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CASE PRESENTATION ON MI
Roll no:17Q0705
SUBJECTIVE EVIDENCE
Patient Details:
 Name – XYZ
 Age-65
 Sex - Male
 Weight – 56 Kg
 IP No.-186349
 D.O.A – 1/8/20
• Reason for admission:
C/o Chest pain radiating
towards left shoulder, left arm*3 hrs before
admission, sweating during attack.
• Past medical history:
K/C/O Hypertension * 1 year
on Rx non adherent
• Past medication history: --
• Social history :
Chronic smoker * 12 years
(10beedies/day)
OBJECTIVE EVIDENCE
1]LABORATORY INVESTIGATIONS
DATE 1/8 2/8 3/8 4/8 5/8 6/8
BP 160/10
0
150/90 140/90 140/86 130/86 130/80
PULSE
RATE
90 88 86 88 82 82
2]BLOOD COUNT:
PATIENT VALUE
Haemoglobin 11.2g/dL
WBC 8200 cells/mm³
Neutrophils 67%
Leukocyte 28%
Monophils 2%
Eosinophils 3%
Basophils 0%
Platelets 3.30 lakh cells/mm³
ESR 20 mm/Hr
3]CARDIAC ENZYMES:
CKMB 146 IU/L
AST 124 U/L
LDH 1149 U/L
LIPID PROFILE TEST
TC : 179 mg/dL
HDL : 56 mg/dL
TG : 114 mg/dL
LDL : 125mg/dL
VLDL : 15mg/dL
RENAL FUNCTION TEST
• Urea : 28 mg/dL
• Serum Creatinine : 1.2 mg/dL
ELECTROLYTES
• Sodium : 120 m moles/L
• Potassium : 3.7 m moles/L
• Chloride : 98 m moles/L
OTHER INVESTIGATIONS
• ECG : ST wave elevation and T wave inversion
in V1 – V4
ASSESSMENT
Subjective evidence : C/o chestpain radiating to
left arm, associated with sweating
Objective evidence : elevated CKMB, AST,LDH
ECG shows ST elevation and T wave inversion
From subjective and objective evidence the patient
is diagnosed with MYOCARDIAL INFARCTION
GOALS OF TREATMENT
• To releive signs and symptoms
• Tp reperfuse the infarcted area as early as
possible
• To prevent further reocclusion and
reinfarction
• To prevent further complications
• To provide better patient care
TREATMENT CHART
O GENERIC NAME ROUTE DOSE FREQ 1 2 3 4 5
O2 inhalation 3L/min Y Y Y Y Y
Inj.Morphine Iv 4mg stat Y Y Y Y Y
Inj. Promethazine IV 12.5 mg stat Y Y Y Y Y
Inj.Streptokinase IV 1.5 MIU stat Y Y Y Y Y
T.Clopidogrel + Aspirin PO 75/150 mg 0-1-0 Y Y Y Y Y
Inj.NTG IV
infusion
2.5mcg/min Y Y Y Y Y
T.Atorvaststin PO 10mg 1-0-0 Y Y Y Y Y
T.Ramipril PO 5mg 1-0-0 Y Y Y Y Y
Inj.Dalteparin SC 5000 U 1-0-1 N Y Y Y Y
GOALS ACHIEVED
• Signs and Symptoms were releived
• Attempt was made to prevent complications.
DRUG INTERACTIONS
• Dalteparin + Clopidogrel
Either increases effects of other by
pharmacodynamic synergism.
