The slides were used at Bio Korea 2016.
The topic is key success factors in digital healthcare and it deals with 3 topics: Utility, Business model, platform.
12 Gifts of Digital Health: How Futuristic Technologies Changed Healthcare an...Enspektos, LLC
When people talk about how digital technologies will influence health, many assume changes will happen years or decades into the future. Yet, in 2014 a range of digital tech, from Big Data to genomics, gave people the gift of life, knowledge and more. Look back at the year that was in digital health and understand that he future is now.
New Normal, New Future - Free Download E bookkevin brown
Healthcare is shifting from the traditional provider-centric,
in-patient setting to patient-centric, virtual consultations
with increased remote care monitoring. This transition
has prompted the need for MedTech industry to relook
at the products they develop and enhance value in care
delivery.
The COVID-19 pandemic has increased the use of
digital health technologies, and the need to develop
innovative devices or systems that support virtual
health. The last couple of years have seen increased
use of wearables, mobile and app-based technologies
along with data and analytics have been transforming
healthcare delivery.
Advancements in healthcare technologies like
Artificial Intelligence (AI), Virtual Reality and Augmented
Reality 3D-printing, robotics and nanotechnology are
shaping the future of healthcare. This technology boom
is helping address disease and medical conditions
through provision of cheaper, faster and more effective
solutions for diseases.
The FDA Digital Health Center of Excellence and the Advancement of Digital He...Greenlight Guru
The FDA Digital Health Center of Excellence is part of the planned evolution of the digital health program with the intent to drive synergy for digital health efforts, align strategy with implementation, prepare the FDA for the digital health future, and protect patients and maintain the FDA standards of safety and effectiveness.
Ultimately, the program works to strategically advance science and evidence for digital health technologies that meets the needs of
stakeholders.
This free in-depth webinar, presented by Matthew DiamondChief Medical Officer, Digital Health Center of Excellence, will cover the digital health landscape and areas of application, goals and outcomes, planned services and launch plan, and the current areas of focus - including AI/ML-Based SaMD.
This presentation originally aired during the 2021 State of Medical Device Virtual Summit.
The 10 most innovative medical devices companies 2018insightscare
Despite these challenges, medical device companies have always been adept with the latest technology and innovations happening in the sector. Keeping this in mind, we bring you the in-depth profiles of- “The 10 Most Innovative Medical Devices Companies 2018.”
Smart Patient Engagement Solutions for Physical Therapists and Rehabilitation...David Dansereau
My presentation will look at the benefits of harnessing new health technology and mobile health data to improve therapy services, promote wellness and awareness through better patient engagement and help improve medical research. I'll also cover what I believe the future holds for the mHealth industry with respect to rehabilitation and prevention, and what challenges lie ahead for providers that consider adopting these new methods of care delivery.
Note: This is based on my personal experience,interviews and research. Please keep and open mind as this is new territory for all of us!
12 Gifts of Digital Health: How Futuristic Technologies Changed Healthcare an...Enspektos, LLC
When people talk about how digital technologies will influence health, many assume changes will happen years or decades into the future. Yet, in 2014 a range of digital tech, from Big Data to genomics, gave people the gift of life, knowledge and more. Look back at the year that was in digital health and understand that he future is now.
New Normal, New Future - Free Download E bookkevin brown
Healthcare is shifting from the traditional provider-centric,
in-patient setting to patient-centric, virtual consultations
with increased remote care monitoring. This transition
has prompted the need for MedTech industry to relook
at the products they develop and enhance value in care
delivery.
The COVID-19 pandemic has increased the use of
digital health technologies, and the need to develop
innovative devices or systems that support virtual
health. The last couple of years have seen increased
use of wearables, mobile and app-based technologies
along with data and analytics have been transforming
healthcare delivery.
Advancements in healthcare technologies like
Artificial Intelligence (AI), Virtual Reality and Augmented
Reality 3D-printing, robotics and nanotechnology are
shaping the future of healthcare. This technology boom
is helping address disease and medical conditions
through provision of cheaper, faster and more effective
solutions for diseases.
