With the pandemic overclouding the whole world it has effected every strato of people including the Orthopaedic groups. This is to highlight the impact of COVID 19 on the orthopaedic in general.
a simplified version of periprosthetic fractures, easy to learn and understand with lots of images and classification. It includes hip, shaft of femur, knee, shoulder
Can read freely here
https://sethiortho.blogspot.com/
Damage control &
Early Appropriate care in Orthopedics
ContentsEvolution of poly trauma management
Early total care
Damage control orthopedic care
Early appropriate care
Introduction
Trauma is the leading cause of death in young populatio
Immediate death – 50%- minutes
Lethal head injury
Hemorrhagic shock
Early death - 30%- hrs
Secondary brain injury
Hemorrhagic shock
Late death – 20% - days to weeks
ARDS
Pneumonia
MODS
Damage control surgery
Evolution of Polytrauma Management
Management concept - Delayed management
Splints, casts and traction
Definite surgery delayed for 10 -14 days
Prolonged bed rest and hospital stay
Damage control surgery
Decubitus ulcer
Disuse atrophy
Early definitely stabilization long bone fracture reduced incidence of fat embolism syndrome
Early Total Care
Damage control surgery
Usually within the first 24hrs
Early Total Care - Advantages
Early fixation favors skin and soft tissue healing
Prevent ongoing tissue damage
Pain relief
Improve joint function
Early mobilization
Respiratory distress
Pneumonia
Early stabilisation of hemodynamically unstable or/and had concomitant chest or head injury patients develop high mortality
mainly by ARDS and MODs
Reasons for the high mortality ?
Two hit phenomena
These findings indicated that
ETC is not appropriate for unstable poly trauma patients
Damage control surgery
Damage control is a new term first used by the US Navy during World War II to describe emergency measures for control of flooding that threatens to sink a ship.
Goal is to ensure survival of the ship until it reaches a port where definitive repairs can be safely performed.
Basic strategies of DCO -
Control of haemorrhage
Damage control surgery
Minimize the second hit
Immediate and rapid stabilization of long bone fractures - EF
Release of tight soft tissue compartments
Reductions of dislocations
Surgical debridement of open wounds
Amputation, in cases of unsalvageable extremities
Definitive fixation is later
Immediate external fixation followed by early closed intramedullary nailing is a safe treatment method for fractures of the shaft of the femur in selected polytrauma patients.
Which patient need DCO approach ?
Patients who have sustained orthopedic trauma have been divided into four groups:
Damage control surgery
Patient categorization
Limitations of DCO
Axial skeleton and femoral fractures
No external fixation
Even ex fix , patient mobilization is poor - bed ridden condition
Anatomical reduction favours pain relief, soft tissue healing and muscle function
Limitations of DCO
Classification of patient condition is not static, dynamic and changed with resuscitation
DCO recommended for those patients who are unstable or in extremis however the optimal time and type of treatment, who are in border line remain controversial
Distal femur fractures what makes it complex ,dr mohamed ashraf,hod orthopae...drashraf369
distal femur fractures are notorious for post operative complications due to malreduction and improper fixation.unless plan and execute a sound and stable fixation,this injury will lead to undesirable results.dr mohamed ashraf HOD orthopaedics govt TD medical college is presenting how to avoid complications in surgical management of these fractures..
With the pandemic overclouding the whole world it has effected every strato of people including the Orthopaedic groups. This is to highlight the impact of COVID 19 on the orthopaedic in general.
a simplified version of periprosthetic fractures, easy to learn and understand with lots of images and classification. It includes hip, shaft of femur, knee, shoulder
Can read freely here
https://sethiortho.blogspot.com/
Damage control &
Early Appropriate care in Orthopedics
ContentsEvolution of poly trauma management
Early total care
Damage control orthopedic care
Early appropriate care
Introduction
Trauma is the leading cause of death in young populatio
Immediate death – 50%- minutes
Lethal head injury
Hemorrhagic shock
Early death - 30%- hrs
Secondary brain injury
Hemorrhagic shock
Late death – 20% - days to weeks
ARDS
Pneumonia
MODS
Damage control surgery
Evolution of Polytrauma Management
Management concept - Delayed management
Splints, casts and traction
Definite surgery delayed for 10 -14 days
Prolonged bed rest and hospital stay
Damage control surgery
Decubitus ulcer
Disuse atrophy
Early definitely stabilization long bone fracture reduced incidence of fat embolism syndrome
Early Total Care
Damage control surgery
Usually within the first 24hrs
Early Total Care - Advantages
Early fixation favors skin and soft tissue healing
Prevent ongoing tissue damage
Pain relief
Improve joint function
Early mobilization
Respiratory distress
Pneumonia
Early stabilisation of hemodynamically unstable or/and had concomitant chest or head injury patients develop high mortality
mainly by ARDS and MODs
Reasons for the high mortality ?
