This document provides an overview of the CS-651 Intelligent Information Systems course for Spring 2022, taught by Khalid Saleem. It discusses key topics that will be covered, including data mining, knowledge discovery in databases, the differences between data, information, and knowledge. It also outlines different types of information systems like decision support systems, executive support systems, and transaction processing systems. Examples of real-world big data applications are provided, such as how Obama's 2012 re-election campaign used data analytics. Recommended readings for the course are listed at the end.