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Lipid Transport and Storage Dr. Bibi Kulsoom Assistant Professor Department of Biochemistry
Countrywide Transport
Structure of Small Intestine
Structure of Small Intestine
Triglyceride Packing & Transport
Chylomicron A-II A-II
Lymphatic system
Blood Circulation
Chylomicron Apo C II, E B 48 E C II A II HDL
Deloading of Chylomicrons http://www.richmond.edu
Triacylgycerol Storage
Triacylgycerol Storage http://www.trudicanavan.com http://www.vivo.colostate.edu Brown Adipose Tissue
Chylomicron Transport to Liver
Countrywide Transport
Hepatic uptake of Chylomicron Remnants
Fate of Chylomicron Remnants Chol TG FFA PhoL
Secretion of VLDL
Lipoproteins
Lipoprotein Structure
 
Composition of Lipoproteins
Free Fatty acid Adipose tissue Free fatty acids with Albumin A-I, A-II, A-IV, C-I,C-II, C-III, D, E Phospholipids,   Cholesterol Liver, Intestine HDL B-100 Cholesterol IDL LDL B-100, E Triacylgycerol   VLDL IDL B-100, C-I, C-II, C-III Triacylgycerol,  Cholesterol Liver  VLDL B-48, E Triacylgycerol,   Phospholipids,   Cholesterol Chylomicron Chylomicron remnants A-I, A-II, A-IV, B-48, C-I, C-II, C-III, E Triacylgycerol   Intestine  Chylomicron Apolipoproteins Main Lipid Sources Lipoprotein
Apolipoproteins
Closely associated with LCAT. ApoD Inhibits LPL. ApoC-III Activates LPL. ApoC-II Probably activates LCAT. ApoC-I Binds to LDL receptors. ApoE Binds LDL receptor. ApoB-100 Contributes to structure. ApoB-48 Contributes to structure. ApoA-IV Enhanced hepatic lipase activity. ApoA-II Activates LCAT. ApoA-I Function Apoprotein
Triacylglycerol Transport
Bood circulation Harper’s Illustrated Biochemistry
Triacylglycerol & Cholesterol Transport
Harper’s Illustrated Biochemistry
Reverse Cholesterol Transport
Harper’s Illustrated Biochemistry
 
Dislioproteinemias ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
THANK YOU ,[object Object],[object Object],[object Object],Lipid Transport and Storage

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Lipid Transport And Storage