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From innovation to commercialization  Willem de Laat Managing Director Life Sciences & Health 8 December 2010
From innovation to commercialization
Global biomedical trends ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Global R&D spending 1.  Roche  - $8.7B 2.  Pfizer  - $7.4B 3.  Novartis  - $7.06B 4.  Johnson & Johnson  - $6.66B 5.  Sanofi-Aventis  - $6.25B 6.  GlaxoSmithKline  -  $5.59B 7.  Merck  - $5.58B 8.  Takeda Pharmaceuticals  - $4.64B 9.  AstraZeneca  - $4.23B  10.  Eli Lilly  - $4.13B 11.  Bristol-Myers Squibb  - $3.48B 12.  Boehringer Ingelheim  - $3.03B 13.  Abbott Laboratories  - $2.61B 14.  Daiichi Sankyo  - $1.89B 15.  Astellas Pharma  - $1.63B
H ealth-related life sciences : an important sector in the Dutch economy Drugs Diagnostics Devices Companies Revenues FTE Other Total Source: EIM study for EZ [2006] , Voorstel LSG [2006] Preliminary data Biotech Outlook 2011 430 390 75 935 40 12.0 bn 2.7 bn 0.6 bn 15.7 bn 0.4 bn 37,000 12,000 54,600 3,400 ± 150 companies highly innovative Update 2010: >200 companies highly innovative 3% of GDP 2,200
The Dutch life sciences and health innovation cluster builds upon a strong knowledge base Excellent biobanks and ‘real life’ data infrastructure 120 mile radius Global players & very high concentration of SMEs Excellent universities
5 of the top 10 European biotech deals are with Dutch companies, with a total value exceeding USD 2 billion
But....the consolidation changing environment has impact on the Netherlands Organon Solvay Crucell
Life Sciences & Health Innovation Program Improving the investment and innovation climate in the Dutch life sciences and health sector Hier komt een screenshot van de homepage 7 dec 5000+ unique visitors/month Database for subsidies and funding Benchmark study on  clinical trial performance  to map the competitive  position of  the Netherlands BIO - E UROPE  S PRING MARCH 14-16, 2011, MILAN, ITALY Thomson  Pharma Bio International Convention, Chicago, 2010
Biotech Outlook 2011 will be launched in  Q1 next year ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Progress
Sector vision 300 downloads
“ TOPGEBIED LIFE SCIENCES” We have to Build, Nurture and  Promote it together Health  &  Wealth
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
www.lifescienceshealth.com

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Innovation to commercialization

  • 1. From innovation to commercialization Willem de Laat Managing Director Life Sciences & Health 8 December 2010
  • 2. From innovation to commercialization
  • 3.
  • 4. Global R&D spending 1. Roche - $8.7B 2. Pfizer - $7.4B 3. Novartis  - $7.06B 4. Johnson & Johnson  - $6.66B 5. Sanofi-Aventis - $6.25B 6. GlaxoSmithKline -  $5.59B 7. Merck  - $5.58B 8. Takeda Pharmaceuticals - $4.64B 9. AstraZeneca - $4.23B 10. Eli Lilly - $4.13B 11. Bristol-Myers Squibb - $3.48B 12. Boehringer Ingelheim  - $3.03B 13. Abbott Laboratories - $2.61B 14. Daiichi Sankyo - $1.89B 15. Astellas Pharma - $1.63B
  • 5. H ealth-related life sciences : an important sector in the Dutch economy Drugs Diagnostics Devices Companies Revenues FTE Other Total Source: EIM study for EZ [2006] , Voorstel LSG [2006] Preliminary data Biotech Outlook 2011 430 390 75 935 40 12.0 bn 2.7 bn 0.6 bn 15.7 bn 0.4 bn 37,000 12,000 54,600 3,400 ± 150 companies highly innovative Update 2010: >200 companies highly innovative 3% of GDP 2,200
  • 6. The Dutch life sciences and health innovation cluster builds upon a strong knowledge base Excellent biobanks and ‘real life’ data infrastructure 120 mile radius Global players & very high concentration of SMEs Excellent universities
  • 7. 5 of the top 10 European biotech deals are with Dutch companies, with a total value exceeding USD 2 billion
  • 8. But....the consolidation changing environment has impact on the Netherlands Organon Solvay Crucell
  • 9. Life Sciences & Health Innovation Program Improving the investment and innovation climate in the Dutch life sciences and health sector Hier komt een screenshot van de homepage 7 dec 5000+ unique visitors/month Database for subsidies and funding Benchmark study on clinical trial performance to map the competitive position of the Netherlands BIO - E UROPE S PRING MARCH 14-16, 2011, MILAN, ITALY Thomson Pharma Bio International Convention, Chicago, 2010
  • 10.
  • 11. Sector vision 300 downloads
  • 12. “ TOPGEBIED LIFE SCIENCES” We have to Build, Nurture and Promote it together Health & Wealth
  • 13.

Editor's Notes

  1. EIM Report: Het cluster drugs bestaat uit bedrijven waarvoor geneesmiddelen en vaccins de belangrijkste afzetmarkten vormen. Ongeveer 44% van alle bedrijven (circa 430) maakt hier deel van uit. Zij tekenen voor een gezamenlijke om-zet van € 12 miljard en herbergen circa 37.000 werknemers, waarvan er 6.300 werkzaam zijn op R&D-gebied. In dit cluster zitten vanzelfsprekend ook veel farmaceutische bedrijven Het cluster diagnostics bevat bedrijven waarvoor diagnostische stoffen, bio-informatica, imaging en andere diagnostische apparatuur de belangrijkste deelmarkten zijn. Ongeveer 40% van de bedrijven (circa 390) maakt hier deel van uit. Zij zijn goed voor een totale omzet van € 2,7 miljard en voor een totale werkgelegenheid van ruim 12.000, waaronder bijna 2.000 R&D-werknemers. Het cluster biomedical engineerig & devices herbergt bedrijven waarvoor cel-enigineering, biomaterialen en kunstorganen belangrijke afzetmarkten vormen. Ongeveer 75 bedrijven maken hier deel van uit (7,6% van het to-taal); het cluster is goed voor een omzet van € 560 miljoen. In dit cluster zijn 3.400 personen, waarvan de helft op R&D-gebied. Cluster divers omvat bedrijven die binnen de Life Sciences & Gezondheid sector werkzaam zijn en waarvoor overige medische instrumenten de be-langrijkste afzetmarkt vormen. Ruim 40 bedrijven maken hier deel van uit. Omzet: € 400 miljoen. Dit cluster herbergt 2.200 werkzame personen waar-van ongeveer 10% wordt ingezet op R&D-gebied. drijven, waaronder enkele grote.
  2. That was the past…Today the life sciences sector is not just blooming in Amsterdam, but in the whole of the Netherlands. In 2009 the Netherlands features a highly innovative, world leading, concentrated and growing cluster of life sciences companies academia , covering a wide variety of clinical areas. A recent OECD study showed that the focal areas in the West and South of the Netherlands are among the leading clusters in the world for generation biotech patents
  3. Our approach is paying off In 2008 a strong growth in attracted venture capital against all odds In the top 10 European biotech-Pharma partnerships, 5 involve Dutch SME’s An example: Prosensa and its partnership with GSK - Development and commercialization of RNA based therapeutics for Duchenne Muscular Dystrophy (DMD) - Deal value of upfront and milestone payments USD 655 million
  4. Handen in elkaar slaan Cahier 300x gedownload
  5. Handen in elkaar slaan