Kidney transplantation involves surgically placing a healthy donor kidney into a recipient with chronic renal failure. Donors can be living relatives or non-relatives, or cadavers. Recipients must be between 5-55 years old and free of systemic disease or infection. Post-operative nursing care includes monitoring urine output and function tests, as well as checking for complications like rejection or infection. Rejection occurs if the recipient's body attacks the new kidney and has acute or chronic forms. Nurses educate patients and families on medication adherence, infection prevention, and monitoring for rejection symptoms post-transplant.