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minimized asthma project is a project related to asthma treatment through GINA GUIDELINES

  • 1. PRESCRIPTION PATTERN AND MEDICATION ADHERENCE IN ASTHMA PATIENTS AT TERTIARY CARE HOSPITAL. Under the guidance of: Mrs MERIN SUSAAN ABRAHAM, Assistant professor Department of pharmacy practice The oxford college of pharmacy, Hongasandra Bangalore 560068 Under the co-guidance of: Dr JYOTHI DEPARTMENT OF PULMONOLOGY The Oxford Medical College Hospital and research Centre. Attibele, Bangalore Name of participants 1. MANOHARA.YM 2. ABHISHEK J 3. AMEEN KHAN 4. ANAND KRISHNA.C
  • 2. AIMS AND OBJECTIVES AIM: To study the prescribing pattern and patient medication adherence in asthma patients. PRIMARY OBJECTIVE •To assess the prescribing pattern of drugs in asthma patients. SECONDARY OBJECTIVE •To assess the medication adherence of patients.
  • 3. METHODOLOGY • STUDY SITE: The Oxford Medical College Hospital and Research Centre, Attibele • STUDY DESIGN: PROSPECTIVE CROSS-SECTIONAL STUDY • STUDY PERIOD: 6 months • ETHICAL APPROVAL FOR THE STUDY: Ethical approval will be obtained from the institutional ethics committee of The Oxford Medical College Hospital and Research Centre, Attibele
  • 4. SAMPLE SIZE DETERMINATION The following equation are used for calculating sample size (8) Desired sample size : X= 𝑧2𝑃 1−𝑃 ⅇ2 X=(1.96)2(0.131) (0.86) (0.05)2 X= 0.4327 0.0025 X = 173.11 Required sample size 𝑛 = 𝑁𝑋 X + 𝑁 − 1 n= (150)(173.11) 173.11 + ( 150 -1) n = 80.64 Z= confidence interval 95% = 1.96 P = Expected prevalence = 0.131 N= Desired sample = 150 Q= (1-p) n = required sample size e = error of margin
  • 5. METHODOLOGY Cases admitted during the period of 2022 After getting approval from the ethical committee STEP 1: We obtained consent from 20 patients in both English and Kannada language STEP 2: We Collected demographics of the patient (Name, Age, Weight, etc), prescribed drugs, indication, their route of administration, frequency, dose of drugs, number of days of stay in case of inpatients through case files and patient interview . STEP 3:We Obtained data through MARS questionnaires from patient at the time of visit and follow up through telephone contact. STEP 4: Assessment and analysis of data collected from MARS questionnaires. STEP 5: To study the prescribing pattern and medication adherence of drugs in asthma patient. The obtained data will be subjected to suitable statistical method like z test .
  • 6. STUDY CRITERIA 6.6.1 INCULSION CRITERIA: •Both inpatients and outpatients with asthmatic condition. •Patients above the age of 12 years. 6.6.2 EXCULSION CRITERIA • Patient who are not willing to enrol in study.
  • 7. CONCLUSION 20 cases are collected up to date , the collected cases revealed that the most commonly prescribed drugs are Nebulizer combimist and Nebulizer derinide , Nebulizer duolin , which is followed by montelukast , levocetrizine After the patient counselling the medication adherence was found to be improved on follow up conducted
  • 8. REFERENCE 1. Joseph T . Dipiro. Pharmacotherapy handbook ,9th edition , Mc GRAW hill, ASTHMA edited by terry L schwinghammer , page 821p 2019 2. Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020;396(10258):1204-22 3. Subbarao P, Mandhane PJ, Sears MR. Asthma: Epidemiology, etiology and risk factors. Canadian Medical Association Journal. 2009;181(9). 4. Trivedi N. 2020 focused updates to the Asthma Management Guidelines [Internet]. National Heart Lung and Blood Institute. U.S. Department of Health and Human Services; 2017. Available from: https://www.nhlbi.nih.gov/health-topics/asthma-management-guidelines-2020-updates 5. Srivastava R. assessment of prescription pattern in asthma therapy [Internet]. assessment of prescription pattern in asthma therapy. 2012 Available from: https://www.researchgate.net/publication/221850111_Assessment_of_Prescription_Pattern_in_Asthma_Therapy_at_Shamli_Hospitals 6. Herfindal Eric T, Helms RA, Quinn DJ. Text book of Therapeutics. 2nd ed. Lippincot William and Wilkins; pp. 658–81. 7. Gourgoulianis K, Hamos B, Christou K, Rizopoulou D, Efthimiou A. Table 3 from prescription of medications by primary care physicians in the light of asthma guidelines: Semantic scholar [Internet]. undefined. 1998. Available from: https://www.semanticscholar.org/paper/Prescription-of-Medications-by-Primary-Care-in-the-Gourgoulianis- Hamos/14cf2f70a1ce13d782bc58e2d827cbbde376d8ea/figure/2 8. Nehra D, Bhalla K, Nanda S, Verma R, Gupta A, Mehra S. Prevalence of bronchial asthma and its associated risk factors in school-going adolescents in tier-III North Indian city. Journal of Family Medicine and Primary Care. 2018;7(6):1452. 9. Global Asthma Network. The Global Asthma Report. 2018. Available at: http://www.globalasthma report.org/Global%20Asthma%20Report%202018. pdf. Accessed on 8 September 2019. 10. Kant S. Socioeconomic dynamics of asthma. Indian J Med Res. 2013;138(4):446-8. 11. Bacharier LB, Boner A, Carlsen KH, Eigenmann PA, Frischer T, Gotz M, Helms PJ, Hunt J, Liu A, Papadopoulos N, Platts-Mills T, Pohunek P, Simons FE, Valovirta E, Wahn U, Wildhaber J: Diagnosis and treatment of asthma in childhood: a PRACTALL consensus report. Allergy. 2008, 63: 5-34. 12. Carruthers AA, Krska J. Thrombolytics. A drug utilization review in a district general hospital. J Clin Pharm Ther 1997; 22: 335-338.