ISMRM 2009, Honolulu

This document discusses two methods for calculating the impulse response function h(t) from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) data: an analytical solution based on a physiological model and a numerical deconvolution method that directly calculates h(t) from the tissue and blood contrast agent curves without a model. It also notes that numerical deconvolution is sensitive to truncation and lag-time corrections of the curves.