SlideShare a Scribd company logo
DELA PEÑA, K.
JOURNAL READING ON
AEROSOL THERAPY
Aerosol delivery aspects within a
highflow therapy system in COPD
patients
JOURNAL TITLE
Madney, Laz, Elberry, Rabea, and
Abdelrahim (2020) hypothesized that high-
flow therapy systems can provide the
respiratory support required by critically ill
patients.
On current problems. High-flow therapy is
efficient but requires temporary stopping of
gas flow to the patient.
SUMMARY
On methods. Madney et al (2020) investigated
the effects of a high-flow nasal cannula
(HFNC), a high-flow valved facemask (HFM),
and a high-flow mouthpiece (HMP) in terms of
lung deposition and systemic bioavailability of
salbutamol to manage COPD exacerbations.
SUMMARY
On result discussion. The use of HFNC was
reported to be the least efficient in terms of
delivering salbutamol to the lungs. Total
delivered salbutamol dose from 30-min and
24-urine samples were significantly lower
compared to HFN and HMP interface results.
However, reports show that the tolerability to
HFNC was higher receiving only 8% of patient
complaints while HFN and HMP received
33.3% and 50% patient complaints
respectively.
SUMMARY
In conclusion, amid significant differences in
drug deposition, all interfaces showed similar
lung function improvements. One deciding
factor of using these interfaces then depends
on patient comfort and tolerability.
SUMMARY
MY REACTION

More Related Content

Similar to JOURNAL READING ON AEROSOL THERAPY.pptx

High Flow Nasal canula by Dr.Mukesh.pptx
High Flow Nasal canula by Dr.Mukesh.pptxHigh Flow Nasal canula by Dr.Mukesh.pptx
High Flow Nasal canula by Dr.Mukesh.pptx
Dr.Mukesh Singh
 
Hfov presentation (abdul fattah)
Hfov  presentation (abdul fattah) Hfov  presentation (abdul fattah)
Hfov presentation (abdul fattah)
Abdul Fatah Abro
 
oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r]
 oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r] oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r]
oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r]
Luz Ch
 
Pneumonectomy
PneumonectomyPneumonectomy
Pneumonectomy
Dr.RMLIMS lucknow
 
High frequency ventilation.ppt
High frequency ventilation.pptHigh frequency ventilation.ppt
High frequency ventilation.ppt
Preetam Manoli
 
Mdi Presentation
Mdi PresentationMdi Presentation
Mdi Presentation
Kieran Lamb
 
use of antibiotics nebuliser.pdf
use of antibiotics nebuliser.pdfuse of antibiotics nebuliser.pdf
use of antibiotics nebuliser.pdf
ImranAhmad309
 
Controversies in critical care
Controversies in critical careControversies in critical care
Controversies in critical care
BalwinderRekhi
 
High flow nasal cannula (n dalmon)
High flow nasal cannula (n dalmon)High flow nasal cannula (n dalmon)
High flow nasal cannula (n dalmon)
Nicholas Dalmon
 
pulmonary drug delivery system
pulmonary drug delivery system pulmonary drug delivery system
pulmonary drug delivery system
Gujarat Technological University
 
High frequency oscillatory ventilation
High frequency oscillatory ventilationHigh frequency oscillatory ventilation
High frequency oscillatory ventilation
gnivri1666
 
Airway Pressure Release Ventilation
Airway Pressure Release VentilationAirway Pressure Release Ventilation
Airway Pressure Release Ventilation
Muhammad Asim Rana
 
Copd 9-837
Copd 9-837Copd 9-837
Copd 9-837
medlennin
 
Ann thoracmed 2015 Near fatal asthma
Ann thoracmed 2015 Near fatal asthmaAnn thoracmed 2015 Near fatal asthma
Ann thoracmed 2015 Near fatal asthma
Sherif Elbadrawy
 
NIV when to start ,How and when to end?
NIV when to start ,How and when to end?NIV when to start ,How and when to end?
NIV when to start ,How and when to end?
Gamal Agmy
 
Ards2
Ards2Ards2
Future directions in copd management
Future directions in copd managementFuture directions in copd management
Future directions in copd management
Waheed Shouman
 
Covid 19 mechanical ventilation managment
Covid 19 mechanical  ventilation managmentCovid 19 mechanical  ventilation managment
Covid 19 mechanical ventilation managment
Anwar Yusr
 
Cpap
Cpap Cpap
ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS)
ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS) ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS)
ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS)
Adel Hamada
 

Similar to JOURNAL READING ON AEROSOL THERAPY.pptx (20)

High Flow Nasal canula by Dr.Mukesh.pptx
High Flow Nasal canula by Dr.Mukesh.pptxHigh Flow Nasal canula by Dr.Mukesh.pptx
High Flow Nasal canula by Dr.Mukesh.pptx
 
Hfov presentation (abdul fattah)
Hfov  presentation (abdul fattah) Hfov  presentation (abdul fattah)
Hfov presentation (abdul fattah)
 
oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r]
 oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r] oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r]
oxygen therapy in covid-19 patients the role of hfnc and cpap (ferrari) [r]
 
