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Smokers who switch to e-cigarettes greatly reduce their
exposure to carcinogens and other toxic inhaled substances,
according to a British study released Monday.
The study of 181 smokers and former smokers was the first to
directly measure and compare levels of these substances in
people, its authors said. The harm reduction depends on a total
substitution of e-cigarettes for smoking, the study stated.
Previous studies have been performed on cell cultures or
animals, or measured substance levels in e-cigarette vapor.
While these proxy measurements are useful, direct
measurements in people provide superior knowledge of the risks
incurred.
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Researchers analyzed the saliva and urine of long-term smokers,
as well as that of e-cigarette users, called vapers, and users of
nicotine replacement therapies, or NRTs. They measured levels
of TSNAs (tobacco-specific nitrosamines) and VOCs (volatile
organic compounds), established risk factors for smoking-related
diseases.
The study was published in the Annals of Internal Medicine. It
can be found at j.mp/ecigrisk.
Four other researchers who didn’t take part in the study said it
added to evidence that e-cigarettes are less harmful than
smoking. But they differed on its significance.
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American public health organizations have generally opposed
vaping, even as an aid to quitting smoking. They say evidence is
lacking that e-cigarettes are effective, and endorse alternative
methods of quitting, such as nicotine patches or gum. And they
say non-smokers may take up vaping under the mistaken belief
that it’s harmless.
Meanwhile, the U.S. Food and Drug Administration is imposing
strict new rules on e-cigarettes, classifying them as tobacco
products. The e-cigarette liquids vaporized contain no tobacco.
The e-cigarette industry says these rules would add so much
expense that smaller makers would fold, leaving the market to
the big vendors, who happen to be tobacco companies.
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But British public health agencies have generally endorsed e-
cigarettes as being far less risky than conventional cigarettes,
and useful for smokers trying to quit. They embrace an
approach called harm reduction that endorses lessening risk.
Since there is widespread agreement that e-cigarette “vaping”
poses less of a risk than smoking, they say smokers should be
encouraged to try vaping.
Last spring, the Royal College of Physicians approved vaping for
smokers, saying that e-cigarettes have been shown to be
effective for smoking cessation.
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Where danger lies
While nicotine is the addictive drug in cigarettes, it’s not the
most harmful one. Researchers are even studying the use of
nicotine to help against certain neurodegenerative illneses,
such as Alzheimer’s and Parkinson’s diseases.
The real danger of cigarettes lies in the other substances
carried in smoke, include those produced by combustion. The
threats include lung diseases, including cancer, and
cardiovascular disease. The study paid particular attention to
the risk for cancer.
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The level of dangerous chemicals found in solo e-cigarette users
was found to be a fraction of that in solo smokers of regular
cigarettes, expressed in percentages.
● — 2.5 percent the level of TSNAs
● — 33.3 percent for acrolein
● — 42.9 percent for acrylamide
● — 2.9 percent for acrylonitrile
● — 11.0 percent for 1,3-butadiene
● — 43.5 percent of ethylene oxide, acrylonitrile and vinyl
chloride.
But e-cigarette users were found to have 126.9 percent of
nicotine or equivalent of smokers.
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These numbers were reported at a 95 percent confidence level.
The four researchers interviewed for this article agreed that e-
cigarettes are less hazardous than smoking. But they disagreed
on the study’s significance.
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David W. Bareham, a specialist respiratory physiotherapist in
England, cautiously endorsed the study, while emphasizing that
it has limitations.
The study indicates that a total switch from cigarettes to vaping
should significantly reduce the risk from cancer, all else being
equal, said Bareham, of Lincolnshire Community Health Services
near Nottingham, England.
But the study’s findings related to cancer don’t address other
potential harms from e-cigarette use, Bareham said by email.
Moreover, more work is needed to reduce potentially harmful
chemicals in e-cigarette vapors.
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“This new study under review here, though helpful, is only part of the
puzzle that is e-cigarettes,” Bareham said.
“Further, long term studies, following e-cigarette users for a
prolonged period of time, tracking not just issues mostly related to
cancer, but other specific respiratory and cardiac risks, are still
required, before anyone can confidently claim that the harmful
effects of switching purely to e-cigarettes are ‘minimal’ . . . .”