The FDA Digital Health Center of Excellence and the Advancement of Digital He...Greenlight Guru
The FDA Digital Health Center of Excellence is part of the planned evolution of the digital health program with the intent to drive synergy for digital health efforts, align strategy with implementation, prepare the FDA for the digital health future, and protect patients and maintain the FDA standards of safety and effectiveness.
Ultimately, the program works to strategically advance science and evidence for digital health technologies that meets the needs of
stakeholders.
This free in-depth webinar, presented by Matthew DiamondChief Medical Officer, Digital Health Center of Excellence, will cover the digital health landscape and areas of application, goals and outcomes, planned services and launch plan, and the current areas of focus - including AI/ML-Based SaMD.
This presentation originally aired during the 2021 State of Medical Device Virtual Summit.
The 10 most innovative medical devices companies 2018insightscare
Despite these challenges, medical device companies have always been adept with the latest technology and innovations happening in the sector. Keeping this in mind, we bring you the in-depth profiles of- “The 10 Most Innovative Medical Devices Companies 2018.”
Smart Patient Engagement Solutions for Physical Therapists and Rehabilitation...David Dansereau
My presentation will look at the benefits of harnessing new health technology and mobile health data to improve therapy services, promote wellness and awareness through better patient engagement and help improve medical research. I'll also cover what I believe the future holds for the mHealth industry with respect to rehabilitation and prevention, and what challenges lie ahead for providers that consider adopting these new methods of care delivery.
Note: This is based on my personal experience,interviews and research. Please keep and open mind as this is new territory for all of us!
Digital therapeutics and immersive technologies Bournemouth UniversityDavid Wortley
Digital therapeutics is a fast growing area of digital medicine. In this presentation, Vice President of the International Society of Digital Medicine (ISDM), David Wortley, sets out the current challenges to global health sustainability and the importance of shifting the focus from cure to prevention, especially in the use of digital technologies for personal health management and therapeutics.
The presentation includes examples of digital therapeutic applications for neuro- rehabilitation, gamified exercise using consumer VR devices and support for dementia sufferers through digital memories.
The presentation was delivered at the new Faculty for Health and Social Sciences at Bournemouth University.
Digital Therapeutics (DTx) - Disruption in HealthcareDr. Mario Weiss
Digital therapeutics is the current disruption in healthcare and GAIA is leading the way. They are delivering effective and fully automated treatments/interventions for global medical needs.
What are Digital Therapeutics? What are Digital Therapeutics not? What qualifies software as therapy? How do we research and develop Digital Therapeutics ? Why can DTx be disruptive? Threats and Opportunities for Pharma
Created as a podcast for the Dental Informatics Online Community [http://www.dentalinformatics.com/], this is snapshot of what is going on with social technologies and Web 2.0 in various healthcare communities.
Digital Therapeutics / Digital Health Innovation Rawane Jabara
Ampersand & Ampersand is a digital health and therapeutics agency based in London. We specialise in co-developing clinically relevant software that puts patients at the heart of their health management. "Digital therapeutics represent a new generation of healthcare that uses innovative, clinically-validated disease management and direct treatment applications to enhance, and in some cases replace, current medical practices and treatments." - Digital Therapeutics Alliance. Check out our work here and get in touch. 3amp.com rawane@3amp.com
How Wearables will transform the EHR (Electronic Disease Record), slide deck for presentation by David Doherty (@mHealth) at Wearables Europe, London, 28 May 2015.
Patient leakage - What to know and how to avoid itChiron Health
Patient leakage to urgent care centers is a well known and costly issue for many practices. However, with the rise of telemedicine, there is a new aspect of patient leakage that practices need to be aware of: leakage to on-demand telemedicine companies.
"Enabling Individual Wellness through Computational Systems Biology, Cloud An...Hyper Wellbeing
"Enabling Individual Wellness through Computational Systems Biology, Cloud Analytics, Wearables, Machine Learning and More" - Riaan Conradie (Co-Founder, LifeQ)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
The future of healthcare: when mobile disappearsMatteo Penzo
In today’s digital world, mobile devices are the powerful bridges between a connected ecosystem of healthcare professionals, caregivers and patients. New developments in big data, wearable sensors and the application of social layers are shifting an industry that used to focus on curing diseases to one that emphasizes health and wellness. But the mass adoption of connected healthcare will only happen when solutions are designed to be intuitive and technologies are forgotten. The future of healthcare will happen when mobile disappears into the background, placing the patient in the center and in control of their lives.