Pneumonectomy
PneumonectomyPneumonectomy
Pneumonectomy
 
High frequency ventilation.ppt
High frequency ventilation.pptHigh frequency ventilation.ppt
High frequency ventilation.ppt
 
Mdi Presentation
Mdi PresentationMdi Presentation
Mdi Presentation
 
use of antibiotics nebuliser.pdf
use of antibiotics nebuliser.pdfuse of antibiotics nebuliser.pdf
use of antibiotics nebuliser.pdf
 
Controversies in critical care
Controversies in critical careControversies in critical care
Controversies in critical care
 
High flow nasal cannula (n dalmon)
High flow nasal cannula (n dalmon)High flow nasal cannula (n dalmon)
High flow nasal cannula (n dalmon)
 
pulmonary drug delivery system
pulmonary drug delivery system pulmonary drug delivery system
pulmonary drug delivery system
 
High frequency oscillatory ventilation
High frequency oscillatory ventilationHigh frequency oscillatory ventilation
High frequency oscillatory ventilation
 
Airway Pressure Release Ventilation
Airway Pressure Release VentilationAirway Pressure Release Ventilation
Airway Pressure Release Ventilation
 
Copd 9-837
Copd 9-837Copd 9-837
Copd 9-837
 
Ann thoracmed 2015 Near fatal asthma
Ann thoracmed 2015 Near fatal asthmaAnn thoracmed 2015 Near fatal asthma
Ann thoracmed 2015 Near fatal asthma
 
NIV when to start ,How and when to end?
NIV when to start ,How and when to end?NIV when to start ,How and when to end?
NIV when to start ,How and when to end?
 
Ards2
Ards2Ards2
Ards2
 
Future directions in copd management
Future directions in copd managementFuture directions in copd management
Future directions in copd management
 
Covid 19 mechanical ventilation managment
Covid 19 mechanical  ventilation managmentCovid 19 mechanical  ventilation managment
Covid 19 mechanical ventilation managment
 
Cpap
Cpap Cpap
Cpap
 
ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS)
ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS) ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS)
ACUTE RESPIRATORY DISTRESS SYNDROME. (ARDS)
 

Recently uploaded

Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
ayushrajshrivastava7
 
Know the difference between Endodontics and Orthodontics.
Know the difference between Endodontics and Orthodontics.Know the difference between Endodontics and Orthodontics.
Know the difference between Endodontics and Orthodontics.
Gokuldas Hospital
 
Histololgy of Female Reproductive System.pptx
Histololgy of Female Reproductive System.pptxHistololgy of Female Reproductive System.pptx
Histololgy of Female Reproductive System.pptx
AyeshaZaid1
 
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan PatroJune 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
Kanhu Charan
 
Pollen and Fungal allergy: aeroallergy.pdf
Pollen and Fungal allergy: aeroallergy.pdfPollen and Fungal allergy: aeroallergy.pdf
Pollen and Fungal allergy: aeroallergy.pdf
Chulalongkorn Allergy and Clinical Immunology Research Group
 
Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)
Josep Vidal-Alaball
 
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfNAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
Rahul Sen
 
Foundation of Yoga, YCB Level-3, Unit-1
Foundation of Yoga, YCB Level-3, Unit-1 Foundation of Yoga, YCB Level-3, Unit-1
Foundation of Yoga, YCB Level-3, Unit-1
Jyoti Bhaghasra
 
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdfMedical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Jim Jacob Roy
 
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga
 
How to choose the best dermatologists in Indore.
How to choose the best dermatologists in Indore.How to choose the best dermatologists in Indore.
How to choose the best dermatologists in Indore.
Gokuldas Hospital
 
The Nervous and Chemical Regulation of Respiration
The Nervous and Chemical Regulation of RespirationThe Nervous and Chemical Regulation of Respiration
The Nervous and Chemical Regulation of Respiration
MedicoseAcademics
 
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
MuskanShingari
 
5 Effective Homeopathic Medicines for Irregular Periods
5 Effective Homeopathic Medicines for Irregular Periods5 Effective Homeopathic Medicines for Irregular Periods
5 Effective Homeopathic Medicines for Irregular Periods
Dr. Deepika's Homeopathy - Gaur City
 
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
Université de Montréal
 
biomechanics of running. Dr.dhwani.pptx
biomechanics of running.   Dr.dhwani.pptxbiomechanics of running.   Dr.dhwani.pptx
biomechanics of running. Dr.dhwani.pptx
Dr. Dhwani kawedia
 
acne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticals
acne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticalsacne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticals
acne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticals
MuskanShingari
 
PARASITIC INFECTIONS IN CHILDREN peads.pptx
PARASITIC INFECTIONS IN CHILDREN peads.pptxPARASITIC INFECTIONS IN CHILDREN peads.pptx
PARASITIC INFECTIONS IN CHILDREN peads.pptx
MwambaChikonde1
 
Tele Optometry (kunj'sppt) / Basics of tele optometry.
Tele Optometry (kunj'sppt) / Basics of tele optometry.Tele Optometry (kunj'sppt) / Basics of tele optometry.
Tele Optometry (kunj'sppt) / Basics of tele optometry.
Kunj Vihari
 
Patellar Instability: Diagnosis Management
Patellar Instability: Diagnosis  ManagementPatellar Instability: Diagnosis  Management
Patellar Instability: Diagnosis Management
Dr Nitin Tyagi
 

Recently uploaded (20)

Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
Full Handwritten notes of RA by Ayush Kumar M pharm - Al ameen college of pha...
 
