This document discusses different types of microorganisms. It identifies six main types: fungi, algae, bacteria, archaea, viruses, and protozoa. Fungi grow on decaying matter and spread spores. Algae are essential as they produce oxygen and were the first living species to evolve respiration. Bacteria can cause disease or be useful, and come in different shapes. Archaea are prokaryotes without cell nuclei. Viruses act as non-living outside cells but living inside when they infect cells. Protozoa are single-celled eukaryotes that feed on organic matter or tissues.
Eubacteria are the most commonly found organisms in the world. They are also known as true bacteria, and are present on almost all surfaces. They are prokaryotic cells, and hence do not have a nucleus. The eubacteria kingdom is one of the six kingdoms in which the entire living world is classified.
BASIC CONCEPTS OF VIRUS AND ITS LIFE CYCLE. Introduction of viriods and prions are also given. various types of viruses with structures are given. both lytic and lysogenic cycle of virus is given. At the end how prions causes misfolding of proteins in brain is given.
Eubacteria are the most commonly found organisms in the world. They are also known as true bacteria, and are present on almost all surfaces. They are prokaryotic cells, and hence do not have a nucleus. The eubacteria kingdom is one of the six kingdoms in which the entire living world is classified.
BASIC CONCEPTS OF VIRUS AND ITS LIFE CYCLE. Introduction of viriods and prions are also given. various types of viruses with structures are given. both lytic and lysogenic cycle of virus is given. At the end how prions causes misfolding of proteins in brain is given.
Intro of Micro-organisms, Bacteria, Use of bacteria, Harmful bacteria,Reproduction in bacteria, virus,
Reproduction in virus, Fungi, Use of fungi, Harmful fungi,
Reproduction in fungi
Module 7 OverviewOrigin and Classification of LifeThe origin o.docxmoirarandell
Module 7 Overview
Origin and Classification of Life
The origin of life has been of great debate for centuries. This module will outline the various ideas of how life and Earth itself developed. You will learn the evidence for multiple theories on the origin of life and the evolution of these theories based on new scientific findings.
This module will also focus upon one of the most important achievements of the science of biology: the classification of organisms and the creation of an internationally agreed upon system of nomenclature. Understanding how organisms are classified provides an important basis for any future studies in ecology.
Learning Objectives
Upon completion of this module, you should be able to:
10A
Describe the evidence used to suggest an extraterrestrial source for life on earth.
10B
State the most probable physical conditions on early Earth and the changes thought to have happened before life could exist.
10C
Differentiate between the concepts of spontaneous generation and biogenesis.
10D
Examine the chemical and physical events that must have occurred to have life originate on Earth.
10E
Describe the different hypotheses for what the first living thing might have been like.
10F
Identify the way in which organisms have caused the atmosphere of the earth to change.
10G
State the order and approximate times for major evolutionary events.
10H
Examine the endosymbiotic theory.
10I
Explain the experimental evidence for the origin of life from organic and inorganic material.
10J
Distinguish between taxonomy and phylogeny.
10K
Describe the kinds of tools used to establish phylogenetic relationships.
10L
Distinguish among viruses, viroids, and prions.
10M
Describe the scientific method for naming organisms.
11A
List and give distinguishing characteristics of the kingdoms within the Domain Eukarya.
11B
Distinguish between Bacteria and Archaea.
11C
Explain the features that differentiate organisms as microbes.
11D
List the basic characteristics of members of the Protista, Archaea, Bacteria, and Fungi.
11E
Identify the type of environments in which microorganisms live.
Module 7 Reading Assignment
Enger, E. D., Ross, F. C., & Bailey, D. B. (2012). Concepts in biology (14th ed.). New York: McGraw-Hill. Chapters 19, 20, and 21.
Optional Reading Assignment:
Chapter 22, The Plant Kingdom, and Chapter 23, The Animal Kingdom.
Origin and Classification of Life
Scientists have broken down life into domains of organisms. Scientists believe that at first life, there was first the bacteria domain. The bacteria domain was followed by the archaea domain and finally, the eucarya domain. Domain bacteria and domain archaea remain the same and have not been further broken down. Domain eucarya was further broken down into the plant kingdom, the fungi kingdom, and the animal kingdom.
Organisms live on, in, and within all types of environments. Organisms can be found from pole to pole and everywhere in between. This includ ...
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micro, microorganism, friend , foe, science , activity, 8th class
types of microorganism
types of bacteria
fungus protozoa
algae
viruses
diseases
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
THE IMPORTANCE OF MARTIAN ATMOSPHERE SAMPLE RETURN.Sérgio Sacani
The return of a sample of near-surface atmosphere from Mars would facilitate answers to several first-order science questions surrounding the formation and evolution of the planet. One of the important aspects of terrestrial planet formation in general is the role that primary atmospheres played in influencing the chemistry and structure of the planets and their antecedents. Studies of the martian atmosphere can be used to investigate the role of a primary atmosphere in its history. Atmosphere samples would also inform our understanding of the near-surface chemistry of the planet, and ultimately the prospects for life. High-precision isotopic analyses of constituent gases are needed to address these questions, requiring that the analyses are made on returned samples rather than in situ.
(May 29th, 2024) Advancements in Intravital Microscopy- Insights for Preclini...Scintica Instrumentation
Intravital microscopy (IVM) is a powerful tool utilized to study cellular behavior over time and space in vivo. Much of our understanding of cell biology has been accomplished using various in vitro and ex vivo methods; however, these studies do not necessarily reflect the natural dynamics of biological processes. Unlike traditional cell culture or fixed tissue imaging, IVM allows for the ultra-fast high-resolution imaging of cellular processes over time and space and were studied in its natural environment. Real-time visualization of biological processes in the context of an intact organism helps maintain physiological relevance and provide insights into the progression of disease, response to treatments or developmental processes.
