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Primary Care Conference 
19 Nov 2014 
Role of Research in Primary Care
Overview 
• Strategic context for health research 
• Overview of HRB 
• Primary care research in Ireland 
• Examples of primary care research linked 
to practice
Health Research Plans 
• HRG Action Plan for Health 
Research 2009-2013 
• HRB Strategic Business Plan 
2010 -2014 
• National Research 
Prioritisation Exercise 2012 
Set the strategic direction, goals, 
targets and actions to reap the health, 
social and economic benefits of our 
investment in health research
1. Patient-oriented research 
2. Population Health 
3. Health Services Research 
• Projects 
• Applied Programmes 
• Centres/networks 
• Short courses/workshops 
• Fellowships and Career 
Awards 
• Research Infrastructure 
• EU/International 
opportunities
HRB Strategy - Key Themes 
• Increase high quality, interdisciplinary 
health research 
• Enhance research partnerships, 
collaborations and networks 
• Focus on translation and application of 
knowledge 
• Enhance use of existing health and social 
data 
• Increase evidence-informed policy and 
practice
HRB Annual Income 1999-2012 
60.0 
50.0 
40.0 
30.0 
20.0 
10.0 
0.0 
1 2 3 4 5 6 7 8 9 10 
Total Income (€M) 
Year 
Capital (€M) 
Revenue (€M) 
1999 2001 2003 2005 2007 2008 2009 2010 2011 2012
HRB Portfolio analysis
Overview of HRB grant 
funding portfolio 
Projects & Programmes 
• Health Research Awards 
• Definitive Interventions 
• HRB/Medical Research Charity Group 
Awards 
Training/Career Development 
• Cochrane Training/Cochrane 
Fellowships 
• PhD Fellowships for Health and Social 
Care professionals (P/T and F/T) 
• Structured PhD Scholars -SPHERE 
• ICE Awards (post doc) 
• Research Leaders (Pop Health / HSR) 
• Clinician Scientists 
Centres and Research Networks 
• HRB Centre in Health and Diet 
Research 
• HRB Centre in Primary Care Research 
• All Ireland Institute in Hospice and 
Palliative Care – research network 
• Trials Methodology Network 
• Clinical Research Facilities (Dublin, 
Cork, Galway) 
• Clinical Trials Networks 
EU/International Opportunities 
• Horizon 2020 
• Wellcome Trust 
• US Ireland
Global and national context for 
primary care 
• Demographics – ageing population 
• More people living with chronic diseases 
• Shift in model from acute care to primary / 
community and self care 
• Shift from illness model to health and wellbeing 
• Emphasis on health promotion and behaviour 
change (lifestyle factors)
Case for primary care research 
• Need for an evidence base to support practice 
• Evidence to underpin clinical practice and healthcare 
policy must be obtained by R&D in primary care 
• Quality standards and protocols derive from research 
• Need research to inform policy on staffing, organisation 
or primary care 
• Process of conducting research important as the 
outcome 
• Involvement by primary care professionals in research 
leads to faster dissemination and adoption of research 
evidence
Issues for primary care research 
in Ireland* 
• Lack of infrastructure 
• Difficulties getting evidence implemented 
• Limited capacity of the primary care community 
to conduct research 
• Lack of any system for provision of payments to 
GPS to engage in research 
• Clinical academic career structure in primary 
care ‘unattractive’ 
* Mant Report 2006
HRB developments 
• Increased funding for health services, clinical research 
and patient research 
• Practical support through the TMRN (Trials Methodology 
Research Network) 
• Support for population or community based studies 
through the CRFs (Clinical Research Facilities) 
• Support for Primary care professionals through funding 
schemes, e.g. HPFs (note: few applications from GPs) 
• Investment in Centre for Primary Care Research (10 
years, €8 million) 
• Establishment of the Irish Primary Care Research 
Network
Themes in primary care research 
• Harnessing technology to improve primary care practice 
and health outcomes (e.g. access to primary care 
diagnostics) 
• Chronic disease management and multi-morbidity 
• Role of primary care in reducing inequalities in terms of 
access and health outcomes 
• Safer primary care (patient safety) 
• Evaluation of primary care reforms 
• Mental health and primary care 
• Workforce management in primary care 
• Role of primary care in health promotion and behaviour 
change
Examples of HRB funded 
primary care research projects 
• Framework for community involvement in decision making in primary 
care (Anne MacFarlane, Limerick) 
– Examined user involvement projects for quality, user experience and impact on 
service 
– Design a framework for the HSE to implement high quality user involvement 
