This document discusses innovation in FinTech, IoT, AI and cloud computing. It outlines 7 guiding principles for breakthrough innovation: Diversity, Explore, DIY, Re-use, Agile, Platform, and Digital. It also discusses two personal stories of innovation: defining FinTech and the citizen science platform SAFECAST, which revolutionized data collection through open data and community participation. The document advocates for open innovation, ecosystems, diversity of skills and thinking outside traditional structures to drive digital transformation.