Presentation of Vishal Gulati (Draper Esprit, Venture Partner; Horizon Discovery Group PLC, Board Director) at the Forum of the BioRegion of Catalonia, organized by Biocat.
> Digital health explosion
> What is ‘Digital Therapeutics’ (DTx)?
> History of DTx
> Digital Therapeutics Alliance (DTA)
> How does DTx work?
> Disease Mx via DTx
> Barriers in the adoption of DTx
> DTx market
> DTx in the post-COVID era
> DTx market boom in post-COVID era
> Future of DTx
> Regulatory aspects of DTx - USFDA
> DTx incorporation guidance by other regulators
> Conclusion
Healing Hands Clinic : Success Story of India's Best Piles, Fissure and Fistu...HealingHands3
Healing Hands Clinic (HHC) is a certified center of excellence for Piles, Fissure, and Fistula treatment in India. Our branches are present at Pune, Mumbai, Nashik, Banglore, Hyderabad, Jaipur, and Dubai. Each of the clinics has Internationally recognized surgeons and state-of-the-art facilities to provide holistic treatment for all.
To date, more than 1.5 lakh patients have been satisfactorily treated for their diseases at Healing Hands Clinic. A maximum number of Stapler surgeries in Asia has been performed at all the centers of HHC. The country’s first Laser Haemorrhoidoplasty ( LHP ) was performed at HHC.
Slides used to deliver presentation on Korean healthcare system overview. Main topics are: payer, healthcare delivery system, regulation, stakeholders.
Digital therapeutics and immersive technologies Bournemouth UniversityDavid Wortley
Digital therapeutics is a fast growing area of digital medicine. In this presentation, Vice President of the International Society of Digital Medicine (ISDM), David Wortley, sets out the current challenges to global health sustainability and the importance of shifting the focus from cure to prevention, especially in the use of digital technologies for personal health management and therapeutics.
The presentation includes examples of digital therapeutic applications for neuro- rehabilitation, gamified exercise using consumer VR devices and support for dementia sufferers through digital memories.
The presentation was delivered at the new Faculty for Health and Social Sciences at Bournemouth University.
Digital Therapeutics (DTx) - Disruption in HealthcareDr. Mario Weiss
Digital therapeutics is the current disruption in healthcare and GAIA is leading the way. They are delivering effective and fully automated treatments/interventions for global medical needs.
What are Digital Therapeutics? What are Digital Therapeutics not? What qualifies software as therapy? How do we research and develop Digital Therapeutics ? Why can DTx be disruptive? Threats and Opportunities for Pharma
Created as a podcast for the Dental Informatics Online Community [http://www.dentalinformatics.com/], this is snapshot of what is going on with social technologies and Web 2.0 in various healthcare communities.
Digital Therapeutics / Digital Health Innovation Rawane Jabara
Ampersand & Ampersand is a digital health and therapeutics agency based in London. We specialise in co-developing clinically relevant software that puts patients at the heart of their health management. "Digital therapeutics represent a new generation of healthcare that uses innovative, clinically-validated disease management and direct treatment applications to enhance, and in some cases replace, current medical practices and treatments." - Digital Therapeutics Alliance. Check out our work here and get in touch. 3amp.com rawane@3amp.com
How Wearables will transform the EHR (Electronic Disease Record), slide deck for presentation by David Doherty (@mHealth) at Wearables Europe, London, 28 May 2015.
Patient leakage - What to know and how to avoid itChiron Health
Patient leakage to urgent care centers is a well known and costly issue for many practices. However, with the rise of telemedicine, there is a new aspect of patient leakage that practices need to be aware of: leakage to on-demand telemedicine companies.
"Enabling Individual Wellness through Computational Systems Biology, Cloud An...Hyper Wellbeing
"Enabling Individual Wellness through Computational Systems Biology, Cloud Analytics, Wearables, Machine Learning and More" - Riaan Conradie (Co-Founder, LifeQ)
Delivered at the inaugural Hyper Wellbeing Summit, 14th November 2016, Mountain View, California.
