During my internship at Mascure Pharma Industries, I had the opportunity to gain practical exposure to the pharmaceutical sector and understand the processes involved in drug development, quality assurance, and industrial operations. The training focused on familiarizing interns with Good Manufacturing Practices (GMP), safety protocols, and the importance of maintaining high-quality standards in pharmaceutical production. I was introduced to various departments such as production, quality control, and packaging, where I observed and learned about the preparation of formulations, testing procedures for raw materials and finished products, as well as labeling and compliance with regulatory guidelines.

1. HINDUSTHAN COLLEGE OF ENGINEERING AND TECHNOLOGY
(An Autonomous Institution, Affiliated to Anna University, Chennai)
Valley Campus, Pollachi Highway, Coimbatore - 641032
DEPARTMENT OF CHEMICAL ENGINEERING
INTERNSHIP
on
MACSUR PHARMACY INDIA PVT LTD – PONDICHERRY
Submitted By
MADHUMITHA S (720722114025)
ANNA UNIVERSITY: CHENNAI 600 025
Nov 2025

2. ABOUT THE INDUSTRY
Macsur Pharmacy India Pvt Ltd, located in Pondicherry,
is a reputed pharmaceutical manufacturing company
engaged in the production of a wide range of dosage
forms including tablets, syrups, capsules, and
ointments.The company operates under strict WHO-GMP
guidelines and adheres to quality control measures to
ensure safety and efficacy.Their mission is to provide
high-quality, affordable medicines to improve healthcare
outcomes in India and abroad.

3. PRODUCTS MANUFACTURED
 Tablets: Paracetamol, Diclofenac, Multivitamin
 Antihistamines Syrups: Cough Syrups, Vitamin Syrups Antacid
 Suspensions Capsules: Antibiotics
 Multivitamins Ointments: Analgesic creams, Antifungal creams.
 Other Dosage Forms: Sachets, Oral Drops

4. TABLET MANUFACTURING PROCESS
STAGES:
 Weighing & Dispensing
 Mixing & Granulation
 Drying
 Blending & Lubrication
 Compression
 Coating
 Packaging

5. WEIGHING & DISPENSING
 Raw materials are weighed accurately
according to the batch manufacturing
record.
 Conducted in a dust-free, controlled
environment.
 Prevents contamination and ensures correct
formulation.
 Documentation maintained as per SOPs.
MIXING & GRANULATION
 Active ingredients and excipients
blended to achieve uniformity.
 Wet granulation carried out using binder
solution to form granules.
 Equipment: Rapid Mixer Granulator
(RMG).
 Ensures proper flow properties and
compression characteristics.

6. DRYING
 Purpose: Remove excess
moisture from granules to
prevent microbial growth.
 Equipment: Fluid Bed Dryer
(FBD).
 Controlled temperature and air
flow prevent degradation of
active ingredients.
BLENDING & LUBRICATION
 Dried granules blended with lubricants (e.g., magnesium
stearate).
 Improves flowability and prevents sticking during
compression.
 Final blending ensures uniform distribution of ingredients.

7. COMPRESSION
 Tablets formed using a rotary tablet
press.
 In-process checks include hardness,
thickness, friability, and weight
variation.
 Ensures uniform tablet quality and
appearance.
COATING
Types: Film coating, sugar coating, and enteric coating.
Purpose: Protect the drug, mask unpleasant taste, control
release profile.
Equipment: Auto coater with spray system.

8. PACKAGING
 Methods: Blister packing,
strip packing, and bottle
filling.
 Includes batch coding,
manufacturing and expiry
date labelling.
 Final inspection ensures
product quality before
dispatch.
SYRUP MANUFACTURING PROCESS
Stages: Weighing of ingredients Dissolution
of sugar in purified water Addition of active
ingredients and flavours FiltrationFilling
into bottles Labelling and packing

9. DETAILED SYRUP PRODUCTION
 Sugar dissolved in heated purified water in
dissolution tank.
 Active ingredients, flavours, and colours added under
stirring.
 Filtration removes undissolved particles.
 Bottling and labelling done under sterile conditions.
QUALITY CONTROL
 Raw Material Testing: Identity, purity, and
strength.
 In-Process Testing: pH, viscosity, weight
variation, assay.
 Finished Product Testing: Dissolution, content
uniformity, stability.
 Compliance with pharmacopeial standards
(IP/BP/USP).

10. MY ROLE & LEARNINGS
 Observed and assisted in tablet and syrup manufacturing.
 Learned Good Manufacturing Practices (GMP) and
documentation procedures.
 Participated in quality control checks.
 Understood large-scale pharmaceutical manufacturing
and quality systems.

11. PROCESS FLOW CHART

12. QUALITY ANALYSIS
Quality Analysis Lab Sample Water From Tank
 pH analysis
 Total Dissolved Solids (TDS)
 Total Hardness
 Alkalinity
 Biochemical Oxygen Demand (BOD)
 Chemical Oxygen Demand (COD)
 Chloride Test
 Sulfate Test
 Nitrate Test
 Residual Chlorine
 Heavy Metals Analysis

13. CERTIFICATES

14. CONCLUSION & OUTCOME
 Internship provided hands-on exposure to pharmaceutical production
processes.
 Enhanced understanding of GMP, QC, and QA in manufacturing.
 Strengthened technical skills and prepared for a career in
pharma/chemical industries.