Two hit phenomena
These findings indicated that
ETC is not appropriate for unstable poly trauma patients
Damage control surgery
Damage control is a new term first used by the US Navy during World War II to describe emergency measures for control of flooding that threatens to sink a ship.
Goal is to ensure survival of the ship until it reaches a port where definitive repairs can be safely performed.
Basic strategies of DCO -
Control of haemorrhage
Damage control surgery
Minimize the second hit
Immediate and rapid stabilization of long bone fractures - EF
Release of tight soft tissue compartments
Reductions of dislocations
Surgical debridement of open wounds
Amputation, in cases of unsalvageable extremities
Definitive fixation is later
Immediate external fixation followed by early closed intramedullary nailing is a safe treatment method for fractures of the shaft of the femur in selected polytrauma patients.
Which patient need DCO approach ?
Patients who have sustained orthopedic trauma have been divided into four groups:
Damage control surgery
Patient categorization
Limitations of DCO
Axial skeleton and femoral fractures
No external fixation
Even ex fix , patient mobilization is poor - bed ridden condition
Anatomical reduction favours pain relief, soft tissue healing and muscle function
Limitations of DCO
Classification of patient condition is not static, dynamic and changed with resuscitation
DCO recommended for those patients who are unstable or in extremis however the optimal time and type of treatment, who are in border line remain controversial
Distal femur fractures what makes it complex ,dr mohamed ashraf,hod orthopae...drashraf369
distal femur fractures are notorious for post operative complications due to malreduction and improper fixation.unless plan and execute a sound and stable fixation,this injury will lead to undesirable results.dr mohamed ashraf HOD orthopaedics govt TD medical college is presenting how to avoid complications in surgical management of these fractures..
Hoffa's Fracture: Diagnosis, management & New Classification System by BAGARI...Vaibhav Bagaria
Hoffa's Fracture - coronal split fracture of distal femur, its diagnosis, management strategy, a new classification and tips and tricks of management. First described Hoffa, a new classification system by Bagaria et al helps plan the surgery for these tricky fracture. The most crucial step is not to miss these fractures in ER.
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
Periprosthetic fractures are the third most common reason for revision total hip arthroplasty. Surgical treatment of periprosthetic fractures belongs to the most difficult procedures due to the extensive surgery, elderly polymorbid patients and the high frequency of other complications. The aim of this study was to evaluate the results of operatively treated periprosthetic femoral fractures after total hip arthroplasty.
Orthodontic management of patients during covid 19Shrutika Chand
A brief knowledge of how to deal with patients during COVID-19. Safety measures and about the cases which falls under the category of "Dental emergencies"
Hoffa's Fracture: Diagnosis, management & New Classification System by BAGARI...Vaibhav Bagaria
Hoffa's Fracture - coronal split fracture of distal femur, its diagnosis, management strategy, a new classification and tips and tricks of management. First described Hoffa, a new classification system by Bagaria et al helps plan the surgery for these tricky fracture. The most crucial step is not to miss these fractures in ER.
Deformity: It’s the position of a limb/Joint, from which it cannot be brought back to its normal anatomical position.
Described as abnormalities of :
Length
Angulation
Rotation
Translation
Combination
Periprosthetic fractures are the third most common reason for revision total hip arthroplasty. Surgical treatment of periprosthetic fractures belongs to the most difficult procedures due to the extensive surgery, elderly polymorbid patients and the high frequency of other complications. The aim of this study was to evaluate the results of operatively treated periprosthetic femoral fractures after total hip arthroplasty.