For more information including details of subsequent events, please visit http://hyperwellbeing.com
The summit was created to foster a community around an emerging industry - Wellness as a Service (WaaS). Consumer technologies, in particular wearables and mobile, are powering a consumer revolution. A revolution to turn health and wellness into platform delivered services. A revolution enabling consumer data-driven disease risk reduction. A revolution extending health care past sick care towards consumer-led lifelong health, wellness and lifestyle optimization.
WaaS newsletter sign-up http://eepurl.com/b71fdr
@hyperwellbeing
The future of healthcare: when mobile disappearsMatteo Penzo
In today’s digital world, mobile devices are the powerful bridges between a connected ecosystem of healthcare professionals, caregivers and patients. New developments in big data, wearable sensors and the application of social layers are shifting an industry that used to focus on curing diseases to one that emphasizes health and wellness. But the mass adoption of connected healthcare will only happen when solutions are designed to be intuitive and technologies are forgotten. The future of healthcare will happen when mobile disappears into the background, placing the patient in the center and in control of their lives.
Presentation of Vishal Gulati (Draper Esprit, Venture Partner; Horizon Discovery Group PLC, Board Director) at the Forum of the BioRegion of Catalonia, organized by Biocat.
> Digital health explosion
> What is ‘Digital Therapeutics’ (DTx)?
> History of DTx
> Digital Therapeutics Alliance (DTA)
> How does DTx work?
> Disease Mx via DTx
> Barriers in the adoption of DTx
> DTx market
> DTx in the post-COVID era
> DTx market boom in post-COVID era
> Future of DTx
> Regulatory aspects of DTx - USFDA
> DTx incorporation guidance by other regulators
> Conclusion
Healing Hands Clinic : Success Story of India's Best Piles, Fissure and Fistu...HealingHands3
Healing Hands Clinic (HHC) is a certified center of excellence for Piles, Fissure, and Fistula treatment in India. Our branches are present at Pune, Mumbai, Nashik, Banglore, Hyderabad, Jaipur, and Dubai. Each of the clinics has Internationally recognized surgeons and state-of-the-art facilities to provide holistic treatment for all.
To date, more than 1.5 lakh patients have been satisfactorily treated for their diseases at Healing Hands Clinic. A maximum number of Stapler surgeries in Asia has been performed at all the centers of HHC. The country’s first Laser Haemorrhoidoplasty ( LHP ) was performed at HHC.
Slides used to deliver presentation on Korean healthcare system overview. Main topics are: payer, healthcare delivery system, regulation, stakeholders.
The Digital Health Technology Vision 2016 reveals five trends that prove winning in the digital age hinges on people. Keeping up with changing technology is vital, but it’s just as important to evolve the consumer experience, methods of care delivery and career development opportunities for the healthcare workforce.
20151022 디지털 헬스케어 임상시험 임상시험글로벌선도센터 심포지엄 v4Chiweon Kim
2015년 10월 22일 분당서울대병원에서 열렸던
임상시험글로벌선도센터 공동 심포지엄 'Information Technology in Clinical Trials'에서 발표한 자료입니다.
제 블로그에 올렸던 글들을 정리한 내용입니다.
아래 글들을 참고하세요
http://www.chiweon.com/?p=2547
http://www.chiweon.com/?p=2578
http://www.chiweon.com/?p=2593
http://www.chiweon.com/?p=2639
UX/UI의 전략적 접근: 스마트 헬스케어 사례 고찰
- 5가지 사례에서 길어 올린 스마트 헬스케어 UX/UI의 전략적 통찰
:Sproutel’s Jerry the Bear & A.C. Camargo Cancer Center’s Justice League
:Zeo Sleep Manager Pro
:Janssen’s Care4Today App and SMS
:AliveCor
:Fitness Shirt
- UX/UI, 우리에게 시사하는 것
mHealth Israel_US Hospitals: Overcoming Barriers to Adoption_Joe JankowskiLevi Shapiro
Webinar presentation for the mHealth Israel community by Joe Jankowski, PhD, Director, Innovation, Henry Ford Innovation Institute at the Henry Ford Health System in Detroit, Michigan. This is a systematic review of the key barriers inhibiting adoption of new technologies across health systems, with an emphasis on specific challenges for startups. Key factors include existing workflows, noise in the system, procurement cycle, costs, IT issues, self interests, value proposition, validation plan, Payer inefficiencies. Suggestion is to partner early, align to a major current problem and to focus on the health system rather than your own product. Also, build out a diverse team of stakeholders, use retrospective data to conduct scenario analysis, set appropriate expectations for time and cost.
