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PROVEN TECHNOLOGY FOR
KERATOCONUS AND MORE
INTRACORNEAL RING SEGMENTS
TIME-TESTED, SAFE AND EFFECTIVE
TREATMENT FOR ECTATIC AND
IRREGULAR CORNEAS
Keraring intracorneal ring segments are surgically implantable
devices used to reduce corneal topographic irregularities, correct
low and high-order optical aberrations and improve visual acuity
in patients with keratoconus and other ectatic disorders.
Keraring was specifically designed to treat irregular
corneas and has been the treatment choice for hundreds
of thousands of patients globally for over 20 years with
excellent safety, efficacy and low complication rates.
Keraring’s clinical performance has been tested in multiple peer-
reviewed, independent scientific studies. A list of publications
and a summary of Keraring’s safety and clinical performance is
available and can be downloaded using the QR code below.
INTRACORNEAL RING SEGMENTS
INDICATIONS
• Keratoconus with reduced BSCVA
and contact lens intolerance
• Pellucid marginal degeneration
• Post Lasik ectasia
• High or irregular astigmatism following
corneal transplantation
Scientific publications
Scientific publications
and summary of safety
and summary of safety
and clinical performance
and clinical performance
FEATURES AND BENEFITS
EXCELLENT PATIENT SATISFACTION
Keraring patients consistently report highly
positive improvements in their quality of life.
QUICK VISUAL REHABILITATION
Minimally invasive surgical technique allows
patients to rapidly resume normal activities.
Topographic and visual changes are noticeable immediately
after the procedure and stabilize after 3 months on average.
COMPATIBLE WITH COMPLEMENTARY
TECHNIQUES
Keraring implantation can be synergistically
combined with other procedures such
as corneal collagen crosslinking,
photorefractive keratectomy (PRK) and
phakic intraocular lens implantation.
ADJUSTABILITY
When needed, Keraring can be
repositioned or exchanged to refine
the topographic and visual results.
REVERSIBILITY
Keraring explantation can be
performed at any time.
The procedure is reversible while
maintaining corneal integrity.
DOES NOT COMPROMISE
CORNEAL TRANSPLANTATION
Keraring implantation does not interfere
with the normal execution of a corneal
transplantation, if and when it is needed.
IMAGE COURTESY OF SERGIO KWITKO,M.D.
SURGICAL TECHNIQUE
KERARING® implantation is a quick outpatient procedure
usually carried out under topical anesthesia. Corneal
tunnel dissection can be performed by mechanic (manual)
or femtosecond laser assisted surgical techniques.
CLINICAL SUPPORT
Mediphacos offers permanent technical support to Keraring
surgeons. Please contact us at keraring@mediphacos.com
https://keraring.online
NOMOGRAMS
KERARING® implantation outcomes greatly
depend on the selection of implant size
and position for each individual case.
Mediphacos provides a surgical plan
nomogram as general orientation to
surgeons. The manufacturer nomogram
is available on the following link:
MECHANISM OF ACTION
• Corneal topographic regularization.
• Reduction in keratometry, refractive error and high-order
aberrations.
• Improvement of UDVA and CDVA.
• Improvement in spectacle and contact lens tolerance.
WHAT DO YOUR PEERS HAVE TO SAY?
“As an early adopter of intracorneal rings for keratoconus,
I have gone through the many phases of the technology.
Today, Keraring implantation is a time-tested, mature surgical
procedure that is essential to any modern corneal practice.”
Roberto Albertazzi, MD. (Buenos Aires – Argentina)
“Keraring is my implant of choice for corneal ectatic disorders due to the
constant innovation in designs, improved nomograms and excellent clinical
support. The wide product range allows me to tailor the treatment plan for
each individual patient.”
Delso Bonfante MD. (Chapecó – Brazil)
“Keraring implantation has been an essential tool in my keratoconus
practice for 20 years. My clinical experience exceeds 5000 eyes
implanted with highly positive results and low complication rates.”