Orthodontic management of patients during covid 19Shrutika Chand
A brief knowledge of how to deal with patients during COVID-19. Safety measures and about the cases which falls under the category of "Dental emergencies"
The world is witnessing an invasion from a new corona virus, which resulted in more than one million of deaths. Most of the sectors such industrial, economy, and tourism are facing a crisis, hence the workers in the field of medicine, considered to be the barrier to fight this invasion. This new virus seems to have two main transmission routes: direct and contact, which it will open a high chance of infection among professional health providers, especially, surgeons and dentists. Maxillofacial and dental surgeons, considered to be essential professional health experts that perform, multiple surgeries and dental procedures every day, consequently, these professions will exhibit a high risk of getting infected by Covid19, due to that, this review article aimed to discuss the possible ways that it may help in optimizing the level of infection control.
Anesthesiologist’s Prospective on Self-protection, Therapy, and Managements i...asclepiuspdfs
During the beginnings of 2020, a virus has spread from China and caused a huge surge in severe acute respiratory cases globally. Due to the high contagiousness and anomalous course of severe acute respiratory syndrome coronavirus 2, caused by coronavirus disease, abbreviated as COVID-19, the World Health Organization (W.H.O) announced it as a pandemic and strict measurements were implemented to try and protect the vulnerable populations and those fighting on the frontline of this wave.[1] Scientific personnel all over the world began reviewing hundreds of articles published by scientific authors about the preexisting coronaviruses to assess the strain and pathogenesis of COVID-19 and explore possible effective therapies. At the beginning of the pandemic, the goal was clear: Support the immune system by using preexisting drugs such as antibiotics and antivirals to prevent superinfections and alleviate possible foreseen complications, in addition to the use of prophylactic vaccines in high-risk groups. Another therapy option was the use of convalescent sera, which is a passive antibody therapy used as prophylaxis.[2] In this review, we conclude the importance of adhering to the precautionary guidelines set by the W.H.O recommended for health care workers and the general population, as the most important factor for protection against further transmission of the virus. The extra respiratory manifestations of the virus will also be highlighted along with the therapy modalities that are already being used and the upcoming vaccines that will counteract the virus.
Standard Operative Procedures of Imaging Departments amid Coronavirus Disease...asclepiuspdfs
Radiology preparedness to fight the pandemic coronavirus disease 2019 (COVID-19) is a set of policies and procedures directly applicable to imaging departments designed to achieve sufficient capacity for continued operation during a health-care emergency of unprecedented proportions as it is evident from exponential rise in the cases worldwide and to provide support the care of patients with COVID-19. This standard operative procedure will also be helpful in maintaining the radiologic diagnostic and interventional services to the health system.
Prevention of infection in dental clinic in COVID-19Prachi Jha
PREVENTION OF INFECTION IN DENTAL CLINIC DURING COVID 19 PANDEMIC IN ACCORDANCE WITH GUIDELINES ISSUED BY MOHFW, CDC, IDA, DCI AND IT'S APPLICATION WITH AN ENDODNOTISTS'S POINT OF VIEW
Hospital care in Department define as Covid-free: A proposal for a safe hospi...Valentina Corona
Hospital care in Department define as Covid-free: A proposal for a safe hospitalization protecting helathcare professionals and patients not affect by Covid-19
Resilience strategy in emergency medicine during the Covid-19 pandemic in ParisOceane MINKA
This study describe the organizational impact of the Covid-19 pandemic in Emergency Medicine. Published in JEUREA : https://doi.org/10.1016/j.jeurea.2021.04.001
The 68-page Handbook of Covid-19 Prevention and Treatment provides guidelines and practices by China’s top experts for coping with the disease. It is prepared by the First Affiliated Hospital of Zhejiang University’s School of Medicine which has treated 104 confirmed patients over the past 50 days with no medical staff infected, according to the handbook. Zhejiang, home of Alibaba, had a cumulative 1,215 confirmed Covid-19 cases, out of a population of 57 million people
, with one death from the pandemic.
Handbook of COVID-19 Prevention and Treatment -Linor Auto Parts Factory Linor Auto Parts Factory
Faced with an unknown virus, sharing and collaboration are the best remedy.
The publication of this Handbook is one of the best ways to mark the courage and wisdom our
healthcare workers have demonstrated over the past two months.
Thanks to all those who have contributed to this Handbook, sharing the invaluable experience
with healthcare colleagues around the world while saving the lives of patients.
Thanks to the support from healthcare colleagues in China who have provided experience that
inspires and motivates us.