mHealth Israel_Managing the Barriers to Customer Adoption_Lisa Prasad, Henry ...Levi Shapiro
Managing the Barriers to Customer Adoption- Presentation by Lisa Prasad, Managing Director, International, Henry Ford Innovation Institute at the Henry Ford Health System. Background about Provider efforts toward innovation, including status of Digital Transformation, impediments and barriers to adoption, persuading doctors / health care professionals, workflow challenges, activation constraints, procurement cycles, costs, IT integration and security, role of incumbents and practitioners, validation plans, payer inefficiencies,
Delivering high value healthcare through lean hospitalsglobalsevensteps
The demand for quality healthcare has never been so important with the recent episode of world wide challenges faced by the human race.
However, most hospitals are far from being humane and still working with outdated models. Demand and supply issues are widening the gap in providing quality healthcare.
marketing Strategy on Android App-Health plusBiswajeet Sahu
This was prepared during 4 weeks Marketing Internship under Prof.Sameer Mathur.
It contains an Android app with detailed Marketing Strategy and future plans after launching the app.
As consumers face more choice, complexity, and financial exposure for their health care in an increasingly uncertain world, they are highly influenced by Age , Income and Education factors.
James Dias, CEO, and Lucas Dailey, Senior User Experience Designer, will present a workshop, “Designing connected care solutions at the intersection of medicine and finance” on Saturday, September 6th from 2:20-3:50 PM PDT.
The workshop will explore how the business of performance-based healthcare requires a balance between giving patients the best possible quality outcomes and doing it in a cost effective manner. This emphasis on value-driven medicine is producing the opportunity for new technology solutions that address both care and costs. Designing effective solutions for “Connected Care” requires an interdisciplinary approach that brings together the disparate fields of healthcare economics, patient engagement, and digital technology.
5 Business Strategies to Grow Your Telehealth EnterpriseVSee
To carry on the discussion in real life, join us at Telehealth and Secrets to Success Conference, Sept 20-22, Silicon Valley:
https://goo.gl/95zHZG
For more information of the presentation such as recording and transcript, please visit: https://vsee.com/blog/5-business-strategies-to-grow-like-zocdoc/
For other webinars:
https://vsee.com/webinars/
Or join our Linkedin Group: https://www.linkedin.com/groups/Telehealth-Failures-Secrets-Success-13500037/about
Or Join our Facebook Group:
https://www.facebook.com/groups/tfssgroup/?ref=group_cover
Building Loyalty and Trust Through Continous EngagementYourCareUniverse
In the contemporary healthcare market, consumers are constantly evaluating their purchase decisions. The key to thriving in the age of increased competition and consolidation is to cultivate consumer loyalty by offering value over an extended period of time. This session will explore ways hospitals can drive engagement with their community by providing robust content and health and wellness tools to increase brand affinity.
Our guide to using applied behavioural economics within financial services to help improve customer outcomes.
Under pressure from the FCA, all financial services organisations are now expected to understand the principles of behavioural economics.
Beyond the compliance requirements, we are helping leading organisations to embed behavioural insights throughout the customer journey, supporting customer decision-making and boosting loyalty.
ANI | Demystifying the practice of Design Thinking | M R Ramakrishnan | 27 Se...AgileNetwork
Abstract:
Demonstration through example of how paying attention to the user and their context provides novel insights that shape the final outcome which wont have been possible without this approach.
