The document discusses medications commonly used during pregnancy and their potential effects on the developing fetus. It covers how drugs cross the placental barrier, the stages of fetal development and vulnerability to birth defects. Various drug categories from A to X are defined based on safety evidence. Specific drugs that are teratogenic like isotretinoin and anticonvulsants are examined, outlining the fetal abnormalities linked to their use during pregnancy. The document emphasizes that unless absolutely necessary, medications should be avoided during pregnancy due to risks of harming the fetus.