Similar to Management of orthopaedic patients during covid‑19 pandemic (20)
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journey
Management of orthopaedic patients during covid‑19 pandemic
1. Management of Orthopaedic Patients
During COVID-19 Pandemic
in India: A Guide
Moderator : Dr. E.Venkateshulu
Professor and Unit Chief
Dpt. Orthopedics, VIMS, Ballari
Presenter : Dr. Punith Kumar P.C
2. Introduction
Coronaviruses are a group of viruses that mainly affect
human beings through animal transmission. It is the
third time, the emergence of novel coronavirus in last
two decades,
Severe acute respiratory syndrome (SARS) in 2003
Middle East respiratory syndrome coronavirus
(MERSCoV) in 2012
Novel severe acute respiratory syndrome coronavirus
(SARS-CoV-2)-infected pneumonia (COVID-19).
3.
4. Novel severe acute respiratory syndrome coronavirus
(SARS-CoV-2)-infected pneumonia (COVID-19)
o The novel coronavirus first emerged in Wuhan, China in
December 2019 from the wet seafood market. COVID-19
was regarded as a public health emergency of international
concern in the world by mid-February 2019.
o The epicentre of the pandemic shifted from Europe to USA
from time to time and at present there are around 17.8 lakh
cases of COVID-19 with 109,275 casualties in the world,
amounting to 6.12% mortality rate according to World Health
Organization (WHO) as of now.
5. o India is a developing country with around 1.3 billion population,
2nd largest in the world after China.
o In India, there is one allopathic doctor per 10,926 population ,
which is below WHO’s recommendation of 1:1000, putting
tremendous pressure on the health care system in India due to
COVID-19. The first case of COVID-19 was reported on 30th
January 2020 and the number has reached 8500 as on 12th April
20, with 289 deaths.
o On 25th March 2020, Prime minister of India announced a
nationwide 3-week lockdown to prevent community transmission
in India. This lockdown has been extended further and we have no
idea when this lockdown gets released.
6. o Even after the release of lockdown, the situation will not be
the same as in the past and we have to be more careful in
attending patients. The hospitals are becoming hot zones for
the treatment as well as transmission of COVID-19 due to a
rise in the community transmission from Europe, Asia and the
rest of the world.
o Orthopaedic surgeries including both elective and emergency
procedures (trauma patients) require operation theatres which
are high-risk areas for transmission of COVID-19, risks
health care workers contracting this illness and decreasing the
resources available to the population of India during this
pandemic.
7. o The high prevalence of COVID- 19, limited resources and
staff, increased risks of transmission and the burden on health
systems during this pandemic; keeping all this in mind, the
health system must act immediately and support essential
surgical care while protecting patients and staff and
conserving valuable resources.
8. COVID-19
Coronaviruses are positive-sense RNA viruses having an
extensive and promiscuous range of natural hosts and affect
multiple systems. Coronaviruses can cause clinical diseases in
humans that may extend from the common cold to more
severe respiratory diseases like SARS and MERS.
The recently emerging SARS-CoV-2 has wrought havoc in
China and caused a pandemic situation in the worldwide
population, leading to disease outbreaks that have not been
controlled to date, although extensive efforts are being put in
place to counter this virus.
9. This virus has been proposed to be designated/named severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by
the International Committee on Taxonomy of Viruses (ICTV),
which determined the virus belongs to the Severe acute
respiratory syndrome-related coronavirus category and found
this virus is related to SARS-CoVs. SARS-CoV-2 is a
member of the order Nidovirales, family Coronaviridae,
subfamily Orthocoronavirinae,
10. Naming the coronavirus disease (COVID-19)
and the virus that causes it
Official names have been announced for the virus responsible
for COVID-19 (previously known as “2019 novel
coronavirus”) and the disease it causes. The official names
are:
Disease
coronavirus disease
(COVID-19)
Virus
severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)
14. Orthopaedic Patients Expected During
Lockdown Period
Trauma.
History of fall at home, the neck of femur
fracture in elderly.
History of assault.
Severe cervical or lumbar pain.
Post-operative cases for wound dressing or
suture removal.
Postoperative surgical site infections.
Elective cases with severe symptoms.