projects 
• Developing and evaluating a complex intervention to influence quality 
and quantity of anti-microbial prescribing (Andrew Murphy, Galway) 
– Examining prescribing practices for urinary tract infections in Ireland and other 
countries 
– Evaluating interventions to reduce the amount of antibiotics prescribed 
• Towards early intervention for youth mental health (Walter Cullen, 
Limerick) 
– Developing an intervention to address barriers to ‘early intervention’ for mental and 
substance use disorders among young people
CPCR 
• Includes RCSI, TCD, NUIG and QUB 
• Focusing on 
– Safer medicines (safer prescribing, medicines management) 
– Safer diagnosis ( clinical decision support systems; generating and 
applying clinical prediction rules) 
– Evaluating intervention studies - in an elderly cohort, in a 
population of poorly controlled diabetes patients 
– More rational use of antibiotics 
– Managing multi-morbidity 
• Established the Irish Primary Care Network
iPCRN (Irish Primary Care 
Network) www.icprn.ie 
• Collaboration between the ICGP, the HRB Primary Care Research 
Centre (in RCSI) and WestRen (NUIG) 
• Aims to: 
o Establish a national network of GP practices whose purpose is to 
participate in clinical research for the benefit of their patients and 
o To enhance general practice through research training and activity 
• The iPCRN: 
o Facilitates GP's in maintaining The Medical Council's requirements 
for professional competence - particularly in in the areas of audit 
and research 
o Enables GP's to become more involved in planned research trial 
activities in the community 
o Enhances collaboration among network partners through access to 
literature, resources and training materials in research methodology 
o Provides General Practice with new applications/tools to audit and 
manage their patient care
Conclusions 
• Clear need for primary care research to improve service 
delivery 
• Key themes and questions for primary care research in 
Ireland 
• Need to encourage more primary care professionals 
(GPs, nurses, therapists, dentists) to engage in health 
services and clinical research 
• Need to work in multi and interdisciplinary partnerships 
for better research 
• Much improved environment for primary care research - 
support and infrastructure

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Mairead O'Driscoll, PhD Director, Research Strategy and Funding Directorate, Health Research Board

  • 1. Primary Care Conference 19 Nov 2014 Role of Research in Primary Care
  • 2. Overview • Strategic context for health research • Overview of HRB • Primary care research in Ireland • Examples of primary care research linked to practice
  • 3. Health Research Plans • HRG Action Plan for Health Research 2009-2013 • HRB Strategic Business Plan 2010 -2014 • National Research Prioritisation Exercise 2012 Set the strategic direction, goals, targets and actions to reap the health, social and economic benefits of our investment in health research
  • 4. 1. Patient-oriented research 2. Population Health 3. Health Services Research • Projects • Applied Programmes • Centres/networks • Short courses/workshops • Fellowships and Career Awards • Research Infrastructure • EU/International opportunities
  • 5. HRB Strategy - Key Themes • Increase high quality, interdisciplinary health research • Enhance research partnerships, collaborations and networks • Focus on translation and application of knowledge • Enhance use of existing health and social data • Increase evidence-informed policy and practice
  • 6. HRB Annual Income 1999-2012 60.0 50.0 40.0 30.0 20.0 10.0 0.0 1 2 3 4 5 6 7 8 9 10 Total Income (€M) Year Capital (€M) Revenue (€M) 1999 2001 2003 2005 2007 2008 2009 2010 2011 2012
  • 8. Overview of HRB grant funding portfolio Projects & Programmes • Health Research Awards • Definitive Interventions • HRB/Medical Research Charity Group Awards Training/Career Development • Cochrane Training/Cochrane Fellowships • PhD Fellowships for Health and Social Care professionals (P/T and F/T) • Structured PhD Scholars -SPHERE • ICE Awards (post doc) • Research Leaders (Pop Health / HSR) • Clinician Scientists Centres and Research Networks • HRB Centre in Health and Diet Research • HRB Centre in Primary Care Research • All Ireland Institute in Hospice and Palliative Care – research network • Trials Methodology Network • Clinical Research Facilities (Dublin, Cork, Galway) • Clinical Trials Networks EU/International Opportunities • Horizon 2020 • Wellcome Trust • US Ireland
