This document provides an overview of two's complement multiplication and division in computer organization and assembly language. It discusses how to perform two's complement multiplication by sign extending both integers to twice as many bits and taking bits from the least significant bit of the result. It also explains the process of division, which involves setting an initial quotient of 0, incrementing the quotient if the dividend is greater than or equal to the divisor, and finding the remainder using two's complement arithmetic. Examples of two's complement multiplication and division are provided to illustrate the concepts.