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K R MICRO NOTES 1
K R MICRO NOTES 2
K R MICRO NOTES 3
K R MICRO NOTES 4
 In 2018, there were an estimated 228 million cases of malaria
worldwide.
 The estimated number of malaria deaths stood at 405 000 in
2018.
 Children aged under 5 years are the most vulnerable group
affected by malaria; in 2018, they accounted for 67% (272 000)
of all malaria deaths worldwide.
 The WHO African Region carries a disproportionately high
share of the global malaria burden. In 2018, the region was
home to 93% of malaria cases and 94% of malaria deaths.
 Total funding for malaria control and elimination reached an
estimated US$ 2.7 billion in 2018. Contributions from
governments of endemic countries amounted to US$ 900
million, representing 30% of total funding.
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K R MICRO NOTES 33
• Malaria vaccine is a vaccine that is used to prevent malaria. The
only approved vaccine as of 2015 is RTS,S, known by the trade
name Mosquirix. It requires four injections, and has a relatively
low efficacy. The 'R' stands for the central repeat region of
Plasmodium (P.) falciparum circumsporozoite protein (CSP);
the 'T' for the T-cell epitopes of the CSP; and the 'S' for hepatitis
B surface antigen (HBsAg).
K R MICRO NOTES 34

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Malaria Medical Microbiology K R.pptx

  • 1. K R MICRO NOTES 1
  • 2. K R MICRO NOTES 2
  • 3. K R MICRO NOTES 3
  • 4. K R MICRO NOTES 4
  • 5.  In 2018, there were an estimated 228 million cases of malaria worldwide.  The estimated number of malaria deaths stood at 405 000 in 2018.  Children aged under 5 years are the most vulnerable group affected by malaria; in 2018, they accounted for 67% (272 000) of all malaria deaths worldwide.  The WHO African Region carries a disproportionately high share of the global malaria burden. In 2018, the region was home to 93% of malaria cases and 94% of malaria deaths.  Total funding for malaria control and elimination reached an estimated US$ 2.7 billion in 2018. Contributions from governments of endemic countries amounted to US$ 900 million, representing 30% of total funding. K R MICRO NOTES 5
  • 6. K R MICRO NOTES 6
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  • 31. K R MICRO NOTES 31
  • 32. K R MICRO NOTES 32
  • 33. K R MICRO NOTES 33
  • 34. • Malaria vaccine is a vaccine that is used to prevent malaria. The only approved vaccine as of 2015 is RTS,S, known by the trade name Mosquirix. It requires four injections, and has a relatively low efficacy. The 'R' stands for the central repeat region of Plasmodium (P.) falciparum circumsporozoite protein (CSP); the 'T' for the T-cell epitopes of the CSP; and the 'S' for hepatitis B surface antigen (HBsAg). K R MICRO NOTES 34