This study examined the effects of creatine monohydrate supplementation combined with a resistance training program on muscular strength. The study reviewed previous research that found creatine supplementation improved muscular strength during high-intensity exercise by generating ATP. This double-blind placebo controlled study tested the effects of 5 grams per day of creatine monohydrate supplementation over 4 weeks combined with a resistance training program. Results showed significant increases in bench press, leg press, arm flexor, and vertical jump strength in the creatine groups compared to the placebo groups. The findings support that creatine supplementation increases muscular strength when combined with resistance training.