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MICROBIALSTRESS
RESPONSE
PRAGYA TYAGI
MICROBIOLOGY
 Just like human beings, microbes have to deal with continuous stress. However, stress
 for microbes is different from the stress humans are used to-it causes damage to
 macromolecules, membranes, proteins and nucleic acids.
 It can be chemical stress, caused by toxic and harmful compounds, or physical stress.
 For example heat.
• A limited supply of nutrients can also be regarded as stress. Microbes have developed stress responses,
to temporarily increase tolerance limits.
• Some stress responses facilitate bacterial transition from a free living organism to a host-invading
pathogen.
• When supplied with sufficient nutrients and optimal growth temperature, pH ,Oxygen levels and solute
concentrations, will grow at a maximum growth rate characteristics for the organisms.
• Variations in these parameters can affect the maximum growth rate and thus, can represent an
environmental stress for the microbe.
• As a result, bacteria live in a constant state of stress.
• Cells respond to hypoosmotic environment by sudden rapid cell swelling, but within
minutes, they start to return to their original volume
• Osmotic stress-----
• Bacteria experience osmotic stress when the osmotic pressure of their
environment is variable, extremely low, or extremely high.
• Osmotic stress tolerance mechanisms determine whether bacteria survive or
grow because osmotic stress profoundly affects the structure, physics, and
chemistry of bacterial cells.
• Water flows out of cell as their medium become more concentrated and into
cells as their medium becomes more dilute.
• Bacteria attenuates such water fluxes by accumulating and releasing electrolytes
and small organic solutes.
Basically Osmotic stress is a sudden change in the solute
concentration around a cell, causing change in the movement of
water across its cell Membrane.
OSMOTIC STRESS
HYPEROSMOTIC HYPOOSMOTIC
THANKYOU

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Microbial stress response

  • 2.  Just like human beings, microbes have to deal with continuous stress. However, stress  for microbes is different from the stress humans are used to-it causes damage to  macromolecules, membranes, proteins and nucleic acids.  It can be chemical stress, caused by toxic and harmful compounds, or physical stress.  For example heat.
  • 3. • A limited supply of nutrients can also be regarded as stress. Microbes have developed stress responses, to temporarily increase tolerance limits. • Some stress responses facilitate bacterial transition from a free living organism to a host-invading pathogen. • When supplied with sufficient nutrients and optimal growth temperature, pH ,Oxygen levels and solute concentrations, will grow at a maximum growth rate characteristics for the organisms. • Variations in these parameters can affect the maximum growth rate and thus, can represent an environmental stress for the microbe. • As a result, bacteria live in a constant state of stress.
  • 4. • Cells respond to hypoosmotic environment by sudden rapid cell swelling, but within minutes, they start to return to their original volume
  • 5. • Osmotic stress----- • Bacteria experience osmotic stress when the osmotic pressure of their environment is variable, extremely low, or extremely high. • Osmotic stress tolerance mechanisms determine whether bacteria survive or grow because osmotic stress profoundly affects the structure, physics, and chemistry of bacterial cells. • Water flows out of cell as their medium become more concentrated and into cells as their medium becomes more dilute. • Bacteria attenuates such water fluxes by accumulating and releasing electrolytes and small organic solutes.
  • 6. Basically Osmotic stress is a sudden change in the solute concentration around a cell, causing change in the movement of water across its cell Membrane. OSMOTIC STRESS HYPEROSMOTIC HYPOOSMOTIC