15. Steps to Create a Safe Working
Environment
1. Ensure Safe Working Environment
The examination area in the emergency especially door handles,
working stations and frequently used items should be cleaned
regularly at least four times a day with 1% hypochlorite/lysol.
Ensure that the healthcare staff including the doctor, nurses and
paramedical staff have no signs and symptoms related to COVID-19
infection or any contact with COVID patients in the past 14 days
and it is better to screen the health care staff, if feasible.
All health care staff should wear a personal protective equipment
(PPE) in the emergency, if not at least wear an N-95 mask, a
surgical gown and examination gloves and shoe covers. Education
of health care staff, patients and their attendants should be of utmost
priority.
16. 2. How to Attend Patients?
A three-layer surgical mask, hand sanitizer and a disposable
glove box should be available at the entry point of the
emergency area for patients and their attendants. In case of
trauma, it might be not possible to wear a mask for the patient
in all cases, at least ensure that attendants are provided with
one.
History of COVID-19 like symptoms and any history of
contact should be obtained both from patient and attendant
and a separate perform should be attached to record all
information.
17. If there is any positive history then isolate both patient and attendant
and treat as COVID positive unless proved otherwise. It is better to
keep every patient in isolation and convert every ward to isolation
rooms as there will be a limited number of patients in inpatient
departments (IPD). Maintain a separate dressing room and plaster
room for patients and waste like dressing material, gauges etc. of
suspected patients should be disposed of carefully.
18. 3. Avoid Negligence Towards Elective Patients
with Severe Symptoms
Every symptom should be recorded carefully and one should not be
negligent towards elective patients. Patients with tumour or
pathological fracture, or cauda equina or any infection should be
investigated properly and surgical intervention should be deferred
unless it is required on an urgent basis.
We may also have cases like avascular necrosis/ ankylosing hips or
rheumatoid knee where patients present with severe pain, adequate
analgesia should be given to get rid of acute symptoms.
19. 4. How to Manage a Trauma Patient with COVID-19-Like Symptoms?
(Having Signs or History of Contact)
Inform hospital administration authority, CMO or SMO. A specialized
COVID area in the triage should be ready for COVID-19 patients with
trauma. Resuscitate the patient with a primary survey along with
splintage of fracture limb. All necessary pre-operative investigations
along with COVID- 19 testing should be done.
If possible, get portable X-rays and ultrasound to avoid contamination
of the radiology area and it also helps in decreasing movement of
COVID patients. For investigations like CT scan or MRI, we have to
sterilize the respective area after investigating every patient as per
centres for disease control and prevention.
20. Patients with closed fractures should wait for surgical interventions
until the COVID-19 results are out. All cases which need urgent
management like an open fracture, vascular injuries, compartment
syndrome or mangled limb; we cannot wait until COVID results.
These patients should be managed as COVID positive patients and
strict precautions should be taken to avoid transmission to
caregivers or to other patients.
If the results are positive keep the patient in the COVID isolation
ward until the results are negative and take the help of the COVID
response team of the hospital. If the results are negative shift the
patient to the orthopaedic ward and then discharge as early as
possible.
21. Guidelines for management of non COVID patients
(standard protocol) and COVID positive patients
(COVID protocol).
24. Standard Protocol
1. Resuscitate patient, rule out all other injuries (Primary
survey).
2. High chances of missed injuries in light of COVID suspicion
(Secondary survey).
3. Manage conservatively whenever possible.
4. Keep patients in isolation wards. Provide patients and
attendants with masks. Minimize patient and attendants’
movements. Expedite the process of operation and discharge
to lessen the load over the health system. These
patients should be attended by separate team surgeons.
5. Maintain a follow up OPD in a separate area for dressing,
suture removal and Plaster removal.
25. COVID Protocol
1. Manage conservatively whenever possible.
2. From the triage area patients (separate allocated area
for COVID) should be shifted to the operating room.
3. Strict regulations must be maintained while shifting the
patients. Sterilize all things that used while shifting,
viz. trolley, lift etc.
4. Maintain a dedicated COVID operating room with
trained staff.
5. Preventive measures must be followed at every level.
26. 6. Every effort should be made to minimize the duration of
surgery.
7. Decrease blood spilling.
8. Proper disposal of surgical waste.
9. Maintain negative pressure ventilation.
10.Patients have to be shifted to dedicated COVID isolation
wards postoperatively and discharged only after COVID
results are negative.