“CDC data demonstrates, importantly, that basically as many people
die from the cardiovascular effects of smoking tobacco as from cancer
effects, so, if we then add on the premature deaths of the non-cancer
lung disease, it becomes clear that the health effects of smoking are
much more than those purely related to cancer,” Bareham said.
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Dr. Michael Siegel, a tobacco control specialist at Boston University who
supports e-cigarettes for smoking cessation, was enthusiastic about the
findings.
“This study adds to the abundant evidence that e-cigarettes are much
safer than real tobacco cigarettes,” Siegel said by email. “In fact, for
the four carcinogens and two toxins tested, levels in e-cigarette users
were comparable to those in nicotine patch users and much lower than
in cigarette smokers. The study also showed that dual use of cigarettes
and e-cigarettes did not significantly reduce exposure to these 6
chemicals.”
Siegel said the study “suggests that benefits in terms of cardiovascular
disease and cancer will only occur if a smoker switches to vaping
completely.”
“The bottom line of this study is that there is now no scientific
uncertainty: vaping is much safer than smoking,” Siegel said.
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Laura Crotty Alexander, M.D. a UC San Diego researcher and
pulmonologist, said by email that the study is “a nice addition” to
existing research.
“These data are reassuring in that e-cigarette users have lower urine
levels of nitrosamines and volatile organic compounds (VOCs), which
are two types of chemicals that are found in the urine of
conventional tobacco smokers, and contribute to the development of
tobacco related diseases,” Crotty Alexander said. “Thus, these data
suggest that e-cigarettes are far less dangerous than smoking
conventional cigarettes.”
Crotty Alexander said caution is still needed, because the long-term
health effects of regular e-cigarette use have yet to be determined.
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“These researchers were specifically looking at levels of
chemicals known to be a problem in tobacco smoking, which is
an excellent starting point for evaluating the safety of e-
cigarettes,” she said. “However e-cigarette vapor is very
different than tobacco smoke, and thus effects on human health
may not mirror those seen with tobacco use.”
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UCSD researcher Wael Al-Delaimy, M.D., said by email that the
study didn’t find anything significantly new.
“We all know that using only e-cigarettes is less harmful than
using combustion cigarettes for the simple reason that
combustion of tobacco is what produces the carcinogens,” said
Al-Delaimy, UCSD’s division chief of global health in the
department of family medicine and public health.
E-cigarettes have been documented to produce close to 50
percent of the harm from regular cigarettes, he said, because of
the effect on the cardiovascular and respiratory systems.
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“The authors just brushed aside that impact and focused on the
lower carcinogens from tobacco,” Al-Delaimy said.
“Nevertheless if a smoker has a choice between smoking a
cigarette or an e-cigarette, of course it is better to use e-
cigarettes as the less harmful choice.”
Al-Delaimy said he was especially concerned that smokers
generally don’t find e-cigarettes helpful in quitting, especially
in the United States.
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“Further, there is clear evidence that non-smokers are starting
e-cigarettes (especially young adults and teens) because of the
publicity and novelty of e-cigarettes. The paper does not
address nonsmokers who use e-cigarettes compared to
nonsmokers who do not use any e-cigarettes to see the
chemicals they are being exposed to (other than the
carcinogens, such as flavoring chemicals).
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“More importantly, the paper shows that those who use both
combustion cigarettes and e-cigarettes actually have higher
levels of these carcinogens which is counter to the belief of the
e-cigarette and vaping advocates that using e-cigarettes will
help cut down combustion cigarette use. It is indicating the
opposite, and this is consistent with studies we have published
and others, that using e-cigarettes is making it more difficult
for smokers to quit. The authors don’t point to this problem and
try to justify it otherwise.
“In this paper the former smokers who now use only e-
cigarettes is a positive outcome, but what is their proportion in
the real world of smokers? Not a substantial one I am afraid,”
Al-Delaimy said.
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18. Contact Details
MI Vape Shops Near Me
Lansing, MI 48933
info@vapeshopsnearme.mi
https://vapeshopsnearme.co/mi
https://goo.gl/maps/4RquxQD6K1s
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