Efekan Coskunseven MD. (Istanbul – Turkey)
“My long-term personal experience implanting intracorneal rings for
keratoconus agrees with the published scientific evidence. With correct
indication, execution and follow up, it is a highly safe and effective
procedure for keratoconus patients.”
Olivier Prisant MD. (Paris – France)
“In Israel and throughout the Middle East there is a high incidence of
keratoconus. I have successfully implanted Kerarings for many years, either as a
standalone procedure or in combination with other techniques such as corneal
collagen crosslinking. The addition of new Keraring progressive thickness models
has expanded indications, improved my outcomes and patient satisfaction.”
Adel Barbara MD. (Haifa – Israel)
“The management of keratoconus and corneal ectatic diseases evolved
tremendously, being a major part of Therapeutic Refractive Surgery.
Intracorneal ring segments have significant relevance in this new
specialty and are an important part of my practice. Patient selection and
education, individualized planning based on multimodal imaging, and
proper surgical technique using femtosecond lasers are the mainstays
for delivering great Keraring results and having happy patients.”
Renato Ambrosio Jr. MD PhD. (Rio de Janeiro – Brazil)
KERARING® is available in a wide selection
of models with variable optical zones, arc
lengths, thicknesses and thickness progression
profiles, providing surgeons with additional
options to address the different corneal
remodeling needs of individual patients.
WIDE CHOICE OF
IMPLANT SIZES
IMAGE COURTESY OF SERGIO KWITKO,M.D.
90 120 140 160 210 325
SI5
(5mm)
90 120 150 210 325
SI6
(6mm)
160W 160C 180MT 330MT 320
AS5
(5mm)
Asymmetric
160W 160C 150MT 180MT 330MT 320
AS6
(6mm)
Asymmetric
(1) Model developed in collaboration with Efekan Coskunseven MD. (Istanbul – Turkey)
(2) Model developed in collaboration with Delso Bonfante MD. (Chapecó – Brazil)
(3) Model developed in collaboration with Adel Barbara MD. (Haifa – Israel)
Not all models are available in every country. Check with your local Keraring distributor.
Keraring is presented with one intracorneal ring segment per box
07
Model
Arc length
(degrees)
Thickness
(um)
Thickness
Progression
Design
example
Profile view
SI5
90, 120, 140,
160, 210, 325 150, 200, 250
300, 350
Constant
thickness
SI6
90, 120, 150,
210, 325
320 200, 300, 400
Constant
thickness
AS5
160(1) 150/250
200/300
Thickness Increase
Clockwise (W) and
Counterclockwise (C)
180(2)
150/300
150/250
200/300
Greatest
thickness
on the center
of the arc (MT)
330(2) 150/250
200/300
320(2) 150/250/150
200/300/200
Sinusoidal
progression
AS6
160(1) 150/250
200/300
Thickness Increase
Clockwise (W) and
Counterclockwise (C)
150(3) 200/300
250/350 Greatest thickness
on the center of
the arc (MT)
180(2) 200/300
250/350
320(2) 150/250/150
200/300/200
Sinusoidal
progression
330(2) 200/300
250/350
Greatest thickness
on the center of
the arc (MT)
SECTION A-A
SECTION A-A
SECTION A-A
A
A
A
A
A
A
SECTION A-A
A
A
SECTION A-A
A
A
SECTION A-A
A
A
SECTION A-A
A
A
REV. 08 - 08/2023
Mediphacos is a world-class company with over 50 years of experience in ophthalmology and
international presence in more than 60 countries in 5 continents. Our mission is to restore,
preserve and improve human vision in collaboration with ophthalmologists through innovative,
safe and effective products and services.
Mediphacos has earned global presence and recognition through strong R&D investments,
state-of-the-art manufacturing technology and sharp focus on the evolving needs of eye care
professionals. In our modern manufacturing plant we employ exclusively the best materials and
technologies available worldwide, yielding innovative products of the highest quality, safety and
efficacy.
