1. Help me I
become a yellow
man

2. Why I have this color ?
Jaundice is caused by increased amounts of bilirubin
in the blood.
Bilirubin is a by-product of the daily natural
breakdown and destruction of red blood cell in the
body. The hemoglobin molecule that is released into
the blood by this process is split, with the heme portion
undergoing a chemical conversion to bilirubin.
Normally, the liver metabolizes and excretes the
bilirubin in the form of bile. However, if there is a
disruption in this normal metabolism and/or
production of bilirubin, jaundice may result.

3. Causes of jundice
 Pre-hepatic (before bile is made in the liver):
 Malaria, sickle cell cerise's, spherocytosis, thalassimia ,
deficiency (G6PD),drugs or other toxins, and autoimmune
disorders.
 Hepatic (the problem arises within the liver):
 hepatitis (commonly viral or alcohol related),cirrhosis, drugs
or other toxins, Crigler-Najjar syndrome, gilbert's syndrome
and cancer .
 Post-hepatic (after bile has been made in the liver):
 gallstone in the bile ducts, cancer (pancreatic and
gallbladder/bile duct carcinoma),strictures of the bile ducts,
cholongitis ,congenital malformations, pancritis,
parasites,pregnancy and newborn jaundice .

4. Type of jaundice
 acholuric jaundice jaundice without bilirubinemia, associated with
elevated unconjugated bilirubin that is not excreted by the kidney.
 acholuric familial jaundice hereditary spherocytosis.
 breast milk jaundice elevated unconjugated bilirubin in some
breast-fed infants due to the presence of 5-β-pregnane-3-α-20-β-diol in
breast milk, which inhibits glucuronyl transferase conjugating activity,
or to dehydration.
 cholestatic jaundice that resulting from abnormal bile flow in the
liver.
 hemolytic jaundice that due to increased production of bilirubin
from hemoglobin under conditions causing accelerated degradation of
erythrocytes.
 hepatocellular jaundice that due to injury to or disease of liver
cells.
 hepatogenic jaundice , hepatogenous jaundice that due to
disease or disorder of the liver.

5. Type of Jaundice
 leptospiral jaundice Weil's syndrome.
 mechanical jaundice obstructive j.
 neonatal jaundice , jaundice of the newborn
icterus neonatorum..
 nuclear jaundice kernicterus.
 obstructive jaundice that due to blocking of bile flow.
 physiologic jaundice mild icterus neonatorum lasting
the first few days of life.
 retention jaundice that due to inability of the liver to
dispose of the bilirubin provided by the circulating blood.

6. Newborn Jaundice

7. Jaundice symptoms
yellow discoloration
of the skin, mucous
membranes, and the
whites of the eyes.
light-colored
stools,
dark-colored
urine
Abdominal pain
Nausea and
vomiting
itching
Fever and
weakness
Wight loss (loss
of appetite)
swelling of the
legs and
abdomen