Key Takeaways:
1. DT is for everyone
2. DT can be practised keeping in mind a 6 core principles
3. How to define a problem – in a noun and verb form
4. How to plan and conduct research
5. How to organize the output into manageable and meaningful tracks of work.
Think Tank VI Overview & Best PracticesJustin Barnes
We started the Health Innovation Think Tank 3 years ago to form a highly collaborative environment that creates and shares best practices as well as strategies to successfully navigate the future of healthcare
We cover 3 primary themes in this session: Care Strategy, Innovation and Leadership. Today is about education, collaboration as well as best practice & strategy sharing. Everyone here is unscripted and on the frontlines of healthcare.
User centricity, hypothesising and prototyping. These are some of the core principles of Design Thinking. By empathising with a group of people, these principles promise to reduce uncertainty about what problems to solve for whom and how.
Think Tank V Key Takeaways & Best PracticesJustin Barnes
Care Strategy, Care Collaboration, Innovation, Industry Disruptors & Social Determinants of Health best practices directly and unscripted from thought leaders on the front lines of healthcare
Easy Ways to Segment Your Customers and Create Actionsimagine.GO
Health care reform created millions of new health care shoppers. Many of whom visited your website for the first time. You've did the work to support the new health care consumer on your site, but did you converting visitors into shoppers, and shoppers into repeated customers? You can find the deck associated with this presentation here.
During this session we discussed:
1. How do you create and execute an effective segmentation strategy for health insurance shoppers?
2. Why Segment?
3. What Models?
4. What Methods?
5. What Results?
6. What Next?
Similar to Key Success factors in digital healthcare (20)
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
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Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
3. 4 questions digital healthcare products should address
No
Yes
No
Yes
No
Yes
No
Yes
Medical utility??
Recognized as
problem?
Does consumer
want solution?
Does it solve the
problem?
1. Utility
4. Product with utility but not regarded as a problem
Smart water bottle
•Drinking water helps improve health
•Do the consumers regard dehydration as
a problem?
•The bottle may be trying to solve a
problem that does not exist.
8. Zeo did not help solve the problem
Zeo sleep manager
•Monitors sleep pattern
•Once regarded as signature product
of digital health
•Stopped operation in 2013
•Reason for failure
limited meaning
Do not lead to sleep improvement
10. Need to have a clear view on utility
Medical Problem Wanna solve Solution
Utility evaluation
11. Digital healthcare’s utility for consumers
Utility for
Consumers
Short term
• Access to care
• Problem-based utility
-Triage
-Try to solve outside of
hospital
Mid-long term
• Behavioral modifiation
• Sustained use
16. Long term utility: Type 2 DM
• For chronic
diseases like
diabetes, the
most important
thing is
sustained
behavioral
change.
• Most of current
solutions for
diabetes focuses
on ancillary
problems rather
than the core
ones.
18. B2C: Digital healthcare is a credence good
Credence
good
Experience
good
Chracteristics
Search
good
Examples
• Can’t be judged even after it
is used
• Can’t be judged before it is
used
• Can be judged without being
used, if you spend enough time
to search
19. Insurance: Needs of insurance companies?
• Some insurance
companies offer
wearables to their
members
• Some members may try
to take advantage of
it
• Insurance companies
want heart rate
sensor to prevent the
fraud.
20. In Korea, only NHIS has enough motivation to invest in digital
healthcare
NHIS Private
payer
Consumer
Portion saved
by digital health
90%
10%
90%
10%
90%
10%
Private payer Consumer
90%
10%
90%
10%
Korea US
Digital healthcare’s impact on insurance depends on payer structure
21. Digital healthcare products fit into healthcare business structure
• Google glass case
• Google glass showed promise for use in
hospitals.
• However, the issue is who will pay for it
• Payer:?
• Hospital: ROI issue
• Doctors?
22. Platform is needed to connect products, consumers and hospitals.
Apple Healthkit
•Healthcare platform
•Major partners
EMR: Epic EMR
Hospital: Mayo clinic
•이후 연구를 위한 ResearchKit 과 ResearchKit
의 연구 결과를 앱으로 만들 수 있는 CareKit 출
시
Google Fit
•Focuses on fitness
•Partners: no hospitals or EMR companies
IT: LG, HTC, ASUS
Fitness, Sports: Nike, Adidas, Noom
3. Platform