All Mediphacos products are designed and manufactured under a comprehensive quality
assurance system implemeted in all areas of the enterprise and certified in conformity to
stringent international quality standards.
mediphacos.com
www.keraring.online
@mediphacos
@mediphacoslatam

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KERARING brochure

  • 1. PROVEN TECHNOLOGY FOR KERATOCONUS AND MORE INTRACORNEAL RING SEGMENTS
  • 2. TIME-TESTED, SAFE AND EFFECTIVE TREATMENT FOR ECTATIC AND IRREGULAR CORNEAS Keraring intracorneal ring segments are surgically implantable devices used to reduce corneal topographic irregularities, correct low and high-order optical aberrations and improve visual acuity in patients with keratoconus and other ectatic disorders. Keraring was specifically designed to treat irregular corneas and has been the treatment choice for hundreds of thousands of patients globally for over 20 years with excellent safety, efficacy and low complication rates. Keraring’s clinical performance has been tested in multiple peer- reviewed, independent scientific studies. A list of publications and a summary of Keraring’s safety and clinical performance is available and can be downloaded using the QR code below. INTRACORNEAL RING SEGMENTS INDICATIONS • Keratoconus with reduced BSCVA and contact lens intolerance • Pellucid marginal degeneration • Post Lasik ectasia • High or irregular astigmatism following corneal transplantation Scientific publications Scientific publications and summary of safety and summary of safety and clinical performance and clinical performance
  • 3. FEATURES AND BENEFITS EXCELLENT PATIENT SATISFACTION Keraring patients consistently report highly positive improvements in their quality of life. QUICK VISUAL REHABILITATION Minimally invasive surgical technique allows patients to rapidly resume normal activities. Topographic and visual changes are noticeable immediately after the procedure and stabilize after 3 months on average. COMPATIBLE WITH COMPLEMENTARY TECHNIQUES Keraring implantation can be synergistically combined with other procedures such as corneal collagen crosslinking, photorefractive keratectomy (PRK) and phakic intraocular lens implantation. ADJUSTABILITY When needed, Keraring can be repositioned or exchanged to refine the topographic and visual results. REVERSIBILITY Keraring explantation can be performed at any time. The procedure is reversible while maintaining corneal integrity. DOES NOT COMPROMISE CORNEAL TRANSPLANTATION Keraring implantation does not interfere with the normal execution of a corneal transplantation, if and when it is needed. IMAGE COURTESY OF SERGIO KWITKO,M.D.
  • 4. SURGICAL TECHNIQUE KERARING® implantation is a quick outpatient procedure usually carried out under topical anesthesia. Corneal tunnel dissection can be performed by mechanic (manual) or femtosecond laser assisted surgical techniques. CLINICAL SUPPORT Mediphacos offers permanent technical support to Keraring surgeons. Please contact us at keraring@mediphacos.com https://keraring.online NOMOGRAMS KERARING® implantation outcomes greatly depend on the selection of implant size and position for each individual case. Mediphacos provides a surgical plan nomogram as general orientation to surgeons. The manufacturer nomogram is available on the following link: MECHANISM OF ACTION • Corneal topographic regularization. • Reduction in keratometry, refractive error and high-order aberrations. • Improvement of UDVA and CDVA. • Improvement in spectacle and contact lens tolerance.
