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Male Infertility
Infertile Male
Males with sperm parameters below the
WHO standards
Male factor 40%
Female factor 40%
Both 20%
16-18 million new couples / year
Sperm count on the decline
A decade ago 60 million
Now 20 million
Environmental
Lifestyle
Dietary
Congenital
Infection
Occupation
Causes
Pesticides, Chemicals, heavy metals
Air and water pollution
Radiation ‘Cell phone’
Environmental
Smoking
Alcohol
Preservatives ‘fast food’
Genetically Modified food
Hormones
Testosterone and Estrogens
Tight Dress
Life style
Food additives
Protein Supplements
Hormones and Steroids
Varicocele
Body Building
Hypogonodotropic Hypogonadism
Cryptorchidism
Kline felters
Maturation arrest
Sartoli only cell syndrome
Absence of Vas and Seminal vesicles
Congential
Epididymo Orchitis
Mumps
Seminal Vasiculitis
Gu Koch's
Police,Guards, Post men, Sales men
HMT, Athletes and Body Builders
Cooks, Bakery, Foundry, Smithy
Farmers
Drivers-‘Bangalore Bike Riders’
Occupation
Infection
Defective sperms is the most common
cause
Sperm is highly sensitive to
oxygen radicals
Infection
Aging
Environmental
Oxidative stress
Poor Semen is significantly
due to three factors
Oligospermia
Low sperm count < 15 ml
Asthinospermia
Poor motility < 32 %
Teratospermia
Poor morphology <4%
Semen Analysis
Doppler scrotum
TRUS
Vasography
Diagnosis
Varicocele
Dilated Pimpiniform plexus
Increases Testes Temperature
Poor testes function
1O C increase- 14% reduction
Commonest cause of male infertility
15% General population
35% Primary infertile Men
75% Secondary infertile Men
Common among...
People who work standing(Post
Man, salesman, guards, police)
People work hard HMT, Body
builders, Jym goers, sportsman
People work in hot areas
(Smithy, Foundry, cooks, drivers)
Diagnosis
Clinical
Grade 1: Felt on Valsalva
Grade 2: Felt on rest
Grade 3: easily visible
Scrotal Doppler
Improves testicular function 80%
Repair will halt any further damage
Why Surgery
Varicocelectomy
Surgery Varicocele ligation
Scrotal approach: damage to artery PALAMO’S:
High Recurrence
Microsurgical:  Gold standared Best results, least
recurrence,  hydrocele
 Embolisation and Scelrotherapy: High
complications
 Laparoscopic Varicocele ligation
Early surgery Better results
Grade 2­3 better recovery
Microsurgical best results
Least complications
Obstructive Azospermia
Vasectomy
Hernia and Hydrocele Surgery
Chronic Epidimytis
Scrotal injury
Ejaculatory duct obstruction
Genital Koch’s
Vasography
Radiological  study: Obstructive Azospermia
Done at time of corrective surgery.
Complication: Stricture at the puncture site.
Commonest: Ejaculatory duct obstruction
TURED: Ejaculatory duct obstruction
Vaso­vasostomy: Vas obstruction
Vaso­Epididymostomy: Epididymal obstruction
Sperm Retrieval
Sperms retrieved Surgically from
    Vas or testes
Obstructive Azospermia
Poor semen quality
 
    Cryptorchidism
    Klinefelters
    Maturation arrest
PESA
Epididymal
Open Microsurgical
Better results
Percutaneous: Less reliable
Epididymal ducts opened microscopy
Sperms aspirated with pipette
Testes TESA
Failure of PESA
Non Obstructive Azospermia
Testes opened Microscopy
Sperms aspirated from testes tubules
Male Infertility is on rise
Quality of Sperm is down
Environment and Life style
Varicocele commonest cause
Surgery for Obstructive Azo on
decline
Success of sperm retrieval improving
Role of Antoxidents Micro nutrients is
promising
Assisted Reproduction success is on
the raise.

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