11.Care must be taken during the hospital stay to physiotherapy,
bedsores and DVT prevention.
27. Flowchart for dealing with orthopaedic and Trauma
cases during the period of the COVID-19 Pandemic.
28.
29. Examples for Recommendations for Orthopaedic Paediatric Trauma
Management during COVID-19 pandemic
Injury What to do immediately Follow up
Gartland 1 Supracondylar
fracture
Collar and cuff, removed
by family at 3 weeks.
None required.
Fibular Fracture Apply walking boot
Weight bear as tolerated
Family to remove boot at
week 4
Teleconference week 6
30. Example Management Rationale Follow-up
New case of a
club foot
Do not start a
Ponseti
casting
Ponseti method
requires frequent
reviews,
risk of
transmission
Ponsetti casting
can be
commenced later
Review after
COVID
pandemic (3
months)
Consider
teleconferencing
Anterior Cruciate
Ligament
Postpone Excellent results
can be still
obtained
with a period of
delay
Follow-up after
the pandemic.
Offer prehab
program.
31. Peri-operative precautions when
operating on a COVID-19 positive or
suspected case
This should be incorporated into hospital plans and rules to
face the pandemic, and can be subdivided into measures
involving
The operating room,
Personnel,
Anaesthesia,
The procedure,
Postoperative precautions.
32. Operating room measures
o Separate operating rooms (OR) should be designated for COVID-19
positive patients, isolated from other operating rooms. The
operating room is preferred to have a separate ventilation system
with negative pressure, which if not available, it is recommended to
add High-Efficiency Particulate Air (HEPA) filters to positive
pressure rooms.
o Moreover, Air conditioning should be turned off. Only the materials
necessary for the case should be brought into the OR. All equipment
and screens should be covered with plastic sheets to facilitate
decontamination. Consider attenuation of residual environmental
contamination through cleaning with surface disinfectants and
ultraviolet light (UV-C).
33. o All traffic in and out of the OR should be minimized. All doors
should be closed once the patient is transferred in and during the
whole operation. The path of the patient to and from the OR should
be kept clear and better to be separate from other operating rooms.
Patients should cover their face with a surgical mask.
o The patient should recover in the operating room and transferred
directly to the isolation ward . The number of personnel inside the
OR should be kept to the minimum. Services personnel should not
enter the room until enough time has elapsed for air changers to
reduce the risk of contamination. Sales representatives, residents,
and fellows should be discarded from OR unless essential.
34. Operating personnel
o The fewest number of personnel possible is the main goal, with the
highest skilled surgeon performing the procedure to avoid
prolongation of the surgery.
o All personnel in the operating room should wear the PPE which
include Association of Advancement of Medical Instrumentation
(AAMI) level III surgical gowns, surgical hood (for head and neck
covering), double gloves, facemasks and either N95, Filtering Face
Piece 2 (FFP2) respirators with a face shield/googles or Powered
Air-Purifying Respirator (PARP), fluid-resistant shoes or booties.
35. o Donning and doffing of PPE should be done in an anteroom if
available, with hand hygiene prior and after donning/doffing PPE.
o Avoid self-contamination during PPE doffing. Disinfect the first
pair of gloves with an alcohol solution, before removing the surgical
mask with the shield and the hair cap. Consider placing a simple
surgical mask on top of the N-95 to prevent gross contamination.
Each time N95 respirator is taken off, it must be double-checked for
not being soiled or damaged before reuse. Full face shield is
preferred to protective eye goggles.
36. Consideration of PPE for
Orthopaedic surgeon
Confirmed Non-COVID-
19
COVID_19( Status Unknown) COVOD-19
Positive
Minimum
Standard PPE (surgical
masks, eye protection and
gown)
Minimum
Standard PPE
Additional PPE Considerations for
possible aerosolizing orthopaedic
procedures
N95 respirator with full-face shield
or surgical hood
N95 respirator
with full face
shield or surgical
hood
37. Anaesthesia
o Dedicated anaesthesia machines should be exclusively designated
for COVID-19 positive cases. The most experienced
anaesthesiologist should intubate the patient in the shortest possible
time with minimal airway manipulation, avoiding face mask
ventilation and open-air way suction as possible.
o Keep the minimum number of personnel inside the anaesthesia
room which should be separate from the operating room, which
should not be entered for 15–20 min after intubation. Use deep
anaesthesia and neuromuscular blockage.
o Preoxygenation should be performed via well-fitting face mask to
avoid hypoxia in critically ill COVID-19 patients with respiratory
failure. It is preferred to avoid general anaesthesia and use of
regional/spinal anaesthesia is recommended whenever possible.