In this webinar we give an overview of advanced applications of the IVM system in preclinical research. IVIM technology is a provider of all-in-one intravital microscopy systems and solutions optimized for in vivo imaging of live animal models at sub-micron resolution. The system’s unique features and user-friendly software enables researchers to probe fast dynamic biological processes such as immune cell tracking, cell-cell interaction as well as vascularization and tumor metastasis with exceptional detail. This webinar will also give an overview of IVM being utilized in drug development, offering a view into the intricate interaction between drugs/nanoparticles and tissues in vivo and allows for the evaluation of therapeutic intervention in a variety of tissues and organs. This interdisciplinary collaboration continues to drive the advancements of novel therapeutic strategies.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
A brief information about the SCOP protein database used in bioinformatics.
The Structural Classification of Proteins (SCOP) database is a comprehensive and authoritative resource for the structural and evolutionary relationships of proteins. It provides a detailed and curated classification of protein structures, grouping them into families, superfamilies, and folds based on their structural and sequence similarities.
Introduction:
RNA interference (RNAi) or Post-Transcriptional Gene Silencing (PTGS) is an important biological process for modulating eukaryotic gene expression.
It is highly conserved process of posttranscriptional gene silencing by which double stranded RNA (dsRNA) causes sequence-specific degradation of mRNA sequences.
dsRNA-induced gene silencing (RNAi) is reported in a wide range of eukaryotes ranging from worms, insects, mammals and plants.
This process mediates resistance to both endogenous parasitic and exogenous pathogenic nucleic acids, and regulates the expression of protein-coding genes.
What are small ncRNAs?
micro RNA (miRNA)
short interfering RNA (siRNA)
Properties of small non-coding RNA:
Involved in silencing mRNA transcripts.
Called “small” because they are usually only about 21-24 nucleotides long.
Synthesized by first cutting up longer precursor sequences (like the 61nt one that Lee discovered).
Silence an mRNA by base pairing with some sequence on the mRNA.
Discovery of siRNA?
The first small RNA:
In 1993 Rosalind Lee (Victor Ambros lab) was studying a non- coding gene in C. elegans, lin-4, that was involved in silencing of another gene, lin-14, at the appropriate time in the
development of the worm C. elegans.
Two small transcripts of lin-4 (22nt and 61nt) were found to be complementary to a sequence in the 3' UTR of lin-14.
Because lin-4 encoded no protein, she deduced that it must be these transcripts that are causing the silencing by RNA-RNA interactions.
Types of RNAi ( non coding RNA)
MiRNA
Length (23-25 nt)
Trans acting
Binds with target MRNA in mismatch
Translation inhibition
Si RNA
Length 21 nt.
Cis acting
Bind with target Mrna in perfect complementary sequence
Piwi-RNA
Length ; 25 to 36 nt.
Expressed in Germ Cells
Regulates trnasposomes activity
MECHANISM OF RNAI:
First the double-stranded RNA teams up with a protein complex named Dicer, which cuts the long RNA into short pieces.
Then another protein complex called RISC (RNA-induced silencing complex) discards one of the two RNA strands.
The RISC-docked, single-stranded RNA then pairs with the homologous mRNA and destroys it.
THE RISC COMPLEX:
RISC is large(>500kD) RNA multi- protein Binding complex which triggers MRNA degradation in response to MRNA
Unwinding of double stranded Si RNA by ATP independent Helicase
Active component of RISC is Ago proteins( ENDONUCLEASE) which cleave target MRNA.
DICER: endonuclease (RNase Family III)
Argonaute: Central Component of the RNA-Induced Silencing Complex (RISC)
One strand of the dsRNA produced by Dicer is retained in the RISC complex in association with Argonaute
ARGONAUTE PROTEIN :
1.PAZ(PIWI/Argonaute/ Zwille)- Recognition of target MRNA
2.PIWI (p-element induced wimpy Testis)- breaks Phosphodiester bond of mRNA.)RNAse H activity.
MiRNA:
The Double-stranded RNAs are naturally produced in eukaryotic cells during development, and they have a key role in regulating gene expression .
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
2. Micro organisms are the living beings which we
cant see with our naked eyes they are too small
which is in size of micrometers .
They are only seen in a powerful microscope
They are also called as (‘Microbes’)
There are six types they are
Fungi
Algae
Bacterium
Archaea
Virus
Protozoa
3. FUNGI
Fungi are the microbes they grow on
dead/decaying matter
They release their microscopic threads called
(‘Hyphae’) and spread some digestive
chemicals called (‘Spores’)
4. ALGAE
Algae are the microbes which grow in water
they are essential to earth they produce oxygen
There are around 27,000 types of algae
They are first living species on earth which have
respiration
5. BACTERIUM
These are the microbe groups which may
cause diseases or they may be useful
They are unicellular organism
They may be spherical or spiral or few micro-
meters long tube shape
They are located everywhere in the world
6. ARCHAEA
These microbes are prokaryotes, meaning they
have no cell nucleus. Archaea were initially
classified as bacteria, receiving the name
archae bacteria, but this classification is
outdated.
7. VIRUS
Virus are the microbes which interlink between
living and non living things
They act as living organisms when they entered
the cell when they are out side of cell they act
as non living things
They are 6 types of viruses they are HIV , Ebola ,
Hepatitis-B , Adenovirus , Influenza ,
Bacteriophage
8. PROTOZOA
Protozoa are the microbes which is single-
celled eukaryotes, either free-living or parasitic,
which feed on organic matter such as other
microorganisms or organic tissues and debris
9. FACTS
Some areas in Indian ocean bright in night
times because of algae which release light
called ‘Dinoflagellata’ .
Human bytes is one of the most dangerous
bytes because of bacteria present in our teeth