Know the difference between Endodontics and Orthodontics.
Know the difference between Endodontics and Orthodontics.Know the difference between Endodontics and Orthodontics.
Know the difference between Endodontics and Orthodontics.
 
Histololgy of Female Reproductive System.pptx
Histololgy of Female Reproductive System.pptxHistololgy of Female Reproductive System.pptx
Histololgy of Female Reproductive System.pptx
 
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan PatroJune 2024 Oncology Cartoons By Dr Kanhu Charan Patro
June 2024 Oncology Cartoons By Dr Kanhu Charan Patro
 
Pollen and Fungal allergy: aeroallergy.pdf
Pollen and Fungal allergy: aeroallergy.pdfPollen and Fungal allergy: aeroallergy.pdf
Pollen and Fungal allergy: aeroallergy.pdf
 
Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)Artificial Intelligence Symposium (THAIS)
Artificial Intelligence Symposium (THAIS)
 
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfNAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdf
 
Foundation of Yoga, YCB Level-3, Unit-1
Foundation of Yoga, YCB Level-3, Unit-1 Foundation of Yoga, YCB Level-3, Unit-1
Foundation of Yoga, YCB Level-3, Unit-1
 
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdfMedical Quiz ( Online Quiz for API Meet 2024 ).pdf
Medical Quiz ( Online Quiz for API Meet 2024 ).pdf
 
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdf
 
How to choose the best dermatologists in Indore.
How to choose the best dermatologists in Indore.How to choose the best dermatologists in Indore.
How to choose the best dermatologists in Indore.
 
The Nervous and Chemical Regulation of Respiration
The Nervous and Chemical Regulation of RespirationThe Nervous and Chemical Regulation of Respiration
The Nervous and Chemical Regulation of Respiration
 
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)
 
5 Effective Homeopathic Medicines for Irregular Periods
5 Effective Homeopathic Medicines for Irregular Periods5 Effective Homeopathic Medicines for Irregular Periods
5 Effective Homeopathic Medicines for Irregular Periods
 
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
“Psychiatry and the Humanities”: An Innovative Course at the University of Mo...
 
biomechanics of running. Dr.dhwani.pptx
biomechanics of running.   Dr.dhwani.pptxbiomechanics of running.   Dr.dhwani.pptx
biomechanics of running. Dr.dhwani.pptx
 
acne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticals
acne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticalsacne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticals
acne vulgaris -Mpharm (2nd semester) Cosmetics and cosmeceuticals
 
PARASITIC INFECTIONS IN CHILDREN peads.pptx
PARASITIC INFECTIONS IN CHILDREN peads.pptxPARASITIC INFECTIONS IN CHILDREN peads.pptx
PARASITIC INFECTIONS IN CHILDREN peads.pptx
 
Tele Optometry (kunj'sppt) / Basics of tele optometry.
Tele Optometry (kunj'sppt) / Basics of tele optometry.Tele Optometry (kunj'sppt) / Basics of tele optometry.
Tele Optometry (kunj'sppt) / Basics of tele optometry.
 
Patellar Instability: Diagnosis Management
Patellar Instability: Diagnosis  ManagementPatellar Instability: Diagnosis  Management
Patellar Instability: Diagnosis Management
 

JOURNAL READING ON AEROSOL THERAPY.pptx

  • 1. DELA PEÑA, K. JOURNAL READING ON AEROSOL THERAPY
  • 2. Aerosol delivery aspects within a highflow therapy system in COPD patients JOURNAL TITLE
  • 3. Madney, Laz, Elberry, Rabea, and Abdelrahim (2020) hypothesized that high- flow therapy systems can provide the respiratory support required by critically ill patients. On current problems. High-flow therapy is efficient but requires temporary stopping of gas flow to the patient. SUMMARY
  • 4. On methods. Madney et al (2020) investigated the effects of a high-flow nasal cannula (HFNC), a high-flow valved facemask (HFM), and a high-flow mouthpiece (HMP) in terms of lung deposition and systemic bioavailability of salbutamol to manage COPD exacerbations. SUMMARY
  • 5. On result discussion. The use of HFNC was reported to be the least efficient in terms of delivering salbutamol to the lungs. Total delivered salbutamol dose from 30-min and 24-urine samples were significantly lower compared to HFN and HMP interface results. However, reports show that the tolerability to HFNC was higher receiving only 8% of patient complaints while HFN and HMP received 33.3% and 50% patient complaints respectively. SUMMARY
  • 6. In conclusion, amid significant differences in drug deposition, all interfaces showed similar lung function improvements. One deciding factor of using these interfaces then depends on patient comfort and tolerability. SUMMARY