38. Surgical procedure
o Consider the use of minimally invasive approaches to decrease
operating staff exposure and shorten case duration. Use disposable
medical supplies/instruments whenever possible, and absorbable
sutures for wound closure to avoid a postoperative unnecessary
visit.
o The use of electrocautery should be reduced to minimize the
surgical smoke and should be used in conjunction with a smoke
evacuator. Care should be taken when using sharp objects to avoid
sharp injury or damage of PPE. The use of power tools like bone
saws, reamers, and drills should be reduced to the minimum and the
power settings should be as low as possible, as they release
aerosols, increasing the risk of virus spread. Suction devices to
remove smoke and aerosols should be used during their use.
39. o All body fluids as blood, secretions, urine, or pathological
specimens should be collected in double sealed bags for inspection
or destruction. All contaminated instruments and devices should be
disinfected separately followed by proper labelling.
40. Postoperative precautions
o The transfer to isolation wards should be through dedicated corridors and
elevators which should be carefully sterilized after transport. During the
transfer, transport personnel should wear PPE which should not be the
same as worn during the procedure and patients should be wearing N-
95/FFP2 masks and covered with disposable operating sheets.
o Surgeons must be aware of common postoperative complications from
COVID-19 infections. In the presence of fever and one of the symptoms of
a respiratory infection (dry cough, etc.), laboratory tests for COVID-19
diagnosis must be ordered. Suspected cases should be reported
immediately together with transfer of the patient to an isolation ward.
41. o Patients should receive adequate nutrition, fluid hydration, and
electrolyte balance to promote immune recovery and rapid
rehabilitation. Frequent monitoring of temperature, laboratory
Complete Blood Count (CBC), C-reactive protein, and Ferritin level
should be done.
o Severe COVID-19 infection might cause a “cytokine storm
syndrome”, which is characterized by a fulminant and fatal hyper-
cytokinemia with multiorgan failure. An increased level of ferretin
occurs in approximately 50% of patients. All patients with severe
COVID-19 should be screened for hyper-inflammation markers.
42. DISCUSSION
Patients presented to the emergency triage with an
orthopaedic emergency such as joint dislocations,
compartment syndrome, open fractures, mangled extremity,
polytrauma with FESS should be managed according to a
specific guideline during global health emergencies like a
pandemic of COVID-19.
These orthopaedic emergencies require effective outpatient,
inpatient and surgical care besides avoiding transmission of
infection to fellow patients and health care givers.
43. Low- and middle-income countries in Southeast Asia require
a standard protocol that can be followed throughout the
country with minimum resources available to ease burden
over the health care system.
There are no guidelines published in the past. Hence, this
article can be valuable for the development of a standard
universal guidelines for management these emergencies.
44. The patient attendees should also be screened for the risk
factors and number of visitors to be restricted. Contact tracing
can also be done with the help of these visitors. The
department of Preventive and Social Medicine and COVID
response team should be involved in this regard.
To prevent cross-contamination among fellow residents and
faculty, it’s imperative to have a dedicated orthopaedic team
to manage these suspected or diagnosed COVID-19 patients.
This team should comprise of a junior resident, registrar and
consultant.
45. This team has to manage and follow these patients throughout their
hospital stay including the pre-operative, intra-operative and post-
operative care.
They are not allowed to attend other patients and remain segregated
from the other department colleagues. We need to have 2–3 such
teams who work according to shifts.
They should be advised to wear a triple layer surgical mask
(preferably N-95) and hand hygiene to be maintained with the use of
hand sanitizers and frequent hand washing. They must wear full
PPE and should be taught how to wear and remove PPE effectively.
46. The lesson learned worldwide by orthopaedic surgeons can
benefit India, to stay on top as we plan our approach to
orthopaedic surgery during this pandemic of COVID-19.
One should always remember that we are a doctor before an
Orthopaedician. We should collectively work with other
departments to face this pandemic.
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