• Aspirin + Ramipril
Results in a Significant decrease in renal
function
• Dalteparin + Ramipril
Dalteparin increases toxicity of ramipril
PHARMACIST INTERVENTION
• Troponin I levels were not estimsted
• PT,INR were not measured
• Sub therepeutic dose – Inj.Dalteparin
• Unindicated use of Promethazine
PATIENT COUNSELLING
• Take medications properly and regularly
• Smoking cessation
• Eating food with a high content of saturated or trans fatty
acids should be minimised, replaced by unsaturated fats
such as olive oil,avacados and nuts
• A balanced diet which is high in vegetables and legumes
to be taken
• Salt restriction in diet
• Exercise regulary
• Manage stress appropriately
MI is cardiovascular disorder with infarction in cardiac muscles which leads to less oxygen supply

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MI is cardiovascular disorder with infarction in cardiac muscles which leads to less oxygen supply

  • 1. CASE PRESENTATION ON MI Roll no:17Q0705
  • 2. SUBJECTIVE EVIDENCE Patient Details:  Name – XYZ  Age-65  Sex - Male  Weight – 56 Kg  IP No.-186349  D.O.A – 1/8/20
  • 3. • Reason for admission: C/o Chest pain radiating towards left shoulder, left arm*3 hrs before admission, sweating during attack. • Past medical history: K/C/O Hypertension * 1 year on Rx non adherent • Past medication history: -- • Social history : Chronic smoker * 12 years (10beedies/day)
  • 4. OBJECTIVE EVIDENCE 1]LABORATORY INVESTIGATIONS DATE 1/8 2/8 3/8 4/8 5/8 6/8 BP 160/10 0 150/90 140/90 140/86 130/86 130/80 PULSE RATE 90 88 86 88 82 82
  • 5. 2]BLOOD COUNT: PATIENT VALUE Haemoglobin 11.2g/dL WBC 8200 cells/mm³ Neutrophils 67% Leukocyte 28% Monophils 2% Eosinophils 3% Basophils 0% Platelets 3.30 lakh cells/mm³ ESR 20 mm/Hr
  • 6. 3]CARDIAC ENZYMES: CKMB 146 IU/L AST 124 U/L LDH 1149 U/L
  • 7. LIPID PROFILE TEST TC : 179 mg/dL HDL : 56 mg/dL TG : 114 mg/dL LDL : 125mg/dL VLDL : 15mg/dL
  • 8. RENAL FUNCTION TEST • Urea : 28 mg/dL • Serum Creatinine : 1.2 mg/dL
  • 9. ELECTROLYTES • Sodium : 120 m moles/L • Potassium : 3.7 m moles/L • Chloride : 98 m moles/L
  • 10. OTHER INVESTIGATIONS • ECG : ST wave elevation and T wave inversion in V1 – V4
  • 11. ASSESSMENT Subjective evidence : C/o chestpain radiating to left arm, associated with sweating Objective evidence : elevated CKMB, AST,LDH ECG shows ST elevation and T wave inversion From subjective and objective evidence the patient is diagnosed with MYOCARDIAL INFARCTION
  • 12. GOALS OF TREATMENT • To releive signs and symptoms • Tp reperfuse the infarcted area as early as possible • To prevent further reocclusion and reinfarction • To prevent further complications • To provide better patient care
  • 13. TREATMENT CHART O GENERIC NAME ROUTE DOSE FREQ 1 2 3 4 5 O2 inhalation 3L/min Y Y Y Y Y Inj.Morphine Iv 4mg stat Y Y Y Y Y Inj. Promethazine IV 12.5 mg stat Y Y Y Y Y Inj.Streptokinase IV 1.5 MIU stat Y Y Y Y Y T.Clopidogrel + Aspirin PO 75/150 mg 0-1-0 Y Y Y Y Y Inj.NTG IV infusion 2.5mcg/min Y Y Y Y Y T.Atorvaststin PO 10mg 1-0-0 Y Y Y Y Y T.Ramipril PO 5mg 1-0-0 Y Y Y Y Y Inj.Dalteparin SC 5000 U 1-0-1 N Y Y Y Y
  • 14. GOALS ACHIEVED • Signs and Symptoms were releived • Attempt was made to prevent complications.
  • 15. DRUG INTERACTIONS • Dalteparin + Clopidogrel Either increases effects of other by pharmacodynamic synergism. • Aspirin + Ramipril Results in a Significant decrease in renal function • Dalteparin + Ramipril Dalteparin increases toxicity of ramipril
  • 16. PHARMACIST INTERVENTION • Troponin I levels were not estimsted • PT,INR were not measured • Sub therepeutic dose – Inj.Dalteparin • Unindicated use of Promethazine
  • 17. PATIENT COUNSELLING • Take medications properly and regularly • Smoking cessation • Eating food with a high content of saturated or trans fatty acids should be minimised, replaced by unsaturated fats such as olive oil,avacados and nuts • A balanced diet which is high in vegetables and legumes to be taken • Salt restriction in diet • Exercise regulary • Manage stress appropriately