  • 9. Global and national context for primary care • Demographics – ageing population • More people living with chronic diseases • Shift in model from acute care to primary / community and self care • Shift from illness model to health and wellbeing • Emphasis on health promotion and behaviour change (lifestyle factors)
  • 10. Case for primary care research • Need for an evidence base to support practice • Evidence to underpin clinical practice and healthcare policy must be obtained by R&D in primary care • Quality standards and protocols derive from research • Need research to inform policy on staffing, organisation or primary care • Process of conducting research important as the outcome • Involvement by primary care professionals in research leads to faster dissemination and adoption of research evidence
  • 11. Issues for primary care research in Ireland* • Lack of infrastructure • Difficulties getting evidence implemented • Limited capacity of the primary care community to conduct research • Lack of any system for provision of payments to GPS to engage in research • Clinical academic career structure in primary care ‘unattractive’ * Mant Report 2006
  • 12. HRB developments • Increased funding for health services, clinical research and patient research • Practical support through the TMRN (Trials Methodology Research Network) • Support for population or community based studies through the CRFs (Clinical Research Facilities) • Support for Primary care professionals through funding schemes, e.g. HPFs (note: few applications from GPs) • Investment in Centre for Primary Care Research (10 years, €8 million) • Establishment of the Irish Primary Care Research Network
  • 13. Themes in primary care research • Harnessing technology to improve primary care practice and health outcomes (e.g. access to primary care diagnostics) • Chronic disease management and multi-morbidity • Role of primary care in reducing inequalities in terms of access and health outcomes • Safer primary care (patient safety) • Evaluation of primary care reforms • Mental health and primary care • Workforce management in primary care • Role of primary care in health promotion and behaviour change
  • 14. Examples of HRB funded primary care research projects • Framework for community involvement in decision making in primary care (Anne MacFarlane, Limerick) – Examined user involvement projects for quality, user experience and impact on service – Design a framework for the HSE to implement high quality user involvement projects • Developing and evaluating a complex intervention to influence quality and quantity of anti-microbial prescribing (Andrew Murphy, Galway) – Examining prescribing practices for urinary tract infections in Ireland and other countries – Evaluating interventions to reduce the amount of antibiotics prescribed • Towards early intervention for youth mental health (Walter Cullen, Limerick) – Developing an intervention to address barriers to ‘early intervention’ for mental and substance use disorders among young people
  • 15.
  • 16. CPCR • Includes RCSI, TCD, NUIG and QUB • Focusing on – Safer medicines (safer prescribing, medicines management) – Safer diagnosis ( clinical decision support systems; generating and applying clinical prediction rules) – Evaluating intervention studies - in an elderly cohort, in a population of poorly controlled diabetes patients – More rational use of antibiotics – Managing multi-morbidity • Established the Irish Primary Care Network
  • 17. iPCRN (Irish Primary Care Network) www.icprn.ie • Collaboration between the ICGP, the HRB Primary Care Research Centre (in RCSI) and WestRen (NUIG) • Aims to: o Establish a national network of GP practices whose purpose is to participate in clinical research for the benefit of their patients and o To enhance general practice through research training and activity • The iPCRN: o Facilitates GP's in maintaining The Medical Council's requirements for professional competence - particularly in in the areas of audit and research o Enables GP's to become more involved in planned research trial activities in the community o Enhances collaboration among network partners through access to literature, resources and training materials in research methodology o Provides General Practice with new applications/tools to audit and manage their patient care
  • 18. Conclusions • Clear need for primary care research to improve service delivery • Key themes and questions for primary care research in Ireland • Need to encourage more primary care professionals (GPs, nurses, therapists, dentists) to engage in health services and clinical research • Need to work in multi and interdisciplinary partnerships for better research • Much improved environment for primary care research - support and infrastructure