  • 5. WHAT DO YOUR PEERS HAVE TO SAY? “As an early adopter of intracorneal rings for keratoconus, I have gone through the many phases of the technology. Today, Keraring implantation is a time-tested, mature surgical procedure that is essential to any modern corneal practice.” Roberto Albertazzi, MD. (Buenos Aires – Argentina) “Keraring is my implant of choice for corneal ectatic disorders due to the constant innovation in designs, improved nomograms and excellent clinical support. The wide product range allows me to tailor the treatment plan for each individual patient.” Delso Bonfante MD. (Chapecó – Brazil) “Keraring implantation has been an essential tool in my keratoconus practice for 20 years. My clinical experience exceeds 5000 eyes implanted with highly positive results and low complication rates.” Efekan Coskunseven MD. (Istanbul – Turkey) “My long-term personal experience implanting intracorneal rings for keratoconus agrees with the published scientific evidence. With correct indication, execution and follow up, it is a highly safe and effective procedure for keratoconus patients.” Olivier Prisant MD. (Paris – France) “In Israel and throughout the Middle East there is a high incidence of keratoconus. I have successfully implanted Kerarings for many years, either as a standalone procedure or in combination with other techniques such as corneal collagen crosslinking. The addition of new Keraring progressive thickness models has expanded indications, improved my outcomes and patient satisfaction.” Adel Barbara MD. (Haifa – Israel) “The management of keratoconus and corneal ectatic diseases evolved tremendously, being a major part of Therapeutic Refractive Surgery. Intracorneal ring segments have significant relevance in this new specialty and are an important part of my practice. Patient selection and education, individualized planning based on multimodal imaging, and proper surgical technique using femtosecond lasers are the mainstays for delivering great Keraring results and having happy patients.” Renato Ambrosio Jr. MD PhD. (Rio de Janeiro – Brazil)
  • 6. KERARING® is available in a wide selection of models with variable optical zones, arc lengths, thicknesses and thickness progression profiles, providing surgeons with additional options to address the different corneal remodeling needs of individual patients. WIDE CHOICE OF IMPLANT SIZES IMAGE COURTESY OF SERGIO KWITKO,M.D. 90 120 140 160 210 325 SI5 (5mm) 90 120 150 210 325 SI6 (6mm) 160W 160C 180MT 330MT 320 AS5 (5mm) Asymmetric 160W 160C 150MT 180MT 330MT 320 AS6 (6mm) Asymmetric
  • 7. (1) Model developed in collaboration with Efekan Coskunseven MD. (Istanbul – Turkey) (2) Model developed in collaboration with Delso Bonfante MD. (Chapecó – Brazil) (3) Model developed in collaboration with Adel Barbara MD. (Haifa – Israel) Not all models are available in every country. Check with your local Keraring distributor. Keraring is presented with one intracorneal ring segment per box 07 Model Arc length (degrees) Thickness (um) Thickness Progression Design example Profile view SI5 90, 120, 140, 160, 210, 325 150, 200, 250 300, 350 Constant thickness SI6 90, 120, 150, 210, 325 320 200, 300, 400 Constant thickness AS5 160(1) 150/250 200/300 Thickness Increase Clockwise (W) and Counterclockwise (C) 180(2) 150/300 150/250 200/300 Greatest thickness on the center of the arc (MT) 330(2) 150/250 200/300 320(2) 150/250/150 200/300/200 Sinusoidal progression AS6 160(1) 150/250 200/300 Thickness Increase Clockwise (W) and Counterclockwise (C) 150(3) 200/300 250/350 Greatest thickness on the center of the arc (MT) 180(2) 200/300 250/350 320(2) 150/250/150 200/300/200 Sinusoidal progression 330(2) 200/300 250/350 Greatest thickness on the center of the arc (MT) SECTION A-A SECTION A-A SECTION A-A A A A A A A SECTION A-A A A SECTION A-A A A SECTION A-A A A SECTION A-A A A
  • 8. REV. 08 - 08/2023 Mediphacos is a world-class company with over 50 years of experience in ophthalmology and international presence in more than 60 countries in 5 continents. Our mission is to restore, preserve and improve human vision in collaboration with ophthalmologists through innovative, safe and effective products and services. Mediphacos has earned global presence and recognition through strong R&D investments, state-of-the-art manufacturing technology and sharp focus on the evolving needs of eye care professionals. In our modern manufacturing plant we employ exclusively the best materials and technologies available worldwide, yielding innovative products of the highest quality, safety and efficacy. All Mediphacos products are designed and manufactured under a comprehensive quality assurance system implemeted in all areas of the enterprise and certified in conformity to stringent international quality standards. mediphacos.com www.keraring.online @mediphacos @mediphacoslatam