Marketo allows users to manage leads by creating, searching, and assigning leads to queues. The document outlines the steps to: 1) Create a lead in Marketo by entering required fields like name and email; 2) Use Quick Find to search for a lead by name; and 3) Assign the lead to a marketing queue in Salesforce using a sync action in Marketo. It also describes how to view the lead status and search results in both Marketo and Salesforce to confirm the lead was properly synced between the systems.