This chapter discusses the political economy of international trade. It covers topics such as instruments of trade policy including tariffs, subsidies, quotas, and antidumping policies. It also discusses arguments for and against government intervention in international trade such as protecting jobs versus increasing overall wealth. The development of the world trading system from GATT to the WTO is summarized. Key issues for the WTO including agriculture, intellectual property, and antidumping are outlined. The chapter concludes with implications for international business managers regarding trade barriers and government policy.