This document discusses different ways of measuring health, including natural measurements like healthy days and quality-adjusted life years (QALYs) and disability-adjusted life years (DALYs). It describes how QALYs quantify both the quality and quantity of life by assigning weights between 0 and 1 to different health states. Methods for estimating these weights include rating scales, time trade-off, and standard gambling. The document also discusses instruments like the EQ-5D that are used to measure health-related quality of life and provide weights to calculate QALYs and QALY gains from interventions.